Brown Syndrome

Common Name(s)

Brown Syndrome

Brown syndrome is an eye disorder characterized by abnormalities in the eye's ability to move. Specifically, the ability to look up and in is affected by a problem in the superior oblique muscle/tendon. The condition may be present at birth (congenital) or it may develop following surgery or as a result of inflammation or a problem with development. Some cases are constant while other are intermittent. Treatment depends upon the cause and severity of the movement disorder. Options include close observation, nonsteroidal anti-inflammatory agents like Ibuprofen, corticosteroids, and surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brown Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brown Syndrome" returned 54 free, full-text research articles on human participants. First 3 results:

Hematomyelia as a cause of brown-sequard's syndrome in a hypofibrinogenemic patient.
 

Author(s): B K Madhusudhan, J V Mahendra, , M Rohan, R Srinivasa

Journal: Neurol India. ;62(4):473.

 

Last Updated: 20 Sep 2014

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Cervical epidural haematoma causing Brown-Sequard syndrome: a case report.
 

Author(s): Arvind G Kulkarni, Kushal Nag, Sambhav Shah

Journal: J Orthop Surg (Hong Kong). 2013 Dec;21(3):372-4.

 

Brown-Sequard syndrome secondary to compression of the spinal cord by an epidural haematoma following minor trauma is rare. A 65-year-old woman presented with neck pain and sudden onset hemiplegia with contralateral anaesthesia. Magnetic resonance imaging showed a haematoma in the ...

Last Updated: 24 Dec 2013

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Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome.
 

Author(s): Atchayaram Nalini, Amelie Pandraud, Kin Mok, Henry Houlden

Journal: J. Neurol. Sci.. 2013 Nov;334(1-2):119-22.

 

Madras motor neuron disease (MMND), MMND variant (MMNDV) and Familial MMND (FMMND) have a unique geographic distribution predominantly reported from Southern India. The characteristic features are onset in young, weakness and wasting of limbs, multiple lower cranial nerve palsies ...

Last Updated: 11 Nov 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brown Syndrome" returned 10 free, full-text review articles on human participants. First 3 results:

Brown bowel syndrome: a rare complication in diseases associated with long-standing malabsorption.
 

Author(s): Heinz Albrecht, Alexander Hagel, Thomas de Rossi, Tilman T Rau, Thomas Kirchner, Markus F Neurath, Martin Raithel

Journal: Digestion. 2014 ;89(2):105-9.

 

Longtime chronic malabsorption may among other things cause a lack of liposoluble vitamins. Vitamin E deficiency can lead to formation of lipofuscin aggregates. Its deficiency is also associated with an increased lipofuscinosis of the bowel, i.e. brown bowel syndrome.

Last Updated: 28 Mar 2014

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The Brown-Vialetto-Van Laere and Fazio Londe syndrome revisited: natural history, genetics, treatment and future perspectives.
 

Author(s): Annet M Bosch, Kevin Stroek, Nico G Abeling, Hans R Waterham, Lodewijk Ijlst, Ronald J A Wanders

Journal:

 

The Brown-Vialetto-Van Laere syndrome is a rare neurological disorder which may present at all ages with sensorineural deafness, bulbar palsy and respiratory compromise. Fazio-Londe syndrome is considered to be the same disease entity. Recently it was demonstrated that in some patients ...

Last Updated: 11 Dec 2012

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Spontaneous epidural hematoma of thoracic spine presenting as Brown-Séquard syndrome: report of a case with review of the literature.
 

Author(s): Hong-Xin Cai, Chao Liu, Jian-Feng Zhang, Shuang-Lin Wan, Kenzo Uchida, Shun-Wu Fan

Journal: J Spinal Cord Med. 2011 ;34(4):432-6.

 

Spontaneous spinal epidural hematoma (SSEH) is an uncommon clinical entity. It produces a severe neurological deficit and prompt decompression is usually the first choice of treatment. Brown-Séquard syndrome is commonly seen in the setting of spinal trauma or an extramedullary spinal ...

Last Updated: 9 Sep 2011

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Different Metabolic Characteristics in the Presence of Brown Adipose Tissue in Humans
 

Status: Recruiting

Condition Summary: Metabolic Syndrome

 

Last Updated: 7 Sep 2011

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HIV Fat Redistribution and the Evaluation of Brown Fat
 

Status: Recruiting

Condition Summary: HIV Infections

 

Last Updated: 2 May 2014

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