Transient ischemic attack

Common Name(s)

Transient ischemic attack

A stroke occurs when the blood flow to the brain is interrupted or cut-off. When this happens, the affected area of the brain does not receive the oxygen and nutrients that it needs. A transient ischemic attack (TIA) is sometimes referred to as a “mini-stroke” or a “warning stroke”. Like a stroke, a TIA is caused by the formation of a blood clot that interrupts or cuts off blood flow to the brain. The difference between a TIA and a stroke is that in a TIA, the interruption in blood flow is only temporary and there is usually no permanent injury to the brain. A TIA lasts about a minute on average, and usually no longer than five minutes.

The symptoms of a TIA can include sudden onset of weakness, numbness, or paralysis in a body part, slurred speech, blurred vision, loss of vision, and loss of coordination. The most common cause of a TIA is the buildup of cholesterol in the arteries, which causes a small blood clot. TIA’s are called “warning strokes” because one in three people who experience a TIA will later experience a stroke. If you believe that you are having a TIA, you should seek medical help immediately. If you have had a TIA, there are steps that you can take to lower your risk of stroke. These steps include: working to lower cholesterol levels, quitting smoking, engaging in regular physical activity, improving nutrition, limiting alcohol intake, and stopping any illicit drug use. Support groups are available for more resources and information.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Transient ischemic attack" for support, advocacy or research.

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Transient ischemic attack" returned 444 free, full-text research articles on human participants. First 3 results:

Long-term morbidity and mortality in patients without early complications after stroke or transient ischemic attack.
 

Author(s): Jodi D Edwards, Moira K Kapral, Jiming Fang, Richard H Swartz

Journal: CMAJ. 2017 Jul;189(29):E954-E961.

 

Secondary prevention after stroke and transient ischemic attack (TIA) has focused on high early risk of recurrence, but survivors of stroke can have substantial long-term morbidity and mortality. We quantified long-term morbidity and mortality for patients who had no early complications ...

Last Updated: 25 Jul 2017

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Clinical Correlates, Ethnic Differences, and Prognostic Implications of Perivascular Spaces in Transient Ischemic Attack and Ischemic Stroke.
 

Author(s): Kui-Kai Lau, Linxin Li, Caroline E Lovelock, Giovanna Zamboni, Tsz-Tai Chan, Man-Fung Chiang, Kin-Ting Lo, Wilhelm Küker, Henry Ka-Fung Mak, Peter M Rothwell

Journal: Stroke. 2017 Jun;48(6):1470-1477.

 

Perivascular spaces (PVSs) are considered markers of small vessel disease. However, their long-term prognostic implications in transient ischemic attack/ischemic stroke patients are unknown. Ethnic differences in PVS prevalence are also unknown.

Last Updated: 12 May 2017

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(18)F-Fluoride and (18)F-Fluorodeoxyglucose Positron Emission Tomography After Transient Ischemic Attack or Minor Ischemic Stroke: Case-Control Study.
 

Author(s): Alex T Vesey, William S A Jenkins, Agnese Irkle, Alastair Moss, Greg Sng, Rachael O Forsythe, Tim Clark, Gemma Roberts, Alison Fletcher, Christophe Lucatelli, James H F Rudd, Anthony P Davenport, Nicholas L Mills, Rustam Al-Shahi Salman, Martin Dennis, William N Whiteley, Edwin J R van Beek, Marc R Dweck, David E Newby

Journal: Circ Cardiovasc Imaging. 2017 Mar;10(3):.

 

Combined positron emission tomography (PET) and computed tomography (CT) can assess both anatomy and biology of carotid atherosclerosis. We sought to assess whether (18)F-fluoride or (18)F-fluorodeoxyglucose can identify culprit and high-risk carotid plaque.

Last Updated: 15 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Transient ischemic attack" returned 31 free, full-text review articles on human participants. First 3 results:

Is Transient Ischemic Attack a Medical Emergency? An Evidence-Based Analysis.
 

Author(s): S Sehatzadeh

Journal:

 

Transient ischemic attack (TIA) is a brief episode of dysfunction in a confined area of the brain. The risk of stroke following TIA is approximately 4% within the first 2 days and 9% within the first month. Therefore, early diagnosis and treatment is critical to reduce mortality and ...

Last Updated: 11 Sep 2015

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Long-Term Antiplatelet Mono- and Dual Therapies After Ischemic Stroke or Transient Ischemic Attack: Network Meta-Analysis.
 

Author(s): Wuxiang Xie, Fanfan Zheng, Baoliang Zhong, Xiaoyu Song

Journal:

 

The latest guidelines do not make clear recommendations on the selection of antiplatelet therapies for long-term secondary prevention of stroke. We aimed to integrate the available evidence to create hierarchies of the comparative efficacy and safety of long-term antiplatelet therapies ...

Last Updated: 25 Aug 2015

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An update on brain imaging in transient ischemic attack.
 

Author(s): R Souillard-Scemama, M Tisserand, D Calvet, D Jumadilova, S Lion, G Turc, M Edjlali, C Mellerio, C Lamy, O Naggara, J-F Meder, C Oppenheim

Journal: J Neuroradiol. 2015 Feb;42(1):3-11.

 

Neuroimaging is critical in the evaluation of patients with transient ischemic attack (TIA) and MRI is the recommended modality to image an ischemic lesion. The presence of a diffusion (DWI) lesion in a patient with transient neurological symptoms confirms the vascular origin of the ...

Last Updated: 2 Mar 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prevention of Ischemic Conditions in Non-disabling Stroke/Transient Ischemic Attack With Remote Ischemic Conditioning
 

Status: Recruiting

Condition Summary: Transient Ischemic Attack; Non-disabling Stroke

 

Last Updated: 21 Jul 2017

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Dabigatran Following Transient Ischemic Attack and Minor Stroke
 

Status: Recruiting

Condition Summary: Transient Ischemic Attack; Minor Ischemic Stroke

 

Last Updated: 22 Nov 2016

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Psychoeducation for Transient Ischaemic Attack and Minor Stroke
 

Status: Recruiting

Condition Summary: Transient Ischaemic Attack; Stroke

 

Last Updated: 30 Nov 2016

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