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Synovial sarcoma

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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 25 results.
DHEA in Synovial Sarcoma Patients
Status: Recruiting
Last Changed: Sep 07, 2018
First Received: Feb 17, 2016
Disease(s): Synovial Sarcoma, Sarcoma, Synovial
Intervention(s): DHEA, FACT-67 validated survey
Locations: Washington University School of Medicine, Saint Louis, Missouri, United States
A Phase III Trial of Anlotinib in Metastatic or Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma and Synovial Sarcoma
Status: Recruiting
Last Changed: Apr 05, 2019
First Received: Jan 11, 2017
Disease(s): Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma, Soft-Tissue Sarcoma
Intervention(s): AL 3818, Dacarbazine
Locations: University of California Los Angeles, Los Angeles, California, United States
Sarcoma Oncology Center, Santa Monica, California, United States
Stanford Medicine Cancer Institute, Stanford, California, United States
University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States
University of Michigan Comprehensive Cancer Center, Ann Arbor, Michigan, United States
... and 7 other locations.
A Phase 1 Study of the EZH2 Inhibitor Tazemetostat in Pediatric Subjects With Relapsed or Refractory INI1-Negative Tumors or Synovial Sarcoma
Status: Recruiting
Last Changed: Jun 19, 2019
First Received: Nov 11, 2015
Disease(s): Rhabdoid Tumors, INI1-negative Tumors, Synovial Sarcoma, Malignant Rhabdoid Tumor of Ovary
Intervention(s): Tazemetostat
Locations: Children's Hospital of Los Angeles, Los Angeles, California, United States
University of California San Francisco - Benioff Children's Hospital, San Francisco, California, United States
Children's Hospital Colorado, Aurora, Colorado, United States
Children's National Medical Center, Washington, District of Columbia, United States
Children's Healthcare of Atlanta, Atlanta, Georgia, United States
... and 29 other locations.
Study of a Cohort of Cases of Synovial Sarcoma Treated in the Orthopedic Surgery and Traumatology Department of the Hospital de Sant Pau Between 1983 and 2016
Status: Recruiting
Last Changed: Feb 08, 2019
First Received: Feb 06, 2019
Disease(s): Soft Tissue Sarcoma Adult
Intervention(s): Soft tissue sarcomas in adults
Locations: Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
A Phase II, Multicenter Study of the EZH2 Inhibitor Tazemetostat in Adult Subjects With INI1-Negative Tumors or Relapsed/Refractory Synovial Sarcoma
Status: Recruiting
Last Changed: Jun 19, 2019
First Received: Nov 11, 2015
Disease(s): Malignant Rhabdoid Tumors (MRT), Rhabdoid Tumors of the Kidney (RTK), Atypical Teratoid Rhabdoid Tumors (ATRT), Selected Tumors With Rhabdoid Features, Synovial Sarcoma, INI1-negative Tumors, Malignant Rhabdoid Tumor of Ovary, Renal Medullary Carcinoma, Epithelioid Sarcoma, Poorly Differentiated Chordoma (or Other Chordoma With Sponsor Approval), Any Solid Tumor With an EZH2 GOF Mutation
Intervention(s): Tazemetostat
Locations: University of California San Francisco, San Francisco, California, United States
University of Colorado Denver, Aurora, Colorado, United States
Mayo Clinic - Jacksonville, Jacksonville, Florida, United States
Northwestern Memorial Hospital, Chicago, Illinois, United States
Massachusetts General Hospital - Cancer Center, Boston, Massachusetts, United States
... and 28 other locations.
Pembrolizumab and Interferon Gamma-1b in Treating Patients With Stage IB-IVB Relapsed or Refractory Mycosis Fungoides and Sezary Syndrome
Status: Recruiting
Last Changed: Jun 18, 2019
First Received: Feb 24, 2017
Disease(s): Metastatic Myxoid Liposarcoma, Metastatic Round Cell Liposarcoma, Metastatic Synovial Sarcoma, NY-ESO-1 Positive Tumor Cells Present, Recurrent Mycosis Fungoides and Sezary Syndrome, Refractory Mycosis Fungoides and Sezary Syndrome, Stage IB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage II Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage III Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIIA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IIIB Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IV Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IVA Mycosis Fungoides and Sezary Syndrome AJCC v7, Stage IVB Mycosis Fungoides and Sezary Syndrome AJCC v7, Unresectable Synovial Sarcoma
Intervention(s): Interferon Gamma-1b, Laboratory Biomarker Analysis, Pembrolizumab
Locations: Stanford Cancer Institute Palo Alto, Palo Alto, California, United States
University of Miami Miller School of Medicine-Sylvester Cancer Center, Miami, Florida, United States
Dana-Farber Cancer Institute, Boston, Massachusetts, United States
Washington University School of Medicine, Saint Louis, Missouri, United States
Memorial Sloan Kettering Cancer Center, New York, New York, United States
... and 2 other locations.
Detection of Circulating Tumor Cells in Patients With Sarcomas
Status: Recruiting
Last Changed: Jul 02, 2018
First Received: Dec 06, 2016
Disease(s): Leiomyosarcoma, Pleomorphic Liposarcoma, Synovial Sarcoma, Liposarcoma
Locations: ACCamargo Cancer Center, Sao Paulo, SP, Brazil
NY-ESO-1-redirected CRISPR (TCRendo and PD1) Edited T Cells (NYCE T Cells)
Status: Recruiting
Last Changed: Mar 04, 2019
First Received: Jan 16, 2018
Disease(s): Multiple Myeloma, Melanoma, Synovial Sarcoma, Myxoid/Round Cell Liposarcoma
Intervention(s): NY-ESO-1 redirected autologous T cells with CRISPR edited endogenous TCR and PD-1, Cyclophosphamide, Fludarabine, NY-ESO-1 expression testing
Locations: University of Pennsylvania, Philadelphia, Pennsylvania, United States
Safety and Efficacy of IMCnyeso in Advanced NY-ESO-1 and/or LAGE-1A Positive Cancers
Status: Recruiting
Last Changed: Jun 04, 2019
First Received: May 03, 2018
Disease(s): Melanoma, Advanced NSCLC, Urothelial Carcinoma, Synovial Sarcoma
Intervention(s): IMCnyeso, IMCnyeso
Locations: University of Michigan Comprehensive Cancer Center, Detroit, Michigan, United States
Washington University School of Medicine in St. Louis, Saint Louis, Missouri, United States
Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, United States
Hillman Cancer Center, Pittsburgh, Pennsylvania, United States
MD Anderson Cancer Center, Houston, Texas, United States
... and 4 other locations.
Itacitinib in Treating Participants With Refractory Metastatic/Advanced Soft Tissue Sarcomas
Status: Not yet recruiting
Last Changed: May 16, 2019
First Received: Sep 13, 2018
Disease(s): Metastatic Leiomyosarcoma, Metastatic Synovial Sarcoma, Metastatic Undifferentiated Pleomorphic Sarcoma, Round Cell Liposarcoma
Intervention(s): Itacitinib, Laboratory Biomarker Analysis
Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington, United States