Lyme disease

Common Name(s)

Lyme disease

Lyme disease is an infection caused by three types of Borrellia bacteria. One type is most common in the United States, while the other two types are more common in Europe and Asia. These bacteria are carried by certain ticks; in the United States most commonly the deer tick, in Europe the sheep tick, and in China the taiga tick. An infected tick can pass the bacteria to humans (and other animals) through its bites. However, the transfer of bacteria is believed to only begin after 36-48 hours of the tick being attached.

A characteristic circular rash often develops around the tick bite within 3-30 days and is diagnostic, meaning treatment should begin immediately. Sometimes the rash appears like a bull’s-eye, other times it is a solid red patch, and sometimes the rash does not occur exactly at the site of the tick bite. Other early symptoms include flu like symptoms such as fever, chills, and body aches. Laboratory blood tests are not considered reliable until at least one month after becoming infected through a tick bite. Therefore, it is important if you have flu like symptoms with or without a rash to let your doctor know you have been bitten by a tick within a month’s time.

As symptoms progress, an individual may have a stiff neck, severe fatigue, tingling sensation in the hands or feet, or facial paralysis. Left untreated, later symptoms may involve the joints, heart, and central nervous system. In most cases, the infection and its symptoms are eliminated by antibiotics, especially if the illness is treated early. Delayed or inadequate treatment can lead to more serious symptoms, which can be disabling and difficult to treat. If you or a family member has been diagnosed with Lyme disease, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme disease" for support, advocacy or research.

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American Lyme Disease Foundation

The American Lyme Disease Foundation, Inc. is dedicated to the prevention, diagnosis and treatment of Lyme disease. The Foundation plays a key role in providing reliable and scientifically accurate information to the public, medical community and government agencies about Lyme disease and its effects on human health and quality of life.

Last Updated: 7 Jan 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme disease" for support, advocacy or research.

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American Lyme Disease Foundation

The American Lyme Disease Foundation, Inc. is dedicated to the prevention, diagnosis and treatment of Lyme disease. The Foundation plays a key role in providing reliable and scientifically accurate information to the public, medical community and government agencies about Lyme disease and its effects on human health and quality of life.

http://www.aldf.com

Last Updated: 7 Jan 2015

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lyme disease" returned 648 free, full-text research articles on human participants. First 3 results:

Transplantation of Human Embryonic Stem Cells in Patients with Multiple Sclerosis and Lyme Disease.
 

Author(s): Geeta Shroff

Journal:

 

BACKGROUND Multiple sclerosis (MS) is an inflammatory and neurodegenerative disease in which the myelin sheath of nerve cells is damaged. It can cause delayed neurologic symptoms similar to those seen in Lyme disease (LD) patients. Thymus derived T-cells (myelin reactive) migrate ...

Last Updated: 13 Dec 2016

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Established Population of Blacklegged Ticks with High Infection Prevalence for the Lyme Disease Bacterium, Borrelia burgdorferi Sensu Lato, on Corkscrew Island, Kenora District, Ontario.
 

Author(s): John D Scott, Janet E Foley, Kerry L Clark, John F Anderson, Lance A Durden, Jodi M Manord, Morgan L Smith

Journal:

 

We document an established population of blacklegged ticks, Ixodes scapularis, on Corkscrew Island, Kenora District, Ontario, Canada. Primers of the outer surface protein A (OspA) gene, the flagellin (fla) gene, and the flagellin B (flaB) gene were used in the PCR assays to detect ...

Last Updated: 23 Nov 2016

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Lyme disease in Poland in 2014
 

Author(s): Iwona Paradowska-Stankiewicz, Irena Chrześcijańska

Journal: Przegl Epidemiol. ;70(3):395-398.

 

Lyme disease is the most common tick-borne disease, caused by spirochetes of the Borrelia genus transmitted by ticks of the Ixodes genus. Infection caused by Borrelia burgdorferi occur throughout Poland and therefore, according also to ECDC description, the whole country should be ...

Last Updated: 21 Nov 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lyme disease" returned 68 free, full-text review articles on human participants. First 3 results:

Update of the Swiss guidelines on post-treatment Lyme disease syndrome.
 

Author(s): Johannes Nemeth, Enos Bernasconi, Ulrich Heininger, Mohamed Abbas, David Nadal, Carol Strahm, Stefan Erb, Stefan Zimmerli, Hansjakob Furrer, Julie Delaloye, Thierry Kuntzer, Ekkehard Altpeter, Mathias Sturzenegger, Rainer Weber, For The Swiss Society For Infectious Diseases And The Swiss Society For Neurology

Journal:

 

Lyme borreliosis is caused by Borrelia burgdorferi sensu lato infection, which responds well to antibiotic therapy in the overwhelming majority of cases. However, despite adequate antibiotic treatment some patients report persisting symptoms which are commonly summarised as post-treatment ...

Last Updated: 6 Dec 2016

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GIS and Remote Sensing Use in the Exploration of Lyme Disease Epidemiology.
 

Author(s): Esra Ozdenerol

Journal:

 

Given the relatively recent recognition of Lyme disease (LD) by CDC in 1990 as a nationally notifiable infectious condition, the rise of reported human cases every year argues for a better understanding of its geographic scope. The aim of this inquiry was to explore research conducted ...

Last Updated: 4 Dec 2015

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Borrelia miyamotoi Disease: Neither Lyme Disease Nor Relapsing Fever.
 

Author(s): Sam R Telford, Heidi K Goethert, Philip J Molloy, Victor P Berardi, Hanumara Ram Chowdri, Joseph L Gugliotta, Timothy J Lepore

Journal: Clin. Lab. Med.. 2015 Dec;35(4):867-82.

 

Borrelia miyamotoi disease (BMD) is a newly recognized borreliosis globally transmitted by ticks of the Ixodes persulcatus species complex. Once considered to be a tick symbiont with no public health implications, B miyamotoi is increasingly recognized as the agent of a nonspecific ...

Last Updated: 23 Nov 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Xenodiagnosis After Antibiotic Treatment for Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 20 Apr 2017

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Evaluation, Treatment, and Follow-up of Patients With Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 20 Apr 2017

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Last Updated: 28 Mar 2017

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