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Mitochondrial disorders

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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 141-150 of 243 results.
New Non-invasive Modalities for Assessing Retinal Structure and Function
Status: Recruiting
Last Changed: May 09, 2019
First Received: Mar 23, 2018
Disease(s): Ischemic Optic Neuropathy, Branch Retinal Artery Occlusion, Hemianopia, Leber Hereditary Optic Neuropathy, Acute Zonal Occult Outer Retinopathy
Intervention(s): LSFG-NAVI
Locations: University of Iowa Department of Ophthalmology, Iowa City, Iowa, United States
Micronised Resveratrol as a Treatment for Friedreich Ataxia
Status: Recruiting
Last Changed: Sep 02, 2020
First Received: May 01, 2019
Disease(s): Friedreich Ataxia
Intervention(s): Resveratrol
Locations: Royal North Shore Hospital, St Leonards, New South Wales, Australia
University of Queensland Centre for Clinical Research, Herston, Queensland, Australia
Murdoch Children's Research Institute, Parkville, Victoria, Australia
Royal Perth Hospital, Perth, Western Australia, Australia
A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients
Status: Completed
Last Changed: Sep 25, 2020
First Received: Apr 17, 2019
Disease(s): Friedreich Ataxia
Intervention(s): MIN-102, Placebo
Locations: Hôpital Erasme-ULB, Brussels, Belgium
ICM, Groupe Hospitalier Pitié Salpêtrière, Paris, France
Universitätsklinikum RWTH, Aachen, Germany
Hospital Sant Joan de Déu, Barcelona, Spain
Hospital Universitario La Paz, Madrid, Spain
... and 1 other locations.
Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)
Status: Completed
Last Changed: Jan 30, 2020
First Received: Jun 10, 2016
Disease(s): Leber's Hereditary Optic Neuropathy (LHON)
Locations: CHU Saint-Pierre, Brussels, Belgium
Cliniques Universitaire Saint-Luc, Brussel, Belgium
Universitair Ziekenhuis Gent, Gent, Belgium
C. H. U. Sart Tilman, Liege, Belgium
CHU Angers - Hôpital Hôtel Dieu, Angers, France
... and 17 other locations.
Relationship Between Neurological Disability and Visual Impairment in Patients With ALS or Friedreich's Ataxia
Status: Unknown status
Last Changed: Feb 26, 2019
First Received: Sep 15, 2017
Disease(s): Amyotrophic Lateral Sclerosis
Locations: Pilar Rojas Lozano, Madrid, Spain
Open Trail of γIFN for Friedreich Ataxia
Status: Completed
Last Changed: Feb 26, 2020
First Received: Mar 25, 2019
Disease(s): Friedreich Ataxia
Intervention(s): gamma interferon
Study to Assess the Efficacy and Safety of Raxone in LHON Patients
Status: Active, not recruiting
Last Changed: Jun 17, 2019
First Received: May 16, 2016
Disease(s): Leber's Hereditary Optic Neuropathy (LHON)
Intervention(s): Idebenone
Locations: Retinal Consultants of Arizona, Phoenix, Arizona, United States
Palo Alto Medical Foundation, Palo Alto, California, United States
Stanford Byers Eye Institute, Stanford, California, United States
University of Colorado Health Eye Center, Aurora, Colorado, United States
Emory University Hospital, Atlanta, Georgia, United States
... and 25 other locations.
Post Authorisation Safety Study With Raxone in LHON Patients
Status: Active, not recruiting
Last Changed: Aug 11, 2020
First Received: May 13, 2016
Disease(s): Leber's Hereditary Optic Neuropathy (LHON)
Intervention(s): Idebenone
Locations: Universitaetsklinikum Graz, Graz, Austria
Medical University of Vienna, Vienna, Austria
CHU de Nîmes - Hôpital Carémeau, Nîmes, Gard, France
CHU Angers - Hôpital Hôtel Dieu, Angers, Maine Et Loire, France
Hopital Roger Salengro - CHU Lille, Lille, Nord, France
... and 22 other locations.
Trial of Dichloroacetate in Pyruvate Dehydrogenase Complex Deficiency:
Status: Recruiting
Last Changed: Oct 19, 2020
First Received: Nov 30, 2015
Disease(s): Pyruvate Dehydrogenase Complex Deficiency
Intervention(s): Dichloroacetate (DCA), Placebo, Genotype
Locations: Children's Hospital of Orange County, Orange, California, United States
Stanford University, Stanford, California, United States
Children's National Medical Center, Washington, District of Columbia, United States
University of Florida, Gainesville, Florida, United States
University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States
... and 5 other locations.
A Study Investigating the Safety, Tolerability, and Efficacy of Elamipretide (MTP-131) Topical Ophthalmic Solution for the Treatment of Leber's Hereditary Optic Neuropathy
Status: Completed
Last Changed: Jan 28, 2020
First Received: Feb 26, 2016
Disease(s): Leber's Hereditary Optic Neuropathy
Intervention(s): elamipretide (MTP-131) 1% topical ophthalmic solution, Vehicle topical ophthalmic solution
Locations: Doheny Eye Center, Pasadena, California, United States