Metastatic cancer

Common Name(s)

Metastatic cancer

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Metastatic cancer" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Metastatic cancer" returned 4538 free, full-text research articles on human participants. First 3 results:

Elevated O-GlcNAcylation of Extracellular Vesicle Proteins Derived from Metastatic Colorectal Cancer Cells.
 

Author(s): Parunya Chaiyawat, Churat Weeraphan, Pukkavadee Netsirisawan, Daranee Chokchaichamnankit, Chantragan Srisomsap, Jisnuson Svasti, Voraratt Champattanachai

Journal: Cancer Genomics Proteomics. ;13(5):387-98.

 

O-GlcNAcylation is a single sugar attachment of serine and/or threonine residues on intracellular proteins. Recent reports reveal that it can modify several secretory proteins; however, the underlying mechanisms are largely unexplored.

Last Updated: 27 Aug 2016

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Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer.
 

Author(s): Colin C Pritchard, Joaquin Mateo, Michael F Walsh, Navonil De Sarkar, Wassim Abida, Himisha Beltran, Andrea Garofalo, Roman Gulati, Suzanne Carreira, Rosalind Eeles, Olivier Elemento, Mark A Rubin, Dan Robinson, Robert Lonigro, Maha Hussain, Arul Chinnaiyan, Jake Vinson, Julie Filipenko, Levi Garraway, Mary-Ellen Taplin, Saud AlDubayan, G Celine Han, Mallory Beightol, Colm Morrissey, Belinda Nghiem, Heather H Cheng, Bruce Montgomery, Tom Walsh, Silvia Casadei, Michael Berger, Liying Zhang, Ahmet Zehir, Joseph Vijai, Howard I Scher, Charles Sawyers, Nikolaus Schultz, Philip W Kantoff, David Solit, Mark Robson, Eliezer M Van Allen, Kenneth Offit, Johann de Bono, Peter S Nelson

Journal: N. Engl. J. Med.. 2016 Aug;375(5):443-53.

 

Inherited mutations in DNA-repair genes such as BRCA2 are associated with increased risks of lethal prostate cancer. Although the prevalence of germline mutations in DNA-repair genes among men with localized prostate cancer who are unselected for family predisposition is insufficient ...

Last Updated: 13 Aug 2016

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Survival Outcomes of Concurrent Treatment with Docetaxel and Androgen Deprivation Therapy in Metastatic Castration-Resistant Prostate Cancer.
 

Author(s): Ho Seong Jang, Kyo Chul Koo, Kang Su Cho, Byung Ha Chung

Journal: Yonsei Med. J.. 2016 Sep;57(5):1070-8.

 

Docetaxel-based chemotherapy (DTX) improves overall survival (OS) of men with metastatic castration-resistant prostate cancer (mCRPC). Considering the potential existence of androgen receptors that remain active at this stage, we aimed to assess the impact of the combined use of androgen ...

Last Updated: 12 Jul 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Metastatic cancer" returned 474 free, full-text review articles on human participants. First 3 results:

ESR1 mutations: Moving towards guiding treatment decision-making in metastatic breast cancer patients.
 

Author(s): Lindsay Angus, Nick Beije, Agnes Jager, John W M Martens, Stefan Sleijfer

Journal: Cancer Treat. Rev.. 2017 Jan;52():33-40.

 

Mutations in the gene coding for the estrogen receptor (ER), ESR1, have been associated with acquired endocrine resistance in patients with ER-positive metastatic breast cancer (MBC). Functional studies revealed that these ESR1 mutations lead to constitutive activity of the ER, meaning ...

Last Updated: 25 Nov 2016

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First-line therapy in HER2 positive metastatic breast cancer: is the mosaic fully completed or are we missing additional pieces?
 

Author(s): Alessandra Fabi, Paola Malaguti, Sabrina Vari, Francesco Cognetti

Journal:

 

The discovery of human epidermal growth factor receptor 2 (HER2) and its role in the biology of breast cancer and the subsequent development of HER2-targeted therapies, have dramatically improved clinical outcomes for women with early-stage and advanced HER2-positive breast cancer ...

Last Updated: 30 Jun 2016

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Local Therapy for Limited Metastatic Non-Small Cell Lung Cancer: What Are the Options and Is There a Benefit?
 

Author(s): Puneeth Iyengar, Steven Lau, Jessica S Donington, Robert D Suh

Journal: Am Soc Clin Oncol Educ Book. 2016 ;35():e460-7.

 

Distant metastasis is common in non-small cell lung cancer (NSCLC) and typically associated with poor prognosis. Aggressive local therapy including surgery and/or radiation for limited metastatic disease from colorectal cancer and sarcoma is associated with survival benefit and has ...

Last Updated: 2 Jun 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 14 Oct 2015

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Last Updated: 2 Jan 2017

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Clinical Sequencing Project for Metastatic Cancer Patients for Personalized Cancer Clinic.
 

Status: Not yet recruiting

Condition Summary: Metastatic Cancer

 

Last Updated: 28 Dec 2015

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