Vasculitis

Common Name(s)

Vasculitis

Vasculitis is redness and swelling (inflammation) of the system of small tubes that carry blood throughout your body (vessels, arteries, veins and capillaries). This inflammation can cause these tubes to become weak and narrow, leading to a blockage which will cut off blood supply to an area of the body. Vasculitis can affect any area of the body, leading to damage of any organ or tissue.

The symptoms of vasculitis vary depending on which organ or tissue is affected. Symptoms may include a rash, muscle weakness, fever, weight loss, general fatigue, kidney failure, heart attack or stroke. Vasculitis can be diagnosed by your doctor using a combination of your health history, physical exam, blood and urine tests to look for signs of inflammation or organ damage, imaging tests (x-ray, CT or MRI) to look for inflammation and organ damage, and removal of a small piece of affected tissue (biopsy) to look for signs of vasculitis.

Treatment options depends on which tissue or organ is affected. In some cases, treatment may not be necessary and the inflammation will go away on its own. Other times, medications may be necessary to prevent further damage and relieve symptoms. If you have been diagnosed with vasculitis, talk with your doctor about the most current treatment options. Support groups are a good resource for additional information.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

Last Updated: 29 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Vasculitis" for support, advocacy or research.

Alliance for Cryoglobulinemia

Alliance for Cryoglobulinemia is an inclusive network of patients, caregivers, family, medical professionals and other supporters dedicated to improving quality of life for people with cryoglobulinemia. Our goal is to create a platform that links all efforts of campaigns, research, support and other resources related to cryoglobulinemia. We utilize medical advisors, community networking, crowd-funding, peer to peer support, social media and campaign strategies to advocate awareness, patient support, education and research.

http://allianceforcryo.org/

Last Updated: 24 Apr 2015

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Alpha-1 Awareness UK

Alpha-1 Awareness UK is a charity formed to provide information and support to sufferers of alpha-1 antitrypsin deficiency. We maintain close links with experts and organisations associated with the condition, including European Alpha groups, pharmaceuticals and clinicians. Our primary objective is to improve the understanding of A1AT in both patients and medical professionals, as well as to provide support for Alphas and their carers.

http://www.alpha1awareness.org.uk

Last Updated: 29 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Vasculitis" returned 1247 free, full-text research articles on human participants. First 3 results:

[Benzylthiouracil induced ANCA-positive vasculitis].
 

Author(s): Lilia Baili, Zohra Aydi, Fatma Daoud, Besma Ben Dhaou, Ezzedine Boussema, Samir Kochbati, Fatma Boussema

Journal: Tunis Med. 2014 Jun;92(6):428-30.

 

Last Updated: 6 Mar 2015

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[Non small-cell lung cancer revealed by retinal vasculitis].
 

Author(s): Besma Ben Dhaou, Zohra Aydi, Sonia Seghaier, Lilia Baili, Fatma Boussema, Mohamed Habib Daghfous, Lilia Rokbani

Journal: Tunis Med. 2014 Jun;92(6):423-5.

 

Last Updated: 6 Mar 2015

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[Septic vasculitis caused by Listeria monocytogenes].
 

Author(s): Cristián Vera-Kellet, Constanza Del Puerto, Felipe Ruiz, Sergio González, Jorge Manríquez

Journal: Rev Chilena Infectol. 2014 Dec;31(6):746-9.

 

Septic vasculitis is a medium and small-vessel vasculitis caused by direct action of pathogens, associated with bacteremia. It is an uncommon condition; clinical manifestations include purpura, ulcers and vesicles-pustules. Most cases of septic vasculitis are related to meningococcemia. ...

Last Updated: 14 Feb 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Vasculitis" returned 234 free, full-text review articles on human participants. First 3 results:

Limitations of standard immunosuppressive treatment in ANCA-associated vasculitis and lupus nephritis.
 

Author(s): Vladimir Tesar, Zdenka Hruskova

Journal: Nephron Clin Pract. 2014 ;128(3-4):205-15.

 

Introduction of the standard immunosuppressive treatment has dramatically changed the outcome of patients with both ANCA-associated vasculitis and lupus nephritis, transforming them from incurable diseases with very high short-term mortality to chronic debilitating diseases with much ...

Last Updated: 9 Feb 2015

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Rituximab in the treatment of anti-neutrophil cytoplasm antibody-associated vasculitis.
 

Author(s): Rachel B Jones

Journal: Nephron Clin Pract. 2014 ;128(3-4):243-9.

 

The introduction of cyclophosphamide and high-dose glucocorticoids for anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis (AAV) has allowed a reduction in 1-year mortality from 80% to 10-20%. AAV is now a chronic disease, and greater emphasis has turned to improving treatment-related ...

Last Updated: 9 Feb 2015

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Pathogenesis of antineutrophil cytoplasmic autoantibody-associated vasculitis and potential targets for biologic treatment.
 

Author(s): J S F Sanders, W H Abdulahad, C A Stegeman, C G M Kallenberg

Journal: Nephron Clin Pract. 2014 ;128(3-4):216-23.

 

Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV) are autoimmune diseases in which the small vessels are inflamed. Clinical observations suggest a pathogenic role for ANCA. Such a role is supported by in vitro experimental data and animal models, particularly ...

Last Updated: 9 Feb 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Pediatric Vasculitis Initiative
 

Status: Recruiting

Condition Summary: Wegeners Granulomatosis (Granulomatosis With Polyangiitis); Microscopic Polyangiitis; Churg Strauss Syndrome (Eosinophilic Granulomatosis With Polyangiitis); Polyarteritis Nodosa; Takayasu Arteritis; Primary CNS Vasculitis; Unclassified Vasculitis

 

Last Updated: 16 Jul 2015

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Impact of Vasculitis on Employment and Income
 

Status: Recruiting

Condition Summary: Vasculitis; Systemic Vasculitis; Behcet's Disease; CNS Vasculitis; Cryoglobulinemic Vasculitis; Eosinophilic Granulomatosis; Temporal Arteritis; Wegener Granulomatosis; Henoch-Schoenlein Purpura; Microscopic Polyangiitis; Polyarteritis Nodosa (PAN); Takayasu's Arteritis; Urticarial Vasculitis

 

Last Updated: 18 Jun 2015

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Alemtuzumab for ANCA Associated Refractory Vasculitis
 

Status: Recruiting

Condition Summary: Vasculitis; Microscopic Polyangiitis; Granulomatosis With Polyangiitis; Wegener's

 

Last Updated: 28 Jul 2011

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