Thyroid Cancer

Common Name(s)

Thyroid Cancer

Thyroid cancer occurs in the cells of the thyroid. The thyroid is responsible for producing hormones that regulate heart rate, blood pressure, body temperature, and weight. Typically, in the early stages of thyroid cancer, there are no symptoms. However, as the cancer progresses one may have the following symptoms: a lump that can be felt through the skin on one’s neck, changes to one’s voice, difficulty swallowing, pain in neck and throat, or swollen lymph nodes in the neck. Thyroid cancer remains relatively rare in the United States, but is becoming more common as new technology enables doctors to find small thyroid cancers that may not have been detected previously. Treatment options are dependent on the individual’s type and stage of thyroid cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

Last Updated: 21 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Logo
Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

http://www.thyroid-cancer-forum-uk.org

Last Updated: 21 Jan 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Cancer" returned 1234 free, full-text research articles on human participants. First 3 results:

A Phase II trial of axitinib in patients with various histologic subtypes of advanced thyroid cancer: long-term outcomes and pharmacokinetic/pharmacodynamic analyses.
 

Author(s): E E W Cohen, M Tortorici, S Kim, A Ingrosso, Y K Pithavala, P Bycott

Journal: Cancer Chemother. Pharmacol.. 2014 Dec;74(6):1261-70.

 

Axitinib, a potent and selective second-generation inhibitor of vascular endothelial growth factor receptors, has shown activity in advanced thyroid cancer in a Phase II study. We report updated overall survival and pharmacokinetic/pharmacodynamic (PK/PD) analyses from the study.

Last Updated: 21 Nov 2014

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Response and acquired resistance to everolimus in anaplastic thyroid cancer.
 

Author(s): Nikhil Wagle, Brian C Grabiner, Eliezer M Van Allen, Ali Amin-Mansour, Amaro Taylor-Weiner, Mara Rosenberg, Nathanael Gray, Justine A Barletta, Yanan Guo, Scott J Swanson, Daniel T Ruan, Glenn J Hanna, Robert I Haddad, Gad Getz, David J Kwiatkowski, Scott L Carter, David M Sabatini, Pasi A Jänne, Levi A Garraway, Jochen H Lorch

Journal: N. Engl. J. Med.. 2014 Oct;371(15):1426-33.

 

Everolimus, an inhibitor of the mammalian target of rapamycin (mTOR), is effective in treating tumors harboring alterations in the mTOR pathway. Mechanisms of resistance to everolimus remain undefined. Resistance developed in a patient with metastatic anaplastic thyroid carcinoma ...

Last Updated: 9 Oct 2014

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Thyroid cancer study among Ukrainian children exposed to radiation after the Chornobyl accident: improved estimates of the thyroid doses to the cohort members.
 

Author(s): Ilya Likhtarov, Lina Kovgan, Sergii Masiuk, Mykola Talerko, Mykola Chepurny, Olga Ivanova, Valentina Gerasymenko, Zulfira Boyko, Paul Voillequé, Vladimir Drozdovitch, André Bouville

Journal: Health Phys. 2014 Mar;106(3):370-96.

 

In collaboration with the Ukrainian Research Center for Radiation Medicine, the U.S. National Cancer Institute initiated a cohort study of children and adolescents exposed to Chornobyl fallout in Ukraine to better understand the long-term health effects of exposure to radioactive ...

Last Updated: 11 Sep 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Cancer" returned 219 free, full-text review articles on human participants. First 3 results:

Anaplastic thyroid cancer: the addition of systemic chemotherapy to radiotherapy led to an observed improvement in survival--a single centre experience and review of the literature.
 

Author(s): Natalie M Lowe, Sean Loughran, Nicholas J Slevin, Beng K Yap

Journal: ScientificWorldJournal. 2014 ;2014():674583.

 

Anaplastic thyroid carcinoma (ATC) is rare yet accounts for up to 50% of all thyroid cancer deaths. This study reviews outcomes of patients with confirmed ATC referred to a tertiary oncology centre plus reviews the literature to explore how poor outcomes may be improved.

Last Updated: 3 Sep 2014

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Estrogen and its role in thyroid cancer.
 

Author(s): Michael Derwahl, Diana Nicula

Journal: Endocr. Relat. Cancer. 2014 Oct;21(5):T273-83.

 

Proliferative thyroid diseases are more prevalent in females than in males. Upon the onset of puberty, the incidence of thyroid cancer increases in females only and declines again after menopause. Estrogen is a potent growth factor both for benign and malignant thyroid cells that ...

Last Updated: 6 Sep 2014

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Low risk papillary thyroid cancer.
 

Author(s): Juan P Brito, Ian D Hay, John C Morris

Journal:

 

Thyroid cancer is one of the fastest growing diagnoses; more cases of thyroid cancer are found every year than all leukemias and cancers of the liver, pancreas, and stomach. Most of these incident cases are papillary in origin and are both small and localized. Patients with these ...

Last Updated: 17 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer
 

Status: Recruiting

Condition Summary: Follicular Thyroid Cancer; Insular Thyroid Cancer; Papillary Thyroid Cancer; Recurrent Thyroid Cancer

 

Last Updated: 2 Mar 2015

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Pre-Operative Nodal Staging of Thyroid Cancer Using Ultra-Small Superparamagnetic Iron Oxide Magnetic Resonance Imaging (USPIO MRI): Preliminary Study
 

Status: Recruiting

Condition Summary: Papillary Carcinoma of Thyroid Metastatic to Regional Lymph Node; Metastatic Medullary Thyroid Cancer; Follicular Thyroid Cancer Lymph Node Metastasis

 

Last Updated: 22 Aug 2013

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A Phase II Study of MLN0128 in Metastatic Anaplastic Thyroid Cancer
 

Status: Not yet recruiting

Condition Summary: Anaplastic Thyroid Cancer; Thyroid Cancer

 

Last Updated: 17 Sep 2014

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