Brown Syndrome

Common Name(s)

Brown Syndrome

Brown syndrome is an eye disorder characterized by abnormalities in the eye's ability to move. Specifically, the ability to look up and in is affected by a problem in the superior oblique muscle/tendon. The condition may be present at birth (congenital) or it may develop following surgery or as a result of inflammation or a problem with development. Some cases are constant while other are intermittent. Treatment depends upon the cause and severity of the movement disorder. Options include close observation, nonsteroidal anti-inflammatory agents like Ibuprofen, corticosteroids, and surgery.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brown Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brown Syndrome" returned 53 free, full-text research articles on human participants. First 3 results:

Madras motor neuron disease (MMND) is distinct from the riboflavin transporter genetic defects that cause Brown-Vialetto-Van Laere syndrome.
 

Author(s): Atchayaram Nalini, Amelie Pandraud, Kin Mok, Henry Houlden

Journal: J. Neurol. Sci.. 2013 Nov;334(1-2):119-22.

 

Madras motor neuron disease (MMND), MMND variant (MMNDV) and Familial MMND (FMMND) have a unique geographic distribution predominantly reported from Southern India. The characteristic features are onset in young, weakness and wasting of limbs, multiple lower cranial nerve palsies ...

Last Updated: 11 Nov 2013

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Management of Brown-Sequard syndrome in cervical disc diseases.
 

Author(s): Safwat Abouhashem, Mohamad Ammar, Mohamad Barakat, Essam Abdelhameed

Journal: Turk Neurosurg. 2013 ;23(4):470-5.

 

To raise the awareness of the appropriate management of unusual clinical presentation of cervical disc herniation.

Last Updated: 8 Oct 2013

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Fine mapping for Weaver syndrome in Brown Swiss cattle and the identification of 41 concordant mutations across NRCAM, PNPLA8 and CTTNBP2.
 

Author(s): Matthew McClure, Euisoo Kim, Derek Bickhart, Daniel Null, Tabatha Cooper, John Cole, George Wiggans, Paolo Ajmone-Marsan, Licia Colli, Enrico Santus, George E Liu, Steve Schroeder, Lakshmi Matukumalli, Curt Van Tassell, Tad Sonstegard

Journal: PLoS ONE. 2013 ;8(3):e59251.

 

Bovine Progressive Degenerative Myeloencephalopathy (Weaver Syndrome) is a recessive neurological disease that has been observed in the Brown Swiss cattle breed since the 1970's in North America and Europe. Bilateral hind leg weakness and ataxia appear in afflicted animals at 6 to ...

Last Updated: 25 Mar 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brown Syndrome" returned 9 free, full-text review articles on human participants. First 3 results:

The Brown-Vialetto-Van Laere and Fazio Londe syndrome revisited: natural history, genetics, treatment and future perspectives.
 

Author(s): Annet M Bosch, Kevin Stroek, Nico G Abeling, Hans R Waterham, Lodewijk Ijlst, Ronald J A Wanders

Journal:

 

The Brown-Vialetto-Van Laere syndrome is a rare neurological disorder which may present at all ages with sensorineural deafness, bulbar palsy and respiratory compromise. Fazio-Londe syndrome is considered to be the same disease entity. Recently it was demonstrated that in some patients ...

Last Updated: 11 Dec 2012

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Spontaneous epidural hematoma of thoracic spine presenting as Brown-Séquard syndrome: report of a case with review of the literature.
 

Author(s): Hong-Xin Cai, Chao Liu, Jian-Feng Zhang, Shuang-Lin Wan, Kenzo Uchida, Shun-Wu Fan

Journal: J Spinal Cord Med. 2011 ;34(4):432-6.

 

Spontaneous spinal epidural hematoma (SSEH) is an uncommon clinical entity. It produces a severe neurological deficit and prompt decompression is usually the first choice of treatment. Brown-Séquard syndrome is commonly seen in the setting of spinal trauma or an extramedullary spinal ...

Last Updated: 9 Sep 2011

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Lateral medullary infarction presenting as Brown-Séquard syndrome-like manifestation: a case report and literature review.
 

Author(s): Wei-Lun Chang, Der-Shin Ke, Tain-Junn Cheng

Journal: Acta Neurol Taiwan. 2010 Sep;19(3):204-7.

 

Lateral medullary infarction is not uncommon in clinical practice of neurology. This report describes a patient who initially presented with Brown-Séquard syndrome-like manifestation but was later diagnosed with acute infarction in the left lower lateral medulla.

Last Updated: 8 Sep 2010

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Different Metabolic Characteristics in the Presence of Brown Adipose Tissue in Humans
 

Status: Recruiting

Condition Summary: Metabolic Syndrome

 

Last Updated: 7 Sep 2011

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HIV Fat Redistribution and the Evaluation of Brown Fat
 

Status: Recruiting

Condition Summary: HIV Infections

 

Last Updated: 2 May 2014

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Effect of Temperature on Pain and Brown Adipose Activity in Fibromyalgia
 

Status: Recruiting

Condition Summary: Fibromyalgia; Pain

 

Last Updated: 22 Oct 2012

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