Serotonin Syndrome

Common Name(s)

Serotonin Syndrome

Description for this condition is not yet available.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Serotonin Syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Serotonin Syndrome" returned 108 free, full-text research articles on human participants. First 3 results:

Telotristat etiprate, a novel serotonin synthesis inhibitor, in patients with carcinoid syndrome and diarrhea not adequately controlled by octreotide.
 

Author(s): Matthew H Kulke, Thomas O'Dorisio, Alexandria Phan, Emily Bergsland, Linda Law, Phillip Banks, Joel Freiman, Kenny Frazier, Jessica Jackson, James C Yao, Larry Kvols, Pablo Lapuerta, Brian Zambrowicz, Douglas Fleming, Arthur Sands

Journal: Endocr. Relat. Cancer. 2014 Oct;21(5):705-14.

 

Serotonin produced by neuroendocrine tumors is believed to be a principal cause of the diarrhea in carcinoid syndrome. We assessed the safety and efficacy of telotristat etiprate, an oral serotonin synthesis inhibitor, in patients with diarrhea associated with carcinoid syndrome. ...

Last Updated: 12 Aug 2014

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DNA hypermethylation of the serotonin receptor type-2A gene is associated with a worse response to a weight loss intervention in subjects with metabolic syndrome.
 

Author(s): Aurora Perez-Cornago, Maria L Mansego, María Angeles Zulet, José Alfredo Martinez

Journal:

 

Understanding the regulation of gene activities depending on DNA methylation has been the subject of much recent study. However, although polymorphisms of the HTR2A gene have been associated with both obesity and psychiatric disorders, the role of HTR2A gene methylation in these illnesses ...

Last Updated: 25 Jun 2014

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Platelet serotonin concentration and clinical status in alcohol withdrawal syndrome, preliminary results.
 

Author(s): Sergio G Llinás, Antonio J Caballero, Julio C Peñalver, Rodolfo Valdés

Journal: MEDICC Rev. 2014 Jan;16(1):37-42.

 

Alcohol withdrawal syndrome is an important problem for management of alcoholism. It is known that alcohol alters the function of neurotransmitters such as serotonin, but our review found no studies associating serotonin concentration changes with patient clinical status during detoxification. ...

Last Updated: 3 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Serotonin Syndrome" returned 18 free, full-text review articles on human participants. First 3 results:

The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies.
 

Author(s): Zhi-Feng Zhang, Zhi-Jun Duan, Li-Xia Wang, Dong Yang, Gang Zhao, Lin Zhang

Journal:

 

The results of previous studies assessing the association between the 5-HTTLPR polymorphism of serotonin transporter gene and irritable bowel syndrome (IBS) are inconsistent. The aim of this study was to clarify the association between the 5-HTTLPR mutation and the presence of IBS ...

Last Updated: 18 Feb 2014

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Animal models of the serotonin syndrome: a systematic review.
 

Author(s): Robert Haberzettl, Bettina Bert, Heidrun Fink, Meredith A Fox

Journal: Behav. Brain Res.. 2013 Nov;256():328-45.

 

The serotonin syndrome (SS) is a potentially life-threatening disorder in humans which is induced by ingestion of an overdose or by combination of two or more serotonin (5-HT)-enhancing drugs. In animals, acute administration of direct and indirect 5-HT agonists also leads to a set ...

Last Updated: 1 Nov 2013

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Serotonin gene variants are unlikely to play a significant role in the pathogenesis of the sudden infant death syndrome.
 

Author(s): David S Paterson

Journal: Respir Physiol Neurobiol. 2013 Nov;189(2):301-14.

 

Sudden infant death syndrome (SIDS) is defined as the sudden and unexpected death of an infant less than 12 months of age that is related to a sleep period and remains unexplained after a complete autopsy, death scene investigation, and review of the clinical history. The cause of ...

Last Updated: 28 Oct 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Telotristat Etiprate - Expanded Treatment for Patients With Carcinoid Syndrome Symptoms
 

Status: Recruiting

Condition Summary: Carcinoid Syndrome

 

Last Updated: 11 Jun 2015

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Regorafenib in Treating Patients With Advanced or Metastatic Neuroendocrine Tumors
 

Status: Not yet recruiting

Condition Summary: Gastrinoma; Glucagonoma; Insulinoma; Metastatic Gastrointestinal Carcinoid Tumor; Pancreatic Polypeptide Tumor; Pulmonary Carcinoid Tumor; Recurrent Gastrointestinal Carcinoid Tumor; Recurrent Islet Cell Carcinoma; Somatostatinoma

 

Last Updated: 25 Mar 2015

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Radiolabeled Octreotide in Treating Children With Advanced or Refractory Solid Tumors
 

Status: Recruiting

Condition Summary: Brain and Central Nervous System Tumors; Gastrointestinal Carcinoid Tumor; Islet Cell Tumor; Neuroblastoma; Pheochromocytoma; Sarcoma; Unspecified Childhood Solid Tumor, Protocol Specific

 

Last Updated: 1 Feb 2011

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