Hypoglycemia

Common Name(s)

Hypoglycemia, Low blood sugar

Hypoglycemia, also known as low blood sugar, is an abnormally low level of glucose (sugar) in the blood. Since glucose is the body’s main source of energy, long periods of low blood sugar can cause significant health problems, including seizures, loss of consciousness, or even death. Initial signs of hypoglycemia include an abnormal heartbeat (palpitations), low energy (fatigue), anxiety, irritability, trembling, and weakness. Without treatment, hypoglycemia can lead to poor concentration, numbness of the mouth, blurred vision and coma.

Hypoglycemia is considered a symptom and not a disease. There are many causes of hypoglycemia. The most common reason is a reaction to certain diabetes medications, specifically insulin. Other less common causes of hypoglycemia include excessive alcohol consumption, certain liver diseases, conditions that cause a person to make too much insulin, and genetic conditions that stop a person from breaking down certain parts of food (protein, fats and sugars). If you or your child’s doctor suspects hypoglycemia, they can confirm the diagnosis by measuring a blood glucose level. A person meets the criteria for hypoglycemia if their symptoms are present during times of low blood sugar and they go away when the blood sugar returns to normal. The treatment of hypoglycemia depends on the cause. The goal of treatment is to raise blood sugar, which can usually be done by consuming fast-acting sugars like candy and fruit juice. If the hypoglycemia is severe enough, your doctor may use glucagon, a hormone that tells your body to immediately raise the blood sugar. If you or your child has been diagnosed with hypoglycemia, talk with your doctor to identify the cause and determine the best treatment.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoglycemia" returned 968 free, full-text research articles on human participants. First 3 results:

Executive function assessment in New Zealand 2-year olds born at risk of neonatal hypoglycemia.
 

Author(s): Judith M Ansell, Trecia A Wouldes, Jane E Harding,

Journal:

 

A growing number of babies are born with perinatal risk factors that may impair later development. These children are often assessed at 2 years to help predict outcome and direct support services. Executive function is an important predictor of academic achievement and behavior, but ...

Last Updated: 31 Dec 1969

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Poly((D,L)lactic-glycolic)acid-star glucose nanoparticles for glucose transporter and hypoglycemia-mediated tumor targeting.
 

Author(s): Ju-Hwan Park, Hyun-Jong Cho, Dae-Duk Kim

Journal:

 

Poly((D,L)lactic-glycolic)acid-star glucose (PLGA-Glc) polymer-based nanoparticles (NPs) were fabricated for tumor-targeted delivery of docetaxel (DCT). NPs with an approximate mean diameter of 241 nm, narrow size distribution, negative zeta potential, and spherical shape were prepared. ...

Last Updated: 31 Dec 1969

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Association of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes.
 

Author(s): Beate Karges, Anke Schwandt, Bettina Heidtmann, Olga Kordonouri, Elisabeth Binder, Ulrike Schierloh, Claudia Boettcher, Thomas Kapellen, Joachim Rosenbauer, Reinhard W Holl

Journal: JAMA. 2017 10;318(14):1358-1366.

 

Insulin pump therapy may improve metabolic control in young patients with type 1 diabetes, but the association with short-term diabetes complications is unclear.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoglycemia" returned 89 free, full-text review articles on human participants. First 3 results:

Metrics Beyond Hemoglobin A1C in Diabetes Management: Time in Range, Hypoglycemia, and Other Parameters.
 

Author(s): Lorena Alarcon-Casas Wright, Irl B Hirsch

Journal: Diabetes Technol. Ther.. 2017 May;19(S2):S16-S26.

 

We review clinical instances in which A1C should not be used and reflect on the use of other glucose metrics that can be used, in substitution of or in combination with A1C and SMBG, to tailor an individualized approach that will result in better outcomes and patient empowerment.

Last Updated: 31 Dec 1969

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MANAGEMENT OF ENDOCRINE DISEASE: Pathogenesis and management of hypoglycemia.
 

Author(s): Nana Esi Kittah, Adrian Vella

Journal: Eur. J. Endocrinol.. 2017 Jul;177(1):R37-R47.

 

Glucose is the main substrate utilized by the brain and as such multiple regulatory mechanisms exist to maintain glucose concentrations. When these mechanisms fail or are defective, hypoglycemia ensues. Due to these robust mechanisms, hypoglycemia is uncommon and usually occurs in ...

Last Updated: 31 Dec 1969

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Sensor-Augmented Insulin Pumps and Hypoglycemia Prevention in Type 1 Diabetes.
 

Author(s): Isabelle Steineck, Ajenthen Ranjan, Kirsten Nørgaard, Signe Schmidt

Journal: J Diabetes Sci Technol. 2017 01;11(1):50-58.

 

Hypoglycemia can lead to seizures, unconsciousness, or death. Insulin pump treatment reduces the frequency of severe hypoglycemia compared with multiple daily injections treatment. The addition of a continuous glucose monitor, so-called sensor-augmented pump (SAP) treatment, has the ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Hypoglycemia and the Gut Microbiome
 

Status: Not yet recruiting

Condition Summary: Hypoglycemia

 

Last Updated: 15 Feb 2018

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Last Updated: 2 Feb 2017

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Continuous Glucose Monitoring to Reduce Hypoglycemia and Improve Safety in Patients With Hypoglycemia After Gastric Surgery
 

Status: Not yet recruiting

Condition Summary: Hypoglycemia, Reactive; Hypoglycemia

 

Last Updated: 15 Feb 2018

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