HIV

Common Name(s)

HIV

Human immunodeficiency virus or HIV is a viral infection of the immune system. Acquired immune deficiency disease (AIDS) is the umbrella term used to describe the final stage of an HIV infection. HIV is a sexually transmitted infection, but HIV can also be transmitted by contaminated hypodermic needles and blood transfusions, as well as from mother to child during pregnancy, delivery, and breastfeeding. Early symptoms of an HIV infection include fever, rash, night sweats, headaches, sore throat, fatigue, and a general feeling of having the flu, but many individuals who are HIV positive do not have any symptoms. This is because the virus has a latency stage, also known as the chronic phase. The virus can lay dormant inside your cells for years. HIV is a human retrovirus. The term retrovirus means that the virus can replicate inside a human cell. The retrovirus is an RNA virus; it converts itself into DNA and inserts itself into the cell’s genome. Once it is part of the cell’s genetic code, the virus is then produced by the cell’s replication machinery. Once enough of the virus has been produced within the cell, the cell dies and releases the virus into the body. HIV attacks the cells of your immune system, specifically the CD4 cells. CD4 cells include T helper cells, monocytes, macrophages, and dendritic cells. The virus decreases the number CD4 cells in the body, therefore diminishing the body’s ability to fight infection. Once your number of CD4 cells has fallen below 200 per cubic millimeter of blood, you will be diagnosed with AIDS. There is no cure for an HIV infection or AIDS. There are treatments that can suppress the HIV virus and help to slow the progression of the disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

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The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

Last Updated: 11 Jul 2016

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

Last Updated: 20 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

Logo
The STD Project

Established in April of 2012 during STD Awareness Month, The STD Project is a multi-award-winning independent website and progressive movement eradicating STD stigma by facilitating and encouraging awareness, education, and acceptance through story-telling and resource recommendations. We are taking steps toward modern-day sexual health and prevention by advocating for conscientious and informed decisions.

http://www.thestdproject.com/

Last Updated: 11 Jul 2016

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

http://www.thewellproject.org/

Last Updated: 20 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HIV" returned 45334 free, full-text research articles on human participants. First 3 results:

Clinical and laboratorial features of oral candidiasis in HIV-positive patients.
 

Author(s): Regiane Nogueira Spalanzani, Karine Mattos, Luiza Inahe Marques, Pedro Fernando Diniz Barros, Pamela Iruama Peres Pereira, Anamaria Mello Miranda Paniago, Rinaldo Poncio Mendes, Marilene Rodrigues Chang

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):352-356.

 

We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients.

Last Updated: 31 Dec 1969

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Evaluation of inflammatory biomarkers, carotid intima-media thickness and cardiovascular risk in HIV-1 treatment-naive patients.
 

Author(s): Priscila Valéria do Carmo Carvalho, Júlia Fonseca de Morais Caporali, Érica Leandro Marciano Vieira, Nathalia Sernizon Guimarães, Marise Oliveira Fonseca, Unai Tupinambás

Journal: Rev. Soc. Bras. Med. Trop.. ;51(3):277-283.

 

Mortality among HIV patients is 3-15 times higher than that among the general population. Currently, most deaths are due to non-infectious diseases. Chronic inflammation and adverse events due to antiretroviral therapy play crucial roles in increasing cardiovascular risk (CVR).

Last Updated: 31 Dec 1969

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Incentives and barriers to HIV testing among female sex workers in Ceará.
 

Author(s): Telma Alves Martins, Ligia Kerr, Raimunda Hermelinda Maia Macena, Rosa Salani Mota, Inês Dourado, Ana Maria de Brito, Laetitia Atlani Dualt, Laurent Vidal, Carl Kendall

Journal:

 

Estimating HIV prevalence and describing the incentives and barriers for HIV testing among female sex workers.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HIV" returned 4362 free, full-text review articles on human participants. First 3 results:

People Living With HIV: Implications for Rehabilitation Nurses.
 

Author(s): Joseph D Perazzo, Allison R Webel, Ellen McGough, Joachim Voss

Journal: Rehabil Nurs. ;43(3):167-173.

 

The aim of this study was to present a brief overview of challenges faced by people living with HIV (PLHIV) as they age, to discuss the relevance of HIV to rehabilitation nurses, and to provide evidence-based recommendations for rehabilitation professionals working with PLHIV.

Last Updated: 31 Dec 1969

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Therapeutic Potential of Anti-HIV RNA-loaded Exosomes.
 

Author(s): Yong Qiu, Jing Ma, Yi Zeng

Journal: Biomed. Environ. Sci.. 2018 Mar;31(3):215-226.

 

Last Updated: 31 Dec 1969

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Chronic kidney disease in the global adult HIV-infected population: A systematic review and meta-analysis.
 

Author(s): Udeme E Ekrikpo, Andre P Kengne, Aminu K Bello, Emmanuel E Effa, Jean Jacques Noubiap, Babatunde L Salako, Brian L Rayner, Giuseppe Remuzzi, Ikechi G Okpechi

Journal:

 

The widespread use of antiretroviral therapies (ART) has increased life expectancy in HIV patients, predisposing them to chronic non-communicable diseases including Chronic Kidney Disease (CKD). We performed a systematic review and meta-analysis (PROSPERO registration number CRD42016036246) ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety and Immunogenicity of Clade C ALVAC and gp120 HIV Vaccine
 

Status: Recruiting

Condition Summary: HIV Infections

 

Last Updated: 13 Sep 2017

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Safety and Immune Response to a Clade C DNA HIV Vaccine
 

Status: Recruiting

Condition Summary: HIV Infections

 

Last Updated: 28 Dec 2016

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