Brain Cancer

Common Name(s)

Brain Cancer

Brain cancer is when cancer cells divide rapidly in the brain tissue. These cells grow to form a tumor that interferes with important brain functions. These tumors can either be malignant or benign. Benign tumors are noncancerous, because they can only grow locally. While malignant tumors are cancerous, because they can spread to other areas. Cancer cells that develop from brain tissue are called primary brain tumors, while tumors that spread from other regions of the body are called metastatic brain tumors. Brain tumors can be further categorized by their increasing growth rate: Grade I Grade II, Grade III, or Grade IV. Some of the most common symptoms include headaches, nausea and vomiting, changes in ability to talk, see, or hear, and problems with walking, balancing, thinking or memory. Brain cancer is diagnosed by MRI, CT scan, and biopsy tests and often treated with surgery, radiation therapy, and chemotherapy.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

Last Updated: 21 Nov 2014

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Brain Cancer" for support, advocacy or research.

Accelerate Brain Cancer Cure

Our Mission: to invest in research aimed at finding the fastest possible route to a cure. We are focused on speeding the pace of research that will lead to new brain tumor therapies and, ultimately, a cure. We take an aggressive, venture funding approach not typically seen in the nonprofit sector. We have an enterprising attitude, we promote scientific collaboration and we're committed to measurable results.

http://www.abc2.org

Last Updated: 7 Jan 2013

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Cancer Hope Network

To provide one-on-one support to people undergoing treatment for cancer and to their families. We provide this support by training individuals who have recovered from cancer and matching them with cancer patients currently undergoing a similar experience. Through this matching process, we strive to instill hope and to make a difference in their fight against cancer.

http://www.CancerHopeNetwork.org

Last Updated: 29 Jul 2015

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National Brain Tumor Society

National Brain Tumor Society is fiercely committed to finding better treatments, and ultimately a cure, for people living with a brain tumor today and anyone who will be diagnosed tomorrow. This means effecting change in the system at all levels. It’s time to build on progress and transform tomorrow, today.

http://braintumor.org/

Last Updated: 21 Nov 2014

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Brain Cancer" returned 791 free, full-text research articles on human participants. First 3 results:

Activity of Eribulin Mesylate in Brain Metastasis from Breast Cancer: A Stone in a Pond?
 

Author(s): Giovanna Catania, Paola Malaguti, Simona Gasparro, Francesco Cognetti, Antonello Vidiri, Alessandra Fabi

Journal: Oncology. 2018 ;94 Suppl 1():29-33.

 

Brain metastases develop in approximately 10-25% of patients with metastatic breast cancer (MBC) and are associated with a very poor prognosis.

Last Updated: 31 Dec 1969

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Treatment rationale and design of the RAMNITA study: A phase II study of the efficacy of docetaxel + ramucirumab for non-small cell lung cancer with brain metastasis.
 

Author(s): Keiko Tanimura, Junji Uchino, Nobuyo Tamiya, Yoshiko Kaneko, Tadaaki Yamada, Kenichi Yoshimura, Koichi Takayama

Journal: Medicine (Baltimore). 2018 Jun;97(23):e11084.

 

We described the treatment rationale and procedure for a phase II study of docetaxel plus ramucirumab for non-small cell lung cancer (NSCLC) patients with brain metastasis (RAMNITA study: University Information Network Clinical Trials Registry identification no. [UMIN]: 000024551). ...

Last Updated: 31 Dec 1969

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Apatinib + CPT-11 + S-1 for treatment of refractory brain metastases in patient with triple-negative breast cancer: Case report and literature review.
 

Author(s): Ting Hu, Cuiwei Liu, Qiuhui Li, Jie Xiong, Yuxi Ma, Gang Wu, Yanxia Zhao

Journal: Medicine (Baltimore). 2018 Apr;97(15):e0349.

 

Brain metastasis (BM) is a rising challenge in forward-looking oncology, as its treatment choices are very limited, especially, after the failure of local treatment schemes.

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Brain Cancer" returned 133 free, full-text review articles on human participants. First 3 results:

Non-small cell lung cancer brain metastases and the immune system: From brain metastases development to treatment.
 

Author(s): Elie El Rassy, Angela Botticella, Joseph Kattan, Cecile Le Péchoux, Benjamin Besse, Lizza Hendriks

Journal: Cancer Treat. Rev.. 2018 Jul;68():69-79.

 

Brain metastases (BM) are diagnosed frequently in non-small cell lung cancer (NSCLC) patients. Despite the high incidence of BM (up to 40% in unselected patients), patients with untreated and/or unstable BM were excluded from pivotal immune checkpoint inhibitors (ICI) NSCLC trials. ...

Last Updated: 31 Dec 1969

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Systemic Treatment Options for Brain Metastases from Non-Small-Cell Lung Cancer.
 

Author(s): Ajaz Bulbul, Patrick M Forde, Ayesha Murtuza, Brian Woodward, Hannah Yang, Ingmar Bastian, Parissa K Ferguson, Fernando Lopez-Diaz, David S Ettinger, Hatim Husain

Journal: Oncology (Williston Park, N.Y.). 2018 04;32(4):156-63.

 

Brain metastases are common in patients with non-small-cell lung cancer (NSCLC). Because of associated poor prognosis and limited specific treatment options, there is a real need for the development of medical therapies and strategies for affected patients. Novel compounds for epidermal ...

Last Updated: 31 Dec 1969

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The Molecular Mechanisms of Plant-Derived Compounds Targeting Brain Cancer.
 

Author(s): Hueng-Chuen Fan, Ching-Shiang Chi, Yu-Kang Chang, Min-Che Tung, Shinn-Zong Lin, Horng-Jyh Harn

Journal:

 

Glioblastoma multiforme (GBM) is one of the most aggressive and malignant forms of brain tumors. Despite recent advances in operative and postoperative treatments, it is almost impossible to perform complete resection of these tumors owing to their invasive and diffuse nature. Several ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Safety Study of Afatinib for Brain Cancer
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 19 Oct 2017

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Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 23 Jul 2018

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Pilot Trial of Dose-Volume Constraints for Reirradiation of Recurrent Brain Tumors
 

Status: Recruiting

Condition Summary: Brain Cancer

 

Last Updated: 4 May 2018

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