Emphysema

Common Name(s)

Emphysema

Emphysema is a chronic (long term) lung condition. It is a form of COPD (chronic obstructive pulmonary disease). The air you breathe goes into your lungs through airways. At the end of our airways in our lungs are tiny air sacs (alveoli). It is the air sacs that become damaged over time in emphysema. As the air sacs are damaged, their inner walls break down causing the sac to become larger. Larger sacs absorb less oxygen than those of normal size. The damage also causes difficulty breathing or shortness of breath. The damaged air sacs cannot be replaced.

Symptoms of emphysema may not occur until years after the damage to the air sacs begins. Symptoms may include shortness of breath, decreased mental alertness, and blue or gray fingertips or lips. Risk of developing emphysema is increased if there has been long-term exposure to airborne irritants including tobacco smoke, marijuana smoke, air pollution, and manufacturing fumes. A less common form of emphysema is caused by the lack of a special type of protein (alpha-1-antitrypsin). This type of emphysema is usually caused by a mutation or change in your genes and therefore will run in families.

To diagnosis emphysema, a physician may perform a variety of tests, which may include a chest x-ray to rule out other causes, lab tests to examine oxygen in the blood stream, and lung function tests to measure air flow in and out of the lungs. Treatment to relieve symptoms and slow the progression of the disease may include medications, therapy, or surgery. See a doctor if you have had unexplained shortness of breath for several months, particularly if it is getting worse or interfering with your daily activities. If you have been diagnosed with emphysema, talk with your doctor or specialist about the most current treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 1129 free, full-text research articles on human participants. First 3 results:

IMAGES IN CLINICAL MEDICINE. Pneumorrhachis, Pneumothorax, and Subcutaneous Emphysema.
 

Author(s): Christoph Straube, Martin Vazan

Journal: N. Engl. J. Med.. 2016 Sep;375(9):e18.

 

Last Updated: 1 Sep 2016

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Endobronchial Valves for Emphysema.
 

Author(s): Karin Klooster, Nick N H T ten Hacken, Dirk-Jan Slebos

Journal: N. Engl. J. Med.. 2016 Apr;374(14):1390.

 

Last Updated: 7 Apr 2016

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Combined Pulmonary Fibrosis and Emphysema Preceding Lupus Pleuritis.
 

Author(s): Yosuke Kamiya, Mikio Toyoshima, Norimichi Akiyama, Takafumi Suda

Journal: Intern. Med.. 2016 ;55(7):783-6.

 

An 83-year-old man, who was a former smoker, with anti-ribonucleoprotein (RNP) antibody-positive combined pulmonary fibrosis and emphysema presented with a cough and dyspnea. A chest radiograph showed bilateral pleural effusions. His laboratory data showed proteinuria and elevated ...

Last Updated: 4 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 97 free, full-text review articles on human participants. First 3 results:

Impact of COPD and emphysema on survival of patients with lung cancer: A meta-analysis of observational studies.
 

Author(s): Yong-Hua Gao, Wei-Jie Guan, Qi Liu, Hua-Qi Wang, Ya-Nan Zhu, Rong-Chang Chen, Guo-Jun Zhang

Journal: Respirology. 2016 Feb;21(2):269-79.

 

Both COPD and emphysema are associated with an increased incidence of lung cancer, but the impacts of these comorbidities on lung cancer prognosis are still unclear. Herein, we conducted a meta-analysis to clarify whether the presence of these comorbidities indicates poor survival ...

Last Updated: 18 Jan 2016

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Emphysema: Imaging for Endoscopic Lung Volume Reduction.
 

Author(s): B Storbeck, T H Schröder, M Oldigs, K F Rabe, C Weber

Journal: Rofo. 2015 Jul;187(7):543-54.

 

Chronic obstructive pulmonary disease (COPD) is characterized by two entities, the more airway-predominant type ("bronchitis") on the one hand, and emphysema-predominant type on the other. Imaging via high-resolution computed tomography plays an important role in phenotyping COPD. ...

Last Updated: 20 Jun 2015

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[A newly-defined entity: combined pulmonary fibrosis and emphysema syndrome].
 

Author(s): Neslihan Özçelik, Savaş Özsu

Journal: Tuberk Toraks. 2015 ;63(1):48-52.

 

Combined pulmonary fibrosis and emphysema (CPFE) syndrome is a rare disease characterized with shortness of breath, upper lobe emphysema, lower lobe fibrosis and impairment of gas exchange. This syndrome is a disease usually seen in male smokers. Pulmonary hypertension is associated ...

Last Updated: 8 Apr 2015

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Symptoms, Diagnosis, and Treatment

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There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Losartan Effects on Emphysema Progression
 

Status: Not yet recruiting

Condition Summary: Emphysema

 

Last Updated: 20 Jun 2016

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Assessment of Emphysema Using 1.5T MRI With UTE Pulse Sequences
 

Status: Recruiting

Condition Summary: Emphysema

 

Last Updated: 8 Jan 2015

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Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function
 

Status: Recruiting

Condition Summary: Emphysema

 

Last Updated: 12 Oct 2016

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