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Adenosine Deaminase Deficiency

Severe combined immunodeficiency due to ADA deficiency
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Clinical Trials

This information is provided by ClinicalTrials.gov

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Displaying 1-8 of 8 results.
Registry Study of Revcovi Treatment in Patients With ADA-SCID
Status: Recruiting
Last Changed: Nov 19, 2019
First Received: Mar 18, 2019
Disease(s): Adenosine Deaminase Deficiency, Severe Combined Immunodeficiency
Intervention(s): elapegademase-lvlr
Locations: University of California Los Angeles, Los Angeles, California, United States
UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
Le Bonheur Children's Hospital, Memphis, Tennessee, United States
Gene Transfer for ADA-SCID Using an Improved Lentiviral Vector (TYF-ADA)
Status: Recruiting
Last Changed: Sep 20, 2019
First Received: Aug 24, 2018
Disease(s): Adenosine DeAminase Severe Combined ImmunoDeficiency (ADA-SCID)
Intervention(s): TYF-ADA gene-modified autologous stem cells
Locations: Shenzhen Geno-immune Medical Institute, Shenzhen, Guangdong, China
A Clinical Study to Enable Process Validation of Commercial Grade OTL-101
Status: Recruiting
Last Changed: Oct 28, 2019
First Received: Oct 28, 2019
Disease(s): Severe Combined Immunodeficiency Due to ADA Deficiency
Intervention(s): OTL-101
Locations: University of California, Los Angeles, Los Angeles, California, United States
Gene Therapy for Patients With ADA Adenosine Deaminase (ADA) Deficiency
Status: Recruiting
Last Changed: Dec 06, 2018
First Received: Dec 05, 2018
Disease(s): Ada-Scid
Intervention(s): Lentiviral transduced CD34+ cells
Locations: Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
Evaluating the Effectiveness of STRIMVELIS Risk Minimization Measures (RMMs)
Status: Recruiting
Last Changed: May 15, 2019
First Received: Jul 27, 2017
Disease(s): Severe Combined Immunodeficiency Due to ADA Deficiency
Intervention(s): STRIMVELIS
Locations: Ospedale San Raffaele - Telethon Institute for Gene Therapy (OSR-TIGET), Milan, Italy
Patients Treated for SCID (1968-Present)
Status: Recruiting
Last Changed: Nov 21, 2018
First Received: May 02, 2011
Disease(s): SCID, ADA-SCID, XSCID, Leaky SCID, Omenn Syndrome, Reticular Dysgenesis
Locations: University of Alabama at Birmingham, Birmingham, Alabama, United States
Children's Hospital Los Angeles, Los Angeles, California, United States
University of California, Los Angeles, Los Angeles, California, United States
Lucile Salter Packard Children's Hospital at Stanford, Palo Alto, California, United States
University of California San Francisco Children's Hospital, San Francisco, California, United States
... and 32 other locations.
Natural History Study of SCID Disorders
Status: Recruiting
Last Changed: Sep 18, 2019
First Received: Aug 23, 2010
Disease(s): Severe Combined Immunodeficiency (SCID), Leaky SCID, Omenn Syndrome, Reticular Dysgenesis, ADA SCID, XSCID
Locations: University of Alabama at Birmingham, Birmingham, Alabama, United States
Phoenix Children's Hospital, Phoenix, Arizona, United States
Children's Hospital Los Angeles, Los Angeles, California, United States
University of California, Los Angeles, Los Angeles, California, United States
Lucile Salter Packard Children's Hospital at Stanford, Palo Alto, California, United States
... and 40 other locations.
Retroviral Insertion Site Methodology Study
Status: Not yet recruiting
Last Changed: Oct 30, 2019
First Received: Oct 16, 2017
Disease(s): Immune System Diseases
Intervention(s): Strimvelis