Raynaud's Disease

Common Name(s)

Raynaud's Disease

Raynaud’s disease is a disorder of the blood vessels, in which the blood vessels of the hands, feet, nose, or ears narrow and constrict in response to the cold or stress. When this occurs, blood cannot get to the surface of the skin and the affected areas turn white or blue. Women, those with a family history, and people who live in colder climates are more likely to develop Raynaud’s. Symptoms include cold fingers and toes, prickly or stinging pain upon warming or relief of stress, and a sequence of color changes in skin in response to the cold or stress.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Raynaud's Disease" for support, advocacy or research.

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Raynaud's & Scleroderma Ireland

• To improve the lives of patients, their families and carers by providing support, advice and information. • To increase the awareness of Raynaud’s and Scleroderma amongst healthcare professionals, Government and Statutory agencies and the general public. • To work in partnership with appropriate healthcare professionals and agencies to promote and co-ordinate the attainment of the objectives of the strategy. • Maintain a working environment that fosters communication, teamwork and diversity among all members of staff- permanent, temporary and voluntary

Last Updated: 6 May 2014

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Raynaud's Association

The Raynaud's Association was founded to help Raynaud's sufferers cope with day-to-day activities for maintaining or improving their quality of life. The organization is committed to: (1) Member Support Services - offering sharing, support, and education to fellow Raynaud's sufferers. (2) Increasing Public Awareness of Raynaud's - so more sufferers recognize the symptoms and seek treatment. (3) Helping the Medical Community Research Treatments and Potential Cures for Raynaud's - through patient recruitment and, eventually, funding for research.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Raynaud's Disease" for support, advocacy or research.

Logo
Raynaud's & Scleroderma Ireland

• To improve the lives of patients, their families and carers by providing support, advice and information. • To increase the awareness of Raynaud’s and Scleroderma amongst healthcare professionals, Government and Statutory agencies and the general public. • To work in partnership with appropriate healthcare professionals and agencies to promote and co-ordinate the attainment of the objectives of the strategy. • Maintain a working environment that fosters communication, teamwork and diversity among all members of staff- permanent, temporary and voluntary

http://www.irishraynauds.com

Last Updated: 6 May 2014

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Raynaud's Association

The Raynaud's Association was founded to help Raynaud's sufferers cope with day-to-day activities for maintaining or improving their quality of life. The organization is committed to: (1) Member Support Services - offering sharing, support, and education to fellow Raynaud's sufferers. (2) Increasing Public Awareness of Raynaud's - so more sufferers recognize the symptoms and seek treatment. (3) Helping the Medical Community Research Treatments and Potential Cures for Raynaud's - through patient recruitment and, eventually, funding for research.

http://www.raynauds.org/

Last Updated: 20 Feb 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Raynaud's Disease" returned 38 free, full-text research articles on human participants. First 3 results:

Cervical spinal cord stimulation with 5-column paddle lead in Raynaud's disease.
 

Author(s): Mohammed A Issa, Chong H Kim

Journal: Pain Physician. ;15(4):303-9.

 

To report a case of Raynaud disease and its successful treatment with spinal cord stimulation utilizing the newly designed five-column Penta lead paddle. Specific electrode design, programming characteristics, and surgical technique are also discussed in this case.

Last Updated: 25 Jul 2012

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[Nailfold capillaroscopy in the evaluation of Raynaud's phenomenon and undifferentiated connective tissue disease].
 

Author(s): Sara Cortes, Paulo Clemente-Coelho

Journal: Acta Reumatol Port. ;33(2):203-9.

 

Microvascular abnormalities involved in the pathogenic mechanism of several connective tissue disorders can be detected by nailfold capillaroscopy.

Last Updated: 7 Jul 2008

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Comment on: a case of Raynaud's phenomenon in mixed connective tissue disease responding to Rituximab therapy response.
 

Author(s): L Dunkley, M Green, A Gough

Journal: Rheumatology (Oxford). 2007 Oct;46(10):1628-9.

 

Last Updated: 24 Sep 2007

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Raynaud's Disease" returned 4 free, full-text review articles on human participants. First 3 results:

Quantifying digital vascular disease in patients with primary Raynaud's phenomenon and systemic sclerosis.
 

Author(s): A L Herrick, S Clark

Journal: Ann. Rheum. Dis.. 1998 Feb;57(2):70-8.

 

Last Updated: 11 Jun 1998

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Endothelin and collagen vascular disease: a review with special reference to Raynaud's phenomenon and systemic sclerosis.
 

Author(s): K Yamane

Journal: Intern. Med.. 1994 Oct;33(10):579-82.

 

Endothelin-1 (ET-1), endothelin-2, and endothelin-3, a family of 21-aminoacid peptides, are potent, long-acting vasoconstrictors of mammalian blood vessels. Elevated levels of ET-1 have been found in the circulation of patients with various diseases, all of which have some degree ...

Last Updated: 22 Feb 1995

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[Angiosarcoma, Raynaud's disease and arteriovenous malformation of the digestive tract. A causal relationship or a chance association?].
 

Author(s): F Vaz, J T de Castro, V Tomé, J M Marques, V de Carvalho

Journal: Acta Med Port. 1994 Feb;7(2):107-11.

 

A case of angiosarcoma, Raynaud's disease and arteriovenous malformation of the intestinal tract is presented. We propose the association of these three vascular diseases, which has not yet been described. The study of more cases is important in order to understand the physiopathological ...

Last Updated: 8 Jun 1994

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Jul 2014

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Laser Speckle Contrast Imaging for Cutaneous Microvascular Dysfunction Detection in Systemic Sclerosis.
 

Status: Recruiting

Condition Summary: Raynaud Disease; Scleroderma, Systemic

 

Last Updated: 17 Jul 2013

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Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis
 

Status: Recruiting

Condition Summary: Primary Raynaud Disease; Systemic Sclerosis

 

Last Updated: 6 Aug 2014

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