Thyroid Cancer

Common Name(s)

Thyroid Cancer

Thyroid cancer occurs in the cells of the thyroid. The thyroid is responsible for producing hormones that regulate heart rate, blood pressure, body temperature, and weight. Typically, in the early stages of thyroid cancer, there are no symptoms. However, as the cancer progresses one may have the following symptoms: a lump that can be felt through the skin on one’s neck, changes to one’s voice, difficulty swallowing, pain in neck and throat, or swollen lymph nodes in the neck. Thyroid cancer remains relatively rare in the United States, but is becoming more common as new technology enables doctors to find small thyroid cancers that may not have been detected previously. Treatment options are dependent on the individual’s type and stage of thyroid cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

Last Updated: 21 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

http://www.thyroid-cancer-forum-uk.org

Last Updated: 21 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Cancer" returned 1727 free, full-text research articles on human participants. First 3 results:

Radiation-Induced Well-Differentiated Thyroid Cancer: Disease Characteristics and Survival.
 

Author(s): Yuval Nachalon, Ohad Hilly, Karl Segal, Eyal Raveh, Dania Hirsch, Eyal Robenshtok, Ilan Shimon, Jacob Shvero, Carlos Benbassat, Aron Popovtzer

Journal: Isr. Med. Assoc. J.. 2016 Feb;18(2):90-4.

 

Radiation exposure is a well-known risk factor for well-differentiated thyroid cancer (WDTC). However, disease characteristics, optimal treatment, time from exposure to disease appearance, and the effect of age at initial exposure on the outcome have yet to be determined.

Last Updated: 16 Mar 2016

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Clinical Outcome of (131)I Therapy in Differentiated Thyroid Cancer with Preablative Thyroglobulin below 10 ng/ml.
 

Author(s): Xin-feng Liu, Jiao Li, Teng Zhao, Min Hou, Hui Li, Jun Liang, Yan-song Lin

Journal: Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2016 Feb;38(1):88-92.

 

To investigate the clinical outcome of (131)I therapy in differentiated thyroid cancer (DTC) with preablative stimulated thyroglobulin (ps-Tg) below 10 ng/ml and the value of ps-Tg for predicting clinical outcome.

Last Updated: 9 Mar 2016

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Optimal Cut-Off Values of Lymph Node Ratio Predicting Recurrence in Papillary Thyroid Cancer.
 

Author(s): Seul Gi Lee, Joon Ho, Jung Bum Choi, Tae Hyung Kim, Min Jhi Kim, Eun Jeong Ban, Cho Rok Lee, Sang-Wook Kang, Jong Ju Jeong, Kee-Hyun Nam, Sang Geun Jung, Young Suk Jo, Jandee Lee, Woong Youn Chung

Journal: Medicine (Baltimore). 2016 Feb;95(5):e2692.

 

Regional lymph node (LN) metastasis has a significant impact for prediction of recurrence in patients with papillary thyroid cancers (PTC); however, the prognostic value of the lymph node ratio (LNR), which is defined as the ratio of the number of metastatic LNs to the total number ...

Last Updated: 5 Feb 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Cancer" returned 257 free, full-text review articles on human participants. First 3 results:

Lenvatinib: Role in thyroid cancer and other solid tumors.
 

Author(s): Maria E Cabanillas, Mouhammed Amir Habra

Journal: Cancer Treat. Rev.. 2016 Jan;42():47-55.

 

Despite recent breakthroughs in treatment of advanced thyroid cancers, prognoses remain poor. Treatment of advanced, progressive disease remains challenging, with limited treatment options. Small-molecule tyrosine kinase inhibitors, including vandetanib, cabozantinib, sorafenib, and ...

Last Updated: 29 Dec 2015

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ENDOCRINE TUMOURS: Genetic predictors of thyroid cancer outcome.
 

Author(s): Catarina Tavares, Miguel Melo, José Manuel Cameselle-Teijeiro, Paula Soares, Manuel Sobrinho-Simões

Journal: Eur. J. Endocrinol.. 2016 Apr;174(4):R117-26.

 

Genetic predictors of outcome are reviewed in the context of a disease--cancer--that can be (too) simplistically described as a 'successful, invasive clone of our own tissues'. Context has many faces that determine a thyroid cancer patient's outcome beyond the influence of genetic ...

Last Updated: 23 Feb 2016

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MECHANISMS IN ENDOCRINOLOGY: MicroRNA in diagnostics and therapy of thyroid cancer.
 

Author(s): Anna Wójcicka, Monika Kolanowska, Krystian Jażdżewski

Journal: Eur. J. Endocrinol.. 2016 Mar;174(3):R89-98.

 

MicroRNAs, short non-coding regulators of the gene expression, are subjects of numerous investigations assessing their potential use in the diagnostics and management of human diseases. In this review, we focus on studies that analyze the utility of microRNAs as novel diagnostic and ...

Last Updated: 16 Jan 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

A Phase II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer
 

Status: Recruiting

Condition Summary: Anaplastic Thyroid Cancer; Thyroid Cancer

 

Last Updated: 8 Mar 2016

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Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer
 

Status: Recruiting

Condition Summary: Follicular Thyroid Cancer; Insular Thyroid Cancer; Papillary Thyroid Cancer; Recurrent Thyroid Cancer

 

Last Updated: 16 Mar 2016

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Nintedanib(BIBF1120) in Thyroid Cancer
 

Status: Recruiting

Condition Summary: Medullary Thyroid Cancer (MTC); Differentiated Thyroid Cancer (DTC)

 

Last Updated: 6 Apr 2016

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