Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 414 free, full-text research articles on human participants. First 3 results:

Human breast cancer metastases to the brain display GABAergic properties in the neural niche.
 

Author(s): Josh Neman, John Termini, Sharon Wilczynski, Nagarajan Vaidehi, Cecilia Choy, Claudia M Kowolik, Hubert Li, Amanda C Hambrecht, Eugene Roberts, Rahul Jandial

Journal: Proc. Natl. Acad. Sci. U.S.A.. 2014 Jan;111(3):984-9.

 

Dispersion of tumors throughout the body is a neoplastic process responsible for the vast majority of deaths from cancer. Despite disseminating to distant organs as malignant scouts, most tumor cells fail to remain viable after their arrival. The physiologic microenvironment of the ...

Last Updated: 22 Jan 2014

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Presence of viral DNA in whole-genome sequencing of brain tumor tissues from the cancer genome atlas.
 

Author(s): E Susan Amirian, Melissa L Bondy, Qianxing Mo, Matthew N Bainbridge, Michael E Scheurer

Journal: J. Virol.. 2014 Jan;88(1):774.

 

Last Updated: 19 Dec 2013

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[Surgical treatment for non-small cell lung cancer patients with synchronous solitary brain metastasis].
 

Author(s): Hao Bai, Baohui Han

Journal: Zhongguo Fei Ai Za Zhi. 2013 Dec;16(12):646-50.

 

Brain metastases are common in non-small cell lung cancer. Usual treatments include radiotherapy and chemotherapy. However, these methods result in poor patient prognosis. The aim of this study is to assess the effectiveness of surgical resection in the multimodality management of ...

Last Updated: 18 Dec 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 57 free, full-text review articles on human participants. First 3 results:

[Advances in diagnosis and treatment of brain metastases from the primary lung cancer].
 

Author(s): Yi Liu, Jun Chen

Journal: Zhongguo Fei Ai Za Zhi. 2013 Jul;16(7):382-6.

 

Lung cancer with brain metastasis was 23% to 65%, and is the most common type in brain metastasis tumors with the poor prognosis. At present, diagnosis and treatment of brain metastases from lung carcinoma and its molecular mechanism have become one hot spot of amount researches. ...

Last Updated: 22 Jul 2013

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Therapeutic nanomedicine for brain cancer.
 

Author(s): Stephany Y Tzeng, Jordan J Green

Journal: Ther Deliv. 2013 Jun;4(6):687-704.

 

Malignant brain cancer treatment is limited by a number of barriers, including the blood-brain barrier, transport within the brain interstitium, difficulties in delivering therapeutics specifically to tumor cells, the highly invasive quality of gliomas and drug resistance. As a result, ...

Last Updated: 6 Jun 2013

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Cancer 'survivor-care': II. Disruption of prefrontal brain activation top-down control of working memory capacity as possible mechanism for chemo-fog/brain (chemotherapy-associated cognitive impairment).
 

Author(s): R B Raffa

Journal: J Clin Pharm Ther. 2013 Aug;38(4):265-8.

 

Cancer chemotherapy-associated cognitive impairments (termed 'chemo-fog' or 'chemo-brain'), particularly in memory, have been self-reported or identified in cancer survivors previously treated with chemotherapy. Although a variety of deficits have been detected, a consistent theme ...

Last Updated: 8 Jul 2013

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
 

Status: Recruiting

Condition Summary: Benign Neoplasms, Brain; Brain Cancer; Brain Neoplasms, Benign; Brain Neoplasms, Malignant; Brain Tumor, Primary; Brain Tumor, Recurrent; Brain Tumors; Intracranial Neoplasms; Neoplasms, Brain; Neoplasms, Intracranial; Primary Brain Neoplasms; Primary Malignant Brain Neoplasms; Primary Malignant Brain Tumors; Gliomas; Glioblastoma

 

Last Updated: 11 Jun 2014

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Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
 

Status: Recruiting

Condition Summary: Glioma; Brain Cancer; Brain Tumor; Glioblastoma Multiforme; High Grade Glioma

 

Last Updated: 24 Jul 2014

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Study of a Drug [DCVax®-L] to Treat Newly Diagnosed GBM Brain Cancer
 

Status: Recruiting

Condition Summary: Glioblastoma Multiforme; Glioblastoma; GBM; Grade IV Astrocytoma; Glioma; Brain Cancer; Brain Tumor

 

Last Updated: 12 Jun 2014

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