Bronchopulmonary Dysplasia

Common Name(s)

Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia (BPD) is a chronic lung condition that affects newborn babies, specifically premature and low birth weight babies. Premature infants have fragile, often under developed, lungs that become irritated or injured easily and are in need of a breathing machine. Symptoms to look for in a baby include bluish skin (cyanosis), flaring of nostrils, rapid/shallow breathing, and grunting sounds. Infants with BPD are cared for in the NICU with oxygen therapy/ventilators and proper fluid and nutrient uptake for weeks to months in the hospital. Because these babies are at a greater risk for severe and repeated respiratory infections, it is important to take additional precautions such as limiting contact with those who may be infected by a respiratory virus and washing your hands before touching the baby.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchopulmonary Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchopulmonary Dysplasia" returned 251 free, full-text research articles on human participants. First 3 results:

[Clinical and imaging features of premature infants with different degrees of bronchopulmonary dysplasia].
 

Author(s): Yan-Li Ren, Xiang-Yong Kong, Zhi-Fang Du, Zhi-Chun Feng, Jun-Jin Huang, Jia Chen, Shan Zhang

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2015 May;17(5):440-4.

 

To study the clinical and imaging features of premature infants with different degrees of bronchopulmonary dysplasia (BPD).

Last Updated: 27 May 2015

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Role of serine proteases in the regulation of interleukin-877 during the development of bronchopulmonary dysplasia in preterm ventilated infants.
 

Author(s): Mallinath Chakraborty, Eamon P McGreal, Andrew Williams, Philip L Davies, Wendy Powell, Salima Abdulla, Nikolai N Voitenok, John Hogwood, Elaine Gray, Brad Spiller, Rachel C Chambers, Sailesh Kotecha

Journal:

 

The chemokine interleukin-8 is implicated in the development of bronchopulmonary dysplasia in preterm infants. The 77-amino acid isoform of interleukin-8 (interleukin-877) is a less potent chemoattractant than other shorter isoforms. Although interleukin-877 is abundant in the preterm ...

Last Updated: 5 Dec 2014

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A study of genes encoding cytokines (IL6, IL10, TNF), cytokine receptors (IL6R, IL6ST), and glucocorticoid receptor (NR3C1) and susceptibility to bronchopulmonary dysplasia.
 

Author(s): Johanna M Huusko, Minna K Karjalainen, Mari Mahlman, Ritva Haataja, M Anneli Kari, Sture Andersson, Gergely Toldi, Outi Tammela, Mika Rämet, Pascal M Lavoie, Mikko Hallman,

Journal:

 

Bronchopulmonary dysplasia (BPD) is a common chronic lung disease associated with very preterm birth. The major risk factors include lung inflammation and lung immaturity. In addition, genetic factors play an important role in susceptibility to moderate-to-severe BPD. In this study, ...

Last Updated: 21 Nov 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchopulmonary Dysplasia" returned 49 free, full-text review articles on human participants. First 3 results:

Stem cell therapy for bronchopulmonary dysplasia: bench to bedside translation.
 

Author(s): So Yoon Ahn, Yun Sil Chang, Won Soon Park

Journal: J. Korean Med. Sci.. 2015 May;30(5):509-13.

 

Bronchopulmonary dysplasia (BPD), a chronic lung disease affecting very premature infants, is a major cause of mortality and long-term morbidities despite of current progress in neonatal intensive care medicine. Though there has not been any effective treatment or preventive strategy ...

Last Updated: 1 May 2015

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Pulmonary arterial hypertension associated with bronchopulmonary dysplasia and congenital heart disease in preterm infants. A case report of a preterm infant with recurrent pulmonary hypertension after corrective cardiac surgery and review of the literature.
 

Author(s): Jun Muneuchi, Ayako Kuraoka, Mamie Watanabe, Yoshie Ochiai, Kunitaka Joo

Journal: Int Heart J. 2015 ;56 Suppl():S22-5.

 

In preterm infants with congenital heart disease, concomitant bronchopulmonary dysplasia (BPD) is associated with relatively poor clinical outcomes because of the increased pulmonary vascular resistance and adverse effects of inflammation on the damaged lungs, even after surgery. ...

Last Updated: 19 Mar 2015

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Animal models of bronchopulmonary dysplasia. The preterm and term rabbit models.
 

Author(s): Carl T D'Angio, Rita M Ryan

Journal: Am. J. Physiol. Lung Cell Mol. Physiol.. 2014 Dec;307(12):L959-69.

 

Bronchopulmonary dysplasia (BPD) is an important lung developmental pathophysiology that affects many premature infants each year. Newborn animal models employing both premature and term animals have been used over the years to study various components of BPD. This review describes ...

Last Updated: 16 Dec 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Mesenchymal Stem Cell Therapy for Bronchopulmonary Dysplasia in Preterm Babies
 

Status: Not yet recruiting

Condition Summary: Bronchopulmonary Dysplasia

 

Last Updated: 11 May 2015

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Last Updated: 11 Aug 2015

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Last Updated: 30 Mar 2015

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