Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 2590 free, full-text research articles on human participants. First 3 results:

Renal small cell carcinoma presenting with solitary lumbar intradural metastasis.
 

Author(s): Anirudh Srinivasan, Sivashanmugam Dhandapani, Debajyoti Chatterjee, Vijai Simha

Journal: Neurol India. ;62(5):561-3.

 

Last Updated: 12 Nov 2014

Go To URL
Circulating biomarkers of one-carbon metabolism in relation to renal cell carcinoma incidence and survival.
 

Author(s): Mattias Johansson, Anouar Fanidi, David C Muller, Julie K Bassett, Øivind Midttun, Stein Emil Vollset, Ruth C Travis, Domenico Palli, Amalia Mattiello, Sabina Sieri, Antonia Trichopoulou, Pagona Lagiou, Dimitrios Trichopoulos, Börje Ljungberg, Göran Hallmans, Elisabete Weiderpass, Guri Skeie, Carlos A González, Miren Dorronsoro, Petra H Peeters, H Bas Bueno-de-Mesquita, Martine M Ros, Marie-Christine Boutron Ruault, Guy Fagherazzi, Françoise Clavel, María-José Sánchez, Aurelio Barricarte Gurrea, Carmen Navarro, J Ramon Quiros, Kim Overvad, Anne Tjønneland, Krassimira Aleksandrova, Paolo Vineis, Marc J Gunter, Rudolf Kaaks, Graham Giles, Caroline Relton, Elio Riboli, Heiner Boeing, Per Magne Ueland, Gianluca Severi, Paul Brennan

Journal:

 

The etiology of renal cell carcinoma (RCC) is only partially understood, but a metabolic component appears likely. We investigated biomarkers of one-carbon metabolism and RCC onset and survival.

Last Updated: 7 Nov 2014

Go To URL
Radiotherapy as an immunological booster in patients with metastatic melanoma or renal cell carcinoma treated with high-dose Interleukin-2: evaluation of biomarkers of immunologic and therapeutic response.
 

Author(s): Laura Ridolfi, Francesco de Rosa, Ruggero Ridolfi, Giorgia Gentili, Linda Valmorri, Emanuela Scarpi, Elisabetta Parisi, Antonino Romeo, Massimo Guidoboni

Journal:

 

Tumor cells killed by radiation therapy (RT) are a potentially good source of antigens for dendritic cell (DC) uptake and presentation to T-cells. RT upregulates cell death receptors such as Fas/CD95 and MHC-I, induces the expression of co-stimulatory molecules on tumor cells, and ...

Last Updated: 7 Oct 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 272 free, full-text review articles on human participants. First 3 results:

Renal cell carcinoma.
 

Author(s): Eric Jonasch, Jianjun Gao, W Kimryn Rathmell

Journal:

 

The treatment of renal cell carcinoma (RCC) has changed greatly over the past 15 years. Progress in the surgical management of the primary tumor and increased understanding of the molecular biology and genomics of the disease have led to the development of new therapeutic agents. ...

Last Updated: 11 Nov 2014

Go To URL
[Prognostic factors and associated models for metastatic renal cell carcinoma treated with targeted therapy].
 

Author(s): Zheng Zheng, Han-zhong Li, Yong-qiang Li

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2014 Aug;36(4):450-3.

 

Since 2006, tyrosine kinase inhibitors and anti-angiogenic drugs have revolutionized the treatment of metastatic renal cell carcinoma by improving progression-free survival and overall survival. The prognostic factors in metastatic renal cell carcinoma treated by targeted therapy ...

Last Updated: 1 Sep 2014

Go To URL
Frontiers in clinical and molecular diagnostics and staging of metastatic clear cell renal cell carcinoma.
 

Author(s): Anna M Czarnecka, Anna Kornakiewicz, Wojciech Kukwa, Cezary Szczylik

Journal: Future Oncol. 2014 May;10(6):1095-111.

 

The last few years have brought advances in the understanding of the molecular biology of metastatic clear cell renal cell carcinoma (RCC). Both preclinical research and clinical trials brought together results from the latest advancements in RCC diagnostic and staging. Understanding ...

Last Updated: 19 Jun 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase 3 Trial of Autologous Dendritic Cell Immunotherapy (AGS-003) Plus Standard Treatment of Advanced Renal Cell Carcinoma (RCC)
 

Status: Recruiting

Condition Summary: Advanced Renal Cell Carcinoma; Renal Cell Carcinoma; Metastatic Renal Cell Carcinoma

 

Last Updated: 18 Dec 2014

Go to URL
AMG 172 First in Human Study in Patients With Kidney Cancer
 

Status: Recruiting

Condition Summary: Renal Cell Adenocarcinoma; Clear Cell Renal Carcinoma; Clear Cell Renal Cell Carcinoma; Renal Cell Carcinoma

 

Last Updated: 17 Oct 2014

Go to URL
Immunotherapy Study for Metastatic Renal Cell Cancer
 

Status: Not yet recruiting

Condition Summary: Metastatic Renal Cell Carcinoma; Metastatic Clear-cell Renal Cancer; Recurrent Renal Cell Carcinoma; Refractory Renal Cell Carcinoma; Metastatic Kidney Cancer

 

Last Updated: 28 Aug 2014

Go to URL