Vasculitis

Common Name(s)

Vasculitis

Vasculitis is redness and swelling (inflammation) of the system of small tubes that carry blood throughout your body (vessels, arteries, veins and capillaries). This inflammation can cause these tubes to become weak and narrow, leading to a blockage which will cut off blood supply to an area of the body. Vasculitis can affect any area of the body, leading to damage of any organ or tissue.

The symptoms of vasculitis vary depending on which organ or tissue is affected. Symptoms may include a rash, muscle weakness, fever, weight loss, general fatigue, kidney failure, heart attack or stroke. Vasculitis can be diagnosed by your doctor using a combination of your health history, physical exam, blood and urine tests to look for signs of inflammation or organ damage, imaging tests (x-ray, CT or MRI) to look for inflammation and organ damage, and removal of a small piece of affected tissue (biopsy) to look for signs of vasculitis.

Treatment options depends on which tissue or organ is affected. In some cases, treatment may not be necessary and the inflammation will go away on its own. Other times, medications may be necessary to prevent further damage and relieve symptoms. If you have been diagnosed with vasculitis, talk with your doctor about the most current treatment options. Support groups are a good resource for additional information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

Last Updated: 29 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

http://allianceforcryo.org/

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

http://www.alpha1awareness.org.uk

Last Updated: 29 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vasculitis" returned 1394 free, full-text research articles on human participants. First 3 results:

[Systemic necrotizing vasculitis presenting as gangrene combined with diabetes insipidus: a case report].
 

Author(s): Qing Huang, Yu-lan Liu

Journal: Beijing Da Xue Xue Bao. 2015 Dec;47(6):1028-30.

 

The male patient reported here presented as gangrene and central diabetes insipidus (CDI), who had characteristics of vasculitis. The patient complained about polydipsia and polyuria half a year ago, and then developed tingling, pain and blackish discoloration of some fingers and ...

Last Updated: 18 Dec 2015

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Ileo-Ileal Intussusception caused by an Inverted Meckel's Diverticulum Eliciting a Systemic Vasculitis-Like Response.
 

Author(s): Avinoam Nevler, Sagi Arieh Shpitzer, Daniel Shinhar, Ron Bilik

Journal: Isr. Med. Assoc. J.. 2015 Oct;17(10):646-7.

 

Last Updated: 10 Dec 2015

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Drug-induced lupus with leukocytoclastic vasculitis: a rare expression associated with adalimumab.
 

Author(s): Carolina Forte Amarante, Livia Mendes Sabia Acedo, Fátima Maria de Oliveira Rabay, Benedito do Espírito Santo Campos, Márcia Lanzoni de Alvarenga Lira, Samuel Henrique Mandelbaum

Journal: An Bras Dermatol. ;90(3 Suppl 1):121-4.

 

TNF alpha antagonist-induced lupus-like syndrome is a rare condition which predominantly affects women (4:1). The average age of onset is 46-51 years. It occurs after exposure to TNF alpha antagonist and disappears after discontinuation of such agents. The pathogenic mechanism for ...

Last Updated: 28 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vasculitis" returned 248 free, full-text review articles on human participants. First 3 results:

[Renal damage caused by Rhupus syndrome associated with anti-neutrophil cytoplasmic antibodies vasculitis and cryoglobulinemia].
 

Author(s): Xin-ju Zhao, Tao Wei, Bao Dong, Yuan Jia, Mei Wang

Journal: Beijing Da Xue Xue Bao. 2015 Oct;47(5):870-4.

 

We analyzed the clinicopathological characteristics of one patient with Rhupus syndrome associated nephropathy in Peking University People's Hospital, and reviewed the related literature. The patient was a middle aged female. She developed rheumatoid arthritis first, and then manifested ...

Last Updated: 17 Oct 2015

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Concurrent pulmonary hemorrhage and deep vein thrombosis in a child with ANCA-associated vasculitis: case report and review of literature.
 

Author(s): Shi-Ting Tseng, Min-Hua Tseng, Jing-Long Huang

Journal:

 

Antineutrophil cytoplasmic antibody-associated vasculitis (AAV) is an uncommon but potentially life threatening disease in children. Pulmonary hemorrhage (PH) is a well recognized but lethal complication. The incidence of venous thromboembolism (VTE) is higher in patients with AAV, ...

Last Updated: 10 Jun 2015

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Management of large-vessel vasculitis with FDG-PET: a systematic literature review and meta-analysis.
 

Author(s): Michael Soussan, Patrick Nicolas, Catherine Schramm, Sandrine Katsahian, Gabriel Pop, Olivier Fain, Arsene Mekinian

Journal: Medicine (Baltimore). 2015 Apr;94(14):e622.

 

We aimed to clarify the role of 18F-fluorodeoxyglucose positron emission tomography (FDG-PET) in the management of large-vessel vasculitis (LVV), focusing on 3 issues which are as follows: describe and determine the different FDG-PET criteria for the diagnosis of vascular inflammation, ...

Last Updated: 11 Apr 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Vasculitis Pregnancy Registry
 

Status: Recruiting

Condition Summary: Vasculitis; Behcet's Disease; CNS Vasculitis; Cryoglobulinemic Vasculitis; Eosinophilic Granulomatosis With Polyangiitis (EGPA); Churg-Strauss Syndrome (CSS); Granulomatosis With Polyangiitis (GPA); Wegener's Granulomatosis; IgA Vasculitis; Henoch-Schoenlein Purpura (HSP); Microscopic Polyangiitis (MPA); Polyarteritis Nodosa (PAN); Takayasu Arteritis (TAK); Urticarial Vasculitis; Systemic Vasculitis

 

Last Updated: 14 Jan 2016

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Pediatric Vasculitis Initiative
 

Status: Recruiting

Condition Summary: Wegeners Granulomatosis (Granulomatosis With Polyangiitis); Microscopic Polyangiitis; Churg Strauss Syndrome (Eosinophilic Granulomatosis With Polyangiitis); Polyarteritis Nodosa; Takayasu Arteritis; Primary CNS Vasculitis; Unclassified Vasculitis

 

Last Updated: 16 Jul 2015

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Alemtuzumab for ANCA Associated Refractory Vasculitis
 

Status: Recruiting

Condition Summary: Vasculitis; Microscopic Polyangiitis; Granulomatosis With Polyangiitis; Wegener's

 

Last Updated: 28 Jul 2011

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