Invasive ductal carcinoma

Common Name(s)

Invasive ductal carcinoma, Invasive ductal carcinoma, breast cancer

Invasive ductal carcinoma (IDC) is a type of breast cancer that originates in the milk ducts and spreads to other tissue. Cancers form when a mutation in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis. IDC is the most common breast cancer, and it is also the only type of breast cancer that can be found in men. Many of the risk factors for breast cancer are related to estrogen exposure, such as older age, having children later in life, having few or no children, taking estrogen-containing medications, early menarche (first period), and late menopause. Other risk factors include increased alcohol intake, obesity, and family and individual history of certain types of cancer.

Symptoms of IDC include swelling of the breast, skin irritation (thickening, redness, or scales), nipple or breast pain, and irregular nipple discharge. A biopsy or sample of cells from the affected area can be performed to confirm the presence of cancer. Additional tests should be run to determine the extent and location of disease, and whether the cancer has spread. Often the first place that IDC spreads is to lymph nodes located above the breast and around the armpits. The stage of cancer will be determined based on the tumor size and whether it has spread to nearby lymph nodes or to other organs by metastasis.

Treatment options for IDC include surgery to remove the tumor, radiation therapy, chemotherapy, hormone (endocrine) therapy, and other targeted therapies. If you have been diagnosed with IDC, talk to your doctor about the best treatment options. In addition, a genetic counselor can help discuss inheritance and risks to other family members. Support groups are a good source of information and can connect you with others who have been affected by breast cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

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Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

Last Updated: 21 May 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

Logo
Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

http://www.bcconnections.org

Last Updated: 21 May 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Invasive ductal carcinoma" returned 274 free, full-text research articles on human participants. First 3 results:

Comparison of ipsilateral breast tumor recurrence after breast-conserving surgery between ductal carcinoma in situ and invasive breast cancer.
 

Author(s): Young Jin Choi, Young Duck Shin, Young Jin Song

Journal:

 

We aimed to evaluate the differences in the rates and predictive factors for ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery (BCS) between ductal carcinoma in situ (DCIS) and invasive breast cancer. And, we evaluated the impact of IBTR on overall survival ...

Last Updated: 28 Apr 2016

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Anal metastasis as the sentinel and isolated presentation of invasive ductal breast carcinoma.
 

Author(s): C Rengifo, S Titi, J Walls

Journal: Ann R Coll Surg Engl. 2016 May;98(5):e68-70.

 

Breast cancer currently affects 1 in 8 women in the UK during their lifetime. Common sites for breast cancer metastasis include the axillary lymph nodes, bones, lung, liver, brain, soft tissue and adrenal glands. There is well documented evidence detailing breast metastasis to the ...

Last Updated: 18 Apr 2016

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Relationship between the expression of Notch1 and EZH2 and the prognosis of breast invasive ductal carcinoma.
 

Author(s): L Zhao, Q Y Zhang, X Luan, X Huang, S Zhao, H Zhao

Journal:

 

We determined whether the coexpression of Notch1 and EZH2 influences the progression and prognosis of breast invasive ductal carcinoma. Using the χ(2) test, a significant difference was found between high and low expression of Notch1 in terms of lymph node, hormone receptor, and ...

Last Updated: 7 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Invasive ductal carcinoma" returned 10 free, full-text review articles on human participants. First 3 results:

Synchronous bilateral non-Hodgkin's diffuse large B-cell lymphoma of the breast and left breast invasive ductal carcinoma: a case report and review of literature.
 

Author(s): Weihua Liu, Hong Zhu, Xiaoge Zhou

Journal:

 

Lymphoma of the breast is unusual, and synchronous bilateral lymphoma and carcinoma of the breast is extremely rare. We present the case of a 51-year-old woman who found a mass in her left breast. Ultrasound scan findings revealed nodules at the 2 o'clock position in her left breast ...

Last Updated: 17 Nov 2014

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Synchronous invasive ductal carcinoma and intravascular large B-cell lymphoma of the breast: a case report and review of the literature.
 

Author(s): Christopher Wei Guang Ho, Sangeeta Mantoo, Chin Hong Lim, Chow Yin Wong

Journal:

 

Primary breast lymphomas (PBLs) represent less than 1% of all breast malignancies. Intravascular large B-cell lymphoma (ILBCL) is a rare, aggressive form of extranodal lymphoma. Breast involvement has only been described in the literature once previously. ILBCL is characterized by ...

Last Updated: 9 Apr 2014

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Invasive ductal carcinoma of the breast associated with extensive melanin melanosis: a case report and review of the literature.
 

Author(s): Xiangsheng Zhang, Yu Liang, Huan-You Wang

Journal:

 

Extensive melanosis of breast tissue due to melanin in the absence of involvement by melanoma either primary or secondary has been rarely encountered. Herein we report a first and unique case of extensive macroscopic and microscopic melanosis of mammary parenchyma between carcinoma ...

Last Updated: 3 Apr 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy Study of the Xoft® Axxent® eBx™ IORT System
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Ductal Carcinoma in Situ

 

Last Updated: 1 Aug 2016

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Intraoperative Imaging of Breast Cancer With Indocyanine Green
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Invasive Lobular Carcinoma; Ductal Carcinoma

 

Last Updated: 13 May 2016

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