Emphysema

Common Name(s)

Emphysema

Emphysema is a chronic (long term) lung condition. It is a form of COPD (chronic obstructive pulmonary disease). The air you breathe goes into your lungs through airways. At the end of our airways in our lungs are tiny air sacs (alveoli). It is the air sacs that become damaged over time in emphysema. As the air sacs are damaged, their inner walls break down causing the sac to become larger. Larger sacs absorb less oxygen than those of normal size. The damage also causes difficulty breathing or shortness of breath. The damaged air sacs cannot be replaced.

Symptoms of emphysema may not occur until years after the damage to the air sacs begins. Symptoms may include shortness of breath, decreased mental alertness, and blue or gray fingertips or lips. Risk of developing emphysema is increased if there has been long-term exposure to airborne irritants including tobacco smoke, marijuana smoke, air pollution, and manufacturing fumes. A less common form of emphysema is caused by the lack of a special type of protein (alpha-1-antitrypsin). This type of emphysema is usually caused by a mutation or change in your genes and therefore will run in families.

To diagnosis emphysema, a physician may perform a variety of tests, which may include a chest x-ray to rule out other causes, lab tests to examine oxygen in the blood stream, and lung function tests to measure air flow in and out of the lungs. Treatment to relieve symptoms and slow the progression of the disease may include medications, therapy, or surgery. See a doctor if you have had unexplained shortness of breath for several months, particularly if it is getting worse or interfering with your daily activities. If you have been diagnosed with emphysema, talk with your doctor or specialist about the most current treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 829 free, full-text research articles on human participants. First 3 results:

Electrocardiogram in emphysema: a rapid bedside screening diagnostic tool.
 

Author(s): Nauman Khalid, Lovely Chhabra, David H Spodick

Journal: Tuberk Toraks. 2014 ;62(4):325-6.

 

Last Updated: 13 Jan 2015

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Telomerase mutations in smokers with severe emphysema.
 

Author(s): Susan E Stanley, Julian J L Chen, Joshua D Podlevsky, Jonathan K Alder, Nadia N Hansel, Rasika A Mathias, Xiaodong Qi, Nicholas M Rafaels, Robert A Wise, Edwin K Silverman, Kathleen C Barnes, Mary Armanios

Journal: J. Clin. Invest.. 2015 Feb;125(2):563-70.

 

Mutations in the essential telomerase genes TERT and TR cause familial pulmonary fibrosis; however, in telomerase-null mice, short telomeres predispose to emphysema after chronic cigarette smoke exposure. Here, we tested whether telomerase mutations are a risk factor for human emphysema ...

Last Updated: 3 Feb 2015

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Therapeutic management of massive subcutaneous emphysema, bilateral pneumothorax and pneumomediastinum after anterior cordectomy for in situ vocal cord carcinoma - case report.
 

Author(s): Cc Georgescu, C Margaritescu, I Osman, M Stoica, M Mitroi, V Surlin

Journal: Chirurgia (Bucur). ;109(6):822-6.

 

We present the case of a 70 year-old smoker patient, who was admitted in hospital for removal of a tumour located on the left vocal cord. After direct suspension laryngoscopy (with tumorbiopsy sampling), preliminary histopathological exam revealed an in situ carcinoma. At 2 weeks ...

Last Updated: 6 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 86 free, full-text review articles on human participants. First 3 results:

Emphysema: Imaging for Endoscopic Lung Volume Reduction.
 

Author(s): B Storbeck, T H Schröder, M Oldigs, K F Rabe, C Weber

Journal: Rofo. 2015 Jul;187(7):543-54.

 

Chronic obstructive pulmonary disease (COPD) is characterized by two entities, the more airway-predominant type ("bronchitis") on the one hand, and emphysema-predominant type on the other. Imaging via high-resolution computed tomography plays an important role in phenotyping COPD. ...

Last Updated: 20 Jun 2015

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Combined pulmonary fibrosis and emphysema: an increasingly recognized condition.
 

Author(s): Olívia Meira Dias, Bruno Guedes Baldi, André Nathan Costa, Carlos Roberto Ribeiro Carvalho

Journal: J Bras Pneumol. ;40(3):304-12.

 

Combined pulmonary fibrosis and emphysema (CPFE) has been increasingly recognized in the literature. Patients with CPFE are usually heavy smokers or former smokers with concomitant lower lobe fibrosis and upper lobe emphysema on chest HRCT scans. They commonly present with severe ...

Last Updated: 17 Jul 2014

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Subcutaneous emphysema--beyond the pneumoperitoneum.
 

Author(s): Douglas E Ott

Journal: JSLS. ;18(1):1-7.

 

Subcutaneous emphysema and gas extravasation outside of the peritoneal cavity during laparoscopy has consequences. Knowledge of the circumstances that increase the potential for subcutaneous emphysema is necessary for safe laparoscopy.

Last Updated: 31 Mar 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetics of the Combined Pulmonary Fibrosis and Emphysema Syndrome
 

Status: Recruiting

Condition Summary: Combined Pulmonary Fibrosis and Emphysema Syndrome; Pulmonary Fibrosis; Emphysema; Healthy Subjects

 

Last Updated: 7 May 2015

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Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
 

Status: Recruiting

Condition Summary: Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)

 

Last Updated: 19 May 2011

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