Hypoglycemia

Common Name(s)

Hypoglycemia, Low blood sugar

Hypoglycemia, also known as low blood sugar, is an abnormally low level of glucose (sugar) in the blood. Since glucose is the body’s main source of energy, long periods of low blood sugar can cause significant health problems, including seizures, loss of consciousness, or even death. Initial signs of hypoglycemia include an abnormal heartbeat (palpitations), low energy (fatigue), anxiety, irritability, trembling, and weakness. Without treatment, hypoglycemia can lead to poor concentration, numbness of the mouth, blurred vision and coma.

Hypoglycemia is considered a symptom and not a disease. There are many causes of hypoglycemia. The most common reason is a reaction to certain diabetes medications, specifically insulin. Other less common causes of hypoglycemia include excessive alcohol consumption, certain liver diseases, conditions that cause a person to make too much insulin, and genetic conditions that stop a person from breaking down certain parts of food (protein, fats and sugars). If you or your child’s doctor suspects hypoglycemia, they can confirm the diagnosis by measuring a blood glucose level. A person meets the criteria for hypoglycemia if their symptoms are present during times of low blood sugar and they go away when the blood sugar returns to normal. The treatment of hypoglycemia depends on the cause. The goal of treatment is to raise blood sugar, which can usually be done by consuming fast-acting sugars like candy and fruit juice. If the hypoglycemia is severe enough, your doctor may use glucagon, a hormone that tells your body to immediately raise the blood sugar. If you or your child has been diagnosed with hypoglycemia, talk with your doctor to identify the cause and determine the best treatment.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

Last Updated: 2 Aug 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Hypoglycemia" for support, advocacy or research.

Isabella's Aviary Alliance, LLC

Isabella’s Aviary Alliance, LLC actively demonstrates, through Isabella’s passionate and loving care in breeding and raising baby parrots for other special needs children, the possibility for two hearts—bird and child—coming together and connecting in a way which infinitely brightens the lives of both.

http://www.isabellasaviary.com

Last Updated: 2 Aug 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Hypoglycemia" returned 843 free, full-text research articles on human participants. First 3 results:

Non-Islet Cell Tumor Hypoglycemia Is Caused by Big IGF-II in a Patient with a Carcinosarcoma of the Uterus.
 

Author(s): Hiroyuki Honma, Yoshihiko Takahashi, Mizue Matsui, Takashi Satoh, Izumi Fukuda, Kazuma Takahashi, Noriko Takebe, Kan Nagasawa, Mitsutaka Ono, Takayoshi Sasai, Takashi Kajiwara, Tamotsu Sugai, Jo Satoh, Yasushi Ishigaki

Journal: Intern. Med.. 2015 ;54(24):3165-9.

 

We report a 72-year-old Japanese woman with severe hypoglycemia. The laboratory data, which revealed the suppression of serum insulin, suggested the existence of non-islet cell tumor hypoglycemia (NICTH). Abdominal computed tomography demonstrated the presence of a huge uterine tumor. ...

Last Updated: 15 Dec 2015

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Hypoglycemia revealing arachnoidocele in infant.
 

Author(s): Manel Jellouli, Tahar Gargah

Journal:

 

Last Updated: 15 Dec 2015

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Can Fasting Glucose Levels or Post-Breakfast Glucose Fluctuations Predict the Occurrence of Nocturnal Asymptomatic Hypoglycemia in Type 1 Diabetic Patients Receiving Basal-Bolus Insulin Therapy with Long-Acting Insulin?
 

Author(s): Sumie Mitsuishi, Rimei Nishimura, Kiyotaka Ando, Daisuke Tsujino, Kazunori Utsunomiya

Journal:

 

To investigate whether the occurrence of nocturnal asymptomatic hypoglycemia may be predicted based on fasting glucose levels and post-breakfast glucose fluctuations.

Last Updated: 2 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Hypoglycemia" returned 81 free, full-text review articles on human participants. First 3 results:

Brain glucose metabolism during hypoglycemia in type 1 diabetes: insights from functional and metabolic neuroimaging studies.
 

Author(s): Hanne M M Rooijackers, Evita C Wiegers, Cees J Tack, Marinette van der Graaf, Bastiaan E de Galan

Journal: Cell. Mol. Life Sci.. 2016 Feb;73(4):705-22.

 

Hypoglycemia is the most frequent complication of insulin therapy in patients with type 1 diabetes. Since the brain is reliant on circulating glucose as its main source of energy, hypoglycemia poses a threat for normal brain function. Paradoxically, although hypoglycemia commonly ...

Last Updated: 2 Feb 2016

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Vascular Glucose Sensor Symposium: Continuous Glucose Monitoring Systems (CGMS) for Hospitalized and Ambulatory Patients at Risk for Hyperglycemia, Hypoglycemia, and Glycemic Variability.
 

Author(s): Jeffrey I Joseph, Marc C Torjman, Paul J Strasma

Journal: J Diabetes Sci Technol. 2015 Jul;9(4):725-38.

 

Hyperglycemia, hypoglycemia, and glycemic variability have been associated with increased morbidity, mortality, length of stay, and cost in a variety of critical care and non-critical care patient populations in the hospital. The results from prospective randomized clinical trials ...

Last Updated: 1 Jul 2015

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Evidence-informed clinical practice recommendations for treatment of type 1 diabetes complicated by problematic hypoglycemia.
 

Author(s): Pratik Choudhary, Michael R Rickels, Peter A Senior, Marie-Christine Vantyghem, Paola Maffi, Thomas W Kay, Bart Keymeulen, Nobuya Inagaki, Frantisek Saudek, Roger Lehmann, Bernhard J Hering

Journal: Diabetes Care. 2015 Jun;38(6):1016-29.

 

Problematic hypoglycemia, defined as two or more episodes per year of severe hypoglycemia or as one episode associated with impaired awareness of hypoglycemia, extreme glycemic lability, or major fear and maladaptive behavior, is a challenge, especially for patients with long-standing ...

Last Updated: 22 May 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prophylactic Dextrose Gel for Newborns at High-risk for Hypoglycemia
 

Status: Recruiting

Condition Summary: Hypoglycemia; Infant, Small for Gestational Age; Premature Birth of Newborn; Fetal Macrosomia; Intrauterine Growth Restriction; Complication of Prematurity; Neonatal Hypoglycemia

 

Last Updated: 6 Jul 2016

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Insulin Degludec and Symptomatic Nocturnal Hypoglycaemia
 

Status: Recruiting

Condition Summary: Type 1 Diabetes Mellitus; Nocturnal Hypoglycemia; Recurrent Severe Hypoglycaemia

 

Last Updated: 27 Apr 2016

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Study of the Use of [18F]-DOPA in Hyperinsulinemic Hypoglycemia
 

Status: Available

Condition Summary: Hyperinsulinemic Hypoglycemia, Persistent; Congenital Hyperinsulinism; Persistent Hyperinsulinemic Hypoglycemia of Infancy (PHHI)

 

Last Updated: 25 Aug 2015

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