Bubonic Plague

Common Name(s)

Bubonic Plague

Plague is a bacterial infection caused by Yersinia pestis, mostly carried by rodents and fleas. Bubonic plague, a form of the plague, is passed to humans by a flea bite from an infected flea. Bubonic plague is characterized by swollen lymph nodes in the armpit or groin. Infection of the bacteria in the lungs can cause pneumonia (pneumonic plague), which causes fever, coughing, and breathing issues. If bubonic plague leads to pneumonic plague, the bacteria may be spread to other people through bodily fluids secreted by coughs of an infected individual. If caught early, bubonic plague can be treated with antibiotics, which clear the body system of the bacteria. However, pneumonic plague is very dangerous and deadly. Between 1-17 cases occur in the United States each year. Between 1000-2000 cases occur worldwide. Therefore it is importantn to seek medical treatment immediately if you believe you are showing symptoms of bubonic or pneumonic plague.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bubonic Plague" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bubonic Plague" returned 24 free, full-text research articles on human participants. First 3 results:

New insights into how Yersinia pestis adapts to its mammalian host during bubonic plague.
 

Author(s): Elizabeth Pradel, Nadine Lemaître, Maud Merchez, Isabelle Ricard, Angéline Reboul, Amélie Dewitte, Florent Sebbane

Journal:

 

Bubonic plague (a fatal, flea-transmitted disease) remains an international public health concern. Although our understanding of the pathogenesis of bubonic plague has improved significantly over the last few decades, researchers have still not been able to define the complete set ...

Last Updated: 28 Mar 2014

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Imaging early pathogenesis of bubonic plague: are neutrophils commandeered for lymphatic transport of bacteria?
 

Author(s): David M Bland, Deborah M Anderson

Journal:

 

Vector-borne infections begin in the dermis when a pathogen is introduced by an arthropod during a blood meal. Several barriers separate an invading pathogen from its replicative niche, including phagocytic cells in the dermis that activate immunity by engulfing would-be pathogens ...

Last Updated: 6 Nov 2013

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Yersinia pestis subverts the dermal neutrophil response in a mouse model of bubonic plague.
 

Author(s): Jeffrey G Shannon, Aaron M Hasenkrug, David W Dorward, Vinod Nair, Aaron B Carmody, B Joseph Hinnebusch

Journal:

 

The majority of human Yersinia pestis infections result from introduction of bacteria into the skin by the bite of an infected flea. Once in the dermis, Y. pestis can evade the host's innate immune response and subsequently disseminate to the draining lymph node (dLN). There, the ...

Last Updated: 28 Aug 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bubonic Plague" returned 1 free, full-text review articles on human participants. First 3 results:

Medieval and modern bubonic plague: some clinical continuities.
 

Author(s): Lars Walløe

Journal: Med Hist Suppl. 2008 ;(27):59-73.

 

Last Updated: 25 Jun 2008

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

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