Y Chromosome Infertility

Common Name(s)

Y Chromosome Infertility

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Y Chromosome Infertility" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Y Chromosome Infertility" returned 14 free, full-text research articles on human participants. First 3 results:

Detection of Y chromosome microdeletions and mitochondrial DNA mutations in male infertility patients.
 

Author(s): A I Güney, D Javadova, D Kırac, K Ulucan, G Koc, D Ergec, H Tavukcu, T Tarcan

Journal:

 

Infertility affects about 10-15% of all couples attempting pregnancy with infertility attributed to the male partner in approximately half of the cases. Proposed causes of male infertility include sperm motility disturbances, Y chromosome microdeletions, chromosomal abnormalities, ...

Last Updated: 22 May 2012

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A frequent Y chromosome b2/b3 subdeletion shows strong association with male infertility in Han-Chinese population.
 

Author(s): B Wu, N X Lu, Y K Xia, A H Gu, C C Lu, W Wang, L Song, S L Wang, H B Shen, X R Wang

Journal: Hum. Reprod.. 2007 Apr;22(4):1107-13.

 

Azoospermia factor c (AZFc) subdeletions were reported to be significant risk factors for spermatogenesis. In this study, we assessed the occurrence of classical AZF deletions and AZFc subdeletions and their impact on male infertility in a Han-Chinese population.

Last Updated: 2 Apr 2007

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A rapid and simple system of detecting deletions on the Y chromosome related with male infertility using multiplex PCR.
 

Author(s): Mayumi Umeno, Toshikatsu Shinka, Youichi Sato, Xin-Jun Yang, Yoshinobu Baba, Teruaki Iwamoto, Yutaka Nakahori

Journal: J. Med. Invest.. 2006 Feb;53(1-2):147-52.

 

Around 10% of males with idiopathic azoospermia or oligozoospermia, which are important causes of male infertility, have partial deletions on the long arm of the Y chromosome. To develop a rapid and accurate detection system for screening major Y deletions found in infertile men, ...

Last Updated: 15 Mar 2006

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Y Chromosome Infertility" returned 9 free, full-text review articles on human participants. First 3 results:

The AZFc region of the Y chromosome: at the crossroads between genetic diversity and male infertility.
 

Author(s): Paulo Navarro-Costa, João Gonçalves, Carlos E Plancha

Journal: Hum. Reprod. Update. ;16(5):525-42.

 

The three azoospermia factor (AZF) regions of the Y chromosome represent genomic niches for spermatogenesis genes. Yet, the most distal region, AZFc, is a major generator of large-scale variation in the human genome. Determining to what extent this variability affects spermatogenesis ...

Last Updated: 10 Aug 2010

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Transmission of male infertility to future generations: lessons from the Y chromosome.
 

Author(s): Sherman J Silber, Sjoerd Repping

Journal: Hum. Reprod. Update. ;8(3):217-29.

 

The introduction of ICSI and testicular sperm extraction (TESE) has allowed many infertile men to father children. The biggest concern about the wide use of these techniques is the health of the resulting offspring, in particular their fertility status. If the spermatogenic defect ...

Last Updated: 24 Jun 2002

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Genetic markers of male infertility: Y chromosome microdeletions and cystic fibrosis transmembrane conductance gene mutations.
 

Author(s): J Sertić, P Cvitković, A Myers, R K Saiki, A Stavljenić Rukavina

Journal: Croat. Med. J.. 2001 Aug;42(4):416-20.

 

Today, approximately 15% of couples have reduced fertility. In most cases the reason is male infertility, usually of genetic origin. Thus, in the context of research in genes involved in reproduction and sex determination, genetic defects in gametogenesis are being extensively studied. ...

Last Updated: 25 Jul 2001

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

RA-2 13-cis Retinoic Acid (Isotretinoin)
 

Status: Not yet recruiting

Condition Summary: Male Infertility; Klinefelter's Syndrome; Y-chromosome Microdeletions

 

Last Updated: 28 Jul 2014

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Clinical Study of Y Chromosome Variants and Infertility
 

Status: Recruiting

Condition Summary: Male Factor Infertility; Female Factor Infertility; Turner Syndrome

 

Last Updated: 21 Jun 2014

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