Rhabdomyolysis

Common Name(s)

Rhabdomyolysis

Rhabdomyolysis is the breakdown of muscle and the release of muscle cell contents into the bloodstream. Rhabdomyolysis can be caused by genetic or environmental factors. Environmental factors that may cause rhabdomyolysis include crushing trauma, long surgeries, extreme temperatures, or severe muscle strain such as after a marathon or other athletic event. Other causes include severe dehydration, infection, drug use, and seizures. Genetic disorders such as those causing a reduction in muscle enzymes may also lead to rhabdomyolysis. The risk of rhabdomyolysis may be reduced by proper hydration after workout or injury.

Affected individuals may notice dark red or brown urine due to the excretion of muscle breakdown products. Other symptoms of rhabdomyolysis include vomiting, confusion, muscle aches, weakness, low blood pressure, and a rapid heart rate. In severe cases, complications such as permanent kidney damage may occur.

While some individuals may experience the symptoms described above, milder cases are often asymptomatic and later discovered on blood tests. Medications may be used to regulate urine output, and fluid may be given to restore electrolyte levels and prevent shock and kidney damage. Dialysis may be required to remove muscle breakdown products from the blood in individuals with poor kidney function. If you or your child has been diagnosed with rhabdomyolysis, talk to your doctor about the most current treatment options.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Rhabdomyolysis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Rhabdomyolysis" returned 480 free, full-text research articles on human participants. First 3 results:

Fatal Rhabdomyolysis Caused by Morganella morganii in a Patient with Multiple Myeloma.
 

Author(s): Osamu Imataki, Makiko Uemura

Journal: Intern. Med.. 2017 ;56(3):369-371.

 

A 64-year-old Japanese man with multiple myeloma was admitted to our institute due to fever and hypotension. He had received multiple courses of chemotherapy just before his febrile episode. Blood culturing detected Morganella morganii. At the time of the diagnosis, his laboratory ...

Last Updated: 3 Feb 2017

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Rapid Diagnosis of Rhabdomyolysis with Point-of-Care Ultrasound.
 

Author(s): Alicia Nassar, Richard Talbot, Ashley Grant, Charlotte Derr

Journal: West J Emerg Med. 2016 Nov;17(6):801-804.

 

It is important to rapidly diagnosis and treat rhabdomyolysis in order to decrease morbidity and mortality. To date there are no reports in the emergency medicine literature on the use of point-of-care ultrasound in the diagnosis of rhabdomyolysis. This unique case describes how ultrasound ...

Last Updated: 11 Nov 2016

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Sickle Cell Trait and Rhabdomyolysis among U.S. Army Soldiers.
 

Author(s): D Alan Nelson, Patricia A Deuster, Lianne M Kurina

Journal: N. Engl. J. Med.. 2016 10;375(17):1696.

 

Last Updated: 26 Oct 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Rhabdomyolysis" returned 45 free, full-text review articles on human participants. First 3 results:

Fatal endocarditis with methicilin-sensible Staphylococcus aureus and major complications: rhabdomyolysis, pericarditis, and intracerebral hematoma: A case report and review of the literature.
 

Author(s): Anca Meda Georgescu, Leonard Azamfirei, Krisztina Szalman, Edit Szekely

Journal: Medicine (Baltimore). 2016 Oct;95(41):e5125.

 

Over the last decades Staphylococcus aureus (SA) has become the dominant etiology of native valve infective endocarditis, with the community-acquired methicillin-sensible Staphylococcus aureus (CA-MSSA) strains being the prevailing type.

Last Updated: 14 Oct 2016

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Serotonin Syndrome Induced by Combined Use of Mirtazapine and Olanzapine Complicated with Rhabdomyolysis, Acute Renal Failure, and Acute Pulmonary Edema-A Case Report.
 

Author(s): Chi-Shun Wu, Show-Hwa Tong, Cheung-Ter Ong, Sheng-Feng Sung

Journal: Acta Neurol Taiwan. 2015 Dec;24(4):117-21.

 

Serotonin syndrome is a potentially life-threatening complication of serotonergic agents. Although mirtazapine is a relatively safe antidepressant and has a comparatively low incidence of side effects, it still could induce serotonin syndrome.

Last Updated: 23 Jun 2016

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Challenging Return to Play Decisions: Heat Stroke, Exertional Rhabdomyolysis, and Exertional Collapse Associated With Sickle Cell Trait.
 

Author(s): Chad A Asplund, Francis G O'Connor

Journal: Sports Health. ;8(2):117-25.

 

Sports medicine providers frequently return athletes to play after sports-related injuries and conditions. Many of these conditions have guidelines or medical evidence to guide the decision-making process. Occasionally, however, sports medicine providers are challenged with complex ...

Last Updated: 20 Feb 2016

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Exertional Rhabdomyolysis- Characterization of Prediction Tests for Return to Duty
 

Status: Not yet recruiting

Condition Summary: Rhabdomyolysis

 

Last Updated: 14 Jul 2015

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Support for the Rhabdomyolysis in an Emergency Department
 

Status: Not yet recruiting

Condition Summary: Rhabdomyolysis

 

Last Updated: 6 Sep 2016

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The Effect of Remote Ischemic Preconditioning on Physical Performance and Exertional Rhabdomyolysis
 

Status: Not yet recruiting

Condition Summary: Physical Performance; Rhabdomyolysis

 

Last Updated: 23 Dec 2015

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