Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 4224 free, full-text research articles on human participants. First 3 results:

Papillary Renal-Cell Carcinoma.
 

Author(s): W Marston Linehan, Maria J Merino, Christopher J Ricketts

Journal: N. Engl. J. Med.. 2016 May;374(20):1991.

 

Last Updated: 19 May 2016

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Renal clear cell carcinoma metastasis to salivary glands - a series of 9 cases: clinico-pathological study.
 

Author(s): H Majewska, A Skálová, K Radecka, D Stodulski, M Hyrcza, C Stankiewicz, W Biernat

Journal: Pol J Pathol. 2016 Mar;67(1):39-45.

 

Metastatic tumors involving salivary glands arising from the non-head and neck area are very rare. Renal cell carcinoma (RCC) is known for its high propensity for metastasis to unusual localizations. RCC metastasis to the maxillofacial area is an uncommon event (16%), but metastasis ...

Last Updated: 15 May 2016

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PBRM1 Regulates the Expression of Genes Involved in Metabolism and Cell Adhesion in Renal Clear Cell Carcinoma.
 

Author(s): Basudev Chowdhury, Elizabeth G Porter, Jane C Stewart, Christina R Ferreira, Matthew J Schipma, Emily C Dykhuizen

Journal:

 

Polybromo-1 (PBRM1) is a component of the PBAF (Polybromo-associated-BRG1- or BRM-associated factors) chromatin remodeling complex and is the second most frequently mutated gene in clear-cell renal cell Carcinoma (ccRCC). Mutation of PBRM1 is believed to be an early event in carcinogenesis, ...

Last Updated: 22 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 422 free, full-text review articles on human participants. First 3 results:

Review of succinate dehydrogenase-deficient renal cell carcinoma with focus on clinical and pathobiological aspects.
 

Author(s): N Kuroda, K Yorita, M Nagasaki, Y Harada, C Ohe, J Jeruc, M R Raspollini, M Michal, O Hes, M B Amin

Journal: Pol J Pathol. 2016 Mar;67(1):3-7.

 

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) was first identified in 2004 and has been integrated into the 2016 WHO classification of RCC. Succinate dehydrogenase (SDH) is an enzyme complex composed of four protein subunits (SDHA, SDHB, SDHC and SDHD). The tumor ...

Last Updated: 15 May 2016

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[Chromophobe renal cell carcinoma: about four cases and review of the literature].
 

Author(s): Yddoussalah Othmane, Lahyani Mounir, Karmouni Tarik, Elkhader Khalid, Koutani Abdellatif, Ibn Attya Andaloussi Ahmed

Journal:

 

Last Updated: 18 Feb 2016

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Current management and future directions in the treatment of advanced renal cell carcinoma-a latin american perspective: 10 years in review.
 

Author(s): Oren Smaletz

Journal: Int Braz J Urol. ;41(5):835-43.

 

The worldwide incidence of kidney cancer is estimated at 337,860 new cases per year in the International Agency for Research on Cancer's GLOBOCAN 2012 update, with an estimated 143,369 deaths annually. Over the past 10 years, there have been significant advances in the treatment of ...

Last Updated: 22 Dec 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Dose Escalation, Safety and Activity Study of CDX-014 in Patients With Advanced or Metastatic Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma; Clear-cell Renal Cell Carcinoma; Papillary Renal Cell Carcinoma; Kidney Diseases; Kidney Neoplasms; Metastatic Renal Cell Carcinoma

 

Last Updated: 19 Sep 2016

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A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: ccRCC; RCC; Kidney Cancer; Clear Cell Renal Cell Carcinoma; Renal Cell Carcinoma

 

Last Updated: 29 Apr 2016

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Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma; Hereditary Leiomyomatosis and Renal Cell Cancer; Papillary Renal Cell Carcinoma, Sporadic

 

Last Updated: 31 Aug 2016

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