Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 664 free, full-text research articles on human participants. First 3 results:

RNA Sequencing Analysis Reveals Interactions between Breast Cancer or Melanoma Cells and the Tissue Microenvironment during Brain Metastasis.
 

Author(s): Ryo Sato, Teppei Nakano, Mari Hosonaga, Oltea Sampetrean, Ritsuko Harigai, Takashi Sasaki, Ikuko Koya, Hideyuki Okano, Jun Kudoh, Hideyuki Saya, Yoshimi Arima

Journal: Biomed Res Int. 2017 ;2017():8032910.

 

Metastasis is the main cause of treatment failure and death in cancer patients. Metastasis of tumor cells to the brain occurs frequently in individuals with breast cancer, non-small cell lung cancer, or melanoma. Despite recent advances in our understanding of the causes and in the ...

Last Updated: 17 Feb 2017

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Effects of epidermal growth factor receptor-tyrosine kinase inhibitors alone on EGFR-mutant non-small cell lung cancer with brain metastasis.
 

Author(s): Qiuyi Zhang, Xuchao Zhang, Honghong Yan, Benyuan Jiang, Chongrui Xu, Jinji Yang, Zhihong Chen, Jian Su, Yi-Long Wu, Qing Zhou

Journal: Thorac Cancer. 2016 Nov;7(6):648-654.

 

Epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) are remarkably effective for treating EGFR-mutant non-small cell lung cancer (NSCLC). However, the individual role of EGFR-TKIs in patients with brain metastasis (BM) arising from EGFR-mutant NSCLC remains unclear.

Last Updated: 18 Oct 2016

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The Impact of the Stage and Tumor Size on Rare Brain Metastasis of Cervical Cancer.
 

Author(s): Fatma Teke, Senem Yaman Tunc, Memik Teke, Yahya Turan, Zuhat Urakci, Bekir Eren, Suleyman Altin, Mustafa Unsal

Journal: Turk Neurosurg. 2016 ;26(6):818-823.

 

To investigate the clinical features, prognostic factors and survival times of cervical cancer patients with brain metastasis.

Last Updated: 10 Aug 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 106 free, full-text review articles on human participants. First 3 results:

Brain MRI Findings in Neurological Complications of Cancer Treatment.
 

Author(s): Astra Cabaj, Monika Bekiesińska-Figatowska, Agnieszka Duczkowska, Marek Duczkowski

Journal: Adv Clin Exp Med. ;25(4):789-97.

 

The amount of people living with cancer is increasing; they live longer and have thus a higher risk of developing neurological complications. Magnetic resonance as a diagnostic procedure of choice in detecting the reasons of neurological/psychiatric symptoms in oncological patients ...

Last Updated: 16 Sep 2016

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[Advances in Bevacizumab Therapy for Non-small Cell Lung Cancer 
with Brain Metastases].
 

Author(s): Liyan Qu, Rui Geng, Xia Song

Journal: Zhongguo Fei Ai Za Zhi. 2016 Aug;19(8):515-8.

 

Brain metastases are frequently encountered in patients with non-small cell lung cancer (NSCLC) and are a significant cause of morbidity and mortality. Antiangiogenesis therapy plays a major role in the management of brain metastases in lung cancer. Bevacizumab have become the novel ...

Last Updated: 26 Aug 2016

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Pemetrexed/cisplatin as first-line chemotherapy for advanced lung cancer with brain metastases: A case report and literature review.
 

Author(s): Guangzhao He, Xiaoguang Xiao, Man Zou, Chengliang Zhang, Shu Xia

Journal: Medicine (Baltimore). 2016 Aug;95(32):e4401.

 

Brain metastases (BMs) are a common and serious complication of non-small cell lung cancer (NSCLC). Whole-brain radiotherapy (WBRT), surgery, and molecular targeted therapy are usually used to treat NSCLC with BM. Chemotherapeutic options for BM are limited by tumor resistance, ineffective ...

Last Updated: 12 Aug 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of Afatinib for Brain Cancer
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 3 Mar 2017

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Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 29 Mar 2016

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Pilot Trial of Dose-Volume Constraints for Reirradiation of Recurrent Brain Tumors
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 15 Dec 2016

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