Emphysema

Common Name(s)

Emphysema

Emphysema is a chronic (long term) lung condition. It is a form of COPD (chronic obstructive pulmonary disease). The air you breathe goes into your lungs through airways. At the end of our airways in our lungs are tiny air sacs (alveoli). It is the air sacs that become damaged over time in emphysema. As the air sacs are damaged, their inner walls break down causing the sac to become larger. Larger sacs absorb less oxygen than those of normal size. The damage also causes difficulty breathing or shortness of breath. The damaged air sacs cannot be replaced.

Symptoms of emphysema may not occur until years after the damage to the air sacs begins. Symptoms may include shortness of breath, decreased mental alertness, and blue or gray fingertips or lips. Risk of developing emphysema is increased if there has been long-term exposure to airborne irritants including tobacco smoke, marijuana smoke, air pollution, and manufacturing fumes. A less common form of emphysema is caused by the lack of a special type of protein (alpha-1-antitrypsin). This type of emphysema is usually caused by a mutation or change in your genes and therefore will run in families.

To diagnosis emphysema, a physician may perform a variety of tests, which may include a chest x-ray to rule out other causes, lab tests to examine oxygen in the blood stream, and lung function tests to measure air flow in and out of the lungs. Treatment to relieve symptoms and slow the progression of the disease may include medications, therapy, or surgery. See a doctor if you have had unexplained shortness of breath for several months, particularly if it is getting worse or interfering with your daily activities. If you have been diagnosed with emphysema, talk with your doctor or specialist about the most current treatment options. Support groups are also a good source of information and support.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 1139 free, full-text research articles on human participants. First 3 results:

Emphysema and Airflow Obstruction in Non-Smoking Coal Miners with Pneumoconiosis.
 

Author(s): Bülent Altınsoy, İbrahim İlker Öz, Fatma Erboy, Meltem Tor, Figen Atalay

Journal:

 

BACKGROUND Accumulating evidence shows that functional impairment in subjects with coal workers' pneumoconiosis (CWP) is principally due to emphysema and airflow obstruction, rather than underlying restrictive mechanisms. However, cigarette smoking has remained a major confounder. ...

Last Updated: 13 Dec 2016

Go To URL
Severity of pulmonary emphysema and lung cancer: analysis using quantitative lobar emphysema scoring.
 

Author(s): Kyungsoo Bae, Kyung Nyeo Jeon, Seung Jun Lee, Ho Cheol Kim, Ji Young Ha, Sung Eun Park, Hye Jin Baek, Bo Hwa Choi, Soo Buem Cho, Jin Il Moon

Journal: Medicine (Baltimore). 2016 Nov;95(48):e5494.

 

The aim of this study was to determine the relationship between lobar severity of emphysema and lung cancer using automated lobe segmentation and emphysema quantification methods.This study included 78 patients (74 males and 4 females; mean age of 72 years) with the following conditions: ...

Last Updated: 30 Nov 2016

Go To URL
Urinary polyaromatic hydrocarbons are associated with adult emphysema, chronic bronchitis, asthma, and infections: US NHANES, 2011-2012.
 

Author(s): Ivy Shiue

Journal: Environ Sci Pollut Res Int. 2016 Dec;23(24):25494-25500.

 

Links between environmental chemicals and human health have emerged over the last few decades, but the effects from polyaromatic hydrocarbons were less studied, compared to other commonly known environmental chemicals such as heavy metals, phthalates, arsenic, phenols, pesticides, ...

Last Updated: 25 Oct 2016

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 94 free, full-text review articles on human participants. First 3 results:

Emphysema: coiling up the lungs, trick or treat?
 

Author(s): M Bezzi, M Mondoni, C Sorino, P Solidoro

Journal: Minerva Med.. 2015 Aug;106(4 Suppl 3):9-16.

 

Lung volume reduction coil (LVRC) treatment is a minimally-invasive technique planned to achieve an improvement of exercise capacity and pulmonary function in subjects with advanced emphysema and hyperinflation. It has been proposed together with other bronchoscopic lung volume reduction ...

Last Updated: 18 Jul 2016

Go To URL
Endobronchial Valve as Treatment of Emphysema Compared with Standard Medical Care: an Evidence-based Case Report.
 

Author(s): Eric D Tenda, Abraham Yakub

Journal: Acta Med Indones. 2016 Jan;48(1):70-5.

 

to determine the effectiveness of endobronchial valve placement as treatment of emphysema compared to medical care.

Last Updated: 31 May 2016

Go To URL
The fissure: interlobar collateral ventilation and implications for endoscopic therapy in emphysema.
 

Author(s): Theodoor David Koster, Dirk-Jan Slebos

Journal:

 

In patients with severe emphysema, bronchoscopic lung volume reduction using one-way valves is a promising therapeutic option to improve lung function and quality of life. The goal of this treatment is to achieve a complete lobar atelectasis. In a significant proportion of patients, ...

Last Updated: 25 Apr 2016

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 10 Apr 2017

Go to URL
Losartan Effects on Emphysema Progression
 

Status: Not yet recruiting

Condition Summary: Emphysema

 

Last Updated: 1 Mar 2017

Go to URL
Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function
 

Status: Recruiting

Condition Summary: Emphysema

 

Last Updated: 24 Apr 2017

Go to URL