Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 2326 free, full-text research articles on human participants. First 3 results:

Overall survival in renal-cell carcinoma with pazopanib versus sunitinib.
 

Author(s): Robert J Motzer, Thomas E Hutson, Lauren McCann, Keith Deen, Toni K Choueiri

Journal: N. Engl. J. Med.. 2014 May;370(18):1769-70.

 

Last Updated: 5 May 2014

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Assessment of progression-free survival as a surrogate end-point for overall survival in patients with metastatic renal cell carcinoma.
 

Author(s): S Négrier, A G Bushmakin, J C Cappelleri, B Korytowsky, R Sandin, C Charbonneau, M D Michaelson, R A Figlin, R J Motzer

Journal: Eur. J. Cancer. 2014 Jul;50(10):1766-71.

 

To determine suitability of progression-free survival (PFS) as a surrogate end-point for overall survival (OS), we evaluated the relationship between PFS and OS in 750 treatment-naïve metastatic renal cell carcinoma (mRCC) patients who received sunitinib or interferon-alpha (IFN-α) ...

Last Updated: 2 Jun 2014

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Chromosome 3p loss of heterozygosity is associated with a unique metabolic network in clear cell renal carcinoma.
 

Author(s): Francesco Gatto, Intawat Nookaew, Jens Nielsen

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Mar;111(9):E866-75.

 

Several common oncogenic pathways have been implicated in the emergence of renowned metabolic features in cancer, which in turn are deemed essential for cancer proliferation and survival. However, the extent to which different cancers coordinate their metabolism to meet these requirements ...

Last Updated: 5 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 251 free, full-text review articles on human participants. First 3 results:

Renal mucinous tubular and spindle cell carcinoma: a report of 8 cases and review of the literature.
 

Author(s): Xiao-rong Wu, Yong-hui Chen, Jian-jun Sha, Ling Zhao, Ji-wei Huang, Juan-Jie Bo, Dong-ming Liu, Yi-ran Huang

Journal:

 

Mucinous tubular and spindle cell carcinoma of kidney (MTSCC-K) is a rare variant of renal tumor. The current data show most of MTSCCs are of low malignant potential and rare cases metastatic to lymph nodes have been reported; however, the recorded computed tomography (CT) and follow ...

Last Updated: 28 Feb 2014

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Concurrent primary carcinoid tumor arising within mature teratoma and clear cell renal cell carcinoma in the horseshoe kidney: report of a rare case and review of the literature.
 

Author(s): Ke Sun, Qihan You, Ming Zhao, Hongtian Yao, Hua Xiang, Lijun Wang

Journal:

 

Primary carcinoid tumor arising in a mature teratoma of the horseshoe kidney is exceptionally rare and only 4 such cases have been reported in the world literature to date. The simultaneous occurrence of different subtypes of renal cell carcinoma (RCC) or RCC coexistence with non-RCC ...

Last Updated: 14 Nov 2013

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Progress of molecular targeted therapies for advanced renal cell carcinoma.
 

Author(s): Alessandro Conti, Matteo Santoni, Consuelo Amantini, Luciano Burattini, Rossana Berardi, Giorgio Santoni, Stefano Cascinu, Giovanni Muzzonigro

Journal: Biomed Res Int. 2013 ;2013():419176.

 

Vascular endothelial growth factor (VEGF) plays a crucial role in tumor angiogenesis. VEGF expression in metastatic renal cell carcinoma (mRCC) is mostly regulated by hypoxia, predominantly via the hypoxia-induced factor (HIF)/Von Hippel-Lindau (VHL) pathway. Advances in our knowledge ...

Last Updated: 4 Oct 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

AMG 172 First in Human Study in Patients With Kidney Cancer
 

Status: Recruiting

Condition Summary: Renal Cell Adenocarcinoma; Clear Cell Renal Carcinoma; Clear Cell Renal Cell Carcinoma; Renal Cell Carcinoma

 

Last Updated: 17 Jul 2014

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Immunotherapy Study for Metastatic Renal Cell Cancer
 

Status: Not yet recruiting

Condition Summary: Metastatic Renal Cell Carcinoma; Metastatic Clear-cell Renal Cancer; Recurrent Renal Cell Carcinoma; Refractory Renal Cell Carcinoma; Metastatic Kidney Cancer

 

Last Updated: 28 Jan 2014

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Phase 3 Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (RCC)
 

Status: Recruiting

Condition Summary: Advanced Renal Cell Carcinoma; Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma

 

Last Updated: 25 Jun 2014

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