Hypoglycemia

Common Name(s)

Hypoglycemia, Low blood sugar

Hypoglycemia, also known as low blood sugar, is an abnormally low level of glucose (sugar) in the blood. Since glucose is the body’s main source of energy, long periods of low blood sugar can cause significant health problems, including seizures, loss of consciousness, or even death. Initial signs of hypoglycemia include an abnormal heartbeat (palpitations), low energy (fatigue), anxiety, irritability, trembling, and weakness. Without treatment, hypoglycemia can lead to poor concentration, numbness of the mouth, blurred vision and coma.

Hypoglycemia is considered a symptom and not a disease. There are many causes of hypoglycemia. The most common reason is a reaction to certain diabetes medications, specifically insulin. Other less common causes of hypoglycemia include excessive alcohol consumption, certain liver diseases, conditions that cause a person to make too much insulin, and genetic conditions that stop a person from breaking down certain parts of food (protein, fats and sugars). If you or your child’s doctor suspects hypoglycemia, they can confirm the diagnosis by measuring a blood glucose level. A person meets the criteria for hypoglycemia if their symptoms are present during times of low blood sugar and they go away when the blood sugar returns to normal. The treatment of hypoglycemia depends on the cause. The goal of treatment is to raise blood sugar, which can usually be done by consuming fast-acting sugars like candy and fruit juice. If the hypoglycemia is severe enough, your doctor may use glucagon, a hormone that tells your body to immediately raise the blood sugar. If you or your child has been diagnosed with hypoglycemia, talk with your doctor to identify the cause and determine the best treatment.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoglycemia" returned 858 free, full-text research articles on human participants. First 3 results:

Non-islet cell tumor hypoglycemia caused by intrathoracic solitary fibrous tumor: a case report.
 

Author(s): Masahiro Kitada, Shunsuke Yasuda, Nana Takahashi, Satoshi Okazaki, Kei Ishibashi, Satoshi Hayashi, Yoshinobu Ohsaki, Naoyuki Miyokawa

Journal:

 

Non-islet cell tumor hypoglycemia (NICTH) is defined as a form of hypoglycemia caused by an extrapancreatic tumor. Solitary fibrous tumor (SFT) associated with hypoglycemia is rare.

Last Updated: 11 Apr 2016

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Economic Burden of Hypoglycemia in Patients with Type 2 Diabetes Mellitus from Korea.
 

Author(s): Gyuri Kim, Yong-Ho Lee, Mi Hye Han, Eui-Kyung Lee, Chong Hwa Kim, Hyuk Sang Kwon, In Kyung Jeong, Eun Seok Kang, Dae Jung Kim

Journal:

 

Hypoglycemia is a very serious complication in patients with type 2 diabetes mellitus (T2DM) and affects the economic burden of treatment. This study aims to create models of the cost of treating hypoglycemia in patients with T2DM based upon physician estimates of medical resource usage.

Last Updated: 15 Mar 2016

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Hypoglycemia and Medical Expenses in Patients with Type 2 Diabetes Mellitus: An Analysis Based on the Korea National Diabetes Program Cohort.
 

Author(s): Sang Youl Rhee, Soo Min Hong, Suk Chon, Kyu Jeung Ahn, Sung Hoon Kim, Sei Hyun Baik, Yong Soo Park, Moon Suk Nam, Kwan Woo Lee, Jeong-Taek Woo, Young Seol Kim

Journal:

 

Hypoglycemia is one of the most important adverse events in individuals with type 2 diabetes mellitus (T2DM). However, hypoglycemia-related events are usually overlooked and have been documented less in clinical practice.

Last Updated: 19 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoglycemia" returned 82 free, full-text review articles on human participants. First 3 results:

Hyperinsulinemic Hypoglycemia in Infancy: Current Concepts in Diagnosis and Management.
 

Author(s): Shrenik Vora, Suresh Chandran, Victor Samuel Rajadurai, Khalid Hussain

Journal: Indian Pediatr. 2015 Dec;52(12):1051-9.

 

Molecular basis of various forms of hyperinsulinemic hypoglycemia, involving defects in key genes regulating insulin secretion, are being increasingly reported. However, the management of medically unresponsive hyperinsulinism still remains a challenge as current facilities for genetic ...

Last Updated: 30 Dec 2015

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Brain glucose metabolism during hypoglycemia in type 1 diabetes: insights from functional and metabolic neuroimaging studies.
 

Author(s): Hanne M M Rooijackers, Evita C Wiegers, Cees J Tack, Marinette van der Graaf, Bastiaan E de Galan

Journal: Cell. Mol. Life Sci.. 2016 Feb;73(4):705-22.

 

Hypoglycemia is the most frequent complication of insulin therapy in patients with type 1 diabetes. Since the brain is reliant on circulating glucose as its main source of energy, hypoglycemia poses a threat for normal brain function. Paradoxically, although hypoglycemia commonly ...

Last Updated: 2 Feb 2016

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Vascular Glucose Sensor Symposium: Continuous Glucose Monitoring Systems (CGMS) for Hospitalized and Ambulatory Patients at Risk for Hyperglycemia, Hypoglycemia, and Glycemic Variability.
 

Author(s): Jeffrey I Joseph, Marc C Torjman, Paul J Strasma

Journal: J Diabetes Sci Technol. 2015 Jul;9(4):725-38.

 

Hyperglycemia, hypoglycemia, and glycemic variability have been associated with increased morbidity, mortality, length of stay, and cost in a variety of critical care and non-critical care patient populations in the hospital. The results from prospective randomized clinical trials ...

Last Updated: 1 Jul 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prophylactic Dextrose Gel for Newborns at High-risk for Hypoglycemia
 

Status: Recruiting

Condition Summary: Hypoglycemia; Infant, Small for Gestational Age; Premature Birth of Newborn; Fetal Macrosomia; Intrauterine Growth Restriction; Complication of Prematurity; Neonatal Hypoglycemia

 

Last Updated: 1 Aug 2016

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Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia
 

Status: Recruiting

Condition Summary: Type 1 Diabetes Mellitus; Nocturnal Hypoglycemia; Recurrent Severe Hypoglycaemia

 

Last Updated: 27 Apr 2016

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Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia
 

Status: Available

Condition Summary: Hyperinsulinemic Hypoglycemia, Persistent; Congenital Hyperinsulinism; Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)

 

Last Updated: 25 Aug 2015

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