Budd-Chiari Syndrome

Common Name(s)

Budd-Chiari Syndrome

Budd-Chiari syndrome is a rare disorder characterized by narrowing and obstruction of the veins of the liver. This narrowing or obstruction slows or prevents blood from flowing out of the liver and back to the heart which can lead to liver damage. While some people experience no symptoms, many experience fatigue, abdominal pain, nausea, and jaundice. Other associated findings include an accumulation of fluid in the abdomen (ascites), an enlarged spleen and/or liver, and severe bleeding in the esophagus. The severity of the disorder varies from case to case, depending on the site and number of affected veins. Drugs may be used to dissolve or decrease the size of the obstruction (if it is a clot). In some cases surgery is performed.  In most cases, the cause of Budd-Chiari syndrome is unknown.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Budd-Chiari Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Budd-Chiari Syndrome" returned 215 free, full-text research articles on human participants. First 3 results:

Correction of the Scimitar syndrome, a rare cardiac venous anomaly, leading to Budd-Chiari syndrome: a case report.
 

Author(s): Marie-Pia Assoignon, Paul Christiaens, Wim Laleman

Journal:

 

Scimitar syndrome is a congenital heart disease characterized by an abnormal drainage of the right lung into the inferior vena cava, the right atrium or a variety of venous connections from the anomalous pulmonary vein to a systemic vein. This left-to-right shunt induces pulmonary ...

Last Updated: 20 Aug 2014

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Images in clinical medicine. Abdominal-wall varices in the Budd-Chiari syndrome.
 

Author(s): Xingshun Qi, Guohong Han

Journal: N. Engl. J. Med.. 2014 May;370(19):1829.

 

Last Updated: 8 May 2014

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Budd-Chiari syndrome as an initial presentation of hepatocellular carcinoma: a case report.
 

Author(s): Lavinia Alice Bălăceanu, Camelia Cristina Diaconu, Gheorghiţa Aron

Journal: Med Ultrason. 2014 Jun;16(2):172-4.

 

We report the case of a 84-year-old admitted with symptoms of congestive heart failure. Ultrasonography revealed a hyperechoic nodule in the left lobe of the liver, with a peripheral hypoechoic rim, multiple irregular hypoechoic nodules in both hepatic lobes, portal vein, inferior ...

Last Updated: 5 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Budd-Chiari Syndrome" returned 13 free, full-text review articles on human participants. First 3 results:

Scientific publications on portal vein thrombosis and Budd-Chiari syndrome: a global survey of the literature.
 

Author(s): Xingshun Qi, Jia Jia, Weirong Ren, Man Yang, Valerio De Stefano, Juan Wang, Daiming Fan

Journal: J Gastrointestin Liver Dis. 2014 Mar;23(1):65-71.

 

Portal vein thrombosis (PVT) and Budd-Chiari syndrome (BCS) are two rare vascular disorders of the liver that can lead to life-threatening complications. We conducted a global survey to systematically analyze the scientific publications in the fields of PVT and BCS.

Last Updated: 1 Apr 2014

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The Budd-Chiari syndrome.
 

Author(s): Rania Hefaiedh, Mariem Cheikh, Lobna Marsaoui, Rym Ennaifer, Hayfa Romdhane, Houda Ben Nejma, Najet Bel Hadj, Nafaa Arfa, Mohamed Taher Khalfallah

Journal: Tunis Med. 2013 Jun;91(6):376-81.

 

The Budd-Chiari syndrome is a rare disease, often fatal if not treated optimally. It is characterized by a blocked hepatic venous outflow tract. aim: This review attempted to present pathophysiology, aetiologies,diagnosis and therapeutic modalities of the Budd-Chiari syndrome.

Last Updated: 22 Jul 2013

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Myeloproliferative neoplasms in Budd-Chiari syndrome and portal vein thrombosis: a meta-analysis.
 

Author(s): Jasper H Smalberg, Lidia R Arends, Dominique C Valla, Jean-Jacques Kiladjian, Harry L A Janssen, Frank W G Leebeek

Journal: Blood. 2012 Dec;120(25):4921-8.

 

Myeloproliferative neoplasms (MPNs) are the most common cause of Budd-Chiari syndrome (BCS) and nonmalignant, noncirrhotic portal vein thrombosis (PVT). In this meta-analysis, we determined the prevalence of MPNs and their subtypes as well as JAK2V617F and its diagnostic role in these ...

Last Updated: 17 Dec 2012

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Budd-Chiari Syndrome in China: Balloon Angioplasty Alone or Combined With Stent Placement?
 

Status: Recruiting

Condition Summary: Budd-Chiari Syndrome

 

Last Updated: 25 Jul 2014

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Last Updated: 11 Jul 2014

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Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study
 

Status: Recruiting

Condition Summary: Hepatic Veno-Occlusive Disease

 

Last Updated: 13 May 2015

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