Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

View Details
National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

View Details
Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

View Details
National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 713 free, full-text research articles on human participants. First 3 results:

Effects of Chinese medicinal herbs on expression of brain-derived Neurotrophic factor (BDNF) and its interaction with human breast cancer MDA-MB-231 cells and endothelial HUVECs.
 

Author(s): Jen-Hwey Chiu, Fang-Pey Chen, Yi-Fang Tsai, Man-Ting Lin, Ling-Ming Tseng, Yi-Ming Shyr

Journal:

 

Our previous study demonstrated that an up-regulation of the Brain-Derived Neurotrophic Factor (BDNF) signaling pathway is involved the mechanism causing the recurrence of triple negative breast cancer. The aim of this study is to investigate the effects of commonly used Chinese medicinal ...

Last Updated: 12 Aug 2017

Go To URL
The small-molecule kinase inhibitor D11 counteracts 17-AAG-mediated up-regulation of HSP70 in brain cancer cells.
 

Author(s): Susanne Schaefer, Tina H Svenstrup, Barbara Guerra

Journal:

 

Many types of cancer express high levels of heat shock proteins (HSPs) that are molecular chaperones regulating protein folding and stability ensuring protection of cells from potentially lethal stress. HSPs in cancer cells promote survival, growth and spreading even in situations ...

Last Updated: 25 May 2017

Go To URL
Genetically engineered rat gliomas: PDGF-driven tumor initiation and progression in tv-a transgenic rats recreate key features of human brain cancer.
 

Author(s): Nina P Connolly, Jesse A Stokum, Craig S Schneider, Tatsuya Ozawa, Su Xu, Rebeca Galisteo, Rudolph J Castellani, Anthony J Kim, J Marc Simard, Jeffrey A Winkles, Eric C Holland, Graeme F Woodworth

Journal:

 

Previously rodent preclinical research in gliomas frequently involved implantation of cell lines such as C6 and 9L into the rat brain. More recently, mouse models have taken over, the genetic manipulability of the mouse allowing the creation of genetically accurate models outweighed ...

Last Updated: 30 Mar 2017

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 116 free, full-text review articles on human participants. First 3 results:

Evidence of elemene injection combined radiotherapy in lung cancer treatment among patients with brain metastases: A systematic review and meta-analysis.
 

Author(s): Xutao Jiang, Tesfaldet Habtemariam Hidru, Zhuo Zhang, Yu Bai, Lingchao Kong, Xiaofeng Li

Journal: Medicine (Baltimore). 2017 May;96(21):e6963.

 

This review evaluates the effectiveness and safety of elemene injection combined radiotherapy in the treatment of lung cancer with brain metastases.

Last Updated: 24 May 2017

Go To URL
A Neuro-oncologist's Perspective on Management of Brain Metastases in Patients with EGFR Mutant Non-small Cell Lung Cancer.
 

Author(s): Tresa McGranahan, Seema Nagpal

Journal: Curr Treat Options Oncol. 2017 Apr;18(4):22.

 

Management of non-small cell lung cancer (NSCLC) with brain metastasis (BrM) has been revolutionized by identification of molecular subsets that have targetable oncogenes. Historically, survival for NSCLC with symptomatic BrM was weeks to months. Now, many patients are surviving years ...

Last Updated: 9 Apr 2017

Go To URL
Breast Cancer Brain Metastases: Clonal Evolution in Clinical Context.
 

Author(s): Jodi M Saunus, Amy E McCart Reed, Zhun Leong Lim, Sunil R Lakhani

Journal:

 

Brain metastases are highly-evolved manifestations of breast cancer arising in a unique microenvironment, giving them exceptional adaptability in the face of new extrinsic pressures. The incidence is rising in line with population ageing, and use of newer therapies that stabilise ...

Last Updated: 18 Jan 2017

Go To URL
 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of Afatinib for Brain Cancer
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 3 Mar 2017

Go to URL
Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 29 Mar 2016

Go to URL
Pilot Trial of Dose-Volume Constraints for Reirradiation of Recurrent Brain Tumors
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 21 Sep 2017

Go to URL