Vasculitis

Common Name(s)

Vasculitis

Vasculitis is an inflammation of the vascular system, which includes the veins, arteries, and capillaries. There are many different forms of vasculitis, including temporal arteritis, primary angiitis of the central nervous system, Takayasu disease, periarteritis nodosa, Kawasaki disease, Churg-Strauss syndrome, Wegener granulomatosis, systemic lupus erythematosus, scleroderma, rheumatoid arthritis, Sjogren syndrome, Behcet disease and others. Signs and symptoms of vasculitis vary depending on the form and on the part of the body affected. In general, the cause of vasculitis is thought to be a faulty immune system response. Treatment of vasculitis depends upon the specific diagnosis. Most of forms of vasculitis respond well to steroid drugs. Some may also require treatment with an immunosuppressive drug, such as cyclophosphamide.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

Last Updated: 29 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

http://allianceforcryo.org/

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

http://www.alpha1awareness.org.uk

Last Updated: 29 Mar 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vasculitis" returned 1207 free, full-text research articles on human participants. First 3 results:

Rituximab or azathioprine maintenance in ANCA-associated vasculitis.
 

Author(s): Christian Pagnoux, Loïc Guillevin, ,

Journal: N. Engl. J. Med.. 2015 Jan;372(4):386-7.

 

Last Updated: 22 Jan 2015

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Resolution of urticarial vasculitis after treatment of neurocysticercosis.
 

Author(s): Sheila Shaigany, Ellen Dabela, Andrew F Teich, Sameera Husain, Marc E Grossman

Journal: J. Am. Acad. Dermatol.. 2015 Jan;72(1):e32-3.

 

Last Updated: 16 Dec 2014

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Membranoproliferative glomerulonephritis presenting as arthropathy and cardiac valvulopathy in hypocomplementemic urticarial vasculitis: a case report.
 

Author(s): Chuiyoung Park, Seung Won Choi, Misung Kim, Jongha Park, Jong Soo Lee, Hyun Chul Chung

Journal:

 

Hypocomplementemic urticarial vasculitis syndrome is a rare disorder characterized by chronic urticarial vasculitis, arthralgia, arthritis, and hypocomplementemia. Previously, only six patients with concomitant hypocomplementemic urticarial vasculitis syndrome, Jaccoud's arthropathy, ...

Last Updated: 28 Oct 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vasculitis" returned 220 free, full-text review articles on human participants. First 3 results:

The immunopathology of ANCA-associated vasculitis.
 

Author(s): Eoin F McKinney, Lisa C Willcocks, Verena Broecker, Kenneth G C Smith

Journal: Semin Immunopathol. 2014 Jul;36(4):461-78.

 

The small-vessel vasculitides are a group of disorders characterised by variable patterns of small blood vessel inflammation producing a markedly heterogeneous clinical phenotype. While any vessel in any organ may be involved, distinct but often overlapping sets of clinical features ...

Last Updated: 1 Aug 2014

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Myocarditis, pancreatitis, polyarthritis, mononeuritis multiplex and vasculitis with symmetrical peripheral gangrene of the lower extremities as a rare presentation of leptospirosis: a case report and review of the literature.
 

Author(s): Periklis Panagopoulos, Irene Terzi, Michail Karanikas, Nikolaos Galanopoulos, Efstratios Maltezos

Journal:

 

Leptospirosis is a zoonosis caused by the spirochete, Leptospira interrogans. While most cases of leptospirosis are mild to moderate, the course may be complicated by multiorgan dysfunction. We present a rare case of leptospirosis with acute myocarditis, pancreatitis, polyarthritis, ...

Last Updated: 4 Jun 2014

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Anti-TNF-alpha therapy and systemic vasculitis.
 

Author(s): Pierre-André Jarrot, Gilles Kaplanski

Journal: Mediators Inflamm.. 2014 ;2014():493593.

 

TNF-α is a pleiotropic cytokine, which plays a major role in the pathogenesis of numerous autoimmune and/or inflammatory systemic diseases. Systemic vasculitis constitutes a group of rare diseases, characterized by inflammation of the arterial or venous vessel wall, causing stenosis ...

Last Updated: 10 Apr 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pediatric Vasculitis Initiative
 

Status: Recruiting

Condition Summary: Wegeners Granulomatosis (Granulomatosis With Polyangiitis); Microscopic Polyangiitis; Churg Strauss Syndrome (Eosinophilic Granulomatosis With Polyangiitis); Polyarteritis Nodosa; Takayasu Arteritis; Primary CNS Vasculitis; Unclassified Vasculitis

 

Last Updated: 2 Dec 2014

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Alemtuzumab for ANCA Associated Refractory Vasculitis
 

Status: Recruiting

Condition Summary: Vasculitis; Microscopic Polyangiitis; Granulomatosis With Polyangiitis; Wegener's

 

Last Updated: 28 Jul 2011

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Clinical Trial to Evaluate Safety and Efficacy of CCX168 in ANCA-Associated Vasculitis
 

Status: Recruiting

Condition Summary: ANCA-associated Vasculitis

 

Last Updated: 20 Mar 2015

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