Emphysema

Common Name(s)

Emphysema

Emphysema is a chronic (long term) lung condition. It is a form of COPD (chronic obstructive pulmonary disease). The air you breathe goes into your lungs through airways. At the end of our airways in our lungs are tiny air sacs (alveoli). It is the air sacs that become damaged over time in emphysema. As the air sacs are damaged, their inner walls break down causing the sac to become larger. Larger sacs absorb less oxygen than those of normal size. The damage also causes difficulty breathing or shortness of breath. The damaged air sacs cannot be replaced.

Symptoms of emphysema may not occur until years after the damage to the air sacs begins. Symptoms may include shortness of breath, decreased mental alertness, and blue or gray fingertips or lips. Risk of developing emphysema is increased if there has been long-term exposure to airborne irritants including tobacco smoke, marijuana smoke, air pollution, and manufacturing fumes. A less common form of emphysema is caused by the lack of a special type of protein (alpha-1-antitrypsin). This type of emphysema is usually caused by a mutation or change in your genes and therefore will run in families.

To diagnosis emphysema, a physician may perform a variety of tests, which may include a chest x-ray to rule out other causes, lab tests to examine oxygen in the blood stream, and lung function tests to measure air flow in and out of the lungs. Treatment to relieve symptoms and slow the progression of the disease may include medications, therapy, or surgery. See a doctor if you have had unexplained shortness of breath for several months, particularly if it is getting worse or interfering with your daily activities. If you have been diagnosed with emphysema, talk with your doctor or specialist about the most current treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 1150 free, full-text research articles on human participants. First 3 results:

Genetic polymorphism in matrix metalloproteinase-9 and transforming growth factor-β1 and susceptibility to combined pulmonary fibrosis and emphysema in a Chinese population.
 

Author(s): Ling Xu, Wei Bian, Xiao-Hua Gu, Ce Shen

Journal: Kaohsiung J. Med. Sci.. 2017 Mar;33(3):124-129.

 

In this study, we aimed to explore the association of genetic polymorphism in matrix metalloproteinase-9 (MMP-9) and transforming growth factor-β1 (TGF-β1) and the susceptibility to combined pulmonary fibrosis and emphysema (CPFE). We examined the polymorphisms of the MMP-9 C-1562T ...

Last Updated: 3 Mar 2017

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Predicting Structure-Function Relations and Survival following Surgical and Bronchoscopic Lung Volume Reduction Treatment of Emphysema.
 

Author(s): Jarred R Mondoñedo, Béla Suki

Journal:

 

Lung volume reduction surgery (LVRS) and bronchoscopic lung volume reduction (bLVR) are palliative treatments aimed at reducing hyperinflation in advanced emphysema. Previous work has evaluated functional improvements and survival advantage for these techniques, although their effects ...

Last Updated: 9 Feb 2017

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Endobronchial valves for patients with heterogeneous emphysema and without interlobar collateral ventilation: open label treatment following the BeLieVeR-HIFi study.
 

Author(s): Zaid Zoumot, Claire Davey, Simon Jordan, William H McNulty, Denis H Carr, Matthew D Hind, Michael I Polkey, Pallav L Shah, Nicholas S Hopkinson

Journal: Thorax. 2017 Mar;72(3):277-279.

 

Outcomes in early trials of bronchoscopic lung volume reduction using endobronchial valves for the treatment of patients with advanced emphysema were inconsistent. However improvements in patient selection with focus on excluding those with interlobar collateral ventilation and homogeneous ...

Last Updated: 21 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 94 free, full-text review articles on human participants. First 3 results:

Emphysema: coiling up the lungs, trick or treat?
 

Author(s): M Bezzi, M Mondoni, C Sorino, P Solidoro

Journal: Minerva Med.. 2015 Aug;106(4 Suppl 3):9-16.

 

Lung volume reduction coil (LVRC) treatment is a minimally-invasive technique planned to achieve an improvement of exercise capacity and pulmonary function in subjects with advanced emphysema and hyperinflation. It has been proposed together with other bronchoscopic lung volume reduction ...

Last Updated: 18 Jul 2016

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Endobronchial Valve as Treatment of Emphysema Compared with Standard Medical Care: an Evidence-based Case Report.
 

Author(s): Eric D Tenda, Abraham Yakub

Journal: Acta Med Indones. 2016 Jan;48(1):70-5.

 

to determine the effectiveness of endobronchial valve placement as treatment of emphysema compared to medical care.

Last Updated: 31 May 2016

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The fissure: interlobar collateral ventilation and implications for endoscopic therapy in emphysema.
 

Author(s): Theodoor David Koster, Dirk-Jan Slebos

Journal:

 

In patients with severe emphysema, bronchoscopic lung volume reduction using one-way valves is a promising therapeutic option to improve lung function and quality of life. The goal of this treatment is to achieve a complete lobar atelectasis. In a significant proportion of patients, ...

Last Updated: 25 Apr 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Losartan Effects on Emphysema Progression
 

Status: Recruiting

Condition Summary: Emphysema

 

Last Updated: 26 Jun 2017

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Clinical Study to Evaluate the Exercise Capacity in Patients With Severe Emphysema Treated With Coils
 

Status: Not yet recruiting

Condition Summary: Pulmonary Emphysema

 

Last Updated: 9 Sep 2016

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