Bronchopulmonary Dysplasia

Common Name(s)

Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia (BPD) is a chronic lung condition that affects newborn babies, specifically premature and low birth weight babies. Premature infants have fragile, often under developed, lungs that become irritated or injured easily and are in need of a breathing machine. Symptoms to look for in a baby include bluish skin (cyanosis), flaring of nostrils, rapid/shallow breathing, and grunting sounds. Infants with BPD are cared for in the NICU with oxygen therapy/ventilators and proper fluid and nutrient uptake for weeks to months in the hospital. Because these babies are at a greater risk for severe and repeated respiratory infections, it is important to take additional precautions such as limiting contact with those who may be infected by a respiratory virus and washing your hands before touching the baby.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchopulmonary Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchopulmonary Dysplasia" returned 219 free, full-text research articles on human participants. First 3 results:

Association of a vascular endothelial growth factor polymorphism with the development of bronchopulmonary dysplasia in Japanese premature newborns.
 

Author(s): Kazumichi Fujioka, Akio Shibata, Tomoyuki Yokota, Tsubasa Koda, Miwako Nagasaka, Mariko Yagi, Yasuhiro Takeshima, Hideto Yamada, Kazumoto Iijima, Ichiro Morioka

Journal:

 

Our objective was to correlate vascular endothelial growth factor (VEGF) genetic polymorphisms with the risk of bronchopulmonary dysplasia (BPD) development in premature newborns. Fifty-five newborns with BPD (BPD: median gestational age [GA]: 27 weeks, birthweight [BW]: 786 g) ...

Last Updated: 25 Mar 2014

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Mesenchymal stem cells for bronchopulmonary dysplasia: phase 1 dose-escalation clinical trial.
 

Author(s): Yun Sil Chang, So Yoon Ahn, Hye Soo Yoo, Se In Sung, Soo Jin Choi, Won Il Oh, Won Soon Park

Journal: J. Pediatr.. 2014 May;164(5):966-972.e6.

 

To assess the safety and feasibility of allogeneic human umbilical cord blood (hUCB)-derived mesenchymal stem cell (MSC) transplantation in preterm infants.

Last Updated: 18 Apr 2014

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Association between postnatal dexamethasone for treatment of bronchopulmonary dysplasia and brain volumes at adolescence in infants born very preterm.
 

Author(s): Jeanie L Y Cheong, Alice C Burnett, Katherine J Lee, Gehan Roberts, Deanne K Thompson, Stephen J Wood, Alan Connelly, Peter J Anderson, Lex W Doyle,

Journal: J. Pediatr.. 2014 Apr;164(4):737-743.e1.

 

To compare brain volumes in adolescents who were born extremely preterm (<28 weeks gestation) who had received postnatal dexamethasone, and to determine if there was a postnatal dexamethasone dose-response effect on brain volumes.

Last Updated: 21 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchopulmonary Dysplasia" returned 35 free, full-text review articles on human participants. First 3 results:

Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study.
 

Author(s): Wes Onland, Thomas P Debray, Matthew M Laughon, Martijn Miedema, Filip Cools, Lisa M Askie, Jeanette M Asselin, Sandra A Calvert, Sherry E Courtney, Carlo Dani, David J Durand, Neil Marlow, Janet L Peacock, J Jane Pillow, Roger F Soll, Ulrich H Thome, Patrick Truffert, Michael D Schreiber, Patrick Van Reempts, Valentina Vendettuoli, Giovanni Vento, Anton H van Kaam, Karel G Moons, Martin Offringa

Journal:

 

Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Very different models using clinical parameters at an early postnatal age to predict BPD have been developed with little extensive quantitative validation. The objective of this study is to review and validate ...

Last Updated: 30 Dec 2013

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An update on pharmacologic approaches to bronchopulmonary dysplasia.
 

Author(s): Sailaja Ghanta, Kristen Tropea Leeman, Helen Christou

Journal: Semin. Perinatol.. 2013 Apr;37(2):115-23.

 

Bronchopulmonary dysplasia (BPD) is the most prevalent long-term morbidity in surviving extremely preterm infants and is linked to increased risk of reactive airways disease, pulmonary hypertension, post-neonatal mortality, and adverse neurodevelopmental outcomes. BPD affects approximately ...

Last Updated: 15 Apr 2013

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The role of patent ductus arteriosus and its treatments in the development of bronchopulmonary dysplasia.
 

Author(s): Ronald I Clyman

Journal: Semin. Perinatol.. 2013 Apr;37(2):102-7.

 

A persistent left-to-right shunt through a patent ductus arteriosus (PDA) increases the rate of hydrostatic fluid filtration into the lung's interstitium, impairs pulmonary mechanics, and prolongs the need for mechanical ventilation. In preclinical trials, pharmacologic PDA closure ...

Last Updated: 15 Apr 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Role of Anti-Reflux Surgery for Gastroesophageal Reflux Disease in Premature Infants With Bronchopulmonary Dysplasia
 

Status: Recruiting

Condition Summary: Gastroesophageal Reflux Disease; Bronchopulmonary Dysplasia

 

Last Updated: 9 Nov 2010

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Tidal Neonatal NO - is Bronchopulmonary Dysplasia Predictable?
 

Status: Recruiting

Condition Summary: Term Delivery With Preterm Labor, Third Trimester; Term Delivery With Preterm Labor, Unspecified Trimester; Bronchopulmonary Dysplasia

 

Last Updated: 19 Aug 2013

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Last Updated: 5 Feb 2013

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