Budd-Chiari Syndrome

Common Name(s)

Budd-Chiari Syndrome

Budd-Chiari syndrome is a rare disorder characterized by narrowing and obstruction of the veins of the liver. This narrowing or obstruction slows or prevents blood from flowing out of the liver and back to the heart which can lead to liver damage. While some people experience no symptoms, many experience fatigue, abdominal pain, nausea, and jaundice. Other associated findings include an accumulation of fluid in the abdomen (ascites), an enlarged spleen and/or liver, and severe bleeding in the esophagus. The severity of the disorder varies from case to case, depending on the site and number of affected veins. Drugs may be used to dissolve or decrease the size of the obstruction (if it is a clot). In some cases surgery is performed.  In most cases, the cause of Budd-Chiari syndrome is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Budd-Chiari Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Budd-Chiari Syndrome" returned 217 free, full-text research articles on human participants. First 3 results:

Images in clinical medicine. Abdominal-wall varices in the Budd-Chiari syndrome.
 

Author(s): Xingshun Qi, Guohong Han

Journal: N. Engl. J. Med.. 2014 May;370(19):1829.

 

Last Updated: 8 May 2014

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Clinical and pathological features and surgical treatment of Budd-Chiari syndrome-associated hepatocellular carcinoma.
 

Author(s): Ya-dong Wang, Huan-zhou Xue, Xiao Zhang, Zong-quan Xu, Qing-feng Jiang, Quan Shen, Miao Yu, Ke Li, Meng Jia

Journal: Chin. Med. J.. 2013 ;126(19):3632-8.

 

Budd-Chiari syndrome (BCS) is characterized by liver sinusoidal congestion, ischemic liver cell damage, and liver portal hypertension caused by hepatic venous outflow constriction. The aim of this research was to investigate the clinicopathological features of BCS-associated hepatocellular ...

Last Updated: 11 Oct 2013

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Acute iatrogenic Budd-Chiari syndrome following hepatectomy for hepatolithiasis: a report of two cases.
 

Author(s): Xue-Li Bai, Yi-Wen Chen, Qi Zhang, Long-Yun Ye, Yuan-Liang Xu, Liang Wang, Chun-Hui Cao, Shun-Liang Gao, Mohamed Adil Shah Khoodoruth, Bibi Zaina Ramjaun, Ai-Qiang Dong, Ting-Bo Liang

Journal: World J. Gastroenterol.. 2013 Sep;19(34):5763-8.

 

Budd-Chiari syndrome (BCS) is defined as hepatic venous outflow obstruction at any level from the small hepatic veins to the junction of the inferior vena cava (IVC) and the right atrium, regardless of the cause of obstruction. We present two cases of acute iatrogenic BCS and our ...

Last Updated: 16 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Budd-Chiari Syndrome" returned 13 free, full-text review articles on human participants. First 3 results:

The Budd-Chiari syndrome.
 

Author(s): Rania Hefaiedh, Mariem Cheikh, Lobna Marsaoui, Rym Ennaifer, Hayfa Romdhane, Houda Ben Nejma, Najet Bel Hadj, Nafaa Arfa, Mohamed Taher Khalfallah

Journal: Tunis Med. 2013 Jun;91(6):376-81.

 

The Budd-Chiari syndrome is a rare disease, often fatal if not treated optimally. It is characterized by a blocked hepatic venous outflow tract. aim: This review attempted to present pathophysiology, aetiologies,diagnosis and therapeutic modalities of the Budd-Chiari syndrome.

Last Updated: 22 Jul 2013

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Myeloproliferative neoplasms in Budd-Chiari syndrome and portal vein thrombosis: a meta-analysis.
 

Author(s): Jasper H Smalberg, Lidia R Arends, Dominique C Valla, Jean-Jacques Kiladjian, Harry L A Janssen, Frank W G Leebeek

Journal: Blood. 2012 Dec;120(25):4921-8.

 

Myeloproliferative neoplasms (MPNs) are the most common cause of Budd-Chiari syndrome (BCS) and nonmalignant, noncirrhotic portal vein thrombosis (PVT). In this meta-analysis, we determined the prevalence of MPNs and their subtypes as well as JAK2V617F and its diagnostic role in these ...

Last Updated: 17 Dec 2012

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Budd-Chiari syndrome in association with Behçet's disease: review of the literature.
 

Author(s): Daniela Carvalho, Fernando Oikawa, Nilce Mitiko Matsuda, Alice Tatsuko Yamada

Journal: Sao Paulo Med J. 2011 Mar;129(2):107-9.

 

The risk that patients with Behçet's disease may develop various thrombotic complications has been previously described. Although vascular complications from Budd-Chiari syndrome associated with Behçet's disease have been described, the pathogenic mechanisms are still unknown. Severe ...

Last Updated: 23 May 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 11 Jul 2014

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Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study
 

Status: Recruiting

Condition Summary: Hepatic Veno-Occlusive Disease

 

Last Updated: 13 Jan 2014

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Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients
 

Status: Recruiting

Condition Summary: Pulmonary Veno-Occlusive Disease; Hepatic Veno-Occlusive Disease; Mucositis

 

Last Updated: 6 Jul 2010

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