Bronchopulmonary Dysplasia

Common Name(s)

Bronchopulmonary Dysplasia

Bronchopulmonary Dysplasia (BPD) is a chronic lung condition that affects newborn babies, specifically premature and low birth weight babies. Premature infants have fragile, often under developed, lungs that become irritated or injured easily and are in need of a breathing machine. Symptoms to look for in a baby include bluish skin (cyanosis), flaring of nostrils, rapid/shallow breathing, and grunting sounds. Infants with BPD are cared for in the NICU with oxygen therapy/ventilators and proper fluid and nutrient uptake for weeks to months in the hospital. Because these babies are at a greater risk for severe and repeated respiratory infections, it is important to take additional precautions such as limiting contact with those who may be infected by a respiratory virus and washing your hands before touching the baby.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchopulmonary Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchopulmonary Dysplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchopulmonary Dysplasia" returned 232 free, full-text research articles on human participants. First 3 results:

A study of genes encoding cytokines (IL6, IL10, TNF), cytokine receptors (IL6R, IL6ST), and glucocorticoid receptor (NR3C1) and susceptibility to bronchopulmonary dysplasia.
 

Author(s): Johanna M Huusko, Minna K Karjalainen, Mari Mahlman, Ritva Haataja, M Anneli Kari, Sture Andersson, Gergely Toldi, Outi Tammela, Mika Rämet, Pascal M Lavoie, Mikko Hallman,

Journal:

 

Bronchopulmonary dysplasia (BPD) is a common chronic lung disease associated with very preterm birth. The major risk factors include lung inflammation and lung immaturity. In addition, genetic factors play an important role in susceptibility to moderate-to-severe BPD. In this study, ...

Last Updated: 21 Nov 2014

Go To URL
[Influencing factors for severity of bronchopulmonary dysplasia in preterm infants].
 

Author(s): Yan Li, Qiu-Fen Wei, Xin-Nian Pan, Dan-Hua Meng, Wei Wei, Qiu-Pin Wu

Journal: Zhongguo Dang Dai Er Ke Za Zhi. 2014 Oct;16(10):1014-8.

 

To explore the influencing factors for the severity of bronchopulmonary dysplasia (BPD) in preterm infants.

Last Updated: 25 Oct 2014

Go To URL
A comparison of KL-6 and Clara cell protein as markers for predicting bronchopulmonary dysplasia in preterm infants.
 

Author(s): Keyi Wang, Xianmei Huang, Hui Lu, Zhiqun Zhang

Journal: Dis. Markers. 2014 ;2014():736536.

 

To evaluate the predictive characteristics of KL-6 and CC16 for bronchopulmonary dysplasia (BPD) in preterm infants, either independently or in combination.

Last Updated: 22 Sep 2014

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchopulmonary Dysplasia" returned 43 free, full-text review articles on human participants. First 3 results:

Pulmonary arterial hypertension associated with bronchopulmonary dysplasia and congenital heart disease in preterm infants. A case report of a preterm infant with recurrent pulmonary hypertension after corrective cardiac surgery and review of the literature.
 

Author(s): Jun Muneuchi, Ayako Kuraoka, Mamie Watanabe, Yoshie Ochiai, Kunitaka Joo

Journal: Int Heart J. 2015 ;56 Suppl():S22-5.

 

In preterm infants with congenital heart disease, concomitant bronchopulmonary dysplasia (BPD) is associated with relatively poor clinical outcomes because of the increased pulmonary vascular resistance and adverse effects of inflammation on the damaged lungs, even after surgery. ...

Last Updated: 19 Mar 2015

Go To URL
A systematic review of randomized controlled trials for the prevention of bronchopulmonary dysplasia in infants.
 

Author(s): K S Beam, S Aliaga, S K Ahlfeld, M Cohen-Wolkowiez, P B Smith, M M Laughon

Journal: J Perinatol. 2014 Sep;34(9):705-10.

 

Bronchopulmonary dysplasia (BPD) is the most common cause of pulmonary morbidity in premature infants and is associated with life-long morbidities. Developing drugs for the prevention of BPD would improve public health. We sought to determine characteristics of favorable randomized ...

Last Updated: 2 Sep 2014

Go To URL
Bronchopulmonary dysplasia: NHLBI Workshop on the Primary Prevention of Chronic Lung Diseases.
 

Author(s): Cindy T McEvoy, Lucky Jain, Barbara Schmidt, Steven Abman, Eduardo Bancalari, Judy L Aschner

Journal: Ann Am Thorac Soc. 2014 Apr;11 Suppl 3():S146-53.

 

Bronchopulmonary dysplasia (BPD) is the most common complication of extreme preterm birth. Infants who develop BPD manifest aberrant or arrested pulmonary development and can experience lifelong alterations in cardiopulmonary function. Despite decades of promising research, primary ...

Last Updated: 23 Apr 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Mesenchymal Stem Cell Therapy for Bronchopulmonary Dysplasia in Preterm Babies
 

Status: Not yet recruiting

Condition Summary: Bronchopulmonary Dysplasia

 

Last Updated: 11 May 2015

Go to URL

Last Updated: 11 Aug 2015

Go to URL

Last Updated: 30 Mar 2015

Go to URL