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Mitochondrial disorders

Mitochondrial genetic disordersMitochondrial diseases
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 91-100 of 239 results.
Niacin Supplementation in Healthy Controls and Mitochondrial Myopathy Patients
Status: Completed
Last Changed: Jun 04, 2019
First Received: Jun 04, 2019
Disease(s): Mitochondrial Myopathies
Intervention(s): Niacin
A Study of the Safety of REN001 in Patients With Primary Mitochondrial Myopathy
Status: Terminated
Last Changed: Jul 16, 2020
First Received: Mar 05, 2019
Disease(s): Primary Mitochondrial Myopathy
Intervention(s): REN001
Locations: Institute of Neurology, University College London, London, United Kingdom
Wellcome Centre for Mitochondrial Research, Newcastle Upon Tyne, United Kingdom
Diagnostic Screening Tests and Potential Biomarkers in Mitochondrial Myopathies
Status: Unknown status
Last Changed: May 02, 2018
First Received: May 02, 2018
Disease(s): Mitochondrial Myopathies
Intervention(s): Diagnostic screenings tests
Locations: Copenhagen Neuromuscular Center, Rigshospitalet, Copenhagen, Denmark
Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy
Status: Completed
Last Changed: Jun 24, 2005
First Received: Feb 25, 2000
Disease(s): Mitochondrial Myopathy
Intervention(s): thioctic acid
RTA 408 Capsules in Patients With Mitochondrial Myopathy - MOTOR
Status: Completed
Last Changed: Sep 17, 2020
First Received: Oct 02, 2014
Disease(s): MItochondrial Myopathies
Intervention(s): Omaveloxolone capsules, 2.5 mg, omaveloxolone capsules, 5 mg, omaveloxolone capsules, 10 mg, Placebo capsules, omaveloxolone capsules, 20 mg, omaveloxolone capsules, 40 mg, omaveloxolone capsules, 80 mg, omaveloxolone capsules, 160 mg
Locations: UCLA, Los Angeles, California, United States
Mass General Hospital, Boston, Massachusetts, United States
Akron Children's Hospital, Akron, Ohio, United States
The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
University of Pittsburgh, Pittsburgh, Pennsylvania, United States
... and 5 other locations.
RESCUE and REVERSE Long-term Follow-up
Status: Active, not recruiting
Last Changed: Jul 23, 2020
First Received: Jan 23, 2018
Disease(s): Leber Hereditary Optic Neuropathy
Intervention(s): GS010, Sham
Locations: Doheny Eye Center UCLA, Pasadena, California, United States
Emory University Hospital, Atlanta, Georgia, United States
Wills Eye Institute, Philadelphia, Pennsylvania, United States
CHNO Les Quinze Vingts, Paris, France
LMU Klinikum der Universität München / Friedrich-Baur-Institut, Munich, Germany
... and 3 other locations.
EAP_GS010_single Patient
Status: Available
Last Changed: Feb 25, 2019
First Received: Sep 17, 2018
Disease(s): Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
Intervention(s): GS010
REALITY LHON Registry
Status: Completed
Last Changed: Jul 23, 2020
First Received: Sep 27, 2017
Disease(s): Leber Hereditary Optic Neuropathy
Intervention(s): Patient-reported outcomes (PROs)
Locations: Doheny Eye Center UCLA Pasadena, Pasadena, California, United States
Emory University Hospital, Atlanta, Georgia, United States
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States
Wills Eye Institute, Philadelphia, Pennsylvania, United States
Alkek Eye Center, Houston, Texas, United States
... and 7 other locations.
Efficacy & Safety Study of Bilateral IVT Injection of GS010 in LHON Subjects Due to the ND4 Mutation for up to 1 Year
Status: Active, not recruiting
Last Changed: Jul 23, 2020
First Received: Sep 26, 2017
Disease(s): Leber Hereditary Optic Neuropathy
Intervention(s): GS010, Placebo
Locations: Doheny Eye Center UCLA Pasadena, Pasadena, California, United States
University of Colorado Health Eye Center, Aurora, Colorado, United States
Emory Healthcare - The Emory Clinic, Atlanta, Georgia, United States
Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States
Icahn School of Medicine at Mount Sinai, New York, New York, United States
... and 9 other locations.
Effect Of The System In The Enriched Fat Metabolism Of The Child Reached Mitochondrial Cytopathy
Status: Completed
Last Changed: Mar 11, 2015
First Received: Mar 11, 2015
Disease(s): Mitochondrial Cytopathies Disorders
Intervention(s): high fat diet, normal fat diet
Locations: Centre d'Investigation Clinique, Lille, France
Centre d'Investigation Clinique, Paris, France