Thyroid Cancer

Common Name(s)

Thyroid Cancer

Thyroid cancer occurs in the cells of the thyroid. The thyroid is responsible for producing hormones that regulate heart rate, blood pressure, body temperature, and weight. Typically, in the early stages of thyroid cancer, there are no symptoms. However, as the cancer progresses one may have the following symptoms: a lump that can be felt through the skin on one’s neck, changes to one’s voice, difficulty swallowing, pain in neck and throat, or swollen lymph nodes in the neck. Thyroid cancer remains relatively rare in the United States, but is becoming more common as new technology enables doctors to find small thyroid cancers that may not have been detected previously. Treatment options are dependent on the individual’s type and stage of thyroid cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

Last Updated: 21 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

http://www.thyroid-cancer-forum-uk.org

Last Updated: 21 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Cancer" returned 1352 free, full-text research articles on human participants. First 3 results:

Lenvatinib in radioiodine-refractory thyroid cancer.
 

Author(s): Martin Schlumberger, Makoto Tahara, Lori J Wirth

Journal: N. Engl. J. Med.. 2015 May;372(19):1868.

 

Last Updated: 7 May 2015

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Chemotherapy for anaplastic thyroid cancer using docetaxel and cisplatin: report of eight cases.
 

Author(s): Akira Seto, Iwao Sugitani, Kazuhisa Toda, Kazuyoshi Kawabata, Shunji Takahashi, Takashi Saotome

Journal: Surg. Today. 2015 Feb;45(2):221-6.

 

Anaplastic thyroid carcinoma has a dismal prognosis and lacks an established therapeutic strategy. We have recently conducted chemotherapy with docetaxel and cisplatin as part of multimodal treatment for eight patients with anaplastic thyroid carcinoma. Docetaxel (75 mg/m2) and cisplatin ...

Last Updated: 2 Mar 2015

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Lenvatinib versus placebo in radioiodine-refractory thyroid cancer.
 

Author(s): Martin Schlumberger, Makoto Tahara, Lori J Wirth, Bruce Robinson, Marcia S Brose, Rossella Elisei, Mouhammed Amir Habra, Kate Newbold, Manisha H Shah, Ana O Hoff, Andrew G Gianoukakis, Naomi Kiyota, Matthew H Taylor, Sung-Bae Kim, Monika K Krzyzanowska, Corina E Dutcus, Begoña de las Heras, Junming Zhu, Steven I Sherman

Journal: N. Engl. J. Med.. 2015 Feb;372(7):621-30.

 

Lenvatinib, an oral inhibitor of vascular endothelial growth factor receptors 1, 2, and 3, fibroblast growth factor receptors 1 through 4, platelet-derived growth factor receptor α, RET, and KIT, showed clinical activity in a phase 2 study involving patients with differentiated thyroid ...

Last Updated: 12 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Cancer" returned 228 free, full-text review articles on human participants. First 3 results:

Thyroid cancer in systemic lupus erythematosus: a meta analysis.
 

Author(s): Min Zhang, Xiao-Mei Li, Guo-Sheng Wang, Long Qian, Jin-Hui Tao, Yan Ma, Xiang-Pei Li

Journal:

 

Considering inconclusive and heterogenous results, the aim of this study was to investigate the risk of thyroid cancer in systemic lupus erythematosus (SLE) by a quantitatively systematic review with meta-analysis.

Last Updated: 22 Oct 2014

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Testicular and inguinal lymph node metastases of medullary thyroid cancer: a case report and review of the literature.
 

Author(s): Marialuisa Appetecchia, Agnese Barnabei, Vincenzo Pompeo, Steno Sentinelli, Roberto Baldelli, Salvatore Maria Corsello, Francesco Torino

Journal:

 

The involvement of the testis by metastatic medullary thyroid carcinoma has never been described before. We describe the first case of metastatic medullary thyroid carcinoma affecting testis and inguinal lymph nodes.

Last Updated: 5 Nov 2014

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Current controversies in the initial post-surgical radioactive iodine therapy for thyroid cancer: a narrative review.
 

Author(s): Ralph Blumhardt, Ely A Wolin, William T Phillips, Umber A Salman, Ronald C Walker, Brendan C Stack, Darlene Metter

Journal: Endocr. Relat. Cancer. 2014 ;21(6):R473-84.

 

Differentiated thyroid cancer (DTC) is the most common endocrine malignancy and the fifth most common cancer in women. DTC therapy requires a multimodal approach, including surgery, which is beyond the scope of this paper. However, for over 50 years, the post-operative management ...

Last Updated: 30 Oct 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer
 

Status: Recruiting

Condition Summary: Follicular Thyroid Cancer; Insular Thyroid Cancer; Papillary Thyroid Cancer; Recurrent Thyroid Cancer

 

Last Updated: 19 Aug 2015

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A Phase II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer
 

Status: Recruiting

Condition Summary: Anaplastic Thyroid Cancer; Thyroid Cancer

 

Last Updated: 28 Jul 2015

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Nintedanib(BIBF1120) in Thyroid Cancer
 

Status: Recruiting

Condition Summary: Medullary Thyroid Cancer (MTC); Differentiated Thyroid Cancer (DTC)

 

Last Updated: 16 Jun 2014

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