Thyroid Cancer

Common Name(s)

Thyroid Cancer

Thyroid cancer occurs in the cells of the thyroid. The thyroid is responsible for producing hormones that regulate heart rate, blood pressure, body temperature, and weight. Typically, in the early stages of thyroid cancer, there are no symptoms. However, as the cancer progresses one may have the following symptoms: a lump that can be felt through the skin on one’s neck, changes to one’s voice, difficulty swallowing, pain in neck and throat, or swollen lymph nodes in the neck. Thyroid cancer remains relatively rare in the United States, but is becoming more common as new technology enables doctors to find small thyroid cancers that may not have been detected previously. Treatment options are dependent on the individual’s type and stage of thyroid cancer.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

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Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

Last Updated: 21 Jan 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Thyroid Cancer" for support, advocacy or research.

Logo
Thyroid Cancer Forum-UK

On line information for patients on thyroid cancer including: Background information on the thyroid gland Incidence and Risk factors Symptoms Types of thyroid cancer Diagnosis and staging investigations Treatment: surgery, thyroxine, radioiodine, mIBG, radiotherapy Follow up Prognosis Clinical Trials Electronic links to other sites for information and support

http://www.thyroid-cancer-forum-uk.org

Last Updated: 21 Jan 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Thyroid Cancer" returned 1131 free, full-text research articles on human participants. First 3 results:

Overdiagnosing thyroid cancer. What's in a name?
 

Author(s):

Journal: Manag Care. 2014 May;23(5):25.

 

Last Updated: 14 Jul 2014

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Thioredoxin interacting protein (TXNIP) is a novel tumor suppressor in thyroid cancer.
 

Author(s): Jennifer A Morrison, Laura A Pike, Sharon B Sams, Vibha Sharma, Qiong Zhou, Jill J Severson, Aik-Choon Tan, William M Wood, Bryan R Haugen

Journal:

 

Thyroid cancer is the most common endocrine malignancy, and many patients with metastatic differentiated thyroid cancer (DTC), poorly differentiated thyroid cancer (PDTC), and anaplastic thyroid cancer (ATC) fail to respond to conventional therapies, resulting in morbidity and mortality. ...

Last Updated: 28 Mar 2014

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Identification of the transforming STRN-ALK fusion as a potential therapeutic target in the aggressive forms of thyroid cancer.
 

Author(s): Lindsey M Kelly, Guillermo Barila, Pengyuan Liu, Viktoria N Evdokimova, Sumita Trivedi, Federica Panebianco, Manoj Gandhi, Sally E Carty, Steven P Hodak, Jianhua Luo, Sanja Dacic, Yan P Yu, Marina N Nikiforova, Robert L Ferris, Daniel L Altschuler, Yuri E Nikiforov

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Mar;111(11):4233-8.

 

Thyroid cancer is a common endocrine malignancy that encompasses well-differentiated as well as dedifferentiated cancer types. The latter tumors have high mortality and lack effective therapies. Using a paired-end RNA-sequencing approach, we report the discovery of rearrangements ...

Last Updated: 7 Apr 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Thyroid Cancer" returned 197 free, full-text review articles on human participants. First 3 results:

Low risk papillary thyroid cancer.
 

Author(s): Juan P Brito, Ian D Hay, John C Morris

Journal:

 

Thyroid cancer is one of the fastest growing diagnoses; more cases of thyroid cancer are found every year than all leukemias and cancers of the liver, pancreas, and stomach. Most of these incident cases are papillary in origin and are both small and localized. Patients with these ...

Last Updated: 17 Jun 2014

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Endocrine side-effects of anti-cancer drugs: thyroid effects of tyrosine kinase inhibitors.
 

Author(s): Frédéric Illouz, Doreen Braun, Claire Briet, Ulrich Schweizer, Patrice Rodien

Journal: Eur. J. Endocrinol.. 2014 Sep;171(3):R91-9.

 

Tyrosine kinase inhibitors (TKIs) are currently used by most oncologists. Among their side effects, thyroid dysfunctions are nowadays clearly observed. Whereas changes in thyroid function tests have been originally described with sunitinib, we now know that many TKIs can induce hypothyroidism ...

Last Updated: 23 Jul 2014

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Thyroglobulin measurement using highly sensitive assays in patients with differentiated thyroid cancer: a clinical position paper.
 

Author(s): Luca Giovanella, Penelope M Clark, Luca Chiovato, Leonidas Duntas, Rossella Elisei, Ulla Feldt-Rasmussen, Laurence Leenhardt, Markus Luster, Camilla Schalin-Jäntti, Matthias Schott, Ettore Seregni, Herald Rimmele, Jan Smit, Frederik A Verburg

Journal: Eur. J. Endocrinol.. 2014 Aug;171(2):R33-46.

 

Differentiated thyroid cancer (DTC) is the most common endocrine cancer and its incidence has increased in recent decades. Initial treatment usually consists of total thyroidectomy followed by ablation of thyroid remnants by iodine-131. As thyroid cells are assumed to be the only ...

Last Updated: 25 Jun 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sutent Adjunctive Treatment of Differentiated Thyroid Cancer
 

Status: Recruiting

Condition Summary: Papillary Thyroid Cancer; Follicular Thyroid Cancer; Differentiated Thyroid Cancer

 

Last Updated: 21 May 2014

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Dabrafenib With or Without Trametinib in Treating Patients With Recurrent Thyroid Cancer
 

Status: Recruiting

Condition Summary: Follicular Thyroid Cancer; Insular Thyroid Cancer; Papillary Thyroid Cancer; Recurrent Thyroid Cancer

 

Last Updated: 25 Aug 2014

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Pre-Operative Nodal Staging of Thyroid Cancer Using Ultra-Small Superparamagnetic Iron Oxide Magnetic Resonance Imaging (USPIO MRI): Preliminary Study
 

Status: Recruiting

Condition Summary: Papillary Carcinoma of Thyroid Metastatic to Regional Lymph Node; Metastatic Medullary Thyroid Cancer; Follicular Thyroid Cancer Lymph Node Metastasis

 

Last Updated: 22 Aug 2013

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