Emphysema

Common Name(s)

Emphysema

Emphysema is a chronic (long term) lung condition. It is a form of COPD (chronic obstructive pulmonary disease). The air you breathe goes into your lungs through airways. At the end of our airways in our lungs are tiny air sacs (alveoli). It is the air sacs that become damaged over time in emphysema. As the air sacs are damaged, their inner walls break down causing the sac to become larger. Larger sacs absorb less oxygen than those of normal size. The damage also causes difficulty breathing or shortness of breath. The damaged air sacs cannot be replaced.

Symptoms of emphysema may not occur until years after the damage to the air sacs begins. Symptoms may include shortness of breath, decreased mental alertness, and blue or gray fingertips or lips. Risk of developing emphysema is increased if there has been long-term exposure to airborne irritants including tobacco smoke, marijuana smoke, air pollution, and manufacturing fumes. A less common form of emphysema is caused by the lack of a special type of protein (alpha-1-antitrypsin). This type of emphysema is usually caused by a mutation or change in your genes and therefore will run in families.

To diagnosis emphysema, a physician may perform a variety of tests, which may include a chest x-ray to rule out other causes, lab tests to examine oxygen in the blood stream, and lung function tests to measure air flow in and out of the lungs. Treatment to relieve symptoms and slow the progression of the disease may include medications, therapy, or surgery. See a doctor if you have had unexplained shortness of breath for several months, particularly if it is getting worse or interfering with your daily activities. If you have been diagnosed with emphysema, talk with your doctor or specialist about the most current treatment options. Support groups are also a good source of information and support.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 1089 free, full-text research articles on human participants. First 3 results:

Subcutaneous cervical emphysema and pneumomediastinum due to a diastatic rupture of the cecum.
 

Author(s): R Vecchio, E Intagliata, F Basile, C Spataro, G Giulia, V Leanza, S Marchese

Journal: G Chir. ;36(6):272-5.

 

Pneumomediastinum usually occurs after esophageal or chest trauma. Subcutaneous cervical emphysema as a presentation of non-traumatic colonic perforation following colorectal cancer or diverticulitis, is very rare. We report a case of a patient with rectal cancer who developed a diastatic ...

Last Updated: 18 Feb 2016

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Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.
 

Author(s): Suzanne M Cloonan, Kimberly Glass, Maria E Laucho-Contreras, Abhiram R Bhashyam, Morgan Cervo, Maria A Pabón, Csaba Konrad, Francesca Polverino, Ilias I Siempos, Elizabeth Perez, Kenji Mizumura, Manik C Ghosh, Harikrishnan Parameswaran, Niamh C Williams, Kristen T Rooney, Zhi-Hua Chen, Monica P Goldklang, Guo-Cheng Yuan, Stephen C Moore, Dawn L Demeo, Tracey A Rouault, Jeanine M D'Armiento, Eric A Schon, Giovanni Manfredi, John Quackenbush, Ashfaq Mahmood, Edwin K Silverman, Caroline A Owen, Augustine M K Choi

Journal: Nat. Med.. 2016 Feb;22(2):163-74.

 

Chronic obstructive pulmonary disease (COPD) is linked to both cigarette smoking and genetic determinants. We have previously identified iron-responsive element-binding protein 2 (IRP2) as an important COPD susceptibility gene and have shown that IRP2 protein is increased in the lungs ...

Last Updated: 5 Feb 2016

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The influence of lung volume reduction with intrabronchial valves on the quality of life of patients with heterogeneous emphysema - a prospective study.
 

Author(s): Sylwia Szlubowska, Joanna Zalewska-Puchała, Anna Majda, Piotr Kocoń, Jerzy Soja, Maciej Gnass, Ewa Pasko, Adam Ćmiel, Artur Szlubowski, Jarosław Kużdżał

Journal: Pneumonol Alergol Pol. 2015 ;83(6):418-23.

 

A heterogeneous emphysema is one of the most severe forms of chronic obstructive pulmonary disease (COPD). In some cases, besides the standard pharmacotherapy, a new treatment option of emphysema can be used - bronchoscopic lung volume reduction (BLVR) with the use of intrabronchial valves.

Last Updated: 12 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 95 free, full-text review articles on human participants. First 3 results:

Emphysema: Imaging for Endoscopic Lung Volume Reduction.
 

Author(s): B Storbeck, T H Schröder, M Oldigs, K F Rabe, C Weber

Journal: Rofo. 2015 Jul;187(7):543-54.

 

Chronic obstructive pulmonary disease (COPD) is characterized by two entities, the more airway-predominant type ("bronchitis") on the one hand, and emphysema-predominant type on the other. Imaging via high-resolution computed tomography plays an important role in phenotyping COPD. ...

Last Updated: 20 Jun 2015

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[A newly-defined entity: combined pulmonary fibrosis and emphysema syndrome].
 

Author(s): Neslihan Özçelik, Savaş Özsu

Journal: Tuberk Toraks. 2015 ;63(1):48-52.

 

Combined pulmonary fibrosis and emphysema (CPFE) syndrome is a rare disease characterized with shortness of breath, upper lobe emphysema, lower lobe fibrosis and impairment of gas exchange. This syndrome is a disease usually seen in male smokers. Pulmonary hypertension is associated ...

Last Updated: 8 Apr 2015

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Segmental approach to lung volume reduction therapy for emphysema patients.
 

Author(s): Sourish Bandyopadhyay, Erik Henne, Avina Gupta, Robert Barry, Greg Snell, Charlie Strange, Felix J F Herth

Journal: Respiration. 2015 ;89(1):76-81.

 

Emphysema is often distributed heterogeneously throughout the lungs, even at the segmental level. It is important for interventional lung volume reduction therapies to target and treat the most diseased regions of the lung while preserving the less diseased functional regions. Identification ...

Last Updated: 9 Feb 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetics of the Combined Pulmonary Fibrosis and Emphysema Syndrome
 

Status: Recruiting

Condition Summary: Combined Pulmonary Fibrosis and Emphysema Syndrome; Pulmonary Fibrosis; Emphysema; Healthy Subjects

 

Last Updated: 7 May 2015

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Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
 

Status: Recruiting

Condition Summary: Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)

 

Last Updated: 19 May 2011

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