Dysthymia

Common Name(s)

Dysthymia, Persistent depressive disorder, Chronic depression

Dysthymia is a less severe, but long term form of depression. Although the depressed state of dysthymia is not as severe as with major depression, it can be just as disabling. Symptoms of dysthymia include low self-esteem, feelings of hopelessness and despair, inability to find pleasure or interest in activities and life, social withdrawal, always feeling tired, feelings of guilt or brooding about the past. Dysthymia is less likely to cause changes in sleep patterns and excessive weight gain or loss than those suffering from major depression. Dysthymia is diagnosed when depressive symptoms last for more than two years in adults (or one year in children) and a person has not been symptom-free for more than two months at a time. Individuals with dysthymia may manage to function well enough in their daily life that they are not aware they have an illness. They may believe their symptoms are just really a part of who they are. They may not know that if they seek treatment they can be helped.

About 3-6% of the population is affected by dysthymia. People with dysthymia often have their first symptoms earlier in life than those with major depressive disorder or bipolar disorder. Dysthymia sometimes runs in families but is believed to be caused by a combination of genetics and stresses in the person’s life and environment. It is important to realize that, like depression, dysthymia is a chemical imbalance in the brain and is treatable. Treatment may include support groups, medication, talk therapy, or other strategies. Talk to your doctor to decide on the best treatment options if you or a family member has dysthymia. Support groups are also a good source of up to date information and can help connect you with others affected by depression. See also depression.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Dysthymia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Dysthymia" returned 29 free, full-text research articles on human participants. First 3 results:

Quality of life among post-menopausal women due to oxidative stress boosted by dysthymia and anxiety.
 

Author(s): Martha A Sánchez-Rodríguez, Lizett Castrejón-Delgado, Mariano Zacarías-Flores, Alicia Arronte-Rosales, Víctor Manuel Mendoza-Núñez

Journal:

 

Menopause is the onset of aging in women. During this process, some women experience physical changes that may impact upon their psychological and social status, also affecting their quality of life. Furthermore, several psychological changes following menopause have been shown to ...

Last Updated: 4 Jan 2017

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Dysthymia increases the risk of temporomandibular disorder: A population-based cohort study (A STROBE-Compliant Article).
 

Author(s): Shang-Lun Lin, Shang-Liang Wu, Shun-Yao Ko, Ching-Hsiang Lu, Diew-Wei Wang, Ren-Jy Ben, Chi-Ting Horng, Jung-Wu Yang

Journal: Medicine (Baltimore). 2016 Jul;95(29):e4271.

 

Numerous studies have investigated the relationship between depression and temporomandibular disorders (TMD), but the conclusions remain vague. The aim of this study was to examine the causal effect between depression and TMD.The reporting of this study conforms to the STROBE statement. ...

Last Updated: 22 Jul 2016

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Improving work outcomes of dysthymia (persistent depressive disorder) in an employed population.
 

Author(s): David A Adler, Debra Lerner, Zachary L Visco, Annabel Greenhill, Hong Chang, Elina Cymerman, Francisca Azocar, William H Rogers

Journal: Gen Hosp Psychiatry. ;37(4):352-9.

 

To test the effectiveness of a work-focused intervention (WFI) on the work outcomes of employed adults with dysthymia.

Last Updated: 4 Jun 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Dysthymia" returned 6 free, full-text review articles on human participants. First 3 results:

Drug treatments for patients with dysthymia.
 

Author(s): Clarissa Kripke

Journal: Am Fam Physician. 2004 Oct;70(7):1269-70.

 

Last Updated: 28 Oct 2004

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The substituted benzamides and their clinical potential on dysthymia and on the negative symptoms of schizophrenia.
 

Author(s): L Pani, G L Gessa

Journal: Mol. Psychiatry. 2002 ;7(3):247-53.

 

In this paper the historical and scientific background that led to the use of substituted benzamides in two apparently unrelated clinical conditions namely dysthymic disorder and schizophrenia will be reviewed, in order to understand if a common mechanism of action may support this ...

Last Updated: 28 Mar 2002

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Proposed endophenotypes of dysthymia: evolutionary, clinical and pharmacogenomic considerations.
 

Author(s): A B Niculescu, H S Akiskal

Journal: Mol. Psychiatry. 2001 Jul;6(4):363-6.

 

Dysthymia is highly prevalent--though underdiagnosed--occurring in at least 3% of the population. We conceptualize it as the clinical extension of adaptive traits that have developed during evolution to cope with stress and failure. A classification of dysthymias into anxious and ...

Last Updated: 9 Jul 2001

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Schema Therapy for Chronic Depression
 

Status: Not yet recruiting

Condition Summary: Chronic Depressive Disorder; Dysthymic Disorder

 

Last Updated: 22 Mar 2017

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Antidepressant Response in the Treatment of Depressive Symptoms and Frailty Characteristics in Older Adults
 

Status: Recruiting

Condition Summary: Major Depressive Disorder; Dysthymic Disorder; Depressive Disorder, NOS

 

Last Updated: 27 Dec 2016

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A Trial of Cognitive Behavioral Therapy in Familial Dysautonomia
 

Status: Recruiting

Condition Summary: Dysthymia; Anxiety Disorders; Familial Dysautonomia; Paroxysmal Hypertension; Autosomal Recessive Disease

 

Last Updated: 5 Jan 2017

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