Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 4164 free, full-text research articles on human participants. First 3 results:

Renal clear cell carcinoma metastasis to salivary glands - a series of 9 cases: clinico-pathological study.
 

Author(s): H Majewska, A Skálová, K Radecka, D Stodulski, M Hyrcza, C Stankiewicz, W Biernat

Journal: Pol J Pathol. 2016 Mar;67(1):39-45.

 

Metastatic tumors involving salivary glands arising from the non-head and neck area are very rare. Renal cell carcinoma (RCC) is known for its high propensity for metastasis to unusual localizations. RCC metastasis to the maxillofacial area is an uncommon event (16%), but metastasis ...

Last Updated: 15 May 2016

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Clinical Impact of Pancreatic Metastases from Renal Cell Carcinoma: A Multicenter Retrospective Analysis.
 

Author(s): Paolo Grassi, Ludovic Doucet, Palma Giglione, Viktor Grünwald, Bohuslav Melichar, Luca Galli, Ugo De Giorgi, Roberto Sabbatini, Cinzia Ortega, Matteo Santoni, Aristotelis Bamias, Elena Verzoni, Lisa Derosa, Hana Studentova, Monica Pacifici, Jorgelina Coppa, Vincenzo Mazzaferro, Filippo de Braud, Camillo Porta, Bernard Escudier, Giuseppe Procopio

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Pancreatic metastases from renal cell carcinoma are uncommon and their prognostic significance is not well defined. In this analysis we evaluated the outcome of patients with pancreatic metastases treated with either targeted therapies or local treatment to the pancreas. Patients ...

Last Updated: 12 Apr 2016

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The Effect of Preoperative Apolipoprotein A-I on the Prognosis of Surgical Renal Cell Carcinoma: A Retrospective Large Sample Study.
 

Author(s): Shengjie Guo, Xiaobo He, Qian Chen, Guangwei Yang, Kai Yao, Pei Dong, Yunlin Ye, Dong Chen, Zhiling Zhang, Zike Qin, Zhuowei Liu, Zaishang Li, Yunfei Xue, Meng Zhang, Ruiwu Liu, Fangjian Zhou, Hui Han

Journal: Medicine (Baltimore). 2016 Mar;95(12):e3147.

 

The prognostic value of serum lipid-profile in renal cell cancer (RCC) remains unknown. The purpose of the study is to explore the association between the serum lipid-profile and RCC patients.The levels of preoperative serum lipid-profile (including cholesterol, triglycerides, high-density ...

Last Updated: 26 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 416 free, full-text review articles on human participants. First 3 results:

Review of succinate dehydrogenase-deficient renal cell carcinoma with focus on clinical and pathobiological aspects.
 

Author(s): N Kuroda, K Yorita, M Nagasaki, Y Harada, C Ohe, J Jeruc, M R Raspollini, M Michal, O Hes, M B Amin

Journal: Pol J Pathol. 2016 Mar;67(1):3-7.

 

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) was first identified in 2004 and has been integrated into the 2016 WHO classification of RCC. Succinate dehydrogenase (SDH) is an enzyme complex composed of four protein subunits (SDHA, SDHB, SDHC and SDHD). The tumor ...

Last Updated: 15 May 2016

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Current management and future directions in the treatment of advanced renal cell carcinoma-a latin american perspective: 10 years in review.
 

Author(s): Oren Smaletz

Journal: Int Braz J Urol. ;41(5):835-43.

 

The worldwide incidence of kidney cancer is estimated at 337,860 new cases per year in the International Agency for Research on Cancer's GLOBOCAN 2012 update, with an estimated 143,369 deaths annually. Over the past 10 years, there have been significant advances in the treatment of ...

Last Updated: 22 Dec 2015

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Prognostic Value of High CXCR4 Expression in Renal Cell Carcinoma: A System Review and Meta-Analysis.
 

Author(s): Yuefeng Du, Qingzhi Long, Bing Guan, Lijun Mu

Journal: Dis. Markers. 2015 ;2015():568980.

 

Recent studies have shown that CXC chemokine receptor 4 (CXCR4) is involved in the progression and metastasis of renal cell carcinoma (RCC). However, the prognostic value of CXCR4 expression in RCC remains controversial. The aim of our meta-analysis is to evaluate the prognostic value ...

Last Updated: 3 Nov 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Advanced or Metastatic Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma; Clear-cell Renal Cell Carcinoma; Papillary Renal Cell Carcinoma; Kidney Diseases; Kidney Neoplasms; Metastatic Renal Cell Carcinoma

 

Last Updated: 17 Aug 2016

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Immunotherapy Study for Metastatic Renal Cell Cancer
 

Status: Recruiting

Condition Summary: Metastatic Renal Cell Carcinoma; Metastatic Clear-cell Renal Cancer; Recurrent Renal Cell Carcinoma; Refractory Renal Cell Carcinoma; Metastatic Kidney Cancer

 

Last Updated: 2 Feb 2016

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A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: ccRCC; RCC; Kidney Cancer; Clear Cell Renal Cell Carcinoma; Renal Cell Carcinoma

 

Last Updated: 29 Apr 2016

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