Uveitis

Common Name(s)

Uveitis

Uveitis is inflammation of the middle layer of the eye called the uvea. The uvea consists of the layer and structures beneath the white of the eye. The uvea is made up of the iris, the choroid layer, and the ciliary body. The iris is the colored part of the eye, the choroid layer is the layer of blood vessels and connective tissue, and the ciliary body is the structure in the eye that releases the transparent liquid in the eye. The cause of uveitis is unknown but may be associated with infections, injury, inflammatory and autoimmune disorders, and certain cancers that can affect the eye. Symptoms include eye pain and redness, blurred vision, seeing floaters, light sensitivity, decreased vision, and a whitish area on the inside of the lower part of the iris.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Uveitis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Uveitis" returned 905 free, full-text research articles on human participants. First 3 results:

Adalimumab in Patients with Active Noninfectious Uveitis.
 

Author(s): Glenn J Jaffe, Andrew D Dick, Antoine P Brézin, Quan Dong Nguyen, Jennifer E Thorne, Philippe Kestelyn, Talin Barisani-Asenbauer, Pablo Franco, Arnd Heiligenhaus, David Scales, David S Chu, Anne Camez, Nisha V Kwatra, Alexandra P Song, Martina Kron, Samir Tari, Eric B Suhler

Journal: N. Engl. J. Med.. 2016 Sep;375(10):932-43.

 

Patients with noninfectious uveitis are at risk for long-term complications of uncontrolled inflammation, as well as for the adverse effects of long-term glucocorticoid therapy. We conducted a trial to assess the efficacy and safety of adalimumab as a glucocorticoid-sparing agent ...

Last Updated: 8 Sep 2016

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Uveitis Associated with Zika Virus Infection.
 

Author(s): João M Furtado, Danillo L Espósito, Taline M Klein, Tomás Teixeira-Pinto, Benedito A da Fonseca

Journal: N. Engl. J. Med.. 2016 Jul;375(4):394-6.

 

Last Updated: 28 Jul 2016

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Elevated CD1c+ Myeloid Dendritic Cell Proportions Associate With Clinical Activity and Predict Disease Reactivation in Noninfectious Uveitis.
 

Author(s): Ping Chen, Cristhian A Urzua, Jared E Knickelbein, Jane S Kim, Zhiyu Li, Susan Hannes, David Kuo, Benjamin Chaigne-Delalande, Karen Armbrust, William Tucker, Baoying Liu, Elvira Agrón, H Nida Sen, Robert B Nussenblatt

Journal: Invest. Ophthalmol. Vis. Sci.. 2016 Apr;57(4):1765-72.

 

To test the association between elevated proportions of CD1c+ myeloid dendritic cells (mDCs) and disease activation/reactivation in noninfectious uveitis.

Last Updated: 13 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Uveitis" returned 106 free, full-text review articles on human participants. First 3 results:

Acute bilateral uveitis and right macular edema induced by a single infusion of zoledronic acid for the treatment of postmenopausal osteoporosis as a substitution for oral alendronate: a case report.
 

Author(s): Yiming Tian, Rui Wang, Lianyuan Liu, Chunming Ma, Qiang Lu, Fuzai Yin

Journal:

 

Zoledronic acid-induced uveitis (ZAIU) is rare but severe, and has been recently considered part of an acute phase reaction. Only 15 cases have been reported since 2005. Here we describe a case with macular edema, which is the first reported case observed after long-term alendronate tolerance.

Last Updated: 12 Feb 2016

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Uveitis in juvenile idiopathic arthritis: recent therapeutic advances.
 

Author(s): Jane M Wells, Justine R Smith

Journal: Ophthalmic Res.. 2015 ;54(3):124-7.

 

Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment. Since corticosteroid treatment is not a preferred long-term option for most patients with this condition, ...

Last Updated: 7 Oct 2015

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New Immunosuppressive Therapies in Uveitis Treatment.
 

Author(s): Salvador Mérida, Elena Palacios, Amparo Navea, Francisco Bosch-Morell

Journal:

 

Uveitis is an inflammatory process that initially starts in the uvea, but can also affect other adjacent eye structures, and is currently the fourth cause of blindness in developed countries. Corticoids are probably the most widespread treatment, but resorting to other immunosuppressive ...

Last Updated: 14 Aug 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Ustekinumab (STELARA ) for the Treatment of Active Sight-Threatening Uveitis
 

Status: Recruiting

Condition Summary: Uveitis

 

Last Updated: 16 Nov 2016

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Grading Scale of Vitreous Haze in Patients With Uveitis Using Ultrasonography
 

Status: Not yet recruiting

Condition Summary: Uveitis

 

Last Updated: 30 Nov 2015

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Open Label Study of Acthar SQ Gel Injection in Patients With Active Anterior Uveitis
 

Status: Not yet recruiting

Condition Summary: Uveitis

 

Last Updated: 10 May 2016

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