Vasculitis

Common Name(s)

Vasculitis

Vasculitis is redness and swelling (inflammation) of the system of small tubes that carry blood throughout your body (vessels, arteries, veins and capillaries). This inflammation can cause these tubes to become weak and narrow, leading to a blockage which will cut off blood supply to an area of the body. Vasculitis can affect any area of the body, leading to damage of any organ or tissue.

The symptoms of vasculitis vary depending on which organ or tissue is affected. Symptoms may include a rash, muscle weakness, fever, weight loss, general fatigue, kidney failure, heart attack or stroke. Vasculitis can be diagnosed by your doctor using a combination of your health history, physical exam, blood and urine tests to look for signs of inflammation or organ damage, imaging tests (x-ray, CT or MRI) to look for inflammation and organ damage, and removal of a small piece of affected tissue (biopsy) to look for signs of vasculitis.

Treatment options depends on which tissue or organ is affected. In some cases, treatment may not be necessary and the inflammation will go away on its own. Other times, medications may be necessary to prevent further damage and relieve symptoms. If you have been diagnosed with vasculitis, talk with your doctor about the most current treatment options. Support groups are a good resource for additional information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

Last Updated: 29 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

http://allianceforcryo.org/

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

http://www.alpha1awareness.org.uk

Last Updated: 29 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vasculitis" returned 1569 free, full-text research articles on human participants. First 3 results:

Fludeoxyglucose positron emission tomography-computed tomography scan showing polyarthritis in a patient with an atypical presentation of Henoch-Schönlein vasculitis without clinical signs of arthritis: a case report.
 

Author(s): Christiaan F Mooij, Rick Hermsen, Esther P A H Hoppenreijs, Chantal P Bleeker-Rovers, Marloes M IJland, Lioe-Fee de Geus-Oei

Journal:

 

Henoch-Schönlein vasculitis is the most common systemic vasculitis in children. Arthritis or arthralgia occurs in 80 % of patients. We believe this to be the first case report to describe the finding of polyarthritis in a fludeoxyglucose positron emission tomography-computed tomography ...

Last Updated: 3 Jun 2016

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CNS vasculitis and stroke as a complication of DOCK8 deficiency: a case report.
 

Author(s): Suzan A AlKhater

Journal:

 

Primary immunodeficiency disorders associated with autoimmunity are poorly understood. Central nervous system (CNS) vasculitis can complicate the courses of such entities, but it is underappreciated. Deletion of the dedicator of cytokinesis 8 (DOCK8) gene is considered to be the autosomal ...

Last Updated: 26 Apr 2016

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Long-term Prognosis of Anti-Neutrophil Cytoplasmic Antibody-Negative Renal Vasculitis: Cohort Study in Korea.
 

Author(s): Sung Woo Lee, Mi-Yeon Yu, Seon Ha Baek, Shin-Young Ahn, Sejoong Kim, Ki Young Na, Dong-Wan Chae, Ho Jun Chin

Journal: J. Korean Med. Sci.. 2016 Apr;31(4):542-6.

 

Few studies have reported on the long-term prognosis of anti-neutrophil cytoplasmic antibody (ANCA)-negative renal vasculitis. Between April 2003 and December 2013, 48 patients were diagnosed with renal vasculitis. Their ANCA status was tested using indirect immunofluorescence and ...

Last Updated: 7 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vasculitis" returned 270 free, full-text review articles on human participants. First 3 results:

One year in review: systemic vasculitis.
 

Author(s): Elena Elefante, Alessandra Tripoli, Francesco Ferro, Chiara Baldini

Journal: Clin. Exp. Rheumatol.. ;34(3 Suppl 97):S1-6.

 

Systemic vasculitis are complex and heterogenous disorders. During the past months great efforts have been made aimed at clarifying disease pathogenesis and at improving patient management and treatment. In this review we summarise the most important scientific contributions on vasculitis ...

Last Updated: 31 May 2016

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Rare type of pancreatitis as the first presentation of anti-neutrophil cytoplasmic antibody-related vasculitis.
 

Author(s): Tomoya Iida, Takeya Adachi, Tetsuya Tabeya, Suguru Nakagaki, Takashi Yabana, Akira Goto, Yoshihiro Kondo, Kiyoshi Kasai

Journal: World J. Gastroenterol.. 2016 Feb;22(7):2383-90.

 

A pancreatic tumor was suspected on the abdominal ultrasound of a 72-year-old man. Abdominal computed tomography showed pancreatic enlargement as well as a diffuse, poorly enhanced area in the pancreas; endoscopic ultrasound-guided fine needle aspiration biopsy and endoscopic retrograde ...

Last Updated: 22 Feb 2016

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Pauci-Immune Crescentic Glomerulonephritis: An ANCA-Associated Vasculitis.
 

Author(s): Rafeel Syed, Amina Rehman, Gautam Valecha, Suzanne El-Sayegh

Journal: Biomed Res Int. 2015 ;2015():402826.

 

Rapidly progressive glomerulonephritis (RPGN) is a syndrome signified by a precipitous loss of renal function, with features of glomerulonephritis including dysmorphic erythrocyturia and glomerular proteinuria. RPGN is associated with extensive crescent formation, and, thus, the clinical ...

Last Updated: 21 Dec 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Endothelin Antagonism in ANCA Vasculitis
 

Status: Recruiting

Condition Summary: Vasculitis

 

Last Updated: 29 Aug 2016

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Optical Coherence Tomography (OCT) in Retinal Vasculitis
 

Status: Recruiting

Condition Summary: Retinal Vasculitis

 

Last Updated: 21 Apr 2015

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A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis
 

Status: Recruiting

Condition Summary: ANCA-Associated Vasculitis

 

Last Updated: 16 Jan 2017

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