HIV

Common Name(s)

HIV

Human immunodeficiency virus or HIV is a viral infection of the immune system. Acquired immune deficiency disease (AIDS) is the umbrella term used to describe the final stage of an HIV infection. HIV is a sexually transmitted infection, but HIV can also be transmitted by contaminated hypodermic needles and blood transfusions, as well as from mother to child during pregnancy, delivery, and breastfeeding. Early symptoms of an HIV infection include fever, rash, night sweats, headaches, sore throat, fatigue, and a general feeling of having the flu, but many individuals who are HIV positive do not have any symptoms. This is because the virus has a latency stage, also known as the chronic phase. The virus can lay dormant inside your cells for years. HIV is a human retrovirus. The term retrovirus means that the virus can replicate inside a human cell. The retrovirus is an RNA virus; it converts itself into DNA and inserts itself into the cell’s genome. Once it is part of the cell’s genetic code, the virus is then produced by the cell’s replication machinery. Once enough of the virus has been produced within the cell, the cell dies and releases the virus into the body. HIV attacks the cells of your immune system, specifically the CD4 cells. CD4 cells include T helper cells, monocytes, macrophages, and dendritic cells. The virus decreases the number CD4 cells in the body, therefore diminishing the body’s ability to fight infection. Once your number of CD4 cells has fallen below 200 per cubic millimeter of blood, you will be diagnosed with AIDS. There is no cure for an HIV infection or AIDS. There are treatments that can suppress the HIV virus and help to slow the progression of the disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

Last Updated: 20 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

Logo
The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

http://www.thewellproject.org/

Last Updated: 20 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HIV" returned 37356 free, full-text research articles on human participants. First 3 results:

Antiretroviral Therapy in Early HIV Infection.
 

Author(s): Jens Lundgren, Abdel G Babiker, James D Neaton

Journal: N. Engl. J. Med.. 2016 Jan;374(4):394.

 

Last Updated: 28 Jan 2016

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Increased Prevalence of Diabetes Mellitus in a Non-Obese Adult Population: HIV-Infected Ethiopians.
 

Author(s): Fruma Tzur, Michal Chowers, Nancy Agmon-Levin, Yoseph A Mekori, Alon Y Hershko

Journal: Isr. Med. Assoc. J.. 2015 Oct;17(10):620-3.

 

Diabetes mellitus (DM) is a metabolic sequel in people infected with HIV, especially following the advent of HAART. This may be a particular concern in immigrants due to lifestyle changes.

Last Updated: 10 Dec 2015

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On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection.
 

Author(s): Jean-Michel Molina, Catherine Capitant, Bruno Spire, Gilles Pialoux, Laurent Cotte, Isabelle Charreau, Cecile Tremblay, Jean-Marie Le Gall, Eric Cua, Armelle Pasquet, François Raffi, Claire Pintado, Christian Chidiac, Julie Chas, Pierre Charbonneau, Constance Delaugerre, Marie Suzan-Monti, Benedicte Loze, Julien Fonsart, Gilles Peytavin, Antoine Cheret, Julie Timsit, Gabriel Girard, Nicolas Lorente, Marie Préau, James F Rooney, Mark A Wainberg, David Thompson, Willy Rozenbaum, Veronique Doré, Lucie Marchand, Marie-Christine Simon, Nicolas Etien, Jean-Pierre Aboulker, Laurence Meyer, Jean-François Delfraissy,

Journal: N. Engl. J. Med.. 2015 Dec;373(23):2237-46.

 

Antiretroviral preexposure prophylaxis has been shown to reduce the risk of human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting results have been reported among studies, probably due to challenges of adherence to a daily regimen.

Last Updated: 3 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HIV" returned 3620 free, full-text review articles on human participants. First 3 results:

How Stigma Surrounding the Use of HIV Preexposure Prophylaxis Undermines Prevention and Pleasure: A Call to Destigmatize "Truvada Whores".
 

Author(s): Sarah K Calabrese, Kristen Underhill

Journal: Am J Public Health. 2015 Oct;105(10):1960-4.

 

Antiretroviral preexposure prophylaxis (PrEP; emtricitabine and tenofovir disoproxil fumarate [Truvada]) prevents HIV without penalizing sexual pleasure, and may even enhance pleasure (e.g., by reducing HIV-related anxiety). However, concern about sexual risk behavior increasing with ...

Last Updated: 11 Sep 2015

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Cerebrospinal fluid analysis in the HIV infection and compartmentalization of HIV in the central nervous system.
 

Author(s): Sérgio Monteiro de Almeida

Journal: Arq Neuropsiquiatr. 2015 Jul;73(7):624-9.

 

The nervous system plays an important role in HIV infection. The purpose of this review is to discuss the indications for cerebrospinal fluid (CSF) analysis in HIV infection in clinical practice. CSF analysis in HIV infection is indicated for the diagnosis of opportunistic infections ...

Last Updated: 23 Jul 2015

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A systematic review of post-migration acquisition of HIV among migrants from countries with generalised HIV epidemics living in Europe: mplications for effectively managing HIV prevention programmes and policy.
 

Author(s): Ibidun Fakoya, Débora Álvarez-del Arco, Melvina Woode-Owusu, Susana Monge, Yaiza Rivero-Montesdeoca, Valerie Delpech, Brian Rice, Teymur Noori, Anastasia Pharris, Andrew J Amato-Gauci, Julia del Amo, Fiona M Burns

Journal:

 

Migrant populations from countries with generalised HIV epidemics make up a significant proportion of all HIV/AIDS cases in many European Union and European Economic Area (EU/EEA) countries, with heterosexual transmission the predominant mode of HIV acquisition. While most of these ...

Last Updated: 18 Jun 2015

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Symptoms, Diagnosis, and Treatment

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There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Efficiency of the Hepatitis B Sci-B-Vac Vaccine in HIV Positive Patients
 

Status: Not yet recruiting

Condition Summary: HIV

 

Last Updated: 5 Oct 2011

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Last Updated: 23 Nov 2015

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Reversing Tissue Fibrosis to Improve Immune Reconstitution in HIV
 

Status: Recruiting

Condition Summary: HIV Infection; HIV Infections

 

Last Updated: 1 Jun 2015

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