Burkitt's Lymphoma

Common Name(s)

Burkitt's Lymphoma

Burkitt lymphoma is a rare, aggressive B-cell lymphoma that accounts for 30 to 50% of lymphomas in children but only 1 to 2% of lymphomas in adults ({10:Harris and Horning, 2006}). It results from chromosomal translocations that involve the MYC gene ({190080}) and either the lambda or the kappa light chain immunoglobulin genes ({147220}, {147200}). Burkitt lymphoma is causally related to the Epstein-Barr virus (EBV), although the pathogenetic mechanisms are not clear.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Burkitt's Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

Last Updated: 20 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Burkitt's Lymphoma" for support, advocacy or research.

National Bone Marrow Transplant Link

The mission of the National Bone Marrow Transplant Link is to help patients, caregivers, and families cope with the social and emotional challenges of bone marrow/stem cell transplant from diagnosis through survivorship by providing vital information and personalized support services.

http://www.nbmtlink.org

Last Updated: 20 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Burkitt's Lymphoma" returned 460 free, full-text research articles on human participants. First 3 results:

Burkitt's lymphoma of the humerus.
 

Author(s): N Geetha, K P Sreelesh, Rekha A Nair, Priya Mary Jacob

Journal: J Cancer Res Ther. ;11(4):1025.

 

Burkitt's lymphoma is an uncommon form of non-Hodgkin's lymphoma (NHL) in adults and represents < 5% of NHL adults. Burkitt's lymphoma involving primarily the appendicular skeleton is rarely described. We present the case of a young man with primary Burkitt's lymphoma involving the ...

Last Updated: 17 Feb 2016

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Burkitt's Lymphoma of the Rectosigmoid and Stomach Presenting as Hematochezia.
 

Author(s): Marco Bustamante-Bernal, Juan Galvis, Dubier Matos, Omar Sosa, Saad H Syed, Osvaldo Padilla, Brian Davis, Marc J Zuckerman

Journal:

 

Burkitt's lymphoma (BL) is an uncommon cause of non-Hodgkin lymphoma in adults and accounts for only 0.1-0.5% of all malignant tumors of the colon and rectum. Very few cases of rectosigmoid and stomach BL have been reported in adults.

Last Updated: 15 Feb 2016

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MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt's Lymphoma Cells to Trigger Apoptosis through Multiple Pathways.
 

Author(s): Imtiaj Hasan, Shigeki Sugawara, Yuki Fujii, Yasuhiro Koide, Daiki Terada, Naoya Iimura, Toshiyuki Fujiwara, Keisuke G Takahashi, Nobuhiko Kojima, Sultana Rajia, Sarkar M A Kawsar, Robert A Kanaly, Hideho Uchiyama, Masahiro Hosono, Yukiko Ogawa, Hideaki Fujita, Jiharu Hamako, Taei Matsui, Yasuhiro Ozeki

Journal:

 

MytiLec; a novel lectin isolated from the Mediterranean mussel (Mytilus galloprovincialis); shows strong binding affinity to globotriose (Gb3: Galα1-4Galβ1-4Glc). MytiLec revealed β-trefoil folding as also found in the ricin B-subunit type (R-type) lectin family, although the amino ...

Last Updated: 23 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Burkitt's Lymphoma" returned 18 free, full-text review articles on human participants. First 3 results:

The Link between Plasmodium falciparum Malaria and Endemic Burkitt's Lymphoma-New Insight into a 50-Year-Old Enigma.
 

Author(s): David Thorley-Lawson, Kirk W Deitsch, Karen A Duca, Charles Torgbor

Journal:

 

Last Updated: 22 Jan 2016

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Burkitt's lymphoma developing post liver transplantation: posttransplant lymphoproliferative disorders international survey.
 

Author(s): Hossein Khedmat, Mohammad Ebrahim Ghamar-Chehreh, Mohsen Amini, Saeed Taheri

Journal: Saudi J Kidney Dis Transpl. 2014 Nov;25(6):1290-2.

 

Last Updated: 14 Nov 2014

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Burkitt's lymphoma masquerading as appendicitis--two case reports and review of the literature.
 

Author(s): Elroy P Weledji, Marcelin N Ngowe, John S Abba

Journal:

 

Two cases of Burkitt's lymphoma masquerading as appendicitis are reported herein. The diagnoses were made post-operatively from the appendix specimen in one case and from an ileocecal resection specimen for cecal fistula complicating an appendicectomy in the second case. These cases ...

Last Updated: 1 Jul 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Safety and Efficacy of CART-19 Cells in B-cell Acute Lymphoblastic Leukemia (B-ALL).
 

Status: Recruiting

Condition Summary: B-cell Acute Lymphoblastic Leukemia

 

Last Updated: 4 Oct 2016

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Last Updated: 8 Aug 2016

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Epidemiology of Burkitt Lymphoma in East Africa Children or Minors (EMBLEM)
 

Status: Recruiting

Condition Summary: Lymphoma, Non-Hodgkin; Malaria; Herpesvirus 4, Human

 

Last Updated: 1 Dec 2016

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