Bullous Pemphigoid

Common Name(s)

Bullous Pemphigoid

Bullous pemphigoid is a skin disorder characterized by large blisters. The blisters are usually located on the arms, legs, or middle of the body. About one-third of persons with bullous pemphigoid also develop blisters in the mouth. The blisters may break open and form ulcers or open sores. It usually occurs in elderly persons and is rare in young people. Symptoms come and go. In most patients, the condition goes away within 6 years. The cause is not known, but may be related to immune system disorders.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bullous Pemphigoid" for support, advocacy or research.

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International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

Last Updated: 8 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bullous Pemphigoid" for support, advocacy or research.

Logo
International Pemphigus and Pemphigoid Foundation

The IPPF provides direct access to innovative and effective support that promotes the very best health care, improves quality of life, stimulates community resources, advocates for favorable government policies, accelerates the pace of scientific discovery and is the world’s best source of information on pemphigus and pemphigoid. We are compassionate in understanding, tireless in service, and relentless in advocating. One person at a time, we make a difference, building a community of care and hope.

http://www.pemphigus.org/

Last Updated: 8 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bullous Pemphigoid" returned 194 free, full-text research articles on human participants. First 3 results:

Human amnion membrane as a substrate for the detection of autoantibodies in pemphigus vulgaris and bullous pemphigoid.
 

Author(s): Tanya Sezin, Emily Avitan-Hersh, Margarita Indelman, Roni Moscona, Edmond Sabo, Rina Katz, Shimon Pollack, Reuven Bergman

Journal: Isr. Med. Assoc. J.. 2014 Apr;16(4):217-23.

 

Human amnion membrane (HAM) was suggested to be a superior antigenic substrate for immunoblotting in detecting autoantibodies of autoimmune bullous skin diseases.

Last Updated: 19 May 2014

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A case of childhood bullous pemphigoid with IgG and IgA autoantibodies to various domains of BP180.
 

Author(s): Manabu Osawa, Ikuko Ueda-Hayakawa, Taiki Isei, Ken Yoshimura, Shunpei Fukuda, Takashi Hashimoto, Hiroyuki Okamoto

Journal: J. Am. Acad. Dermatol.. 2014 Jun;70(6):e129-31.

 

Last Updated: 16 May 2014

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Childhood bullous pemphigoid.
 

Author(s): Dipti Das, Anupam Das, Panchami Debbarman

Journal: Indian Pediatr. 2013 Dec;50(12):1179.

 

Last Updated: 13 Jan 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bullous Pemphigoid" returned 10 free, full-text review articles on human participants. First 3 results:

Definitions and outcome measures for bullous pemphigoid: recommendations by an international panel of experts.
 

Author(s): Dedee F Murrell, Benjamin S Daniel, Pascal Joly, Luca Borradori, Masayuki Amagai, Takashi Hashimoto, Frédéric Caux, Branka Marinovic, Animesh A Sinha, Michael Hertl, Philippe Bernard, David Sirois, Giuseppe Cianchini, Janet A Fairley, Marcel F Jonkman, Amit G Pandya, David Rubenstein, Detlef Zillikens, Aimee S Payne, David Woodley, Giovanna Zambruno, Valeria Aoki, Carlo Pincelli, Luis Diaz, Russell P Hall, Michael Meurer, Jose M Mascaro, Enno Schmidt, Hiroshi Shimizu, John Zone, Robert Swerlick, Daniel Mimouni, Donna Culton, Jasna Lipozencic, Benjamin Bince, Sergei A Grando, Jean-Claude Bystryn, Victoria P Werth

Journal: J. Am. Acad. Dermatol.. 2012 Mar;66(3):479-85.

 

Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies ...

Last Updated: 20 Feb 2012

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Evidence-based treatments for pemphigus vulgaris, pemphigus foliaceus, and bullous pemphigoid: a systematic review.
 

Author(s): Sanjay Singh

Journal: Indian J Dermatol Venereol Leprol. ;77(4):456-69.

 

Pemphigus, bullous pemphigoid, and epidermolysis bullosa acquisita are autoimmune diseases of skin associated with considerable morbidity and sometimes mortality. There is no cure for these diseases.

Last Updated: 5 Jul 2011

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Bullous pemphigoid.
 

Author(s): Sujay Khandpur, Parul Verma

Journal: Indian J Dermatol Venereol Leprol. ;77(4):450-5.

 

Bullous pemphigoid (BP) is a relatively common autoimmune vesicobullous disease encountered in India. It is a subepidermal bullous disorder most commonly seen in the elderly and manifests as tense blisters on urticarial base, predominantly over flexures, and is associated with pruritus. ...

Last Updated: 5 Jul 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluation of Safety, Efficacy and Pharmacodynamic Effect of Bertilimumab in Patients With Bullous Pemphigoid
 

Status: Not yet recruiting

Condition Summary: Pemphigoid, Bullous Moderate; Pemphigoid, Bullous Severe

 

Last Updated: 26 Aug 2014

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Leflunomide Associated With Topical Corticosteroids for Bullous Pemphigoid
 

Status: Recruiting

Condition Summary: Bullous Pemphigoid

 

Last Updated: 3 Dec 2008

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Last Updated: 21 May 2014

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