Chronic Graft versus Host Disease

Common Name(s)

Chronic Graft versus Host Disease

Description for this condition is not yet available.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Graft versus Host Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic Graft versus Host Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic Graft versus Host Disease" returned 450 free, full-text research articles on human participants. First 3 results:

Extrafollicular CD4 T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.
 

Author(s): Ruishu Deng, Christian Hurtz, Qingxiao Song, Chanyu Yue, Gang Xiao, Hua Yu, Xiwei Wu, Markus Muschen, Stephen Forman, Paul J Martin, Defu Zeng

Journal:

 

Chronic graft-versus-host disease (cGVHD) is an autoimmune-like syndrome mediated by pathogenic CD4 T and B cells, but the function of extrafollicular and germinal center CD4 T and B interactions in cGVHD pathogenesis remains largely unknown. Here we show that extrafollicular CD4 ...

Last Updated: 31 Dec 1969

Go To URL
High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype.
 

Author(s): Daisuke Koyama, Makoto Murata, Ryo Hanajiri, Shingo Okuno, Sonoko Kamoshita, Jakrawadee Julamanee, Erina Takagi, Daiki Hirano, Kotaro Miyao, Reona Sakemura, Tatsunori Goto, Fumihiko Hayakawa, Aika Seto, Yukiyasu Ozawa, Koichi Miyamura, Seitaro Terakura, Tetsuya Nishida, Hitoshi Kiyoi

Journal:

 

Regenerating islet-derived protein 3 alpha (REG3A) is a biomarker of lower gastrointestinal graft-versus-host disease (GVHD); however, the biological role of REG3A in the pathophysiology of GVHD is not understood. Here, we examined the association between a single nucleotide polymorphism ...

Last Updated: 31 Dec 1969

Go To URL
Characteristics and risk of chronic graft-versus-host disease of liver in allogeneic hematopoietic stem cell transplant recipients.
 

Author(s): Chien-Ting Chen, Chun-Yu Liu, Yuan-Bin Yu, Chia-Jen Liu, Liang-Tsai Hsiao, Jyh-Pyng Gau, Tzeon-Jye Chiou, Jing-Hwang Liu, Yao-Chung Liu

Journal:

 

Chronic graft-versus-host-disease (cGvHD) is a serious complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Among various organ-specific cGvHD, the cGvHD of liver is less well-characterized. In this study, we applied the National Institutes of Health 2014 ...

Last Updated: 31 Dec 1969

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic Graft versus Host Disease" returned 53 free, full-text review articles on human participants. First 3 results:

Acute and chronic Graft-versus-host disease after hematopoietic stem cell transplantation.
 

Author(s): Vaneuza A M Funke, Maria Claudia Rodrigues Moreira, Afonso Celso Vigorito

Journal: Rev Assoc Med Bras (1992). 2016 Oct;62 SupplĀ 1():44-50.

 

graft-versus-host disease (GVHD) is one of the main complications of hematopoietic stem cell transplantation, affecting about 50% to 80% of the patients. Acute GVHD and its clinical manifestations are discussed in this article, as well as the new NIH criteria for the diagnosis and ...

Last Updated: 31 Dec 1969

Go To URL
Chronic graft-versus-host disease: biological insights from preclinical and clinical studies.
 

Author(s): Kelli P A MacDonald, Geoffrey R Hill, Bruce R Blazar

Journal: Blood. 2017 01;129(1):13-21.

 

With the increasing use of mismatched, unrelated, and granulocyte colony-stimulating factor-mobilized peripheral blood stem cell donor grafts and successful treatment of older recipients, chronic graft-versus-host disease (cGVHD) has emerged as the major cause of nonrelapse mortality ...

Last Updated: 31 Dec 1969

Go To URL
Classification systems for chronic graft-versus-host disease.
 

Author(s): Stephanie J Lee

Journal: Blood. 2017 01;129(1):30-37.

 

Chronic graft versus host disease (GVHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. Clinically, chronic GVHD is a pleiotropic, multiorgan syndrome involving tissue inflammation and fibrosis that often results in permanent organ ...

Last Updated: 31 Dec 1969

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Treatment of Chronic Graft-Versus-Host Disease With Mesenchymal Stromal Cells
 

Status: Recruiting

Condition Summary: Chronic Graft-Versus-Host Disease

 

Last Updated: 11 Nov 2014

Go to URL

Last Updated: 15 Dec 2017

Go to URL
Safety and Efficacy of AMG 592 in Subjects With Steroid Refractory Chronic Graft Versus Host Disease
 

Status: Recruiting

Condition Summary: Chronic Graft Versus Host Disease cGVHD

 

Last Updated: 18 Apr 2018

Go to URL