Bullous Pemphigoid

Common Name(s)

Bullous Pemphigoid

Bullous pemphigoid is a skin disorder characterized by large blisters. The blisters are usually located on the arms, legs, or middle of the body. About one-third of persons with bullous pemphigoid also develop blisters in the mouth. The blisters may break open and form ulcers or open sores. It usually occurs in elderly persons and is rare in young people. Symptoms come and go. In most patients, the condition goes away within 6 years. The cause is not known, but may be related to immune system disorders.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bullous Pemphigoid" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bullous Pemphigoid" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bullous Pemphigoid" returned 341 free, full-text research articles on human participants. First 3 results:

A randomised controlled trial to compare the safety, effectiveness and cost-effectiveness of doxycycline (200 mg/day) with that of oral prednisolone (0.5 mg/kg/day) for initial treatment of bullous pemphigoid: the Bullous Pemphigoid Steroids and Tetracyclines (BLISTER) trial.
 

Author(s): Joanne R Chalmers, Fenella Wojnarowska, Gudula Kirtschig, James Mason, Margaret Childs, Diane Whitham, Karen Harman, Anna Chapman, Shernaz Walton, Enno Schmidt, Thomas R Godec, Andrew J Nunn, Hywel C Williams

Journal: Health Technol Assess. 2017 Mar;21(10):1-90.

 

Bullous pemphigoid (BP) is an autoimmune blistering skin disorder with increased morbidity and mortality in the elderly.

Last Updated: 31 Dec 1969

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Systemic Lupus Erythematosus and Bullous Pemphigoid with Dramatic Response to Dapsone.
 

Author(s): Maria Cristina Maggio, Giovanni Corsello, Eugenia Prinzi, Rolando Cimaz

Journal:

 

BACKGROUND Bullous pemphigoid is an autoimmune blistering disease, with relapses, isolated or associated with other autoimmune diseases such as systemic lupus erythematosus (SLE). Joint manifestations rapidly respond to small or moderate doses of corticosteroids, whereas skin manifestations ...

Last Updated: 31 Dec 1969

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Increased Activity and Apoptosis of Eosinophils in Blister Fluids, Skin and Peripheral Blood of Patients with Bullous Pemphigoid.
 

Author(s): Judith Engmann, Urda Rüdrich, Georg Behrens, Eleni Papakonstantinou, Manuela Gehring, Alexander Kapp, Ulrike Raap

Journal: Acta Derm. Venereol.. 2017 Apr;97(4):464-471.

 

Bullous pemphigoid (BP) is an autoimmune blistering skin disease that is more common in elderly individuals. The aim of this study was to determine the functional activity of eosinophils in patients with BP compared with healthy donors. Blood, skin and blister-derived eosinophils ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bullous Pemphigoid" returned 18 free, full-text review articles on human participants. First 3 results:

Mechanisms of Disease: Pemphigus and Bullous Pemphigoid.
 

Author(s): Christoph M Hammers, John R Stanley

Journal: Annu Rev Pathol. 2016 May;11():175-97.

 

Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and in pemphigoid, the basal keratinocytes lose adhesion to the basement membrane. Pemphigus lesions are mediated ...

Last Updated: 31 Dec 1969

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Three Cases of Bullous Pemphigoid Associated with Dipeptidyl Peptidase-4 Inhibitors - One due to Linagliptin.
 

Author(s): Francisco Manuel Ildefonso Mendonça, Francisco José Martín-Gutierrez, Juan José Ríos-Martín, Francisco Camacho-Martinez

Journal: Dermatology (Basel). 2016 ;232(2):249-53.

 

Bullous pemphigoid (BP) is an acquired subepidermal autoimmune blistering disease in which there are humoral and cellular responses against the BP180 and BP230 antigens. Dipeptidyl peptidase (DPP)-4 inhibitors enhance endogenous glucagon peptide-1 and glucose-dependent insulinotropic ...

Last Updated: 31 Dec 1969

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Erythematous Variety of Bullous Pemphigoid: Case Report and Literature Review.
 

Author(s): Yukari Ise, Yasushi Suga, Kazuko Okumura, Osamu Negi, Norito Ishii, Takashi Hashimoto

Journal: Acta Derm. Venereol.. 2016 Mar;96(3):412-3.

 

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Clinical Characteristics of Pruritus and Evaluation of Quality of Life in Patients With Bullous Pemphigoid
 

Status: Not yet recruiting

Condition Summary: Bullous Pemphigoid

 

Last Updated: 3 Sep 2017

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A Proof-of-Concept Study of Topical AC-203 in Patients With Bullous Pemphigoid
 

Status: Recruiting

Condition Summary: Bullous Pemphigoid

 

Last Updated: 18 Sep 2017

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Last Updated: 15 Jul 2016

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