Bronchopulmonary Dysplasia

Common Name(s)

Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia (BPD) is a chronic lung condition that affects newborn babies, specifically premature and low birth weight babies. Premature infants have fragile, often under developed, lungs that become irritated or injured easily and are in need of a breathing machine. Symptoms to look for in a baby include bluish skin (cyanosis), flaring of nostrils, rapid/shallow breathing, and grunting sounds. Infants with BPD are cared for in the NICU with oxygen therapy/ventilators and proper fluid and nutrient uptake for weeks to months in the hospital. Because these babies are at a greater risk for severe and repeated respiratory infections, it is important to take additional precautions such as limiting contact with those who may be infected by a respiratory virus and washing your hands before touching the baby.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchopulmonary Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchopulmonary Dysplasia" returned 236 free, full-text research articles on human participants. First 3 results:

A study of genes encoding cytokines (IL6, IL10, TNF), cytokine receptors (IL6R, IL6ST), and glucocorticoid receptor (NR3C1) and susceptibility to bronchopulmonary dysplasia.
 

Author(s): Johanna M Huusko, Minna K Karjalainen, Mari Mahlman, Ritva Haataja, M Anneli Kari, Sture Andersson, Gergely Toldi, Outi Tammela, Mika Rämet, Pascal M Lavoie, Mikko Hallman,

Journal:

 

Bronchopulmonary dysplasia (BPD) is a common chronic lung disease associated with very preterm birth. The major risk factors include lung inflammation and lung immaturity. In addition, genetic factors play an important role in susceptibility to moderate-to-severe BPD. In this study, ...

Last Updated: 21 Nov 2014

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[Expression of TGF-β1 and PAI-1 in premature infants with bronchopulmonary dysplasia].
 

Author(s): Jin-Feng Zhang, Run-Zhong Hunag, Guan-Fen Huang, Wei-Ming Ou, Jian-Feng Li, Jin-Jin Chen

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 Aug;16(8):810-3.

 

To study the expression of transforming growth factor-β1 (TGF-β1) and plasminogen activator inhibitor-1 (PAI-1) and its significance in premature infants with bronchopulmonary dysplasia (BPD).

Last Updated: 21 Aug 2014

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[Association of Ureaplasma urealyticum infection with bronchopulmonary dysplasia in very low birth weight infants with respiratory distress syndrome].
 

Author(s): You Chen, Li-Ya Ma, Yan Huang, Shang-Ming Huang, Shan-Qiu Xiao, Guang-Jin Lu

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 May;16(5):469-72.

 

To study the relationship between Ureaplasma urealyticum (UU) infection in the lower respiratory tract and the incidence of bronchopulmonary dysplasia (BPD) in very low birth weight (VLBW) infants with respiratory distress syndrome (RDS).

Last Updated: 26 May 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchopulmonary Dysplasia" returned 41 free, full-text review articles on human participants. First 3 results:

Assessment of inhibited alveolar-capillary membrane structural development and function in bronchopulmonary dysplasia.
 

Author(s): Shawn K Ahlfeld, Simon J Conway

Journal: Birth Defects Res. Part A Clin. Mol. Teratol.. 2014 Mar;100(3):168-79.

 

Bronchopulmonary dysplasia (BPD) is a chronic lung disease of extreme prematurity and is defined clinically by dependence on supplemental oxygen due to impaired gas exchange. Optimal gas exchange is dependent on the development of a sufficient surface area for diffusion. In the mammalian ...

Last Updated: 24 Mar 2014

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Postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia.
 

Author(s): Vineet Bhandari

Journal: Birth Defects Res. Part A Clin. Mol. Teratol.. 2014 Mar;100(3):189-201.

 

Exposure to hyperoxia, invasive mechanical ventilation, and systemic/local sepsis are important antecedents of postnatal inflammation in the pathogenesis of bronchopulmonary dysplasia (BPD). This review will summarize information obtained from animal (baboon, lamb/sheep, rat and mouse) ...

Last Updated: 24 Mar 2014

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Clinical prediction models for bronchopulmonary dysplasia: a systematic review and external validation study.
 

Author(s): Wes Onland, Thomas P Debray, Matthew M Laughon, Martijn Miedema, Filip Cools, Lisa M Askie, Jeanette M Asselin, Sandra A Calvert, Sherry E Courtney, Carlo Dani, David J Durand, Neil Marlow, Janet L Peacock, J Jane Pillow, Roger F Soll, Ulrich H Thome, Patrick Truffert, Michael D Schreiber, Patrick Van Reempts, Valentina Vendettuoli, Giovanni Vento, Anton H van Kaam, Karel G Moons, Martin Offringa

Journal:

 

Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth. Very different models using clinical parameters at an early postnatal age to predict BPD have been developed with little extensive quantitative validation. The objective of this study is to review and validate ...

Last Updated: 30 Dec 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Tidal Neonatal NO - is Bronchopulmonary Dysplasia Predictable?
 

Status: Recruiting

Condition Summary: Term Delivery With Preterm Labor, Third Trimester; Term Delivery With Preterm Labor, Unspecified Trimester; Bronchopulmonary Dysplasia

 

Last Updated: 19 Aug 2013

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Last Updated: 28 Jan 2015

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Last Updated: 2 Mar 2015

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