Bronchiolitis Obliterans

Common Name(s)

Bronchiolitis Obliterans

Bronchiolitis obliterans is an inflammatory obstruction of the lung's tiniest airways, the bronchioles. The bronchioles may become damaged and inflamed after inhalation of toxic fumes, as a result of respiratory infections, in association with connective tissue disorders, or after bone marrow or heart-lung transplants. This leads to extensive scarring that blocks the airways, leading to a dry cough, shortness of breath, fatigue and wheezing in the absence of a cold or asthma. While there is no way to reverse the disease, treatments are available to stabilize or slow the progression.  

Another similarly named disease, bronchiolitis obliterans organizing pneumonia, is a completely different disease.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Bronchiolitis Obliterans" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Bronchiolitis Obliterans" returned 256 free, full-text research articles on human participants. First 3 results:

Risk Factor and Clinical Outcome of Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation.
 

Author(s): Chin Kook Rhee, Jick Hwan Ha, Jae Ho Yoon, Byung Sik Cho, Woo Sung Min, Hyoung Kyu Yoon, Jong Wook Lee

Journal: Yonsei Med. J.. 2016 Mar;57(2):365-72.

 

The development of bronchiolitis obliterans syndrome (BOS) after allogeneic hematopoietic stem cell transplantation (HSCT) deteriorates patients' quality of life. This study aimed to analyze the prevalence, clinical features, risk factors and prognostic factors of BOS.

Last Updated: 5 Feb 2016

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[Bronchiolitis obliterans associated with Stevens-Johnson syndrome].
 

Author(s): Mariano Fielli, Adrián Ceccato, Alejandra González, Marcelo Villaverde

Journal: Medicina (B Aires). 2015 ;75(6):413-5.

 

Stevens-Johnson syndrome is a severe disease which is characterized by fever and mucocutaneous lesions. It has also been described as a small airway compromise in the form of bronchiolitis obliterans. We report a 22-year-old male patient with Stevens-Johnson syndrome due to antibiotic ...

Last Updated: 28 Dec 2015

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Complication of post-infectious bronchiolitis obliterans (Swyer-James syndrome).
 

Author(s): Gabriel de Deus Vieira, Alessandra Yukari Yamagishi, Natália Nogueira Vieira, Rebeka Mayara Miranda Dias Fogaça, Thaianne da Cunha Alves, Gisele Megale Brandão Gurgel Amaral, Camila Maciel de Sousa

Journal: Rev Assoc Med Bras (1992). ;61(5):404-6.

 

Swyer-James syndrome is a complication of post-infectious bronchiolitis obliterans that causes inflammation and fibrosis of the bronchial walls. There are two types: asymptomatic, with most cases diagnosed in adults during routine radiological examinations; and symptomatic, most commonly ...

Last Updated: 25 Nov 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Bronchiolitis Obliterans" returned 31 free, full-text review articles on human participants. First 3 results:

Systematic review of postradiotherapy bronchiolitis obliterans organizing pneumonia in women with breast cancer.
 

Author(s): Gary R Epler, Eileen M Kelly

Journal: Oncologist. 2014 Dec;19(12):1216-26.

 

Radiation therapy for breast cancer has been implicated in the development of bronchiolitis obliterans organizing pneumonia (BOOP). This inflammatory lung disorder was first noted in 1983, and there have been numerous reports of BOOP occurring in women who have had radiation therapy ...

Last Updated: 6 Dec 2014

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Bronchiolitis obliterans syndrome: the Achilles' heel of lung transplantation.
 

Author(s): S Samuel Weigt, Ariss DerHovanessian, W Dean Wallace, Joseph P Lynch, John A Belperio

Journal: Semin Respir Crit Care Med. 2013 Jun;34(3):336-51.

 

Lung transplantation is a therapeutic option for patients with end-stage pulmonary disorders. Unfortunately, chronic lung allograft dysfunction (CLAD), most commonly manifest as bronchiolitis obliterans syndrome (BOS), continues to be highly prevalent and is the major limitation to ...

Last Updated: 3 Jul 2013

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Bronchoalveolar lavage as a tool to predict, diagnose and understand bronchiolitis obliterans syndrome.
 

Author(s): V E Kennedy, J L Todd, S M Palmer

Journal: Am. J. Transplant.. 2013 Mar;13(3):552-61.

 

Bronchiolitis obliterans syndrome (BOS), a condition of irreversible small airway fibrosis, is the principal factor limiting long-term survival after lung transplantation. Bronchoscopy and bronchoalveolar lavage (BAL), techniques central to lung transplant clinical practice, provide ...

Last Updated: 26 Feb 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Microparticles and Bronchiolitis Obliterans Syndrome
 

Status: Recruiting

Condition Summary: Bronchiolitis Obliterans

 

Last Updated: 27 May 2015

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Last Updated: 22 Oct 2016

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Lung Function, LCI, Bronchial Inflammation and Epigenetics of Patients With BO
 

Status: Recruiting

Condition Summary: Bronchiolitis Obliterans

 

Last Updated: 9 Dec 2015

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