Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 491 free, full-text research articles on human participants. First 3 results:

Regional brain glucose metabolism and neurocognitive function in adult survivors of childhood cancer treated with cranial radiation.
 

Author(s): Kevin R Krull, Satoshi Minoshima, Michelle Edelmann, Brannon Morris, Noah D Sabin, Tara M Brinkman, Gregory T Armstrong, Leslie L Robison, Melissa M Hudson, Barry Shulkin

Journal: J. Nucl. Med.. 2014 Nov;55(11):1805-10.

 

The objective of this study was to examine associations between regional brain metabolism, as measured by (18)F-FDG PET, and neurocognitive outcomes in adult survivors of childhood acute lymphoblastic leukemia (ALL) treated with cranial radiation.

Last Updated: 4 Nov 2014

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The E1 copper binding domain of full-length amyloid precursor protein mitigates copper-induced growth inhibition in brain metastatic prostate cancer DU145 cells.
 

Author(s): Mallory Gough, Sophee Blanthorn-Hazell, Craig Delury, Edward Parkin

Journal: Biochem. Biophys. Res. Commun.. 2014 Oct;453(4):741-7.

 

Copper plays an important role in the aetiology and growth of tumours and levels of the metal are increased in the serum and tumour tissue of patients affected by a range of cancers including prostate cancer (PCa). The molecular mechanisms that enable cancer cells to proliferate in ...

Last Updated: 29 Jan 2015

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Stereotactic radiotherapy in epithelial ovarian cancer brain metastases patients.
 

Author(s): Agata Celejewska, Andrzej Tukiendorf, Leszek Miszczyk, Krzysztof Składowski, Jerzy Wydmański, Krystyna Trela-Janus

Journal:

 

In this report we present the results of the retrospective (survival and classification) analyses of possible prognostic factors prolonging survival in epithelial ovarian cancer brain metastases patients after stereotactic radiotherapy. We focus on a wide range of available predictors ...

Last Updated: 10 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 68 free, full-text review articles on human participants. First 3 results:

Updates on the management of breast cancer brain metastases.
 

Author(s): Elgene Lim, Nancy U Lin

Journal: Oncology (Williston Park, N.Y.). 2014 Jul;28(7):572-8.

 

Breast cancer brain metastases (BCBMs) are common in patients with advanced disease. Breast cancer subtype and performance status are the major determinants of the course of the disease and survival time following a diagnosis of brain metastasis. Unique challenges specific to the ...

Last Updated: 26 Aug 2014

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Rationale for the use of upfront whole brain irradiation in patients with brain metastases from breast cancer.
 

Author(s): Agnes V Tallet, David Azria, Emilie Le Rhun, Fabrice Barlesi, Antoine F Carpentier, Antony Gonçalves, Sophie Taillibert, Frédéric Dhermain, Jean-Philippe Spano, Philippe Metellus

Journal:

 

Breast cancer is the second most common cause of brain metastases and deserves particular attention in relation to current prolonged survival of patients with metastatic disease. Advances in both systemic therapies and brain local treatments (surgery and stereotactic radiosurgery) ...

Last Updated: 12 May 2014

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It takes two to tango, a dance between the cells of origin and cancer stem cells in the Drosophila larval brain.
 

Author(s): Derek H Janssens, Cheng-Yu Lee

Journal: Semin. Cell Dev. Biol.. 2014 Apr;28():63-9.

 

During malignant transformation the cells of origin give rise to cancer stem cells which possess the capacity to undergo limitless rounds of self-renewing division, regenerating themselves while producing more tumor cells. Within normal tissues, a limitless self-renewal capacity is ...

Last Updated: 27 May 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
 

Status: Recruiting

Condition Summary: Benign Neoplasms, Brain; Brain Cancer; Brain Neoplasms, Benign; Brain Neoplasms, Malignant; Brain Tumor, Primary; Brain Tumor, Recurrent; Brain Tumors; Intracranial Neoplasms; Neoplasms, Brain; Neoplasms, Intracranial; Primary Brain Neoplasms; Primary Malignant Brain Neoplasms; Primary Malignant Brain Tumors; Gliomas; Glioblastoma

 

Last Updated: 23 Dec 2014

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1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
 

Status: Not yet recruiting

Condition Summary: Brain Neoplasms; Brain Cancer; Brain Tumors; Cancer of the Brain; Cancer of Brain

 

Last Updated: 6 Jan 2015

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Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
 

Status: Recruiting

Condition Summary: Glioma; Brain Cancer; Brain Tumor; Glioblastoma Multiforme; High Grade Glioma

 

Last Updated: 18 Nov 2014

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