Hypoglycemia

Common Name(s)

Hypoglycemia, Low blood sugar

Hypoglycemia, also known as low blood sugar, is an abnormally low level of glucose (sugar) in the blood. Since glucose is the body’s main source of energy, long periods of low blood sugar can cause significant health problems, including seizures, loss of consciousness, or even death. Initial signs of hypoglycemia include an abnormal heartbeat (palpitations), low energy (fatigue), anxiety, irritability, trembling, and weakness. Without treatment, hypoglycemia can lead to poor concentration, numbness of the mouth, blurred vision and coma.

Hypoglycemia is considered a symptom and not a disease. There are many causes of hypoglycemia. The most common reason is a reaction to certain diabetes medications, specifically insulin. Other less common causes of hypoglycemia include excessive alcohol consumption, certain liver diseases, conditions that cause a person to make too much insulin, and genetic conditions that stop a person from breaking down certain parts of food (protein, fats and sugars). If you or your child’s doctor suspects hypoglycemia, they can confirm the diagnosis by measuring a blood glucose level. A person meets the criteria for hypoglycemia if their symptoms are present during times of low blood sugar and they go away when the blood sugar returns to normal. The treatment of hypoglycemia depends on the cause. The goal of treatment is to raise blood sugar, which can usually be done by consuming fast-acting sugars like candy and fruit juice. If the hypoglycemia is severe enough, your doctor may use glucagon, a hormone that tells your body to immediately raise the blood sugar. If you or your child has been diagnosed with hypoglycemia, talk with your doctor to identify the cause and determine the best treatment.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoglycemia" returned 790 free, full-text research articles on human participants. First 3 results:

Severe Hypoglycemia Caused by Recurrent Sarcomatoid Carcinoma in the Pelvic Cavity: A Case Report.
 

Author(s): Chao Fang, Chuan Wen Fan, Yong Yang Yu, Cun Wang, Lie Yang, Yuan Li, Xian Ming Mo, Zong Guang Zhou

Journal: Medicine (Baltimore). 2015 Oct;94(42):e1577.

 

Nonislet cell tumor hypoglycemia (NICTH) is a paraneoplastic syndrome characterized by persistent, severe hypoglycemia in different tumor types of mesochymal or epithelial origin; however, NICTH is infrequently induced by sarcomatoid carcinoma (SC). Despite some sarcomatoid and epithelioid ...

Last Updated: 27 Oct 2015

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Neonatal Hypoglycemia Studies--Is There a Sweet Story of Success Yet?
 

Author(s): Rebecca Simmons, Charles Stanley

Journal: N. Engl. J. Med.. 2015 Oct;373(16):1567-9.

 

Last Updated: 15 Oct 2015

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Effectiveness of Prior Use of Beta-Blockers for Preventing Adverse Influences of Severe Hypoglycemia in Patients With Diabetes: An Observational Study.
 

Author(s): Tetsuro Tsujimoto, Ritsuko Yamamoto-Honda, Hiroshi Kajio, Miyako Kishimoto, Hiroshi Noto, Remi Hachiya, Akio Kimura, Masafumi Kakei, Mitsuhiko Noda

Journal: Medicine (Baltimore). 2015 Sep;94(39):e1629.

 

The study aimed to identify predictors of severe acute hypertension (≥ 180/110 mmHg) during severe hypoglycemia and to assess the efficacy of prior use of catecholamine-blocking agents for preventing adverse influences in diabetic patients with severe hypoglycemia. We performed ...

Last Updated: 2 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoglycemia" returned 76 free, full-text review articles on human participants. First 3 results:

Avoiding or coping with severe hypoglycemia in patients with type 2 diabetes.
 

Author(s): Jae-Seung Yun, Seung-Hyun Ko

Journal: Korean J. Intern. Med.. 2015 Jan;30(1):6-16.

 

Hypoglycemia is a major barrier to achieving the glycemic goal in patients with type 2 diabetes. In particular, severe hypoglycemia, which is defined as an event that requires the assistance of another person to actively administer carbohydrates, glucagon, or take other corrective ...

Last Updated: 15 Jan 2015

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Intranasal glucagon: a promising approach for treatment of severe hypoglycemia.
 

Author(s): Antonio E Pontiroli

Journal: J Diabetes Sci Technol. 2015 Jan;9(1):38-43.

 

Prevention of diabetic complications is mainly obtained through optimal control of blood glucose levels. With hypoglycemic drugs like beta-cell stimulating drugs and especially insulin, the limit to treatment is represented by hypoglycemia, a life-threatening occurrence that is dangerous ...

Last Updated: 31 Dec 2014

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Minimizing morbidity of hypoglycemia in diabetes: a review of mini-dose glucagon.
 

Author(s): Stephanie T Chung, Morey W Haymond

Journal: J Diabetes Sci Technol. 2015 Jan;9(1):44-51.

 

Type 1 diabetes is a common chronic disease of childhood and one of the most difficult conditions to manage. Advances in insulin formulations and insulin delivery devices have markedly improved the ability to achieve normal glucose homeostasis. However, hypoglycemia remains the primary ...

Last Updated: 31 Dec 2014

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia
 

Status: Recruiting

Condition Summary: Type 1 Diabetes Mellitus; Nocturnal Hypoglycemia; Recurrent Severe Hypoglycaemia

 

Last Updated: 7 Oct 2015

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Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia
 

Status: Available

Condition Summary: Hyperinsulinemic Hypoglycemia, Persistent; Congenital Hyperinsulinism; Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)

 

Last Updated: 25 Aug 2015

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Hypoglycemia and Autonomic Nervous System Function
 

Status: Recruiting

Condition Summary: Hypoglycemia

 

Last Updated: 20 Mar 2013

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