HIV

Common Name(s)

HIV

Human immunodeficiency virus or HIV is a viral infection of the immune system. Acquired immune deficiency disease (AIDS) is the umbrella term used to describe the final stage of an HIV infection. HIV is a sexually transmitted infection, but HIV can also be transmitted by contaminated hypodermic needles and blood transfusions, as well as from mother to child during pregnancy, delivery, and breastfeeding. Early symptoms of an HIV infection include fever, rash, night sweats, headaches, sore throat, fatigue, and a general feeling of having the flu, but many individuals who are HIV positive do not have any symptoms. This is because the virus has a latency stage, also known as the chronic phase. The virus can lay dormant inside your cells for years. HIV is a human retrovirus. The term retrovirus means that the virus can replicate inside a human cell. The retrovirus is an RNA virus; it converts itself into DNA and inserts itself into the cell’s genome. Once it is part of the cell’s genetic code, the virus is then produced by the cell’s replication machinery. Once enough of the virus has been produced within the cell, the cell dies and releases the virus into the body. HIV attacks the cells of your immune system, specifically the CD4 cells. CD4 cells include T helper cells, monocytes, macrophages, and dendritic cells. The virus decreases the number CD4 cells in the body, therefore diminishing the body’s ability to fight infection. Once your number of CD4 cells has fallen below 200 per cubic millimeter of blood, you will be diagnosed with AIDS. There is no cure for an HIV infection or AIDS. There are treatments that can suppress the HIV virus and help to slow the progression of the disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

Last Updated: 20 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

Logo
The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

http://www.thewellproject.org/

Last Updated: 20 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HIV" returned 32923 free, full-text research articles on human participants. First 3 results:

Measuring health literacy among people living with HIV who attend a community-based ambulatory clinic in Puerto Rico.
 

Author(s):

Journal: P R Health Sci J. 2015 Mar;34(1):31-7.

 

Health literacy is an important area for interventions aimed at reducing or eliminating the health disparities of people living with HIV (PLWH). We sought to determine the level of functional health literacy (FHL) and its association with medication adherence, symptoms, and their ...

Last Updated: 10 Apr 2015

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HIV infection and HIV-associated behaviors among persons who inject drugs--20 cities, United States, 2012.
 

Author(s): Michael W Spiller, Dita Broz, Cyprian Wejnert, Lina Nerlander, Gabriela Paz-Bailey, ,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2015 Mar;64(10):270-5.

 

In the United States, an estimated 7% of new diagnoses of human immunodeficiency virus (HIV) infection in 2012 were attributed to injection drug use, and an additional 3% to male-to-male sexual contact and injection drug use. To monitor HIV prevalence and behaviors associated with ...

Last Updated: 20 Mar 2015

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JCV-specific T-cells producing IFN-gamma are differently associated with PmL occurrence in HIV patients and liver transplant recipients.
 

Author(s): Chiara Agrati, Luciano Izzo, Giulia Berno, Eleonora Cimini, Veronica Bordoni, Maria L Giancola, Francesco Baldini, Marco Colasanti, Giuseppe M Ettorre, Paolo Izzo, Federico Pugliese, Marco Angrisani, Pierfrancesco Di Cello, Maria R Capobianchi, Antonio Bolognese

Journal: New Microbiol.. 2015 Jan;38(1):85-9.

 

Aim of this work was to investigate a possible correlation between the frequency of JCV-specific T-cells and PML occurrence in HIV-infected subjects and in liver transplant recipients. A significant decrease of JCV-specific T-cells was observed in HIV-PML subjects, highlighting a ...

Last Updated: 6 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HIV" returned 3226 free, full-text review articles on human participants. First 3 results:

HIV-associated neurocognitive disorders (HAND).
 

Author(s): Daniel Elbirt, Keren Mahlab-Guri, Shira Bezalel-Rosenberg, Harpreet Gill, Malka Attali, Ilan Asher

Journal: Isr. Med. Assoc. J.. 2015 Jan;17(1):54-9.

 

Neurocognitive impairment still occurs in the era of HAART, though its onset appears to be delayed and its severity reduced, while HIV-infected individuals live longer with the infection. HAND defines three categories of disorders according to standardized measures of dysfunction: ...

Last Updated: 5 Mar 2015

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Methicillin-resistant Staphylococcus aureus in HIV patients: risk factors associated with colonization and/or infection and methods for characterization of isolates - a systematic review.
 

Author(s): Dennis de Carvalho Ferreira, Glaucilene Rodrigues da Silva, Fernanda Sampaio Cavalcante, Flavia Lima do Carmo, Leonardo Alexandre Fernandes, Suelen Moreira, Mauro Romero Leal Passos, Ana Paula Vieira Colombo, Katia Regina Netto dos Santos

Journal: Clinics (Sao Paulo). 2014 Nov;69(11):770-6.

 

Staphylococcus aureus is an important cause of infections and HIV-infected individuals are frequently susceptible to this pathogen. The aim of this study was to perform a systematic review to identify both the risk factors associated with colonization/infection by methicillin-resistant ...

Last Updated: 18 Dec 2014

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The relationship between HIV and prevalence of disabilities in sub-Saharan Africa: systematic review (FA).
 

Author(s): Lena Morgon Banks, Maria Zuurmond, Rashida Ferrand, Hannah Kuper

Journal: Trop. Med. Int. Health. 2015 Apr;20(4):411-29.

 

To systematically review evidence on the prevalence and risk of disabilities among children and adults living with HIV in sub-Saharan Africa.

Last Updated: 10 Mar 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma
 

Status: Recruiting

Condition Summary: Kaposi's Sarcoma; HIV+; HIV Positive; AIDS

 

Last Updated: 15 Dec 2014

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Efficiency of the Hepatitis B Sci-B-Vac Vaccine in HIV Positive Patients
 

Status: Not yet recruiting

Condition Summary: HIV

 

Last Updated: 5 Oct 2011

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Enhancing Linkage to HIV Care for Newly Detected HIV-positive Persons in Ukraine
 

Status: Not yet recruiting

Condition Summary: HIV

 

Last Updated: 13 Jan 2015

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