Benign Prostatic Hyperplasia

Common Name(s)

Benign Prostatic Hyperplasia

Benign prostatic hyperplasia (BPH) is a noncancerous enlargement of the prostate gland, and is common in older men. Symptoms may include: enlarged prostate, urine retention, slow flow of urine, and need to urinate urgently. BPH typically begins while a man is in his 30's, but usually only causes symptoms after age 50. This condition is very common, half of men over 50 develop symptoms, but only 10% of those affected need medical or surgical intervention. Medical intervention may be needed if the patient develops repeated urinary tract infection, or if the urethra becomes completely blocked.

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Advocacy and Support Organizations

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Benign Prostatic Hyperplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Benign Prostatic Hyperplasia" returned 839 free, full-text research articles on human participants. First 3 results:

Testosterone-induced benign prostatic hyperplasia rat and dog as facile models to assess drugs targeting lower urinary tract symptoms.
 

Author(s): Jing Li, Yanxin Tian, Shimeng Guo, Haifeng Gu, Qianting Yuan, Xin Xie

Journal:

 

Benign prostatic hyperplasia (BPH) is an age-related disease, affecting a majority of elderly men worldwide. Medical management of BPH is an alternative to surgical treatment of this disease. Currently, α1-adrenergic receptor (α1-AR) antagonists are among the first line drugs to ...

Last Updated: 31 Dec 1969

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Oxidative stress parameters in patients with prostate cancer, benign prostatic hyperplasia and asymptomatic inflammatory prostatitis: A prospective controlled study.
 

Author(s): Engin Kaya, Yasar Ozgok, Murat Zor, Ayse Eken, Selahattin Bedir, Onur Erdem, Turgay Ebiloglu, Giray Ergin

Journal: Adv Clin Exp Med. 2017 Oct;26(7):1095-1099.

 

The imbalance between oxidant and reductant mechanisms creates a nidus for the etiopathogenesis of several diseases. In this study, we aimed to compare the oxidative stress (OS) parameters in patients who were diagnosed with prostate cancer (pCa), benign prostatic hyperplasia (BPH) ...

Last Updated: 31 Dec 1969

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Molecular Analysis of the SRD5A1 and SRD5A2 Genes in Patients with Benign Prostatic Hyperplasia with Regard to Metabolic Parameters and Selected Hormone Levels.
 

Author(s): Aleksandra Rył, Iwona Rotter, Anna Grzywacz, Iwona Małecka, Karolina Skonieczna-Żydecka, Katarzyna Grzesiak, Marcin Słojewski, Aleksandra Szylińska, Olimpia Sipak-Szmigiel, Małgorzata Piasecka, Kinga Walczakiewicz, Maria Laszczyńska

Journal:

 

: The etiology of benign prostatic hyperplasia (BPH) has not so far been fully explicated. However, it is assumed that changes in the levels of hormones associated with aging can contribute to the development of prostatic hyperplasia. Dihydrotestosterone combines with the androgen ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Benign Prostatic Hyperplasia" returned 143 free, full-text review articles on human participants. First 3 results:

Contemporary surgical treatment of benign prostatic hyperplasia.
 

Author(s): Ricardo Luís Vita Nunes, Alberto Azoubel Antunes, Davi Souza Constantin

Journal: Rev Assoc Med Bras (1992). 2017 Aug;63(8):711-716.

 

Benign prostatic hyperplasia (BPH) is a common condition in adult men and its incidence increases progressively with aging. It has an important impact on the individual's physical and mental health and its natural progression can lead to serious pathological situations. Although the ...

Last Updated: 31 Dec 1969

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Genetic association between PSA-158G/A polymorphism and the susceptibility of benign prostatic hyperplasia: a meta-analysis.
 

Author(s): Xin-Jun Su, Xian-Tao Zeng, Cheng Fang, Tong-Zu Liu, Xing-Huan Wang

Journal: Oncotarget. 2017 May;8(20):33953-33960.

 

Inconsistency between reported findings on the association of prostate specific antigen (PSA) gene -158G/A polymorphism with benign prostatic hyperplasia (BPH) susceptibility need a meta-analysis to obtain a more accurate conclusion. A systematic search was conducted in electronic ...

Last Updated: 31 Dec 1969

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Acupuncture for benign prostatic hyperplasia: A systematic review and meta-analysis.
 

Author(s): Wei Zhang, Liyan Ma, Brent A Bauer, Zhishun Liu, Yao Lu

Journal:

 

This systematic review and meta-analysis aims to assess the therapeutic and adverse effects of acupuncture for benign prostatic hyperplasia (BPH) in randomized controlled trials (RCTs).

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prostatic Artery Embolization Versus Medical Treatment in Symptomatic Benign Prostatic Hyperplasia
 

Status: Recruiting

Condition Summary: Benign Prostatic Hyperplasia

 

Last Updated: 13 Apr 2017

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Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)
 

Status: Recruiting

Condition Summary: Benign Prostatic Hyperplasia

 

Last Updated: 14 Feb 2018

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Last Updated: 24 Jan 2018

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