Uveitis

Common Name(s)

Uveitis

Uveitis is inflammation of the middle layer of the eye called the uvea. The uvea consists of the layer and structures beneath the white of the eye. The uvea is made up of the iris, the choroid layer, and the ciliary body. The iris is the colored part of the eye, the choroid layer is the layer of blood vessels and connective tissue, and the ciliary body is the structure in the eye that releases the transparent liquid in the eye. The cause of uveitis is unknown but may be associated with infections, injury, inflammatory and autoimmune disorders, and certain cancers that can affect the eye. Symptoms include eye pain and redness, blurred vision, seeing floaters, light sensitivity, decreased vision, and a whitish area on the inside of the lower part of the iris.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveitis" returned 745 free, full-text research articles on human participants. First 3 results:

[Woman with recurrent uveitis and neurological symptoms].
 

Author(s): Monika Mochol, Karina Berg, Øyvind Midtvedt, Geir Ringstad, Emilia Kerty

Journal:

 

Last Updated: 3 Jul 2014

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[Behcet's refractory uveitis treated successfully by infliximab].
 

Author(s): Madiha Mahfoudhi, Anis Hariz, Khaoula Ben Abdelghani, Sami Turki, Adel Kheder

Journal: Tunis Med. 2014 Jan;92(1):41-2.

 

Last Updated: 2 Jun 2014

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Usefulness of adalimumab in the treatment of refractory uveitis associated with juvenile idiopathic arthritis.
 

Author(s): Carmen García-De-Vicuña, Manuel Díaz-Llopis, David Salom, Rosa Bou, Jesus Díaz-Cascajosa, Miguel Cordero-Coma, Gabriela Ortega, Norberto Ortego-Centeno, Marta Suarez-De-Figueroa, Juan Cruz-Martínez, Alex Fonollosa, Ricardo Blanco, Ángel María García-Aparicio, Jose M Benítez-Del-Castillo, Jordi Antón

Journal: Mediators Inflamm.. 2013 ;2013():560632.

 

To assess the efficacy and safety of adalimumab in patients with juvenile idiopathic arthritis (JIA) and associated refractory uveitis.

Last Updated: 3 Feb 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveitis" returned 79 free, full-text review articles on human participants. First 3 results:

Cytokines and Biologics in non-infectious autoimmune uveitis: bench to bedside.
 

Author(s): Rupesh Agrawal, Jayant Iyer, John Connolly, Daiju Iwata, Stephen Teoh

Journal: Indian J Ophthalmol. 2014 Jan;62(1):74-81.

 

Intraocular inflammatory eye disease is one of the important causes of ocular morbidity. Even though the prevalence of uveitis is less common in relation to diabetic retinopathy, glaucoma or age related macular degeneration, the complexity and heterogeneity of the disease makes it ...

Last Updated: 4 Feb 2014

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The future of uveitis treatment.
 

Author(s): Phoebe Lin, Eric B Suhler, James T Rosenbaum

Journal: Ophthalmology. 2014 Jan;121(1):365-76.

 

Uveitis is a heterogeneous collection of diseases with polygenic and environmental influences. This heterogeneity presents challenges in trial design and selection of end points. Despite the multitude of causes, therapeutics targeting common inflammatory pathways are effective in ...

Last Updated: 6 Jan 2014

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Off-label uses of anti-TNF therapy in three frequent disorders: Behçet's disease, sarcoidosis, and noninfectious uveitis.
 

Author(s): Daniel Sánchez-Cano, José Luis Callejas-Rubio, Ricardo Ruiz-Villaverde, Raquel Ríos-Fernández, Norberto Ortego-Centeno

Journal: Mediators Inflamm.. 2013 ;2013():286857.

 

Tumoral necrosis factor α plays a central role in both the inflammatory response and that of the immune system. Thus, its blockade with the so-called anti-TNF agents (infliximab, etanercept, adalimumab, certolizumab pegol, and golimumab) has turned into the most important tool in ...

Last Updated: 28 Aug 2013

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sirolimus as Therapeutic Approach to Uveitis
 

Status: Recruiting

Condition Summary: Uveitis; Intermediate Uveitis; Posterior Uveitis; Panuveitis

 

Last Updated: 25 May 2010

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Intravitreal Sirolimus as Therapeutic Approach to Uveitis
 

Status: Not yet recruiting

Condition Summary: Uveitis; Intermediate Uveitis; Posterior Uveitis; Panuveitis

 

Last Updated: 20 Jan 2011

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Safety &Efficacy of CF101 to Subjects With Uveitis
 

Status: Not yet recruiting

Condition Summary: Uveitis, Posterior; Uveitis, Intermediate

 

Last Updated: 30 Jul 2014

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