Emphysema

Common Name(s)

Emphysema

Emphysema gradually damages the air sacs in your lungs, making you progressively more short of breath. These sacs are clustered like bunches of grapes. In emphysema, the inner walls of the sacs weaken and eventually rupture, creating one larger air space instead of many small ones. This reduces the surface area that may be used to collect oxygen, leading to a decrease in the amount of oxygen that reaches your bloodstream. The only symptom usually associated with emphysema is shortness of breath, and may not occur until years after the damage to the air sacs begins. See a doctor if you’ve had unexplained shortness of breath for several months, particularly if it’s getting worse or interfering with your daily activities. Together with chronic bronchitis, emphysema is one component of Chronic Obstructive Pulmonary Disease (COPD).

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Emphysema" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Emphysema" returned 767 free, full-text research articles on human participants. First 3 results:

Images in clinical medicine. Gastric emphysema.
 

Author(s): Ulises Garza, Christopher Gayer

Journal: N. Engl. J. Med.. 2014 May;370(22):e33.

 

Last Updated: 29 May 2014

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Agonistic induction of PPARγ reverses cigarette smoke-induced emphysema.
 

Author(s): Ming Shan, Ran You, Xiaoyi Yuan, Michael V Frazier, Paul Porter, Alexander Seryshev, Jeong-Soo Hong, Li-zhen Song, Yiqun Zhang, Susan Hilsenbeck, Lawrence Whitehead, Nazanin Zarinkamar, Sarah Perusich, David B Corry, Farrah Kheradmand

Journal: J. Clin. Invest.. 2014 Mar;124(3):1371-81.

 

The development of emphysema in humans and mice exposed to cigarette smoke is promoted by activation of an adaptive immune response. Lung myeloid dendritic cells (mDCs) derived from cigarette smokers activate autoreactive Th1 and Th17 cells. mDC-dependent activation of T cell subsets ...

Last Updated: 4 Mar 2014

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Diagnostic electrocardiographic dyad criteria of emphysema in left ventricular hypertrophy.
 

Author(s): Swapnil S Lanjewar, Lovely Chhabra, Vinod K Chaubey, Saurabh Joshi, Ganesh Kulkarni, Chandrasekhar Kothagundla, Sudesh Kaul, David H Spodick

Journal: Int J Chron Obstruct Pulmon Dis. 2013 ;8():591-4.

 

The electrocardiographic diagnostic dyad of emphysema, namely a combination of the frontal vertical P-vector and a narrow QRS duration, can serve as a quasidiagnostic marker for emphysema, with specificity close to 100%. We postulated that the presence of left ventricular hypertrophy ...

Last Updated: 2 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Emphysema" returned 81 free, full-text review articles on human participants. First 3 results:

Cardiovascular function in pulmonary emphysema.
 

Author(s): Dina Visca, Marina Aiello, Alfredo Chetta

Journal: Biomed Res Int. 2013 ;2013():184678.

 

Chronic obstructive pulmonary disease (COPD) and chronic cardiovascular disease, such as coronary artery disease, congestive heart failure, and cardiac arrhythmias, have a strong influence on each other, and systemic inflammation has been considered as the main linkage between them. ...

Last Updated: 25 Dec 2013

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Compressed air blast injury with palpebral, orbital, facial, cervical, and mediastinal emphysema through an eyelid laceration: a case report and review of literature.
 

Author(s): Takahiro Hiraoka, Tomohiro Ogami, Fumiki Okamoto, Tetsuro Oshika

Journal:

 

To the best of our knowledge, only 14 cases of orbital or periorbital compressed air injuries from air guns or hoses have been reported in the literature.

Last Updated: 17 Jan 2014

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The impact of emphysema in pulmonary fibrosis.
 

Author(s): Vincent Cottin

Journal: Eur Respir Rev. 2013 Jun;22(128):153-7.

 

Several groups have described a syndrome in which idiopathic pulmonary fibrosis (IPF) coexists with pulmonary emphysema. This comes as no surprise since both diseases are associated with a history of exposure to cigarette smoke. The syndrome of combined pulmonary fibrosis and emphysema ...

Last Updated: 3 Jun 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Endoscopic Lung Volume Reduction in Patients With Advanced Emphysema Due to alpha1 Antitrypsin Deficiency
 

Status: Recruiting

Condition Summary: Hereditary Emphysema (Alpha 1-antitrypsin Deficiency)

 

Last Updated: 19 May 2011

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Management of Patients With Alpha-1 Antitrypsin Deficiency Associated Emphysema
 

Status: Recruiting

Condition Summary: Alpha 1-Antitrypsin Deficiency; Emphysema

 

Last Updated: 6 Dec 2010

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