Invasive ductal carcinoma

Common Name(s)

Invasive ductal carcinoma, Invasive ductal carcinoma, breast cancer

Invasive ductal carcinoma (IDC) is a type of breast cancer that originates in the milk ducts and spreads to other tissue. Cancers form when a mutation in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis. IDC is the most common breast cancer, and it is also the only type of breast cancer that can be found in men. Many of the risk factors for breast cancer are related to estrogen exposure, such as older age, having children later in life, having few or no children, taking estrogen-containing medications, early menarche (first period), and late menopause. Other risk factors include increased alcohol intake, obesity, and family and individual history of certain types of cancer.

Symptoms of IDC include swelling of the breast, skin irritation (thickening, redness, or scales), nipple or breast pain, and irregular nipple discharge. A biopsy or sample of cells from the affected area can be performed to confirm the presence of cancer. Additional tests should be run to determine the extent and location of disease, and whether the cancer has spread. Often the first place that IDC spreads is to lymph nodes located above the breast and around the armpits. The stage of cancer will be determined based on the tumor size and whether it has spread to nearby lymph nodes or to other organs by metastasis.

Treatment options for IDC include surgery to remove the tumor, radiation therapy, chemotherapy, hormone (endocrine) therapy, and other targeted therapies. If you have been diagnosed with IDC, talk to your doctor about the best treatment options. In addition, a genetic counselor can help discuss inheritance and risks to other family members. Support groups are a good source of information and can connect you with others who have been affected by breast cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

Logo
Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

Last Updated: 21 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

Logo
Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

http://www.bcconnections.org

Last Updated: 21 May 2015

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Invasive ductal carcinoma" returned 258 free, full-text research articles on human participants. First 3 results:

Screen detection of ductal carcinoma in situ and subsequent incidence of invasive interval breast cancers: a retrospective population-based study.
 

Author(s): Stephen W Duffy, Amanda Dibden, Dimitrios Michalopoulos, Judith Offman, Dharmishta Parmar, Jacquie Jenkins, Beverley Collins, Tony Robson, Suzanne Scorfield, Kathryn Green, Clare Hall, Xiao-Hui Liao, Michael Ryan, Fiona Johnson, Guy Stevens, Olive Kearins, Sarah Sellars, Julietta Patnick

Journal: Lancet Oncol.. 2016 Jan;17(1):109-14.

 

The value of screen detection and treatment of ductal carcinoma in situ (DCIS) is a matter of controversy. At present, the extent to which the diagnosis and treatment of DCIS could prevent the occurrence of invasive breast cancer in the future is not clear. We sought to estimate the ...

Last Updated: 13 Jan 2016

Go To URL
Investigation of telomerase activity and apoptosis on invasive ductal carcinoma of the breast using immunohistochemical and Western blot methods.
 

Author(s): B C Simsek, B A Turk, F Ozen, M Tuzcu, M Kanter

Journal: Eur Rev Med Pharmacol Sci. 2015 Aug;19(16):3089-99.

 

Invasive ductal carcinoma (IDC) comprises the largest group of breast cancers. This study aimed to investigate telomerase activity and apoptosis using immunohistochemical and Western blot methods.

Last Updated: 15 Sep 2015

Go To URL
Comparison of 18F-FDG PET/CT for Systemic Staging of Newly Diagnosed Invasive Lobular Carcinoma Versus Invasive Ductal Carcinoma.
 

Author(s): Molly P Hogan, Debra A Goldman, Brittany Dashevsky, Christopher C Riedl, Mithat Gönen, Joseph R Osborne, Maxine Jochelson, Clifford Hudis, Monica Morrow, Gary A Ulaner

Journal: J. Nucl. Med.. 2015 Nov;56(11):1674-80.

 

Although guidelines such as those of the National Comprehensive Cancer Network consider (18)F-FDG PET/CT for systemic staging of newly diagnosed stage III breast cancer patients, factors in addition to stage may influence the utility of PET/CT. Because invasive lobular carcinoma (ILC) ...

Last Updated: 3 Nov 2015

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Invasive ductal carcinoma" returned 10 free, full-text review articles on human participants. First 3 results:

Synchronous bilateral non-Hodgkin's diffuse large B-cell lymphoma of the breast and left breast invasive ductal carcinoma: a case report and review of literature.
 

Author(s): Weihua Liu, Hong Zhu, Xiaoge Zhou

Journal:

 

Lymphoma of the breast is unusual, and synchronous bilateral lymphoma and carcinoma of the breast is extremely rare. We present the case of a 51-year-old woman who found a mass in her left breast. Ultrasound scan findings revealed nodules at the 2 o'clock position in her left breast ...

Last Updated: 17 Nov 2014

Go To URL
Synchronous invasive ductal carcinoma and intravascular large B-cell lymphoma of the breast: a case report and review of the literature.
 

Author(s): Christopher Wei Guang Ho, Sangeeta Mantoo, Chin Hong Lim, Chow Yin Wong

Journal:

 

Primary breast lymphomas (PBLs) represent less than 1% of all breast malignancies. Intravascular large B-cell lymphoma (ILBCL) is a rare, aggressive form of extranodal lymphoma. Breast involvement has only been described in the literature once previously. ILBCL is characterized by ...

Last Updated: 9 Apr 2014

Go To URL
Invasive ductal carcinoma of the breast associated with extensive melanin melanosis: a case report and review of the literature.
 

Author(s): Xiangsheng Zhang, Yu Liang, Huan-You Wang

Journal:

 

Extensive melanosis of breast tissue due to melanin in the absence of involvement by melanoma either primary or secondary has been rarely encountered. Herein we report a first and unique case of extensive macroscopic and microscopic melanosis of mammary parenchyma between carcinoma ...

Last Updated: 3 Apr 2014

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Intraoperative Imaging of Breast Cancer With Indocyanine Green
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Invasive Lobular Carcinoma; Ductal Carcinoma

 

Last Updated: 13 May 2016

Go to URL
Safety and Efficacy Study of the Xoft® Axxent® eBx™ IORT System
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Ductal Carcinoma in Situ

 

Last Updated: 22 Jul 2016

Go to URL
CyberKnife Stereotactic Accelerated Partial Breast Irradiation (SAPBI)
 

Status: Recruiting

Condition Summary: Breast Cancer; DCIS; Invasive Ductal Carcinoma

 

Last Updated: 21 Jun 2016

Go to URL