Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 652 free, full-text research articles on human participants. First 3 results:

Interactions between αv-Integrin and HER2 and Their Role in the Invasive Phenotype of Breast Cancer Cells In Vitro and in Rat Brain.
 

Author(s): Sangeet Lal, Cymon Kersch, Kathleen A Beeson, Y Jeffrey Wu, Leslie L Muldoon, Edward A Neuwelt

Journal:

 

We tested the hypothesis that αv-integrin and the human epidermal growth factor receptor type 2 (HER2) interact with each other in brain trophic metastatic breast cancer cells and influence their invasive phenotype.

Last Updated: 30 Jul 2015

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[Analysis of Survival Predictors in Patients with Lung Cancer and Brain Metastases].
 

Author(s): Shaohua Cui, Hao Bai, Lili Dong, Yizhuo Zhao, Aiqin Gu, Wei Zhang, Yuqing Lou, Liyan Jiang

Journal: Zhongguo Fei Ai Za Zhi. 2015 Jul;18(7):436-42.

 

The prognosis for patients with lung cancer and brain metastases remains poor, with approximately 6 months of survival, despite active measures after treatment. In this study, we determined and analyzed clinical parameters that affect the survival of patients with lung cancer and ...

Last Updated: 18 Jul 2015

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Over Expression of BCL2 and Low Expression of Caspase 8 Related to TRAIL Resistance in Brain Cancer Stem Cells.
 

Author(s): Ling Qi, Kuang Ren, Fang Fang, Dong-Hai Zhao, Ning-Jiang Yang, Yan Li

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(12):4849-52.

 

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) has been investigated as an effective agent to treat various cancers. Cancer stem cells are resistant to TRAIL treatment, but the mechanism of TRAIL resistance remains unknown. In this study, brain cancer stem cells were ...

Last Updated: 12 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 86 free, full-text review articles on human participants. First 3 results:

Anaplastic lymphoma kinase inhibitors in brain metastases from ALK+ non-small cell lung cancer: hitting the target even in the CNS.
 

Author(s): Samuel J Klempner, Sai-Hong Ignatius Ou

Journal: Chin Clin Oncol. 2015 Jun;4(2):20.

 

The paradigm shift occurring in non-small cell lung cancer (NSCLC) is encapsulated by the management of patients harboring oncogenic anaplastic lymphoma kinase (ALK) rearrangements. The unprecedented improvements in patient outcomes resulting from ALK-directed therapy have led to ...

Last Updated: 26 Jun 2015

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Role of HER2 in brain metastasis of breast cancer: a systematic review and meta-analysis.
 

Author(s): Akbar Hedayatizadeh-Omran, Alireza Rafiei, Reza Alizadeh-Navaei, Mohsen Tehrani, Reza Valadan, Kambiz Moradzadeh, Mohammad Panbechi, Seyed Mehdi Taghavi

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(4):1431-4.

 

Breast cancer is one of the most common cancers among women worldwide and the HER2 receptor plays an important role in its development and progression. This systematic review aimed to summarize the role of HER2 in brain metastasis in patients with breast cancer.

Last Updated: 6 Mar 2015

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Emerging strategies for treating brain metastases from breast cancer.
 

Author(s): David P Kodack, Vasileios Askoxylakis, Gino B Ferraro, Dai Fukumura, Rakesh K Jain

Journal: Cancer Cell. 2015 Feb;27(2):163-75.

 

Brain metastasis is an end stage in breast cancer progression. Traditional treatment options have minimal efficacy, and overall survival is on the order of months. The incidence of brain metastatic disease is increasing with the improved management of systemic disease and prolongation ...

Last Updated: 11 Feb 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
 

Status: Not yet recruiting

Condition Summary: Benign Neoplasms, Brain; Brain Cancer; Brain Neoplasms, Benign; Brain Neoplasms, Malignant; Brain Tumor, Primary; Brain Tumor, Recurrent; Brain Tumors; Intracranial Neoplasms; Neoplasms, Brain; Neoplasms, Intracranial; Primary Brain Neoplasms; Primary Malignant Brain Neoplasms; Primary Malignant Brain Tumors; Gliomas; Glioblastoma

 

Last Updated: 30 Oct 2015

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1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
 

Status: Recruiting

Condition Summary: Brain Neoplasms; Brain Cancer; Brain Tumors; Cancer of the Brain; Cancer of Brain; Seizure

 

Last Updated: 5 Apr 2016

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Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
 

Status: Recruiting

Condition Summary: Glioma; Brain Cancer; Brain Tumor; Glioblastoma Multiforme; High Grade Glioma

 

Last Updated: 31 Mar 2016

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