Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 4661 free, full-text research articles on human participants. First 3 results:

Alternative Response Criteria and Clinical Risk Factors for Assessing Tumor Response in Patients With Metastatic Renal Cell Carcinoma Who Are Receiving Salvage Therapy.
 

Author(s): Hyunseon C Kang, Shiva Gupta, Wei Wei, Lina Lu, Marc R Matrana, Nizar M Tannir, Haesun Choi

Journal: AJR Am J Roentgenol. 2017 Dec;209(6):1278-1284.

 

The purpose of this study is to compare the prognostic value of various solid tumor response criteria as well as the additive value of clinical risk factors in patients with advanced renal cell carcinoma (RCC).

Last Updated: 31 Dec 1969

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Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.
 

Author(s): R B Verheijen, L E Swart, J H Beijnen, J H M Schellens, A D R Huitema, N Steeghs

Journal: Cancer Chemother. Pharmacol.. 2017 Dec;80(6):1171-1178.

 

Pazopanib is an angiogenesis inhibitor approved for the treatment of renal cell carcinoma and soft tissue sarcoma. Post hoc analysis of a clinical trial demonstrated a relationship between pazopanib trough concentrations (Cmin) and treatment efficacy. The aim of this study was to ...

Last Updated: 31 Dec 1969

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Expression level of CXCL7 in peripheral blood cells is a potential biomarker for the diagnosis of renal cell carcinoma.
 

Author(s): Toshiro Kinouchi, Motohide Uemura, Cong Wang, Yu Ishizuya, Yoshiyuki Yamamoto, Takuji Hayashi, Kyosuke Matsuzaki, Wataru Nakata, Takahiro Yoshida, Kentaro Jingushi, Atsunari Kawashima, Takeshi Ujike, Akira Nagahara, Kazutoshi Fujita, Ryoichi Imamura, Yuko Ueda, Kaori Kitae, Kazutake Tsujikawa, Norio Nonomura

Journal: Cancer Sci.. 2017 Dec;108(12):2495-2502.

 

There are no blood biomarkers for the diagnosis of renal cell carcinoma (RCC) in routine clinical use. We focused on the gene expression profile of peripheral blood cells obtained from RCC patients to discover novel biomarkers for RCC diagnosis. Using microarray analysis and quantitative ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 552 free, full-text review articles on human participants. First 3 results:

Treatment of renal cell carcinoma: Current status and future directions.
 

Author(s): Pedro C Barata, Brian I Rini

Journal: CA Cancer J Clin. 2017 Nov;67(6):507-524.

 

Answer questions and earn CME/CNE Over the past 12 years, medical treatment for renal cell carcinoma (RCC) has transitioned from a nonspecific immune approach (in the cytokine era), to targeted therapy against vascular endothelial growth factor (VEGF), and now to novel immunotherapy ...

Last Updated: 31 Dec 1969

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Metastasis of renal cell carcinoma to the thyroid gland 9 years after nephrectomy: A case report and literature review.
 

Author(s): Zeki Bayraktar, Selami Albayrak

Journal:

 

We report a case presenting with thyroid and lung metastases of renal cell carcinoma that was treated with molecular targeted therapy followed metastasectomy. A 52-year-old female underwent radical nephrectomy of right renal cell carcinoma in 2007. The patient presented 9 years after ...

Last Updated: 31 Dec 1969

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Phosphatase and tensin homolog (PTEN) expression on oncologic outcome in renal cell carcinoma: A systematic review and meta-analysis.
 

Author(s): Lu Tang, Xintao Li, Yu Gao, Luyao Chen, Liangyou Gu, Jianwen Chen, Xiangjun Lyu, Yu Zhang, Xu Zhang

Journal:

 

The phosphatase and tensin homolog (PTEN) gene is suggested to be a dormant tumor suppressor. However, the prognostic value of the loss of PTEN expression in renal cell carcinoma (RCC) remains controversial. Therefore, we conducted a meta-analysis to evaluate the association of PTEN ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Study of TAK-228 In Patients With Previously Treated Metastatic Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma

 

Last Updated: 1 Dec 2017

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A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma

 

Last Updated: 27 Jul 2017

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Molecular Determinants for Therapy Response on Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma

 

Last Updated: 31 Jul 2014

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