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Mitochondrial disorders

Mitochondrial genetic disordersMitochondrial diseases
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 211-220 of 243 results.
Phase 1 Trial of Idebenone to Treat Patients With Friedreich's Ataxia
Status: Completed
Last Changed: Mar 04, 2008
First Received: Mar 01, 2004
Disease(s): Friedreich Ataxia
Intervention(s): Idebenone
Locations: National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, United States
Transitional Life Events in Patients With Friedreich's Ataxia: Implications for Genetic Counseling
Status: Completed
Last Changed: Mar 04, 2008
First Received: Mar 07, 2003
Disease(s): Friedreich Ataxia
Locations: National Human Genome Research Institute (NHGRI), Bethesda, Maryland, United States
Safety Study of Idebenone to Treat Friedreich's Ataxia
Status: Completed
Last Changed: Jul 12, 2006
First Received: May 07, 2001
Disease(s): Friedreich Ataxia
Intervention(s): Idebenone
Locations: National Institute of Neurological Disorders and Stroke (NINDS), Bethesda, Maryland, United States
Efficacy Study of GS010 for the Treatment of Vision Loss up to 6 Months From Onset in LHON Due to the ND4 Mutation
Status: Completed
Last Changed: Jan 28, 2020
First Received: Jan 12, 2016
Disease(s): Optic, Atrophy, Hereditary, Leber
Intervention(s): GS010, Sham Intravitreal Injection
Locations: Doheny Eye Center, University of California, Los Angeles, Los Angeles, California, United States
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, United States
Neuro Ophthalmologic Associates, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Centre National Hospitalier d'Ophtalmologie des Quinze-VingtCentre National Hospitalier d'Ophtalmologie des Quinze-Vingt, Paris, France
Department of Neurology, University of Munich, Friedrich-Baur-Institute, Munich, Germany
... and 3 other locations.
Effect of a Wide Spectrum Nutritional Supplement on Mitochondrial Function in Children With Autism Spectrum Disorder
Status: Recruiting
Last Changed: Aug 24, 2020
First Received: Feb 08, 2019
Disease(s): Autism Spectrum Disorder
Intervention(s): Wide-spectrum nutritional supplement, Placebo
Locations: Phoenix Children's Hospital, Phoenix, Arizona, United States
Efficacy Study of GS010 for Treatment of Vision Loss From 7 Months to 1 Year From Onset in LHON Due to the ND4 Mutation (REVERSE)
Status: Completed
Last Changed: Jan 23, 2020
First Received: Jan 12, 2016
Disease(s): Optic, Atrophy, Hereditary, Leber
Intervention(s): GS010, Sham Intravitreal Injection
Locations: Doheny Eye Center, University of California, Los Angeles, Los Angeles, California, United States
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, United States
Neuro Ophthalmologic Associates, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, United States
Centre National Hospitalier d'Ophtalmologie des Quinze-Vingt, Paris, France
Department of Neurology, University of Munich, Friedrich-Baur-Institute, Munich, Germany
... and 3 other locations.
Mitochondrial Dysfunction, Inflammation, and White Matter Integrity in Youth With Mood Disorders
Status: Completed
Last Changed: Feb 05, 2020
First Received: Nov 04, 2015
Disease(s): Depression, Bipolar Disorder, Bipolar Disorder Not Otherwise Specified, Unspecified Mood Disorder
Locations: Ambulatory Research Center (ARC), Minneapolis, Minnesota, United States
Center for Magnetic Resonance Research, Minneapolis, Minnesota, United States
Mitochondrial Dysfunction in the Pathophysiology and Treatment of Bipolar Disorder
Status: Withdrawn
Last Changed: Nov 23, 2011
First Received: May 19, 2006
Disease(s): Bipolar Affective Disorder, Depression
Intervention(s): Coenzyme Q10
Locations: National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Mitochondrial Biomarkers in Huntington's Disease
Status: Recruiting
Last Changed: Aug 17, 2020
First Received: Aug 17, 2020
Disease(s): Huntington Disease
Intervention(s): lumbar puncture
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
A Study Into the Underlying Biochemical Pathways Involved in Parkinson's Disease, Such as Mitochondrial (Cellular "Powerhouse") Dysfunction
Status: Enrolling by invitation
Last Changed: Mar 26, 2020
First Received: Feb 05, 2018
Disease(s): Parkinson Disease, Parkinsonism
Locations: UCL Institute of Neurology, Department of Clinical Neurosciences, Upper 3rd Floor, Royal Free Hospital, Rowland Hill Street, London, United Kingdom