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Mitochondrial disorders

Mitochondrial genetic disordersMitochondrial diseases
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-10 of 68 results.
Clinical Study of Extra-virgin Olive Oil in Mitochondrial Diseases
Status: Not yet recruiting
Last Changed: Sep 10, 2020
First Received: Sep 10, 2020
Disease(s): Mitochondrial Diseases
Intervention(s): Extra-virgin olive oil (EVOO) intake, Extra-virgin olive oil (EVOO) intake and withdraw
A First in Human Study to Evaluate the Safety of Infusion of MNV-BM-PLC (Autologous CD34+ Cells Enriched With Placenta Derived Allogeneic Mitochondria) in Patients With Primary Mitochondrial Diseases Associated With Mitochondrial DNA Mutation or Deletion
Status: Not yet recruiting
Last Changed: Sep 15, 2020
First Received: Sep 15, 2020
Disease(s): Primary Mitochondrial Diseases
Intervention(s): Bone Marrow mobilization, Apheresis, MNV-BM-PLC infusion
Locations: Sheba Medical Center - Tel Ashomer, Ramat Gan, Israel
Identification of New Candidate Genes in Patients With Mitochondrial Disease by High Resolution Chromosome Analysis on DNA Chip
Status: Recruiting
Last Changed: Sep 04, 2020
First Received: Feb 28, 2019
Disease(s): Mitochondrial Diseases
Locations: Nice hospital, Nice, France
Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity During the COVID19 Pandemic
Status: Recruiting
Last Changed: Sep 25, 2020
First Received: Jun 09, 2020
Disease(s): Mitochondrial Disease
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland, United States
A Study to Evaluate Efficacy and Safety of Vatiquinone for Treating Mitochondrial Disease in Participants With Refractory Epilepsy
Status: Not yet recruiting
Last Changed: Jun 19, 2020
First Received: May 07, 2020
Disease(s): Mitochondrial Diseases, Drug Resistant Epilepsy
Intervention(s): Vatiquinone, Placebo
Anesthesia in Patients With Mitochondrial Disease
Status: Recruiting
Last Changed: Dec 03, 2018
First Received: Feb 04, 2014
Disease(s): Mitochondrial Diseases
Intervention(s): Sevoflurane, Dexmedetomidine, Propofol
Locations: University of Texas Health Science Center at Houston, Houston, Texas, United States
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
Status: Recruiting
Last Changed: Aug 05, 2019
First Received: Sep 27, 2012
Disease(s): Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
Locations: University of California San Diego, San Diego, California, United States
Lucile Packard Children's Hospital, Stanford, California, United States
Children's Hospital of Colorado, Aurora, Colorado, United States
Children's National Medical Center, Washington, District of Columbia, United States
University of Florida, Gainesville, Florida, United States
... and 13 other locations.
Impact of Statin Therapy on Muscle Mitochondrial Function and Aerobic Capacity
Status: Recruiting
Last Changed: Nov 06, 2019
First Received: Nov 24, 2017
Disease(s): Mitochondrial Diseases
Intervention(s): Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Placebo Oral Tablet
Locations: University of Kansas Medical Center, Kansas City, Kansas, United States
East Carolina University, Greenville, North Carolina, United States
Mitochondrial Donation: An 18 Month Outcome Study.
Status: Recruiting
Last Changed: Oct 02, 2019
First Received: Oct 02, 2019
Disease(s): Mitochondrial Diseases
Intervention(s): observational
Locations: The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, Tyne & Wear, United Kingdom
A Phase Ia/Ib, SAD and MAD Study of of KL1333 in Healthy Subjects and Patients With Primary Mitochondrial Disease
Status: Recruiting
Last Changed: Mar 25, 2019
First Received: Mar 25, 2019
Disease(s): Mitochondrial Diseases, Mitochondrial Respiratory Chain Deficiencies, MELAS Syndrome, Mitochondrial Myopathies
Intervention(s): KL1333, Placebo Oral Tablet
Locations: Covance Leeds, Leeds, West Yorkshire, United Kingdom