Pleomorphic Undifferentiated Sarcoma

Common Name(s)

Pleomorphic Undifferentiated Sarcoma

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Pleomorphic Undifferentiated Sarcoma" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Pleomorphic Undifferentiated Sarcoma" returned 22 free, full-text research articles on human participants. First 3 results:

Primary undifferentiated pleomorphic sarcoma of the breast in a young female: a case report.
 

Author(s): Banushree C Srinivasamurthy, Ambedkar Raj Kulandaivelu, Kaushik Saha, Arpita Saha

Journal:

 

Undifferentiated pleomorphic sarcoma is a rare entity and requires extensive immunohistochemical markers to differentiate it from other tumors of the breast.

Last Updated: 16 Jul 2016

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Optimal Percent Myxoid Component to Predict Outcome in High-Grade Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.
 

Author(s): Ann Y Lee, Narasimhan P Agaram, Li-Xuan Qin, Deborah Kuk, Christina Curtin, Murray F Brennan, Samuel Singer

Journal: Ann. Surg. Oncol.. 2016 Mar;23(3):818-25.

 

Myxofibrosarcoma and undifferentiated pleomorphic sarcoma (UPS) are aggressive, genetically complex sarcomas. The minimum myxoid component used as a criterion for myxofibrosarcoma varies widely, so we determined the optimal myxoid component cutpoints for stratifying outcomes of UPS ...

Last Updated: 9 Feb 2016

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Elevated expression of HSP90 and the antitumor effect of an HSP90 inhibitor via inactivation of the Akt/mTOR pathway in undifferentiated pleomorphic sarcoma.
 

Author(s): Hirofumi Bekki, Kenichi Kohashi, Akira Maekawa, Yuichi Yamada, Hidetaka Yamamoto, Katsumi Harimaya, Michiyuki Hakozaki, Kazuki Nabeshima, Yukihide Iwamoto, Yoshinao Oda

Journal:

 

Undifferentiated pleomorphic sarcoma (UPS) is a heterogeneous tumor group, and little is known about molecular target therapy for UPS. Heat shock protein 90 (HSP90) is an expressed chaperone that refolds certain denatured proteins under stress conditions. One of these proteins is ...

Last Updated: 27 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Pleomorphic Undifferentiated Sarcoma" returned 2 free, full-text review articles on human participants. First 3 results:

MFH classification: differentiating undifferentiated pleomorphic sarcoma in the 21st Century.
 

Author(s): Igor Matushansky, Elizabeth Charytonowicz, Joslyn Mills, Sara Siddiqi, Todd Hricik, Carlos Cordon-Cardo

Journal: Expert Rev Anticancer Ther. 2009 Aug;9(8):1135-44.

 

The essence and origin of malignant fibrous histiocytoma (MFH) have been debated for now close to five decades. Originally characterized as a morphologically unique soft-tissue sarcoma subtype of unclear etiology in 1963, with a following 15 years of research only to conclude that ...

Last Updated: 12 Aug 2009

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Primary pleomorphic undifferentiated sarcoma of the kidney: a rare renal tumor.
 

Author(s): Ruchika Gupta, Sampada Gupta, Deepti Aggarwal, Sompal Singh

Journal: Indian J Pathol Microbiol. ;51(4):573-6.

 

Last Updated: 14 Nov 2008

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 18 Apr 2017

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Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Metastatic Angiosarcoma; Metastatic Epithelioid Sarcoma; Metastatic Fibrosarcoma; Metastatic Leiomyosarcoma; Metastatic Liposarcoma; Metastatic Malignant Peripheral Nerve Sheath Tumor; Metastatic Synovial Sarcoma; Metastatic Undifferentiated Pleomorphic Sarcoma; Myxofibrosarcoma; Pleomorphic Rhabdomyosarcoma; Stage III Soft Tissue Sarcoma; Stage IV Soft Tissue Sarcoma; Undifferentiated (Embryonal) Sarcoma

 

Last Updated: 10 Apr 2017

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Sapanisertib or Pazopanib Hydrochloride in Treating Patients With Locally Advanced or Metastatic Sarcoma
 

Status: Recruiting

Condition Summary: High Grade Sarcoma; Metastatic Leiomyosarcoma; Metastatic Malignant Peripheral Nerve Sheath Tumor; Metastatic Synovial Sarcoma; Metastatic Undifferentiated Pleomorphic Sarcoma; Myxofibrosarcoma; Recurrent Leiomyosarcoma; Recurrent Malignant Peripheral Nerve Sheath Tumor; Recurrent Synovial Sarcoma; Recurrent Undifferentiated Pleomorphic Sarcoma; Uterine Corpus Leiomyosarcoma

 

Last Updated: 25 Apr 2017

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