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Demyelinating Diseases

Hypomyelination
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 31-40 of 541 results.
Lentiviral Gene Therapy for MLD
Status: Recruiting
Last Changed: Sep 19, 2019
First Received: Oct 31, 2018
Disease(s): Metachromatic Leukodystrophy (MLD)
Intervention(s): Lentivirus-mediated delivery of ARSA to the CNS.
Locations: Lung-Ji Chang, Shenzhen, Guangdong, China
Longitudinal Natural History Study of Patients With Peroxisome Biogenesis Disorders (PBD)
Status: Recruiting
Last Changed: Feb 28, 2020
First Received: Aug 17, 2012
Disease(s): Peroxisome Biogenesis Disorders, D-Bifunctional Protein Deficiency, X-linked Adrenoleukodystrophy, Alpha-Methylacyl-CoA Racemase Deficiency, Peroxisomal Acyl-CoA Oxidase Deficiency, Adult Refsum's Disease
Locations: Research Institute of the McGill University Health Center, Montreal, Quebec, Canada
Autologous Hematopoietic Stem Cell Gene Therapy for Metachromatic Leukodystrophy and Adrenoleukodystrophy
Status: Recruiting
Last Changed: Sep 24, 2015
First Received: Sep 24, 2015
Disease(s): Metachromatic Leukodystrophy, Adrenoleukodystrophy
Intervention(s): transduced CD34+ hematopoietic stem cell
Locations: Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China
Adrenoleukodystrophy National Registry Study
Status: Recruiting
Last Changed: Jul 01, 2020
First Received: Dec 31, 2018
Disease(s): ALD (Adrenoleukodystrophy), Adrenoleukodystrophy, Cerebral Adrenoleukodystrophy
Intervention(s): Medical Record Abstraction, Biospecimen Sample Collection
Locations: Masonic Cancer Center at University of Minnesota, Minneapolis, Minnesota, United States
Lentiviral Gene Therapy for X-ALD
Status: Recruiting
Last Changed: Sep 19, 2019
First Received: Nov 01, 2018
Disease(s): X-linked Adrenoleukodystrophy
Intervention(s): Intracerebral LV gene therapy
Locations: Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
Autologous Stem/Stromal Cells in Neurological Disorders and Disease
Status: Not yet recruiting
Last Changed: Oct 18, 2018
First Received: Sep 29, 2017
Disease(s): Dementia, Parkinson, Altered Behavior in Alzheimer Disease, Demyelinating Autoimmune Diseases, CNS, Demyelinating Sensorimotor Neuropathy, Corticobasal Degeneration
Intervention(s): Microcannula Harvest Adipose, Centricyte 1000, Sterile Normal Saline Infusion
Locations: Regeneris Medical Inc, North Attleboro, Massachusetts, United States
Regeneris Medical, North Attleboro, Massachusetts, United States
Early Detection and Paramedical Care of Sexual Difficulties in Nervous System Diseases: Example of Multiple Sclerosis and Brain Tumors (NEUROSEX)
Status: Recruiting
Last Changed: Jan 21, 2020
First Received: May 16, 2017
Disease(s): Low Grade Glioma of Brain, Multiple Sclerosis, Sexual Dysfunctions
Intervention(s): Paramedical care
Locations: Groupe Hospitalier Pitie Salpetriere, Paris, France
Regulation of Lipid Metabolism in Autoimmune Disease: Multiple Sclerosis
Status: Recruiting
Last Changed: Apr 24, 2020
First Received: Aug 12, 2019
Disease(s): Multiple Sclerosis
Intervention(s): Blood sampling
Locations: University College London Hospitals NHS Foundation Trust, London, United Kingdom
National Hospital for Neurology and Neurosurgery, London, United Kingdom
A Clinical Study in Male Pediatric Patients With Cerebral X-linked Adrenoleukodystrophy (Cald) to Assess the Effects of MIN-102 Treatment on Disease Progression Prior to Human Stem Cell Transplant (HSCT)
Status: Recruiting
Last Changed: Aug 27, 2020
First Received: Aug 27, 2020
Disease(s): Cerebral Adrenoleukodystrophy
Intervention(s): MIN-102
Locations: CHU Kremlin Bicêtre, Paris, France
Universitätsmedizin Göttingen Georg-August-Universität, Göttingen, Germany
Universitätsklinikum Hamburg-Eppendorf Klinik und Poliklinik für Kinder- und Jugendmedizin, Hamburg, Germany
Hospital Sant Joan de Déu, Barcelona, Spain
A Study to Prospectively Assess Disease Progression in Male Children With X-ALD
Status: Recruiting
Last Changed: Aug 08, 2018
First Received: Sep 12, 2017
Disease(s): X-Linked Adrenoleukodystrophy
Locations: Stanford University, Palo Alto, California, United States
Massachusetts General Hospital, Boston, Massachusetts, United States
University of Pittsburgh, Pittsburgh, Pennsylvania, United States