Uveitis

Common Name(s)

Uveitis

Uveitis is inflammation of the middle layer of the eye called the uvea. The uvea consists of the layer and structures beneath the white of the eye. The uvea is made up of the iris, the choroid layer, and the ciliary body. The iris is the colored part of the eye, the choroid layer is the layer of blood vessels and connective tissue, and the ciliary body is the structure in the eye that releases the transparent liquid in the eye. The cause of uveitis is unknown but may be associated with infections, injury, inflammatory and autoimmune disorders, and certain cancers that can affect the eye. Symptoms include eye pain and redness, blurred vision, seeing floaters, light sensitivity, decreased vision, and a whitish area on the inside of the lower part of the iris.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveitis" returned 746 free, full-text research articles on human participants. First 3 results:

Levels of blood CD1c+ mDC1 and CD1chi mDC1 subpopulation reflect disease activity in noninfectious uveitis.
 

Author(s): Ping Chen, William Tucker, Susan Hannes, Baoying Liu, Han Si, Ankur Gupta, Richard W J Lee, H Nida Sen, Robert B Nussenblatt

Journal:

 

Myeloid dendritic cells (mDCs) play an important role in autoimmune diseases. However, the role of blood CD1c(+) myeloid dendritic cells 1 (mDC1s), the subset of human blood mDCs, is not well understood in noninfectious uveitis.

Last Updated: 14 Jan 2015

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Polyuric kidneys and uveitis: an oculorenal syndrome.
 

Author(s): Mahmoud Kamel, Bijin Thajudeen, Erika Bracamonte, Amy Sussman, Yeong-Hau H Lien

Journal:

 

Tubulointerstitial nephritis and uveitis syndrome (TINU syndrome) is a diagnosis of exclusion based on the presence of uveitis and acute tubulointerstitial nephritis in the absence of other disease entities known to cause both of these disorders. The proximal tubule is frequently ...

Last Updated: 30 Nov 2014

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Intraocular levels of interleukin 17A (IL-17A) and IL-10 as respective determinant markers of toxoplasmosis and viral uveitis.
 

Author(s): Arnaud Sauer, Odile Villard, Catherine Creuzot-Garcher, Christophe Chiquet, Jean-Paul Berrod, Claude Speeg-Schatz, Tristan Bourcier, Ermanno Candolfi

Journal: Clin. Vaccine Immunol.. 2015 Jan;22(1):72-8.

 

Uveitis is a potentially blinding inflammatory disease. Thirty to 50% of uveitis cases are considered idiopathic. The present study sought to determine the intraocular cytokine patterns in the different etiological types of uveitis in order to better understand their immunological ...

Last Updated: 31 Dec 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveitis" returned 86 free, full-text review articles on human participants. First 3 results:

Immunopharmacotherapy of non-infectious uveitis: where do we stand?
 

Author(s): Rupesh Agrawal, Cecilia Lee, Sumita Phatak, Carlos Pavesio

Journal: Expert Opin Biol Ther. 2014 Dec;14(12):1719-22.

 

With ever-evolving concept of personalised medicine backed up with specific biomarkers for ocular inflammatory disease, there is a sudden surge of using biologics in non-infectious recalcitrant posterior uveitis. Have we understood these biologic agents enough to embark on this long ...

Last Updated: 10 Nov 2014

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A systematic approach to emergencies in uveitis.
 

Author(s): Hassan A Al-Dhibi, Ammar M Al-Mahmood, J Fernando Arevalo

Journal: Middle East Afr J Ophthalmol. ;21(3):251-8.

 

Uveitis is a common cause of preventable blindness although it is consider a sight-threatening condition particularly in cases with posterior segment inflammation. To deal with emergency conditions in uveitis, we must aware of the essential signs and symptoms that reflect a true uveitic ...

Last Updated: 7 Aug 2014

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Immune recovery uveitis: pathogenesis, clinical symptoms, and treatment.
 

Author(s): Beata Urban, Alina Bakunowicz-Ɓazarczyk, Marta Michalczuk

Journal: Mediators Inflamm.. 2014 ;2014():971417.

 

IRU is the most common form of immune reconstitution inflammatory syndrome in HIV-infected patients with cytomegalovirus retinitis who are receiving highly active antiretroviral therapy (HAART). Among patients with CMV in the HAART era, immune recovery may be associated with a greater ...

Last Updated: 4 Aug 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis
 

Status: Recruiting

Condition Summary: Uveitis; Macular Edema; Uveitis, Posterior; Uveitis, Anterior; Panuveitis; Uveitis, Intermediate

 

Last Updated: 26 Mar 2015

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Sirolimus as Therapeutic Approach to Uveitis
 

Status: Recruiting

Condition Summary: Uveitis; Intermediate Uveitis; Posterior Uveitis; Panuveitis

 

Last Updated: 25 May 2010

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Intravitreal Sirolimus as Therapeutic Approach to Uveitis
 

Status: Not yet recruiting

Condition Summary: Uveitis; Intermediate Uveitis; Posterior Uveitis; Panuveitis

 

Last Updated: 20 Jan 2011

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