Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 4151 free, full-text research articles on human participants. First 3 results:

The Complete Response to Targeted Drugs Without Surgery or Radiotherapy: A Case of Pituitary Metastasis From Renal Cell Carcinoma.
 

Author(s): Mehrdad Payandeh, Masoud Sadeghi, Edris Sadeghi

Journal: Acta Med Iran. 2016 Sep;54(9):617-619.

 

Pituitary gland metastasis was seen in elderly patients, and the incidence of pituitary metastasis is 1% to 4% of all cancer patients. Renal cell carcinoma is a primary malignancy in only 2.6% of pituitary metastases. We reported a 50-year-old man with pituitary metastasis from renal ...

Last Updated: 11 Nov 2016

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Adjuvant Sunitinib in High-Risk Renal-Cell Carcinoma after Nephrectomy.
 

Author(s): Alain Ravaud, Robert J Motzer, Hardev S Pandha, Daniel J George, Allan J Pantuck, Anup Patel, Yen-Hwa Chang, Bernard Escudier, Frede Donskov, Ahmed Magheli, Giacomo Carteni, Brigitte Laguerre, Piotr Tomczak, Jan Breza, Paola Gerletti, Mariajose Lechuga, Xun Lin, Jean-Francois Martini, Krishnan Ramaswamy, Michelle Casey, Michael Staehler, Jean-Jacques Patard,

Journal: N. Engl. J. Med.. 2016 Dec;375(23):2246-2254.

 

Background Sunitinib, a vascular endothelial growth factor pathway inhibitor, is an effective treatment for metastatic renal-cell carcinoma. We sought to determine the efficacy and safety of sunitinib in patients with locoregional renal-cell carcinoma at high risk for tumor recurrence ...

Last Updated: 10 Oct 2016

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Renal atrophy after stereotactic body radiotherapy for renal cell carcinoma.
 

Author(s): Takaya Yamamoto, Noriyuki Kadoya, Ken Takeda, Haruo Matsushita, Rei Umezawa, Kiyokazu Sato, Masaki Kubozono, Kengo Ito, Yojiro Ishikawa, Maiko Kozumi, Noriyoshi Takahashi, Yu Katagiri, Hiroshi Onishi, Keiichi Jingu

Journal:

 

Renal atrophy is observed in an irradiated kidney. The aim of this study was to determine dose-volume histogram parameters and other factors that predict renal atrophy after 10-fraction stereotactic body radiotherapy (SBRT) for primary renal cell carcinoma (RCC).

Last Updated: 27 May 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 427 free, full-text review articles on human participants. First 3 results:

The Evolution of Systemic Therapy in Metastatic Renal Cell Carcinoma.
 

Author(s): Thomas E Hutson, Gregory R Thoreson, Robert A Figlin, Brian I Rini

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():113-7.

 

The treatment landscape for renal cell carcinoma (RCC) is a dynamic process that has seen considerable change in recent years. We have seen a rebirth of original breakthroughs with immune checkpoint inhibitors showing promise in patients with treatment-refractory disease. The optimal ...

Last Updated: 2 Jun 2016

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Review of succinate dehydrogenase-deficient renal cell carcinoma with focus on clinical and pathobiological aspects.
 

Author(s): N Kuroda, K Yorita, M Nagasaki, Y Harada, C Ohe, J Jeruc, M R Raspollini, M Michal, O Hes, M B Amin

Journal: Pol J Pathol. 2016 Mar;67(1):3-7.

 

Succinate dehydrogenase (SDH)-deficient renal cell carcinoma (RCC) was first identified in 2004 and has been integrated into the 2016 WHO classification of RCC. Succinate dehydrogenase (SDH) is an enzyme complex composed of four protein subunits (SDHA, SDHB, SDHC and SDHD). The tumor ...

Last Updated: 15 May 2016

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Balancing treatment efficacy, toxicity and complication risk in elderly patients with metastatic renal cell carcinoma.
 

Author(s): R R H van den Brom, S C van Es, A M Leliveld, J A Gietema, G A P Hospers, I J de Jong, E G E de Vries, S F Oosting

Journal: Cancer Treat. Rev.. 2016 May;46():63-72.

 

The number of elderly patients with renal cell carcinoma is rising. Elderly patients differ from their younger counterparts in, among others, higher incidence of comorbidity and reduced organ function. Age influences outcome of surgery, and therefore has to be taken into account in ...

Last Updated: 29 May 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase II Study of Cyberknife Radiosurgery for Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma

 

Last Updated: 26 Oct 2016

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Molecular Determinants for Therapy Response on Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma

 

Last Updated: 31 Jul 2014

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Post Marketing Surveillance for ICE-SENSEā„¢3 a Cryotherapy Treatment of Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma

 

Last Updated: 17 Jan 2016

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