Lyme Disease

Common Name(s)

Lyme Disease

Lyme Disease is a bacterial infection that is solely the result of being bitten by an infected tick and is the most commong tick-borne disease in the Northern Hemisphere. There are at least three bacteria which can cause Lyme Disease, one being common in North America and two different bacteria being more common in Europe. Early symptoms may include fever, headache, fatigue, depression, and a characteric circular skin rash called erythema migrans (EM). Left untreated, later symptoms may involve the joints, heart, and central nervous system. In most cases, the infection and its symptoms are eliminated by antibiotics, especially if the illness is treated early. Delayed or inadequate treatment can lead to more serious symptoms, which can be disabling and difficult to treat.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme Disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lyme Disease" returned 633 free, full-text research articles on human participants. First 3 results:

Lyme disease.
 

Author(s): Eugene D Shapiro

Journal: N. Engl. J. Med.. 2014 Aug;371(7):684.

 

Last Updated: 14 Aug 2014

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Concerns regarding a new culture method for Borrelia burgdorferi not approved for the diagnosis of Lyme disease.
 

Author(s): Christina Nelson, Sally Hojvat, Barbara Johnson, Jeannine Petersen, Marty Schriefer, C Ben Beard, Lyle Petersen, Paul Mead,

Journal: MMWR Morb. Mortal. Wkly. Rep.. 2014 Apr;63(15):333.

 

In 2005, CDC and the Food and Drug Administration (FDA) issued a warning regarding the use of Lyme disease tests whose accuracy and clinical usefulness have not been adequately established. Often these are laboratory-developed tests (also known as "home brew" tests) that are manufactured ...

Last Updated: 17 Apr 2014

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Evidence for strain-specific immunity in patients treated for early lyme disease.
 

Author(s): Camilo E Khatchikian, Robert B Nadelman, John Nowakowski, Ira Schwartz, Gary P Wormser, Dustin Brisson

Journal: Infect. Immun.. 2014 Apr;82(4):1408-13.

 

Lyme disease, caused by Borrelia burgdorferi, is the most commonly reported vector-borne disease in the United States. Many patients treated for early Lyme disease incur another infection in subsequent years, suggesting that previous exposure to B. burgdorferi may not elicit a protective ...

Last Updated: 20 Mar 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lyme Disease" returned 54 free, full-text review articles on human participants. First 3 results:

Metal-dependent gene regulation in the causative agent of Lyme disease.
 

Author(s): Bryan Troxell, X Frank Yang

Journal:

 

Borrelia burgdorferi (Bb) is the causative agent of Lyme disease transmitted to humans by ticks of the Ixodes spp. Bb is a unique bacterial pathogen because it does not require iron (Fe(2+)) for its metabolism. Bb encodes a ferritin-like Dps homolog called NapA (also called BicA), ...

Last Updated: 3 Dec 2013

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Treatment trials for post-Lyme disease symptoms revisited.
 

Author(s): Mark S Klempner, Phillip J Baker, Eugene D Shapiro, Adriana Marques, Raymond J Dattwyler, John J Halperin, Gary P Wormser

Journal: Am. J. Med.. 2013 Aug;126(8):665-9.

 

The authors of 4 National Institutes of Health-sponsored antibiotic treatment trials of patients with persistent unexplained symptoms despite previous antibiotic treatment of Lyme disease determined that retreatment provides little if any benefit and carries significant risk. Two ...

Last Updated: 26 Jul 2013

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Borrelia burgdorferi infection and Lyme disease in children.
 

Author(s): Susanna Esposito, Samantha Bosis, Caterina Sabatini, Laura Tagliaferri, Nicola Principi

Journal: Int. J. Infect. Dis.. 2013 Mar;17(3):e153-8.

 

Lyme disease is a multisystem disease that frequently affects children. It is caused by a group of related spirochetes, Borrelia burgdorferi sensu lato, that are transmitted by ticks belonging to species of the genus Ixodes. The clinical characteristics of Lyme disease in pediatrics ...

Last Updated: 25 Feb 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Searching for Persistence of Infection in Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease; Borrelia Burgdorferi

 

Last Updated: 14 Mar 2014

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Evaluation, Treatment, and Follow-up of Patients With Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 19 Apr 2014

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Evaluation of Lyme Disease: Clinical, Microbiological and Immunological Characteristics
 

Status: Recruiting

Condition Summary: Chronic Disease; Healthy; Lyme Arthritis; Lyme Disease; Multiple Sclerosis

 

Last Updated: 14 Mar 2014

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