Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 604 free, full-text research articles on human participants. First 3 results:

[Analysis of Survival Predictors in Patients with Lung Cancer and Brain Metastases].
 

Author(s): Shaohua Cui, Hao Bai, Lili Dong, Yizhuo Zhao, Aiqin Gu, Wei Zhang, Yuqing Lou, Liyan Jiang

Journal: Zhongguo Fei Ai Za Zhi. 2015 Jul;18(7):436-42.

 

The prognosis for patients with lung cancer and brain metastases remains poor, with approximately 6 months of survival, despite active measures after treatment. In this study, we determined and analyzed clinical parameters that affect the survival of patients with lung cancer and ...

Last Updated: 18 Jul 2015

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Prolonged survival after diagnosis of brain metastasis from breast cancer: contributing factors and treatment implications.
 

Author(s): Yayoi Honda, Tomoyuki Aruga, Toshinari Yamashita, Hiromi Miyamoto, Kazumi Horiguchi, Dai Kitagawa, Nami Idera, Risa Goto, Katsumasa Kuroi

Journal: Jpn. J. Clin. Oncol.. 2015 Aug;45(8):713-8.

 

The prognosis of breast cancer-derived brain metastasis is poor, but new drugs and recent therapeutic strategies have helped extend survival in patients. Prediction of therapeutic responses and outcomes is not yet possible, however. In a retrospective study, we examined prognostic ...

Last Updated: 28 Jul 2015

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ACTN4 and the pathways associated with cell motility and adhesion contribute to the process of lung cancer metastasis to the brain.
 

Author(s): Yufei Gao, Guanghu Li, Liankun Sun, Yichun He, Xiaoyan Li, Zhi Sun, Jihan Wang, Yang Jiang, Jingwei Shi

Journal:

 

The aim of this study was to identify critical gene pathways that are associated with lung cancer metastasis to the brain.

Last Updated: 27 Apr 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 83 free, full-text review articles on human participants. First 3 results:

Role of HER2 in brain metastasis of breast cancer: a systematic review and meta-analysis.
 

Author(s): Akbar Hedayatizadeh-Omran, Alireza Rafiei, Reza Alizadeh-Navaei, Mohsen Tehrani, Reza Valadan, Kambiz Moradzadeh, Mohammad Panbechi, Seyed Mehdi Taghavi

Journal: Asian Pac. J. Cancer Prev.. 2015 ;16(4):1431-4.

 

Breast cancer is one of the most common cancers among women worldwide and the HER2 receptor plays an important role in its development and progression. This systematic review aimed to summarize the role of HER2 in brain metastasis in patients with breast cancer.

Last Updated: 6 Mar 2015

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Patients with single brain metastasis from non-small cell lung cancer equally benefit from stereotactic radiosurgery and surgery: a systematic review.
 

Author(s): Hong Qin, Cancan Wang, Yongyuan Jiang, Xiaoli Zhang, Yao Zhang, Zhihua Ruan

Journal:

 

The appropriate treatment of non-small cell lung cancer (NSCLC) with single brain metastasis (SBM) is still controversial. A systematic review was designed to evaluate the effectiveness of neurosurgery and stereotactic radiosurgery (SRS) in patients with SBM from NSCLC.

Last Updated: 12 Jan 2015

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[Advances in treatment of brain metastases from primary non-small cell lung cancer].
 

Author(s): Gen Lin, Haipeng Xu, Cheng Huang

Journal: Zhongguo Fei Ai Za Zhi. 2014 Dec;17(12):877-83.

 

Metastatic tumors involving the brain are an important complication in the overall management of non-small cell lung cancers. Surgery and radiation remain the cornerstones of the therapy, however, the burgeoning knowledge of tumor biology has facilitated the entry of systemically ...

Last Updated: 25 Dec 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery
 

Status: Not yet recruiting

Condition Summary: Benign Neoplasms, Brain; Brain Cancer; Brain Neoplasms, Benign; Brain Neoplasms, Malignant; Brain Tumor, Primary; Brain Tumor, Recurrent; Brain Tumors; Intracranial Neoplasms; Neoplasms, Brain; Neoplasms, Intracranial; Primary Brain Neoplasms; Primary Malignant Brain Neoplasms; Primary Malignant Brain Tumors; Gliomas; Glioblastoma

 

Last Updated: 30 Oct 2015

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1 Week Versus 6 Weeks of Levetiracetam in Surgical Brain Tumor Patients
 

Status: Recruiting

Condition Summary: Brain Neoplasms; Brain Cancer; Brain Tumors; Cancer of the Brain; Cancer of Brain; Seizure

 

Last Updated: 12 Jan 2016

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Dendritic Cell Vaccine Therapy With In Situ Maturation in Pediatric Brain Tumors
 

Status: Recruiting

Condition Summary: Glioma; Brain Cancer; Brain Tumor; Glioblastoma Multiforme; High Grade Glioma

 

Last Updated: 14 Jan 2016

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