Thyroid Cancer

Common Name(s)

Thyroid Cancer

Thyroid cancer occurs in the cells of the thyroid. The thyroid is responsible for producing hormones that regulate heart rate, blood pressure, body temperature, and weight. Typically, in the early stages of thyroid cancer, there are no symptoms. However, as the cancer progresses one may have the following symptoms: a lump that can be felt through the skin on one’s neck, changes to one’s voice, difficulty swallowing, pain in neck and throat, or swollen lymph nodes in the neck. Thyroid cancer remains relatively rare in the United States, but is becoming more common as new technology enables doctors to find small thyroid cancers that may not have been detected previously. Treatment options are dependent on the individual’s type and stage of thyroid cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

Last Updated: 21 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

http://www.thyroid-cancer-forum-uk.org

Last Updated: 21 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Cancer" returned 1663 free, full-text research articles on human participants. First 3 results:

Radiation-Induced Well-Differentiated Thyroid Cancer: Disease Characteristics and Survival.
 

Author(s): Yuval Nachalon, Ohad Hilly, Karl Segal, Eyal Raveh, Dania Hirsch, Eyal Robenshtok, Ilan Shimon, Jacob Shvero, Carlos Benbassat, Aron Popovtzer

Journal: Isr. Med. Assoc. J.. 2016 Feb;18(2):90-4.

 

Radiation exposure is a well-known risk factor for well-differentiated thyroid cancer (WDTC). However, disease characteristics, optimal treatment, time from exposure to disease appearance, and the effect of age at initial exposure on the outcome have yet to be determined.

Last Updated: 16 Mar 2016

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Clinical utility of RAS mutations in thyroid cancer: a blurred picture now emerging clearer.
 

Author(s): Mingzhao Xing

Journal:

 

RAS mutations play an important role in thyroid tumorigenesis. Considerable effort has been made in the last decade to apply RAS mutations as molecular markers to the clinical management of thyroid nodules and thyroid cancer. Yet, for the low diagnostic sensitivities and specificities ...

Last Updated: 28 Jan 2016

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South Korea's Thyroid-Cancer "Epidemic"--Turning the Tide.
 

Author(s): Hyeong Sik Ahn, H Gilbert Welch

Journal: N. Engl. J. Med.. 2015 Dec;373(24):2389-90.

 

Last Updated: 24 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Cancer" returned 251 free, full-text review articles on human participants. First 3 results:

Selective use of vandetanib in the treatment of thyroid cancer.
 

Author(s): Poupak Fallahi, Flavia Di Bari, Silvia Martina Ferrari, Roberto Spisni, Gabriele Materazzi, Paolo Miccoli, Salvatore Benvenga, Alessandro Antonelli

Journal:

 

Vandetanib is a once-daily orally available tyrosine kinase inhibitor that works by blocking RET (REarranged during Transfection), vascular endothelial growth factor receptor (VEGFR-2, VEGFR-3), and epidermal growth factor receptor and to a lesser extent VEGFR-1, which are important ...

Last Updated: 14 Jul 2015

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THERAPY OF ENDOCRINE DISEASE: Central neck dissection: a step forward in the treatment of papillary thyroid cancer.
 

Author(s): Antonio Sitges-Serra, Leyre Lorente, Germán Mateu, Juan J Sancho

Journal: Eur. J. Endocrinol.. 2015 Dec;173(6):R199-206.

 

Since its introduction in the '70s and '80s, CND for papillary cancer is here to stay. Compartment VI should always be explored during surgery for papillary thyroid carcinoma (PTC) for obvious lymph node metastases. These can be easily spotted by an experienced surgeon or, eventually, ...

Last Updated: 27 Oct 2015

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Molecular Assays in Cytopathology for Thyroid Cancer.
 

Author(s): Pablo Valderrabano, Victor E Zota, Bryan McIver, Domenico Coppola, Marino E Leon

Journal: Cancer Control. 2015 Apr;22(2):152-7.

 

Despite lack of adequate, validated, independently performed clinical studies, several molecular tests are commercially available on the market and are being used on indeterminate thyroid nodules to guide patient-care decisions.

Last Updated: 13 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer
 

Status: Recruiting

Condition Summary: Follicular Thyroid Cancer; Insular Thyroid Cancer; Papillary Thyroid Cancer; Recurrent Thyroid Cancer

 

Last Updated: 16 Mar 2016

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A Phase II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer
 

Status: Recruiting

Condition Summary: Anaplastic Thyroid Cancer; Thyroid Cancer

 

Last Updated: 8 Mar 2016

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Nintedanib(BIBF1120) in Thyroid Cancer
 

Status: Recruiting

Condition Summary: Medullary Thyroid Cancer (MTC); Differentiated Thyroid Cancer (DTC)

 

Last Updated: 6 Apr 2016

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