Renal cell carcinoma

Common Name(s)

Renal cell carcinoma

Renal cell carcinoma (RCC) is one of the most common types of kidney cancers seen in adults. RCC occurs more often in men between the ages of 50 to 70. The kidneys help get rid of waste in the body. There are small tubes in the kidneys that help filter waste from the blood and help make urine. RCC occurs when cells start growing uncontrollably in the lining of these small tubes. Symptoms may not appear in the early stages of renal cell carcinoma, which is why renal cell carcinoma is normally advanced when found. Later symptoms may include blood in urine, a lump in the abdomen, weight loss, anemia, and loss of appetite. If untreated, it may spread to the lymph nodes, lungs, liver, adrenal glands, brain, or bones.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Renal cell carcinoma" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Renal cell carcinoma" returned 4077 free, full-text research articles on human participants. First 3 results:

Preoperative Plasma Fibrinogen Level as a Significant Prognostic Factor in Patients With Localized Renal Cell Carcinoma After Surgical Treatment.
 

Author(s): Hakmin Lee, Sang Eun Lee, Seok-Soo Byun, Hyeon Hoe Kim, Cheol Kwak, Sung Kyu Hong

Journal: Medicine (Baltimore). 2016 Jan;95(4):e2626.

 

We sought to investigate the association of preoperative fibrinogen levels with clinicopathologic outcomes after surgical treatment of nonmetastatic renal cell carcinoma. We reviewed the records of 1511 patients who had their fibrinogen levels measured preceding surgery. The associations ...

Last Updated: 30 Jan 2016

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Chromophobe renal cell carcinoma occurring in the renal allograft of a transplant recipient presenting with weight loss.
 

Author(s): Mohammed Mahdi Althaf, Mohammed S Al-Sunaid, Mohamed Said Abdelsalam, Lutfi A Alkorbi, Turki O Al-Hussain, Mohammed Anas Dababo, Naveed Haq

Journal: Saudi J Kidney Dis Transpl. 2016 Jan;27(1):139-43.

 

The incidence of renal cell carcinomas (RCCs) in renal transplant recipients is reported as 1.1-1.5% in the native kidneys and 0.22-0.25% in the renal allograft. There are no data to support routine surveillance for tumors in transplant recipients. Most reported cases of RCCs occurring ...

Last Updated: 20 Jan 2016

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Renal cell carcinoma in patient with crossed fused renal ectopia.
 

Author(s): Ozgur Cakmak, Cemal Selcuk Isoglu, Ercument Aziz Peker, Huseyin Tarhan, Ulku Kucuk, Orcun Celik, Ferruh Zorlu, Yusuf Ozlem Ilbey

Journal:

 

Primary renal cell carcinomas have rarely been reported in patients with crossed fused renal ectopia. We presented a patient with right to left crossed fused kidney harbouring renal tumor. The most frequent tumor encountered in crossed fused renal ectopia is renal cell carcinoma. ...

Last Updated: 15 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Renal cell carcinoma" returned 406 free, full-text review articles on human participants. First 3 results:

Current management and future directions in the treatment of advanced renal cell carcinoma-a latin american perspective: 10 years in review.
 

Author(s): Oren Smaletz

Journal: Int Braz J Urol. ;41(5):835-43.

 

The worldwide incidence of kidney cancer is estimated at 337,860 new cases per year in the International Agency for Research on Cancer's GLOBOCAN 2012 update, with an estimated 143,369 deaths annually. Over the past 10 years, there have been significant advances in the treatment of ...

Last Updated: 22 Dec 2015

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Contralateral tumor seeding of renal cell carcinoma mimicking late metastasis of liver after laparoscopic nephrectomy: A case report with review of the literature.
 

Author(s): Özgür Haki Yüksel, Caglar Yildirim, Ahmet Ürkmez, Serkan Akan, Ayhan Verit

Journal:

 

Laparoscopic surgery has been increasingly used every day in the management of urologic malignancies. Even though it seems as a minimally invasive surgery, during these interventions tumor seeding, as seen in open surgery, confronts us as a rarely seen serious risk. Herein, we have ...

Last Updated: 2 Oct 2015

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Prognostic Significance of Hypoxia-Inducible Factor Expression in Renal Cell Carcinoma: A PRISMA-compliant Systematic Review and Meta-Analysis.
 

Author(s): Yang Fan, Hongzhao Li, Xin Ma, Yu Gao, Luyao Chen, Xintao Li, Xu Bao, Qingshan Du, Yu Zhang, Xu Zhang

Journal: Medicine (Baltimore). 2015 Sep;94(38):e1646.

 

The prognostic value of hypoxia-inducible factor (HIF) in renal cell carcinoma (RCC) has been evaluated in a large number of studies, but the reports were inconsistent and remained inconclusive. Therefore, we conducted a systematic review and meta-analysis to clarify the significance ...

Last Updated: 25 Sep 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Immunotherapy Study for Metastatic Renal Cell Cancer
 

Status: Recruiting

Condition Summary: Metastatic Renal Cell Carcinoma; Metastatic Clear-cell Renal Cancer; Recurrent Renal Cell Carcinoma; Refractory Renal Cell Carcinoma; Metastatic Kidney Cancer

 

Last Updated: 2 Feb 2016

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A Phase 1, Dose-Escalation Trial of PT2385 Tablets In Patients With Advanced Clear Cell Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: ccRCC; RCC; Kidney Cancer; Clear Cell Renal Cell Carcinoma; Renal Cell Carcinoma

 

Last Updated: 29 Apr 2016

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Vandetanib in Combination With Metformin in People With HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma
 

Status: Recruiting

Condition Summary: Renal Cell Carcinoma; Hereditary Leiomyomatosis and Renal Cell Cancer; Papillary Renal Cell Carcinoma, Sporadic

 

Last Updated: 9 Jun 2016

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