Bronchiolitis Obliterans

Common Name(s)

Bronchiolitis Obliterans

Bronchiolitis obliterans is an inflammatory obstruction of the lung's tiniest airways, the bronchioles. The bronchioles may become damaged and inflamed after inhalation of toxic fumes, as a result of respiratory infections, in association with connective tissue disorders, or after bone marrow or heart-lung transplants. This leads to extensive scarring that blocks the airways, leading to a dry cough, shortness of breath, fatigue and wheezing in the absence of a cold or asthma. While there is no way to reverse the disease, treatments are available to stabilize or slow the progression.  

Another similarly named disease, bronchiolitis obliterans organizing pneumonia, is a completely different disease.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiolitis Obliterans" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiolitis Obliterans" returned 235 free, full-text research articles on human participants. First 3 results:

Complication of post-infectious bronchiolitis obliterans (Swyer-James syndrome).
 

Author(s): Gabriel de Deus Vieira, Alessandra Yukari Yamagishi, Natália Nogueira Vieira, Rebeka Mayara Miranda Dias Fogaça, Thaianne da Cunha Alves, Gisele Megale Brandão Gurgel Amaral, Camila Maciel de Sousa

Journal: Rev Assoc Med Bras. ;61(5):404-6.

 

Swyer-James syndrome is a complication of post-infectious bronchiolitis obliterans that causes inflammation and fibrosis of the bronchial walls. There are two types: asymptomatic, with most cases diagnosed in adults during routine radiological examinations; and symptomatic, most commonly ...

Last Updated: 25 Nov 2015

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A case of bronchiolitis obliterans organizing pneumonia in an HIV-infected Korean patient successfully treated with clarithromycin.
 

Author(s): In Young Jung, Yong Duk Jeon, Mi-Young Ahn, Eunkyong Goag, EunHye Lee, Hea Won Ahn, Jin Young Ahn, Nam Su Ku, June Myung Kim, Jun Yong Choi

Journal:

 

Bronchiolitis obliterans organizing pneumonia (BOOP) is a type of diffuse interstitial lung disease characterized by the pathology of fibroblastic plugs in the lumens of the respiratory bronchioles, alveolar ducts, and alveoli. The occurrence of BOOP in human immunodeficiency virus ...

Last Updated: 23 Jul 2015

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Post-infectious bronchiolitis obliterans and mannose-binding lectin insufficiency in Argentinean children.
 

Author(s): Verónica Giubergia, Maximiliano Salim, Jesica Fraga, Nicolás Castiglioni, Luisa Sen, Claudio Castaños, Andrea Mangano

Journal: Respirology. 2015 Aug;20(6):982-6.

 

Post-infectious bronchiolitis obliterans (PIBO) is a severe disorder following acute lower pulmonary infection in young children, especially caused by adenovirus. Mannose-binding lectin (MBL) deficiency arising from polymorphisms in the coding and non-coding region on the MBL2 gene ...

Last Updated: 16 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiolitis Obliterans" returned 30 free, full-text review articles on human participants. First 3 results:

Systematic review of postradiotherapy bronchiolitis obliterans organizing pneumonia in women with breast cancer.
 

Author(s): Gary R Epler, Eileen M Kelly

Journal: Oncologist. 2014 Dec;19(12):1216-26.

 

Radiation therapy for breast cancer has been implicated in the development of bronchiolitis obliterans organizing pneumonia (BOOP). This inflammatory lung disorder was first noted in 1983, and there have been numerous reports of BOOP occurring in women who have had radiation therapy ...

Last Updated: 6 Dec 2014

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Bronchiolitis obliterans syndrome: the Achilles' heel of lung transplantation.
 

Author(s): S Samuel Weigt, Ariss DerHovanessian, W Dean Wallace, Joseph P Lynch, John A Belperio

Journal: Semin Respir Crit Care Med. 2013 Jun;34(3):336-51.

 

Lung transplantation is a therapeutic option for patients with end-stage pulmonary disorders. Unfortunately, chronic lung allograft dysfunction (CLAD), most commonly manifest as bronchiolitis obliterans syndrome (BOS), continues to be highly prevalent and is the major limitation to ...

Last Updated: 3 Jul 2013

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Bronchoalveolar lavage as a tool to predict, diagnose and understand bronchiolitis obliterans syndrome.
 

Author(s): V E Kennedy, J L Todd, S M Palmer

Journal: Am. J. Transplant.. 2013 Mar;13(3):552-61.

 

Bronchiolitis obliterans syndrome (BOS), a condition of irreversible small airway fibrosis, is the principal factor limiting long-term survival after lung transplantation. Bronchoscopy and bronchoalveolar lavage (BAL), techniques central to lung transplant clinical practice, provide ...

Last Updated: 26 Feb 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Characterization of Bronchiolitis-obliterans Syndrome (BOS) Following Lung Transplantation
 

Status: Recruiting

Condition Summary: Lung Transplantation; Bronchiolitis Obliterans Syndrome

 

Last Updated: 19 Jul 2011

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Dry Powder Inhalation of Cyclosporine A in Lung Transplant Patients With Bronchiolitis Obliterans Syndrome
 

Status: Recruiting

Condition Summary: Lung Transplantation; Bronchiolitis Obliterans

 

Last Updated: 6 Feb 2007

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Last Updated: 11 May 2016

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