HIV

Common Name(s)

HIV

Human immunodeficiency virus or HIV is a viral infection of the immune system. Acquired immune deficiency disease (AIDS) is the umbrella term used to describe the final stage of an HIV infection. HIV is a sexually transmitted infection, but HIV can also be transmitted by contaminated hypodermic needles and blood transfusions, as well as from mother to child during pregnancy, delivery, and breastfeeding. Early symptoms of an HIV infection include fever, rash, night sweats, headaches, sore throat, fatigue, and a general feeling of having the flu, but many individuals who are HIV positive do not have any symptoms. This is because the virus has a latency stage, also known as the chronic phase. The virus can lay dormant inside your cells for years. HIV is a human retrovirus. The term retrovirus means that the virus can replicate inside a human cell. The retrovirus is an RNA virus; it converts itself into DNA and inserts itself into the cell’s genome. Once it is part of the cell’s genetic code, the virus is then produced by the cell’s replication machinery. Once enough of the virus has been produced within the cell, the cell dies and releases the virus into the body. HIV attacks the cells of your immune system, specifically the CD4 cells. CD4 cells include T helper cells, monocytes, macrophages, and dendritic cells. The virus decreases the number CD4 cells in the body, therefore diminishing the body’s ability to fight infection. Once your number of CD4 cells has fallen below 200 per cubic millimeter of blood, you will be diagnosed with AIDS. There is no cure for an HIV infection or AIDS. There are treatments that can suppress the HIV virus and help to slow the progression of the disease.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

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The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

Last Updated: 20 May 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "HIV" for support, advocacy or research.

Logo
The Well Project

The Well Project is a non-profit organization whose mission is to change the course of the HIV/AIDS pandemic through a unique and comprehensive focus on women and girls. The Well Project advocates that every woman and girl should have access to quality, up-to-date information about HIV/AIDS.

http://www.thewellproject.org/

Last Updated: 20 May 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "HIV" returned 33799 free, full-text research articles on human participants. First 3 results:

Fulminant HHV-8 associated Castleman's disease in a non-HIV, Kaposi sarcoma patient with borderline hemophagocytic syndrome.
 

Author(s): Irena Barbarov, Maya Koren-Michowitz, Ginette Schiby, Orith Portnoy, David Livingstone, Gad Segal

Journal: Isr. Med. Assoc. J.. 2015 Apr;17(4):253-5.

 

Last Updated: 4 Jun 2015

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Condom use among people living with HIV/AIDS.
 

Author(s): Sim Sai Tin, Viroj Wiwanitkit

Journal: Ann Afr Med. ;14(3):160.

 

Last Updated: 29 May 2015

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Ideological Anachronism Involving Needle and Syringe Exchange Programs: Lessons From the Indiana HIV Outbreak.
 

Author(s): Josiah D Rich, Eli Y Adashi

Journal: JAMA. 2015 Jul;314(1):23-4.

 

Last Updated: 8 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "HIV" returned 3304 free, full-text review articles on human participants. First 3 results:

Role of PD-1 co-inhibitory pathway in HIV infection and potential therapeutic options.
 

Author(s): Vijayakumar Velu, Ravi Dyavar Shetty, Marie Larsson, Esaki M Shankar

Journal:

 

Virus-specific CD8+ T cells play an important role in controlling viral infections including human immunodeficiency virus (HIV) infection. However, during chronic HIV infection, virus-specific CD8+ T cells undergo functional exhaustion, lose effector functions and fail to control ...

Last Updated: 11 Mar 2015

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HIV-associated neurocognitive disorders (HAND).
 

Author(s): Daniel Elbirt, Keren Mahlab-Guri, Shira Bezalel-Rosenberg, Harpreet Gill, Malka Attali, Ilan Asher

Journal: Isr. Med. Assoc. J.. 2015 Jan;17(1):54-9.

 

Neurocognitive impairment still occurs in the era of HAART, though its onset appears to be delayed and its severity reduced, while HIV-infected individuals live longer with the infection. HAND defines three categories of disorders according to standardized measures of dysfunction: ...

Last Updated: 5 Mar 2015

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Immune reconstitution inflammatory syndrome in HIV and sporotrichosis coinfection: report of two cases and review of the literature.
 

Author(s): Marcelo Rosandiski Lyra, Maria Letícia Fernandes Oliveira Nascimento, Andréa Gina Varon, Maria Inês Fernandes Pimentel, Liliane de Fátima Antonio, Maurício Naoto Saheki, Sandro Javier Bedoya-Pacheco, Antonio Carlos Francesconi do Valle

Journal: Rev. Soc. Bras. Med. Trop.. ;47(6):806-9.

 

We report 2 cases of patients with immune reconstitution inflammatory syndrome (IRIS) associated with cutaneous disseminated sporotrichosis and human immunodeficiency virus (HIV) coinfection. The patients received specific treatment for sporotrichosis. However, after 4 and 5 weeks ...

Last Updated: 28 Jan 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Study to Investigate ALDOXORUBICIN in HIV-infected Subjects With Kaposi's Sarcoma
 

Status: Recruiting

Condition Summary: Kaposi's Sarcoma; HIV+; HIV Positive; AIDS

 

Last Updated: 15 Dec 2014

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Efficiency of the Hepatitis B Sci-B-Vac Vaccine in HIV Positive Patients
 

Status: Not yet recruiting

Condition Summary: HIV

 

Last Updated: 5 Oct 2011

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Enhancing Linkage to HIV Care for Newly Detected HIV-positive Persons in Ukraine
 

Status: Not yet recruiting

Condition Summary: HIV

 

Last Updated: 26 May 2015

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