Invasive ductal carcinoma

Common Name(s)

Invasive ductal carcinoma, Invasive ductal carcinoma, breast cancer

Invasive ductal carcinoma (IDC) is a type of breast cancer that originates in the milk ducts and spreads to other tissue. Cancers form when a mutation in DNA causes certain cells to grow out of control, sometimes forming a lump or a tumor. Some of these cancerous cells can break off and spread to other parts of the body where they will continue to grow. This process is known as metastasis. IDC is the most common breast cancer, and it is also the only type of breast cancer that can be found in men. Many of the risk factors for breast cancer are related to estrogen exposure, such as older age, having children later in life, having few or no children, taking estrogen-containing medications, early menarche (first period), and late menopause. Other risk factors include increased alcohol intake, obesity, and family and individual history of certain types of cancer.

Symptoms of IDC include swelling of the breast, skin irritation (thickening, redness, or scales), nipple or breast pain, and irregular nipple discharge. A biopsy or sample of cells from the affected area can be performed to confirm the presence of cancer. Additional tests should be run to determine the extent and location of disease, and whether the cancer has spread. Often the first place that IDC spreads is to lymph nodes located above the breast and around the armpits. The stage of cancer will be determined based on the tumor size and whether it has spread to nearby lymph nodes or to other organs by metastasis.

Treatment options for IDC include surgery to remove the tumor, radiation therapy, chemotherapy, hormone (endocrine) therapy, and other targeted therapies. If you have been diagnosed with IDC, talk to your doctor about the best treatment options. In addition, a genetic counselor can help discuss inheritance and risks to other family members. Support groups are a good source of information and can connect you with others who have been affected by breast cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

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Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

Last Updated: 21 May 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Invasive ductal carcinoma" for support, advocacy or research.

Logo
Bay Area Cancer Connections

We support people touched by breast and ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

http://www.bcconnections.org

Last Updated: 21 May 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Invasive ductal carcinoma" returned 272 free, full-text research articles on human participants. First 3 results:

Expression of Lipid Metabolism-Related Proteins Differs between Invasive Lobular Carcinoma and Invasive Ductal Carcinoma.
 

Author(s): Yoon Jin Cha, Hye Min Kim, Ja Seung Koo

Journal:

 

We comparatively investigated the expression and clinical implications of lipid metabolism-related proteins in invasive lobular carcinoma (ILC) and invasive ductal carcinoma (IDC) of the breast. A total of 584 breast cancers (108 ILC and 476 IDC) were subjected to tissue microarray ...

Last Updated: 26 Jan 2017

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Construction and Validation of a Multi-Institutional Tissue Microarray of Invasive Ductal Carcinoma From Racially and Ethnically Diverse Populations.
 

Author(s): Edward Seijo, Diana Lima, Egiebade Iriabho, Jonas Almeida, Jesus Monico, Margarita Echeverri, Sylvia Gutierrez, Idhaliz Flores, Ji-Hyun Lee, Kate Fisher, William E Grizzle, Gabriel L Sica, Charles Butler, Chindo Hicks, Cathy D Meade, Stephen Olufemi Sodeke, Krzysztof Moroz, Domenico Coppola, Teresita Munoz-Antonia

Journal: Cancer Control. 2016 Oct;23(4):383-389.

 

The scarcity of tissues from racial and ethnic minorities at biobanks poses a scientific constraint to research addressing health disparities in minority populations.

Last Updated: 14 Nov 2016

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Invasive micropapillary carcinoma of the breast had poor clinical characteristics but showed no difference in prognosis compared with invasive ductal carcinoma.
 

Author(s): Guanqiao Li, Shiping Yang, Jia Yao, Zhenping Wang, Guangyu Yao, Mingfeng Liu, Changsheng Ye

Journal:

 

It is controversial for prognosis of invasive micropapillary carcinoma (IMPC) compared with invasive ductal carcinoma (IDC) of the breast. To better understand the difference between IMPC and IDC prognoses, we conducted this retrospective study.

Last Updated: 5 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Invasive ductal carcinoma" returned 11 free, full-text review articles on human participants. First 3 results:

Invasive ductal carcinoma of the breast with osteoclast-like giant cells and clear cell features: a case report of a novel finding and review of the literature.
 

Author(s): Nicole K Zagelbaum, Michael F Ward, Nader Okby, Howard Karpoff

Journal:

 

Osteoclast-like giant cells (OLGCs) are a rare histologic finding within a tumor of the breast. Although there has been discussion as to the pathogenesis and prognosis related to this finding, our understanding of its significance remains inconclusive. Clear cells are another unique ...

Last Updated: 26 Aug 2016

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Synchronous bilateral non-Hodgkin's diffuse large B-cell lymphoma of the breast and left breast invasive ductal carcinoma: a case report and review of literature.
 

Author(s): Weihua Liu, Hong Zhu, Xiaoge Zhou

Journal:

 

Lymphoma of the breast is unusual, and synchronous bilateral lymphoma and carcinoma of the breast is extremely rare. We present the case of a 51-year-old woman who found a mass in her left breast. Ultrasound scan findings revealed nodules at the 2 o'clock position in her left breast ...

Last Updated: 17 Nov 2014

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Synchronous invasive ductal carcinoma and intravascular large B-cell lymphoma of the breast: a case report and review of the literature.
 

Author(s): Christopher Wei Guang Ho, Sangeeta Mantoo, Chin Hong Lim, Chow Yin Wong

Journal:

 

Primary breast lymphomas (PBLs) represent less than 1% of all breast malignancies. Intravascular large B-cell lymphoma (ILBCL) is a rare, aggressive form of extranodal lymphoma. Breast involvement has only been described in the literature once previously. ILBCL is characterized by ...

Last Updated: 9 Apr 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Efficacy Study of the Xoft® Axxent® eBx™ IORT System
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Ductal Carcinoma in Situ

 

Last Updated: 22 Jun 2017

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Intraoperative Imaging of Breast Cancer With Indocyanine Green
 

Status: Recruiting

Condition Summary: Invasive Ductal Carcinoma; Invasive Lobular Carcinoma; Ductal Carcinoma

 

Last Updated: 11 Jun 2017

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Palbociclib and Endocrine Therapy for LObular Breast Cancer Preoperative Study (PELOPS)
 

Status: Recruiting

Condition Summary: Breast Cancer

 

Last Updated: 10 Jan 2017

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