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Mitochondrial disorders

Mitochondrial genetic disordersMitochondrial diseases
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 61-70 of 239 results.
Safety, Tolerability, and Efficacy of MTP-131 for the Treatment of Mitochondrial Myopathy
Status: Completed
Last Changed: Dec 27, 2019
First Received: Feb 20, 2015
Disease(s): Mitochondrial Myopathy
Intervention(s): elamipretide (low dose), elamipretide (intermediate dose), elamipretide (high dose), Placebo
Locations: University of California, San Diego, California, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
Akron Children's Hospital, Akron, Ohio, United States
Children's Hospital of Pittsburg of UPMC, Pittsburgh, Pennsylvania, United States
Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
Status: Withdrawn
Last Changed: Apr 13, 2015
First Received: Nov 15, 2011
Disease(s): Chronic Fatigue Syndrome
Intervention(s): Nutraceutical supplements, Placebo
Locations: Columbia University Department of Clinical Genetics, New York, New York, United States
A Dose-escalating Clinical Trial With KH176
Status: Completed
Last Changed: Feb 08, 2016
First Received: Sep 09, 2015
Disease(s): MELAS, LHON, Leigh Syndrome, Mitochondrial Disease, Mitochondrial DNA tRNALeu(UUR) m.3243A
Intervention(s): KH176, placebo
Locations: Drug Research Unit Ghent, Ghent, Belgium
Natural History of Pearson Syndrome
Status: Completed
Last Changed: Aug 21, 2020
First Received: Dec 30, 2014
Disease(s): Pearson Syndrome
Assessment of Small Fiber Neuropathy in Rare Diseases Using Sudoscan
Status: Unknown status
Last Changed: Aug 16, 2018
First Received: Dec 07, 2016
Disease(s): Small Fiber Neuropathy, Fabry Disease, Ehlers Danlos Syndrome, Mitochondrial Disease
Intervention(s): Sudoscan, Skin biopsy, QSART
Locations: Massachusetts General Hospital, Boston, Massachusetts, United States
Heart Rate Variability in Response to Metformin Challenge
Status: Completed
Last Changed: Jan 03, 2018
First Received: Jul 16, 2015
Disease(s): Fibromyalgia, Mitochondrial Diseases, Movement Disorders, Diabetes Mellitus, Type 2
Intervention(s): Metformin
Locations: Woodinville Psychiatric Associates, Woodinville, Washington, United States
Natural History Study - Mitochondrial Disease
Status: Recruiting
Last Changed: Apr 17, 2020
First Received: Feb 15, 2012
Disease(s): MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
Locations: Columbia University, New York, New York, United States
Natural History and Advanced Genetic Study of Pyruvate Dehydrogenase Complex Deficiencies
Status: Recruiting
Last Changed: May 05, 2020
First Received: Feb 17, 2017
Disease(s): Pyruvate Dehydrogenase Complex Deficiency Disease
Intervention(s): No intervention
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
Abdominal Adiposity and Muscle Mitochondrial Functions
Status: Completed
Last Changed: Sep 19, 2012
First Received: Mar 13, 2007
Disease(s): Mitochondrial Respiratory Chain Deficiencies
Locations: Centre ed Recherche en Nutrition Humaine d'Auvergne (CRNH), Unité d'Exploration Nutritionnelle, Laboratoire de Nutrition humaine, Clermont Ferrand, France
Status: Recruiting
Last Changed: Sep 09, 2020
First Received: Nov 15, 2019
Disease(s): Mitochondrial Diseases, Mitochondrial Myopathies, Mitochondrial Encephalomyopathies, MELAS Syndrome, MIDD
Intervention(s): KH176, KH176, Placebo
Locations: Friedrich-Baur Institut, München, Bayern, Germany
Radboud University Medical Center, Nijmegen, Netherlands
Institute for Ageing and Health Newcastle University, Newcastle upon Tyne, United Kingdom