Lyme disease

Common Name(s)

Lyme disease

Lyme disease is an infection caused by three types of Borrellia bacteria. One type is most common in the United States, while the other two types are more common in Europe and Asia. These bacteria are carried by certain ticks; in the United States most commonly the deer tick, in Europe the sheep tick, and in China the taiga tick. An infected tick can pass the bacteria to humans (and other animals) through its bites. However, the transfer of bacteria is believed to only begin after 36-48 hours of the tick being attached.

A characteristic circular rash often develops around the tick bite within 3-30 days and is diagnostic, meaning treatment should begin immediately. Sometimes the rash appears like a bull’s-eye, other times it is a solid red patch, and sometimes the rash does not occur exactly at the site of the tick bite. Other early symptoms include flu like symptoms such as fever, chills, and body aches. Laboratory blood tests are not considered reliable until at least one month after becoming infected through a tick bite. Therefore, it is important if you have flu like symptoms with or without a rash to let your doctor know you have been bitten by a tick within a month’s time.

As symptoms progress, an individual may have a stiff neck, severe fatigue, tingling sensation in the hands or feet, or facial paralysis. Left untreated, later symptoms may involve the joints, heart, and central nervous system. In most cases, the infection and its symptoms are eliminated by antibiotics, especially if the illness is treated early. Delayed or inadequate treatment can lead to more serious symptoms, which can be disabling and difficult to treat. If you or a family member has been diagnosed with Lyme disease, talk to your doctor about the most current treatment options.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme disease" for support, advocacy or research.

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American Lyme Disease Foundation

The American Lyme Disease Foundation, Inc. is dedicated to the prevention, diagnosis and treatment of Lyme disease. The Foundation plays a key role in providing reliable and scientifically accurate information to the public, medical community and government agencies about Lyme disease and its effects on human health and quality of life.

Last Updated: 7 Jan 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Lyme disease" for support, advocacy or research.

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American Lyme Disease Foundation

The American Lyme Disease Foundation, Inc. is dedicated to the prevention, diagnosis and treatment of Lyme disease. The Foundation plays a key role in providing reliable and scientifically accurate information to the public, medical community and government agencies about Lyme disease and its effects on human health and quality of life.

http://www.aldf.com

Last Updated: 7 Jan 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Lyme disease" returned 669 free, full-text research articles on human participants. First 3 results:

Call for more Lyme disease research.
 

Author(s): Carolyn Brown

Journal: CMAJ. 2017 09;189(38):E1218.

 

Last Updated: 26 Sep 2017

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Serious Bacterial Infections Acquired During Treatment of Patients Given a Diagnosis of Chronic Lyme Disease - United States.
 

Author(s): Natalie S Marzec, Christina Nelson, Paul Ravi Waldron, Brian G Blackburn, Syed Hosain, Tara Greenhow, Gary M Green, Catherine Lomen-Hoerth, Marjorie Golden, Paul S Mead

Journal:

 

The term "chronic Lyme disease" is used by some health care providers as a diagnosis for various constitutional, musculoskeletal, and neuropsychiatric symptoms (1,2). Patients with a diagnosis of chronic Lyme disease have been provided a wide range of medications as treatment, including ...

Last Updated: 15 Jun 2017

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Expansion of the Lyme Disease Vector Ixodes Scapularis in Canada Inferred from CMIP5 Climate Projections.
 

Author(s): Michelle McPherson, Almudena García-García, Francisco José Cuesta-Valero, Hugo Beltrami, Patti Hansen-Ketchum, Donna MacDougall, Nicholas Hume Ogden

Journal:

 

A number of studies have assessed possible climate change impacts on the Lyme disease vector, Ixodes scapularis. However, most have used surface air temperature from only one climate model simulation and/or one emission scenario, representing only one possible climate future.

Last Updated: 9 Jun 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Lyme disease" returned 72 free, full-text review articles on human participants. First 3 results:

Interferon-γ-induced protein 10 in Lyme disease.
 

Author(s): P Fallahi, G Elia, A Bonatti

Journal: Clin Ter. ;168(2):e146-e150.

 

Lyme disease is an infectious disease caused by bacteria of the Borrelia type, that affects about 300,000 people a year in the USA and 65,000 people a year in Europe. Borrelia infection, and Lyme disease, following occupational exposure has been frequently reported in USA, Europe ...

Last Updated: 6 Apr 2017

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The Accuracy of Diagnostic Tests for Lyme Disease in Humans, A Systematic Review and Meta-Analysis of North American Research.
 

Author(s): Lisa A Waddell, Judy Greig, Mariola Mascarenhas, Shannon Harding, Robbin Lindsay, Nicholas Ogden

Journal:

 

There has been an increasing incidence of Lyme disease (LD) in Canada and the United States corresponding to the expanding range of the Ixodes tick vector and Lyme disease agent (Borrelia burgdorferi sensu stricto). There are many diagnostic tests for LD available in North America, ...

Last Updated: 21 Dec 2016

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Update of the Swiss guidelines on post-treatment Lyme disease syndrome.
 

Author(s): Johannes Nemeth, Enos Bernasconi, Ulrich Heininger, Mohamed Abbas, David Nadal, Carol Strahm, Stefan Erb, Stefan Zimmerli, Hansjakob Furrer, Julie Delaloye, Thierry Kuntzer, Ekkehard Altpeter, Mathias Sturzenegger, Rainer Weber, For The Swiss Society For Infectious Diseases And The Swiss Society For Neurology

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Lyme borreliosis is caused by Borrelia burgdorferi sensu lato infection, which responds well to antibiotic therapy in the overwhelming majority of cases. However, despite adequate antibiotic treatment some patients report persisting symptoms which are commonly summarised as post-treatment ...

Last Updated: 6 Dec 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Xenodiagnosis After Antibiotic Treatment for Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 14 Nov 2017

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Evaluation, Treatment, and Follow-up of Patients With Lyme Disease
 

Status: Recruiting

Condition Summary: Lyme Disease

 

Last Updated: 5 Oct 2017

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Last Updated: 26 Sep 2017

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