Invasive lobular carcinoma

Common Name(s)

Invasive lobular carcinoma, Invasive lobular carcinoma, breast cancer

Invasive lobular carcinoma (ILC) is less common than invasive ductal carcinoma and accounts for about 1 in 10 cases of invasive breast cancers. ILC starts in the milk-producing glands, lobules, and can spread to other parts of the body if untreated.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive lobular carcinoma" for support, advocacy or research.

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Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

Last Updated: 21 May 2015

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No Stomach For Cancer

Our mission is to support research and united the caring power of people worldwide affected by stomach cancer. We advance awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provide a support network for affected families, and support research for screening, early detection, treatment, and prevention of stomach cancer.

Last Updated: 23 May 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive lobular carcinoma" for support, advocacy or research.

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Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

http://www.bcconnections.org

Last Updated: 21 May 2015

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No Stomach For Cancer

Our mission is to support research and united the caring power of people worldwide affected by stomach cancer. We advance awareness and education about stomach cancer, including Hereditary Diffuse Gastric Cancer (HDGC), provide a support network for affected families, and support research for screening, early detection, treatment, and prevention of stomach cancer.

http://www.nostomachforcancer.org

Last Updated: 23 May 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Invasive lobular carcinoma" returned 66 free, full-text research articles on human participants. First 3 results:

Expression of autophagy related proteins in invasive lobular carcinoma: comparison to invasive ductal carcinoma.
 

Author(s): Yoon Jin Cha, Yon Hee Kim, Nam Hoon Cho, Ja Seung Koo

Journal:

 

The aim of this study is to compare the expression of autophagy related proteins in invasive lobular carcinoma (ILC) with that of autophagy related proteins in invasive ductal carcinoma (IDC), and to determinate its implication. Tissue microarray containing 114 ILC and 692 IDC was ...

Last Updated: 17 Jul 2014

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Genetic predisposition to in situ and invasive lobular carcinoma of the breast.
 

Author(s): Elinor Sawyer, Rebecca Roylance, Christos Petridis, Mark N Brook, Salpie Nowinski, Efterpi Papouli, Olivia Fletcher, Sarah Pinder, Andrew Hanby, Kelly Kohut, Patricia Gorman, Michele Caneppele, Julian Peto, Isabel Dos Santos Silva, Nichola Johnson, Ruth Swann, Miriam Dwek, Katherine-Anne Perkins, Cheryl Gillett, Richard Houlston, Gillian Ross, Paolo De Ieso, Melissa C Southey, John L Hopper, Elena Provenzano, Carmel Apicella, Jelle Wesseling, Sten Cornelissen, Renske Keeman, Peter A Fasching, Sebastian M Jud, Arif B Ekici, Matthias W Beckmann, Michael J Kerin, Federick Marme, Andreas Schneeweiss, Christof Sohn, Barbara Burwinkel, Pascal Guénel, Therese Truong, Pierre Laurent-Puig, Pierre Kerbrat, Stig E Bojesen, Børge G Nordestgaard, Sune F Nielsen, Henrik Flyger, Roger L Milne, Jose Ignacio Arias Perez, Primitiva Menéndez, Javier Benitez, Hermann Brenner, Aida Karina Dieffenbach, Volker Arndt, Christa Stegmaier, Alfons Meindl, Peter Lichtner, Rita K Schmutzler, Magdalena Lochmann, Hiltrud Brauch, Hans-Peter Fischer, Yon-Dschun Ko, , Heli Nevanlinna, Taru A Muranen, Kristiina Aittomäki, Carl Blomqvist, Natalia V Bogdanova, Thilo Dörk, Annika Lindblom, Sara Margolin, Arto Mannermaa, Vesa Kataja, Veli-Matti Kosma, Jaana M Hartikainen, Georgia Chenevix-Trench, Kconfab Investigators, Diether Lambrechts, Caroline Weltens, Erik Van Limbergen, Sigrid Hatse, Jenny Chang-Claude, Anja Rudolph, Petra Seibold, Dieter Flesch-Janys, Paolo Radice, Paolo Peterlongo, Bernardo Bonanni, Sara Volorio, Graham G Giles, Gianluca Severi, Laura Baglietto, Catriona A McLean, Christopher A Haiman, Brian E Henderson, Fredrick Schumacher, Loic Le Marchand, Jacques Simard, Mark S Goldberg, France Labrèche, Martine Dumont, Vessela Kristensen, Robert Winqvist, Katri Pylkäs, Arja Jukkola-Vuorinen, Saila Kauppila, Irene L Andrulis, Julia A Knight, Gord Glendon, Anna Marie Mulligan, Peter Devillee, Rob A E M Tollenaar, Caroline M Seynaeve, Mieke Kriege, Jonine Figueroa, Stephen J Chanock, Mark E Sherman, Maartje J Hooning, Antoinette Hollestelle, Ans M W van den Ouweland, Carolien H M van Deurzen, Jingmei Li, Kamila Czene, Keith Humphreys, Angela Cox, Simon S Cross, Malcolm W R Reed, Mitul Shah, Anna Jakubowska, Jan Lubinski, Katarzyna Jaworska-Bieniek, Katarzyna Durda, Anthony Swerdlow, Alan Ashworth, Nicholas Orr, Minouk Schoemaker, Fergus J Couch, Emily Hallberg, Anna González-Neira, Guillermo Pita, M Rosario Alonso, Daniel C Tessier, Daniel Vincent, Francois Bacot, Manjeet K Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Alison M Dunning, Per Hall, Doug Easton, Paul Pharoah, Marjanka K Schmidt, Ian Tomlinson, Montserrat Garcia-Closas

Journal:

 

Invasive lobular breast cancer (ILC) accounts for 10-15% of all invasive breast carcinomas. It is generally ER positive (ER+) and often associated with lobular carcinoma in situ (LCIS). Genome-wide association studies have identified more than 70 common polymorphisms that predispose ...

Last Updated: 18 Apr 2014

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A comparison of the clinical outcomes of patients with invasive lobular carcinoma and invasive ductal carcinoma of the breast according to molecular subtype in a Korean population.
 

Author(s): Seung Taek Lim, Jong Han Yu, Heung Kyu Park, Byung In Moon, Byung Kyun Ko, Young Jin Suh

Journal:

 

To investigate the clinicopathological characteristics and the survival outcomes of invasive lobular carcinoma (ILC) patients compared to invasive ductal carcinoma (IDC) patients according to their molecular subtype.

Last Updated: 16 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Invasive lobular carcinoma" returned 3 free, full-text review articles on human participants. First 3 results:

MRI compared to conventional diagnostic work-up in the detection and evaluation of invasive lobular carcinoma of the breast: a review of existing literature.
 

Author(s): Ritse M Mann, Yvonne L Hoogeveen, Johan G Blickman, Carla Boetes

Journal: Breast Cancer Res. Treat.. 2008 Jan;107(1):1-14.

 

The clinical diagnosis and management of invasive lobular carcinoma (ILC) of the breast presents difficulties. Magnetic resonance imaging (MRI) has been proposed as the imaging modality of choice for the evaluation of ILC. Small studies addressing different aspects of MRI in ILC have ...

Last Updated: 28 Nov 2007

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The diagnosis and management of pre-invasive breast disease: pathology of atypical lobular hyperplasia and lobular carcinoma in situ.
 

Author(s): Peter T Simpson, Theodora Gale, Laura G Fulford, Jorge S Reis-Filho, Sunil R Lakhani

Journal: Breast Cancer Res.. 2003 ;5(5):258-62.

 

The term lobular neoplasia refers to a spectrum of lesions featuring atypical lobular hyperplasia and lobular carcinoma in situ (LCIS). The histopathological characteristics of these lesions are well documented. What is less well understood is the management implications of a patient ...

Last Updated: 20 Aug 2003

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[Invasive lobular carcinoma of the breast with a 10-year evolution].
 

Author(s): C R da Fonseca, M M Reis

Journal: Acta Med Port. 1995 Mar;8(3):157-9.

 

The authors present a case of an 82-year-old woman with on invasive lobular carcinoma of the breast (ILC) diagnosed ten years ago in a left axillary adenopathy. Physical and mammographic findings appeared as normal. Some considerations are made about the low incidence, the clinical ...

Last Updated: 6 Dec 1995

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intraoperative Imaging of Breast Cancer With Indocyanine Green
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Invasive Lobular Carcinoma; Ductal Carcinoma

 

Last Updated: 14 Jan 2015

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Caloric Restriction in Treating Patients With Stage 0-I Breast Cancer Undergoing Surgery and Radiation Therapy
 

Status: Recruiting

Condition Summary: Ductal Breast Carcinoma in Situ; Invasive Ductal Breast Carcinoma; Invasive Lobular Breast Carcinoma; Lobular Breast Carcinoma in Situ; Recurrent Breast Cancer; Stage IA Breast Cancer; Stage IB Breast Cancer

 

Last Updated: 5 Feb 2015

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"Phase II Study of PET Guided Neoadjuvant Chemotherapy (NAC) and Oncotype Guided Hormonal Therapy of Breast Cancer"
 

Status: Recruiting

Condition Summary: Infiltrating Duct and Lobular Carcinoma In Situ; Invasive Lobular Breast Carcinoma; Inflammatory Breast Carcinoma

 

Last Updated: 12 Jul 2012

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