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Mitochondrial disorders

Mitochondrial genetic disordersMitochondrial diseases
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 71-80 of 239 results.
Energy Metabolism in Branched-chain Organic Acidemias
Status: Completed
Last Changed: Apr 16, 2019
First Received: Apr 16, 2019
Disease(s): Energy Metabolism, Metabolic Syndrome, Insulin Resistance
Intervention(s): No intervention
Locations: Department of General Pediatrics, Neonatology and Pediatric Cardiology of the University Children's Hospital Düsseldorf, Düsseldorf, NRW, Germany
Institute for Clinical Diabetology, German Diabetes Center, Düsseldorf, NRW, Germany
Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort
Status: Completed
Last Changed: Feb 10, 2017
First Received: Nov 06, 2008
Disease(s): Metabolic Syndrome, Type 2 Diabetes Mellitus
Intervention(s): Diffuse Optical Spectroscopy
Locations: Beckman Laser Institute Medical clinic, Irvine, California, United States
Measures of Mitochondria Dysfunction in PD
Status: Recruiting
Last Changed: Mar 09, 2020
First Received: Mar 09, 2020
Disease(s): Parkinson Disease, Mitochondrial
Locations: University of Washington, Seattle, Washington, United States
Longitudinal Study of Mitochondrial Hepatopathies
Status: Suspended
Last Changed: Apr 02, 2020
First Received: Jun 22, 2010
Disease(s): Acute Liver Failure, Mitochondrial Diseases, End Stage Liver Disease, Respiratory Chain Deficiencies, Mitochondrial, Disorder of Fatty Acid Oxidation
Locations: Children's Hospital Los Angeles, Los Angeles, California, United States
University of California at San Francisco (UCSF), San Francisco, California, United States
Children's Hospital Colorado, Aurora, Colorado, United States
Children's Healthcare of Atlanta - Emory University, Atlanta, Georgia, United States
Ann & Robert H. Lurie Children's Hospital, Chicago, Illinois, United States
... and 12 other locations.
Safety, Tolerability and Pharmacokinetic Study of KL1333 in Healthy Male Volunteers
Status: Completed
Last Changed: Apr 27, 2018
First Received: Feb 17, 2017
Disease(s): MELAS Syndrome, Mitochondrial Respiratory Chain Deficiencies
Intervention(s): KL1333 25 mg, KL1333 50 mg, KL1333 100 mg, KL1333 200 mg, KL1333 400 mg, KL1333 600 mg, KL1333 800 mg, Placebo
Locations: Seoul National University Hospital, Seoul, Jongno-gu, Korea, Republic of
Imaging Neuromelanin and Iron in Dystonia/Parkinsonism
Status: Not yet recruiting
Last Changed: Jun 28, 2018
First Received: Jun 28, 2018
Disease(s): Sporadic Dystonia, Dystonia, Familial, Parkinson Disease, Juvenile, Neurodegeneration With Brain Iron Accumulation 5, Mitochondrial Diseases
Intervention(s): 3Tesla MRI, Burke-Fahn-Marsden Dystonia Rating scale, MDS-United Parkinsons Disease Rating Scale, Part III, Beck Depression Inventory, MoCA: Montreal Cognitive Assessment:
Phase 2a Study of IW-6463 in Adults Diagnosed With MELAS
Status: Not yet recruiting
Last Changed: Jul 27, 2020
First Received: Jul 17, 2020
Disease(s): MELAS
Intervention(s): IW-6463 Tablets
Nicotinamide Riboside and Mitochondrial Biogenesis
Status: Recruiting
Last Changed: Jul 08, 2019
First Received: Feb 14, 2018
Disease(s): Mitochondrial Diseases, Mitochondrial Myopathies, Progressive External Ophthalmoplegia, Progressive Ophthalmoplegia, Progressive; Ophthalmoplegia, External, Mitochondria DNA Deletion, MELAS, Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-Like Episodes, Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-Like Episodes (MELAS Syndrome)
Intervention(s): Nicotinamide Riboside
Locations: Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom
Phase 2 Study of EPI-743 in Children With Pearson Syndrome
Status: Terminated
Last Changed: Aug 31, 2020
First Received: Apr 04, 2014
Disease(s): Pearson Syndrome
Intervention(s): EPI-743
Locations: Children's Hospital of Orange County, Orange, California, United States
Cleveland Clinic, Cleveland, Ohio, United States
Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
Baylor College of Medicine, Houston, Texas, United States
Acute Nutritional Ketosis in VLCAD Deficiency
Status: Completed
Last Changed: May 21, 2018
First Received: May 21, 2018
Disease(s): VLCAD Deficiency, Fatty Acid Oxidation Defects
Intervention(s): ketone ester drink, exercise, muscle biopsy, Magnetic Resonance Imaging
Locations: Academic Medical Center, Amsterdam, Noord-Holland, Netherlands
Dept of Neuroscience/ Neuroimaging Center, Groningen, Netherlands