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Mitochondrial disorders

Mitochondrial genetic disordersMitochondrial diseases
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 171-180 of 243 results.
A First in Human Study of RT001 in Patients With Friedreich's Ataxia
Status: Completed
Last Changed: Oct 04, 2016
First Received: May 15, 2015
Disease(s): Friedreich's Ataxia
Intervention(s): RT001, RT001 comparator
Locations: Collaborative Neuroscience Network, LLC, Long Beach, California, United States
University of South Florida, Tampa, Florida, United States
Methylprednisolone Treatment of Friedreich Ataxia
Status: Completed
Last Changed: Oct 05, 2020
First Received: Apr 23, 2015
Disease(s): Friedreich Ataxia
Intervention(s): Methylprednisolone
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
RTA 408 Capsules in Patients With Friedreich's Ataxia - MOXIe
Status: Active, not recruiting
Last Changed: Oct 12, 2020
First Received: Oct 02, 2014
Disease(s): Friedreich Ataxia
Intervention(s): Omaveloxolone Capsules, 2.5 mg, Omaveloxolone Capsules, 5 mg, Omaveloxolone Capsules, 10 mg, Placebo, Omaveloxolone Capsules, 20 mg, Omaveloxolone Capsules, 40 mg, Omaveloxolone Capsules, 80 mg, Omaveloxolone Capsules, 160 mg, Omaveloxolone Capsules, 300 mg, Omaveloxolone Capsules, 150 mg
Locations: UCLA, Los Angeles, California, United States
University of Florida - Neurology, Gainesville, Florida, United States
USF Ataxia Research Center, Tampa, Florida, United States
Emory University Hospital - Neurology, Atlanta, Georgia, United States
University of Iowa Stead Family Children's Hospital, Iowa City, Iowa, United States
... and 7 other locations.
Safety, Tolerability and Efficacy of ACTIMMUNE® Dose Escalation in Friedreich's Ataxia
Status: Completed
Last Changed: Dec 08, 2017
First Received: Apr 14, 2015
Disease(s): Friedreich's Ataxia
Intervention(s): Interferon γ-1b, Placebo
Locations: University of California, Los Angeles Neurology Clinic, Los Angeles, California, United States
University of Florida - Clinical Research Center, Gainesville, Florida, United States
University of Iowa Children's Hospital, Iowa City, Iowa, United States
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)
Status: Recruiting
Last Changed: Sep 02, 2020
First Received: Dec 12, 2014
Disease(s): Friedreich's Ataxia
Intervention(s): Cardiac magnetic resonance imaging (CMR), Exercise-stress test, Echocardiogram (ECHO), Cardiac-related blood studies
Locations: Weill Cornell Medicine, New York, New York, United States
Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)
Status: Withdrawn
Last Changed: Aug 22, 2014
First Received: Dec 20, 2011
Disease(s): Leber's Hereditary Optic Neuropathy
Intervention(s): Idebenone, Placebo
MRI Study - Chronic Progressive External Ophthalmoplegia
Status: Completed
Last Changed: Apr 14, 2016
First Received: Jun 12, 2014
Disease(s): Chronic Progressive External Ophthalmoplegia
Intervention(s): Magnetic Resonance Imaging
Locations: Neuromuscular Research Unit, Copenhagen, Denmark
Preliminary Study of the Scale To Assess Ataxia and Neurologic Dysfunction (STAND)
Status: Completed
Last Changed: Jun 29, 2016
First Received: Jul 01, 2014
Disease(s): Spinocerebellar Ataxia - All Sub-types, Friedreich's Ataxia
Intervention(s): Ataxia rating scale
Locations: University of South Florida, Tampa, Florida, United States
RHODOS Follow-up Single-visit Study
Status: Completed
Last Changed: May 27, 2013
First Received: Aug 22, 2011
Disease(s): Leber's Hereditary Optic Neuropathy
Locations: Hôpital Notre-Dame (CHUM), Montreal,, Quebec, Canada
Friedrich Baur Institut Neurologische Klinik und Poliklinik, München, Germany
Biomedical Research Centre, The Medical School, Newcastle upon Tyne, United Kingdom
Near-infrared Light-emitting Diode (NIR-LED) Therapy for Leber's Hereditary Optic Neuropathy (LHON)
Status: Terminated
Last Changed: Sep 29, 2014
First Received: Jul 08, 2011
Disease(s): Leber's Hereditary Optic Neuropathy (LHON)
Intervention(s): Near-infrared light-emitting diode (NIR-LED) therapy (Med Light 630 PRO (Medical Devices Inc.))
Locations: Froedtert Memorial Lutheran Hospital, Milwaukee, Wisconsin, United States
Medical College of Wisconsin, Milwaukee, Wisconsin, United States
The Eye Institute, Milwaukee, Wisconsin, United States