Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 683 free, full-text research articles on human participants. First 3 results:

Selection of a Relevant In Vitro Blood-Brain Barrier Model to Investigate Pro-Metastatic Features of Human Breast Cancer Cell Lines.
 

Author(s): Aurore Drolez, Elodie Vandenhaute, Sylvain Julien, Fabien Gosselet, Joy Burchell, Roméo Cecchelli, Philippe Delannoy, Marie-Pierre Dehouck, Caroline Mysiorek

Journal:

 

Around 7-17% of metastatic breast cancer patients will develop brain metastases, associated with a poor prognosis. To reach the brain parenchyma, cancer cells need to cross the highly restrictive endothelium of the Blood-Brain Barrier (BBB). As treatments for brain metastases are ...

Last Updated: 10 Mar 2016

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Antacid Use and De Novo Brain Metastases in Patients with Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer Who Were Treated Using First-Line First-Generation Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors.
 

Author(s): Yu-Mu Chen, Chien-Hao Lai, Huang-Chih Chang, Tung-Ying Chao, Chia-Cheng Tseng, Wen-Feng Fang, Chin-Chou Wang, Yu-Hsiu Chung, Yi-Hsi Wang, Mao-Chang Su, Shih-Feng Liu, Kuo-Tung Huang, Hung-Chen Chen, Ya-Chun Chang, Meng-Chih Lin

Journal:

 

Antacid treatments decrease the serum concentrations of first-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs), although it is unknown whether antacids affect clinical outcomes. As cerebrospinal fluid concentrations of TKIs are much lower than serum ...

Last Updated: 20 Feb 2016

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Exploring the Support Needs of Family Caregivers of Patients with Brain Cancer Using the CSNAT: A Comparative Study with Other Cancer Groups.
 

Author(s): Samar M Aoun, Kathleen Deas, Denise Howting, Gabriel Lee

Journal:

 

A substantial burden is placed on family caregivers of patients diagnosed with brain cancers. Despite this, the support needs of the caregivers are often under-recognised and not addressed adequately in current routine and patient centred clinical care. The Carer Support Needs Assessment ...

Last Updated: 18 Dec 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 91 free, full-text review articles on human participants. First 3 results:

Promising approaches to circumvent the blood-brain barrier: progress, pitfalls and clinical prospects in brain cancer.
 

Author(s): Iason T Papademetriou, Tyrone Porter

Journal: Ther Deliv. 2015 ;6(8):989-1016.

 

Brain drug delivery is a major challenge for therapy of central nervous system (CNS) diseases. Biochemical modifications of drugs or drug nanocarriers, methods of local delivery, and blood-brain barrier (BBB) disruption with focused ultrasound and microbubbles are promising approaches ...

Last Updated: 22 Oct 2015

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Factors Predictive of Improved Survival in Patients With Brain Metastases From Gynecologic Cancer: A Single Institution Retrospective Study of 47 Cases and Review of the Literature.
 

Author(s): Gregory M Gressel, Lisbet S Lundsberg, Gary Altwerger, Tasleem Katchi, Masoud Azodi, Peter E Schwartz, Elena S Ratner, Shari Damast

Journal: Int. J. Gynecol. Cancer. 2015 Nov;25(9):1711-6.

 

The reported incidence of brain metastasis from epithelial ovarian cancer (EOC), endometrial cancer (EC), and cervical cancer (CC) is exceedingly rare. As the long-term survival for patients with gynecologic cancer increases, there has been a corresponding increase in the number of ...

Last Updated: 27 Oct 2015

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Anaplastic lymphoma kinase inhibitors in brain metastases from ALK+ non-small cell lung cancer: hitting the target even in the CNS.
 

Author(s): Samuel J Klempner, Sai-Hong Ignatius Ou

Journal: Chin Clin Oncol. 2015 Jun;4(2):20.

 

The paradigm shift occurring in non-small cell lung cancer (NSCLC) is encapsulated by the management of patients harboring oncogenic anaplastic lymphoma kinase (ALK) rearrangements. The unprecedented improvements in patient outcomes resulting from ALK-directed therapy have led to ...

Last Updated: 26 Jun 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
 

Status: Recruiting

Condition Summary: Brain Neoplasms; Brain Cancer; Brain Tumors; Cancer of the Brain; Cancer of Brain; Seizure

 

Last Updated: 23 Aug 2016

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Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
 

Status: Recruiting

Condition Summary: Glioma; Brain Cancer; Brain Tumor; Glioblastoma Multiforme; High Grade Glioma

 

Last Updated: 1 Aug 2016

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Pilot Trial of Dose-Volume Constraints for Reirradiation of Recurrent Brain Tumors
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 2 Aug 2016

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