Benign Prostatic Hyperplasia

Common Name(s)

Benign Prostatic Hyperplasia

Benign prostatic hyperplasia (BPH) is a noncancerous enlargement of the prostate gland, and is common in older men. Symptoms may include: enlarged prostate, urine retention, slow flow of urine, and need to urinate urgently. BPH typically begins while a man is in his 30's, but usually only causes symptoms after age 50. This condition is very common, half of men over 50 develop symptoms, but only 10% of those affected need medical or surgical intervention. Medical intervention may be needed if the patient develops repeated urinary tract infection, or if the urethra becomes completely blocked.

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Advocacy and Support Organizations

 

Condition Specific Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Benign Prostatic Hyperplasia" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Benign Prostatic Hyperplasia" returned 820 free, full-text research articles on human participants. First 3 results:

Relationship of oestrogen receptor alpha gene polymorphisms with risk for benign prostatic hyperplasia and prostate cancer in Chinese men.
 

Author(s): Zihua Han, Lingzhi Zhang, Rujian Zhu, Lifei Luo, Min Zhu, Lilong Fan, Guanfu Wang

Journal: Medicine (Baltimore). 2017 Mar;96(13):e6473.

 

The relationship of oestrogen receptor with benign prostatic hyperplasia (BPH) and prostate cancer (PC) is not clear at present. This study aimed to investigate the molecular mechanism underlying the occurrence and development of BPH and prostate.Two hundred forty-four PC cases, 260 ...

Last Updated: 29 Mar 2017

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Survivin and NAIP in Human Benign Prostatic Hyperplasia: Protective Role of the Association of Serenoa repens, Lycopene and Selenium from the Randomized Clinical Study.
 

Author(s): Giuseppe Morgia, Antonio Micali, Mariagrazia Rinaldi, Natasha Irrera, Herbert Marini, Domenico Puzzolo, Antonina Pisani, Salvatore Privitera, Giorgio I Russo, Sebastiano Cimino, Antonio Ieni, Vincenzo Trichilo, Domenica Altavilla, Francesco Squadrito, Letteria Minutoli

Journal:

 

Benign prostatic hyperplasia (BPH) treatment includes the apoptosis machinery modulation through the direct inhibition of caspase cascade. We previously demonstrated that Serenoa repens (Ser) with lycopene (Ly) and selenium (Se) reawakened apoptosis by reducing survivin and neuronal ...

Last Updated: 22 Mar 2017

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Calcium - Magnesium imbalance implicated in benign prostatic hyperplasia and restoration by a phytotherapeutic drug - Croton membranaceus Müll.Arg.
 

Author(s): George Awuku Asare, Robert A Ngala, Daniel Afriyie, Samuel Adjei, Adriana Nyarko, Yvonne Anang-Quartey, Bernice Asiedu, Derek Doku, Brodrick Y Amoah, Kennedy Bentum, Iddi Musah, Kensese Mossanda

Journal:

 

Calcium (Ca)- magnesium (Mg) imbalance is implicated in prostate cancer. Ca/Mg ratio increases or decreases with proliferation or apoptosis, respectively. The study examined whether this Ca/Mg imbalance exists in BPH patients and the effect of a phytotherapeutic drug on the Ca/Mg ratio.

Last Updated: 12 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Benign Prostatic Hyperplasia" returned 134 free, full-text review articles on human participants. First 3 results:

[What role does botulinum toxin play in the treatment of benign prostatic hyperplasia?]
 

Author(s): Adil Mazdar, Ali Bedouche, Sinane Zoughari, Ahmed Ibrahimi, Hachem El Sayegh, Ali Iken, Lounis Benslimane, Yassine Nouini

Journal:

 

Botulinum toxin (BT) was first used in urology for the treatment of neuro-urological disorders such as bladder sphincter dyssynergia and incontinence due to neuropathic detrusor overactivity. Its action is now clearly demonstrated and it is now widely used in treating neurogenic neuropathic ...

Last Updated: 3 Feb 2017

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Efficacy and safety of prostate artery embolization on lower urinary tract symptoms related to benign prostatic hyperplasia: a systematic review and meta-analysis.
 

Author(s): Xiao-Yan Wang, Huan-Tao Zong, Yong Zhang

Journal:

 

Prostate artery embolization (PAE) is emerging and is a promising minimally invasive therapy that improves lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH). The purpose of this article was to evaluate the efficacy and safety of PAE on LUTS related to BPH.

Last Updated: 13 Dec 2016

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New medical treatments for lower urinary tract symptoms due to benign prostatic hyperplasia and future perspectives.
 

Author(s): Simone Albisinni, Ibrahim Biaou, Quentin Marcelis, Fouad Aoun, Cosimo De Nunzio, Thierry Roumeguère

Journal:

 

Lower Urinary Tract Symptoms (LUTS) in men are a common clinical problem in urology and have been historically strictly linked to benign prostatic hyperplasia (BPH), which may lead to bladder outlet obstruction (BOO). New molecules have been approved and have entered the urologists' ...

Last Updated: 16 Sep 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Prostatic Artery Embolization Versus Medical Treatment in Symptomatic Benign Prostatic Hyperplasia
 

Status: Recruiting

Condition Summary: Benign Prostatic Hyperplasia

 

Last Updated: 13 Apr 2017

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Last Updated: 31 Jan 2016

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Prostatic Artery Embolization (PAE) for Treatment of Benign Prostatic Hyperplasia (BPH)
 

Status: Recruiting

Condition Summary: Benign Prostatic Hyperplasia (BPH)

 

Last Updated: 1 Jun 2017

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