Uveitis

Common Name(s)

Uveitis

Uveitis is inflammation of the middle layer of the eye called the uvea. The uvea consists of the layer and structures beneath the white of the eye. The uvea is made up of the iris, the choroid layer, and the ciliary body. The iris is the colored part of the eye, the choroid layer is the layer of blood vessels and connective tissue, and the ciliary body is the structure in the eye that releases the transparent liquid in the eye. The cause of uveitis is unknown but may be associated with infections, injury, inflammatory and autoimmune disorders, and certain cancers that can affect the eye. Symptoms include eye pain and redness, blurred vision, seeing floaters, light sensitivity, decreased vision, and a whitish area on the inside of the lower part of the iris.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveitis" returned 895 free, full-text research articles on human participants. First 3 results:

Adalimumab in Patients with Active Noninfectious Uveitis.
 

Author(s): Glenn J Jaffe, Andrew D Dick, Antoine P Brézin, Quan Dong Nguyen, Jennifer E Thorne, Philippe Kestelyn, Talin Barisani-Asenbauer, Pablo Franco, Arnd Heiligenhaus, David Scales, David S Chu, Anne Camez, Nisha V Kwatra, Alexandra P Song, Martina Kron, Samir Tari, Eric B Suhler

Journal: N. Engl. J. Med.. 2016 Sep;375(10):932-43.

 

Background Patients with noninfectious uveitis are at risk for long-term complications of uncontrolled inflammation, as well as for the adverse effects of long-term glucocorticoid therapy. We conducted a trial to assess the efficacy and safety of adalimumab as a glucocorticoid-sparing ...

Last Updated: 8 Sep 2016

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Uveitis Associated with Zika Virus Infection.
 

Author(s): João M Furtado, Danillo L Espósito, Taline M Klein, Tomás Teixeira-Pinto, Benedito A da Fonseca

Journal: N. Engl. J. Med.. 2016 Jul;375(4):394-6.

 

Last Updated: 28 Jul 2016

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Vision-Related Quality of Life in Patients with Inactive HLA-B27-Associated-Spectrum Anterior Uveitis.
 

Author(s): Lisette Hoeksema, Leonoor I Los

Journal:

 

We investigated the vision-related quality of life (VR-QOL) in patients with HLA-B27 associated anterior uveitis (AU). The study was conducted in 2012 at the ophthalmology department of the University Medical Center of Groningen. We included AU patients who were HLA-B27 positive and/or ...

Last Updated: 26 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveitis" returned 105 free, full-text review articles on human participants. First 3 results:

Uveitis in juvenile idiopathic arthritis: recent therapeutic advances.
 

Author(s): Jane M Wells, Justine R Smith

Journal: Ophthalmic Res.. 2015 ;54(3):124-7.

 

Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients with this condition, ...

Last Updated: 7 Oct 2015

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New Immunosuppressive Therapies in Uveitis Treatment.
 

Author(s): Salvador Mérida, Elena Palacios, Amparo Navea, Francisco Bosch-Morell

Journal:

 

Uveitis is an inflammatory process that initially starts in the uvea, but can also affect other adjacent eye structures, and is currently the fourth cause of blindness in developed countries. Corticoids are probably the most widespread treatment, but resorting to other immunosuppressive ...

Last Updated: 14 Aug 2015

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Successful Treatment with Infliximab for Refractory Uveitis in a Hemodialysis Patient with Behçet's Disease and a Review of the Literature for Infliximab Use in Patients on Hemodialysis.
 

Author(s): Izumi Kurata, Hiroto Tsuboi, Hidenori Takahashi, Saori Abe, Hiroshi Ebe, Shinya Hagiwara, Naoto Umeda, Yuya Kondo, Hiroshi Ogishima, Takeshi Suzuki, Isao Matsumoto, Sujin Hoshi, Tetsuro Oshika, Takayuki Sumida

Journal: Intern. Med.. 2015 ;54(12):1553-7.

 

A 36-year-old man with a 16-year history of refractory Behçet's disease (BD)-associated uveitis and chronic renal failure requiring hemodialysis suffered from frequent ocular attacks despite treatment with systemic corticosteroids and cyclosporine A. Following infliximab administration, ...

Last Updated: 15 Jun 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis
 

Status: Recruiting

Condition Summary: Uveitis; Uveitis, Posterior; Uveitis, Anterior; Uveitis, Intermediate; Panuveitis

 

Last Updated: 14 Jul 2016

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Sirolimus as Therapeutic Approach to Uveitis
 

Status: Recruiting

Condition Summary: Uveitis; Intermediate Uveitis; Posterior Uveitis; Panuveitis

 

Last Updated: 25 May 2010

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Intravitreal Sirolimus as Therapeutic Approach to Uveitis
 

Status: Recruiting

Condition Summary: Uveitis; Intermediate Uveitis; Posterior Uveitis; Panuveitis

 

Last Updated: 18 Aug 2016

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