Bronchopulmonary Dysplasia

Common Name(s)

Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia (BPD) is a chronic lung condition that affects newborn babies, specifically premature and low birth weight babies. Premature infants have fragile, often under developed, lungs that become irritated or injured easily and are in need of a breathing machine. Symptoms to look for in a baby include bluish skin (cyanosis), flaring of nostrils, rapid/shallow breathing, and grunting sounds. Infants with BPD are cared for in the NICU with oxygen therapy/ventilators and proper fluid and nutrient uptake for weeks to months in the hospital. Because these babies are at a greater risk for severe and repeated respiratory infections, it is important to take additional precautions such as limiting contact with those who may be infected by a respiratory virus and washing your hands before touching the baby.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchopulmonary Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchopulmonary Dysplasia" returned 265 free, full-text research articles on human participants. First 3 results:

Tracheal Aspirate Levels of the Matricellular Protein SPARC Predict Development of Bronchopulmonary Dysplasia.
 

Author(s): Antonia P Popova, Tracy X Cui, Niko Kaciroti, Adam M Goldsmith, Marisa J Linn, Gloria S Pryhuber, Marc B Hershenson

Journal:

 

Isolation of tracheal aspirate mesenchymal stromal cells (MSCs) from premature infants has been associated with increased risk of bronchopulmonary dysplasia (BPD). MSCs show high levels of mRNAs encoding matricellular proteins, non-structural extracellular proteins that regulate cell-matrix ...

Last Updated: 15 Dec 2015

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Longitudinal assessment of the lung mechanics of very low birth weight preterm infants with and without bronchopulmonary dysplasia.
 

Author(s): Rosane Reis de Mello, Kátia Silveira da Silva, Anniele Medeiros Costa, José Roberto de Moraes Ramos

Journal: Sao Paulo Med J. ;133(5):401-7.

 

Prematurity has been correlated with altered lung mechanics. Some infants develop lung injury as a consequence of lung immaturity, invasive mechanical ventilation and exposure to oxygen, thus resulting in bronchopulmonary dysplasia. The aim here was to compare the lung mechanics of ...

Last Updated: 9 Dec 2015

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Intussusceptive-like angiogenesis in human fetal lung xenografts: Link with bronchopulmonary dysplasia-associated microvascular dysangiogenesis?
 

Author(s): Monique E De Paepe, Sharon Chu, Susan J Hall, Elizabeth McDonnell-Clark, Nicholas E Heger, Christoph Schorl, Quanfu Mao, Kim Boekelheide

Journal: Exp. Lung Res.. 2015 ;41(9):477-88.

 

Human fetal lung xenografts display an unusual pattern of non-sprouting, plexus-forming angiogenesis that is reminiscent of the dysmorphic angioarchitecture described in bronchopulmonary dysplasia (BPD). The aim of this study was to determine the clinicopathological correlates, growth ...

Last Updated: 27 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchopulmonary Dysplasia" returned 53 free, full-text review articles on human participants. First 3 results:

Systematic Review of Inhaled Bronchodilator and Corticosteroid Therapies in Infants with Bronchopulmonary Dysplasia: Implications and Future Directions.
 

Author(s): Brian J Clouse, Sudarshan R Jadcherla, Jonathan L Slaughter

Journal:

 

There is much debate surrounding the use of inhaled bronchodilators and corticosteroids for infants with bronchopulmonary dysplasia (BPD).

Last Updated: 4 Feb 2016

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Impaired pulmonary vascular development in bronchopulmonary dysplasia.
 

Author(s): Christopher D Baker, Steven H Abman

Journal: Neonatology. 2015 ;107(4):344-51.

 

Bronchopulmonary dysplasia (BPD), the chronic lung disease associated with preterm birth, results from the disruption of normal pulmonary vascular and alveolar growth. Though BPD was once described as primarily due to postnatal injury from mechanical ventilation and oxygen therapy ...

Last Updated: 5 Jun 2015

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Understanding the Short- and Long-Term Respiratory Outcomes of Prematurity and Bronchopulmonary Dysplasia.
 

Author(s): Jessica Y Islam, Roberta L Keller, Judy L Aschner, Tina V Hartert, Paul E Moore

Journal: Am. J. Respir. Crit. Care Med.. 2015 Jul;192(2):134-56.

 

Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease associated with premature birth that primarily affects infants born at less than 28 weeks' gestational age. BPD is the most common serious complication experienced by premature infants, with more than 8,000 newly diagnosed ...

Last Updated: 16 Jul 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mesenchymal Stem Cell Therapy for Bronchopulmonary Dysplasia in Preterm Babies
 

Status: Not yet recruiting

Condition Summary: Bronchopulmonary Dysplasia

 

Last Updated: 11 May 2015

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Last Updated: 11 Aug 2015

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Last Updated: 22 Mar 2016

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