Moyamoya disease

Common Name(s)

Moyamoya disease

Moyamoya disease is a rare, progressive, blood vessel disease caused by blocked arteries at the base of the brain in an area called the basal ganglia. The name "moyamoya" means "puff of smoke" in Japanese and describes the look of the tangled vessels that form to compensate for the blockage. This condition usually affects children, but can affect adults. Affected people are at increased risk for blood clots, strokes, and transient ischemic attacks (TIAs) which are frequently accompanied by seizures and muscular weakness, or paralysis on one side of the body. Affected people may also have disturbed consciousness, speech deficits (usually aphasia), sensory and cognitive impairments, involuntary movements, and vision problems. Researchers believe that Moyamoya disease is an inherited condition because it tends to run in families.

Moyamoya syndrome is a related term that refers to cases of moyamoya disease that occur in association with other conditions or risk factors, such as neurofibromatosis, tuberculosis meningitis, sickle cell disease, leptospirosis, brain tumors, Sturge-Weber syndrome, and tuberous sclerosis.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Moyamoya disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Moyamoya disease" returned 395 free, full-text research articles on human participants. First 3 results:

ANCA positive relapsing polychondritis, Graves disease, and suspected moyamoya disease: A case report.
 

Author(s): Yi-Yi Xuan, Tian-Fang Li, Lei Zhang, Sheng-Yun Liu

Journal: Medicine (Baltimore). 2017 Dec;96(51):e9378.

 

Relapsing polychondritis (RP) is a rare and heterogeneous disease complex of unknown origin which basically affects cartilaginous structures, 40% of which accompanied by rheumatic, hematologic, and endocrine disease. Among them, vasculitis is the most common accompanying type and ...

Last Updated: 31 Dec 1969

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Magnetic resonance angiography with compressed sensing: An evaluation of moyamoya disease.
 

Author(s): Takayuki Yamamoto, Tomohisa Okada, Yasutaka Fushimi, Akira Yamamoto, Koji Fujimoto, Sachi Okuchi, Hikaru Fukutomi, Jun C Takahashi, Takeshi Funaki, Susumu Miyamoto, Aurélien F Stalder, Yutaka Natsuaki, Peter Speier, Kaori Togashi

Journal:

 

Compressed sensing (CS) reconstructions of under-sampled measurements generate missing data based on assumptions of image sparsity. Non-contrast time-of-flight MR angiography (TOF-MRA) is a good candidate for CS based acceleration, as MRA images feature bright trees of sparse vessels ...

Last Updated: 31 Dec 1969

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Color Doppler ultrasonography as an alternative tool for postoperative evaluation of collaterals after indirect revascularization surgery in Moyamoya disease.
 

Author(s): Shin-Joe Yeh, Sung-Chun Tang, Li-Kai Tsai, Chung-Wei Lee, Ya-Fang Chen, Hon-Man Liu, Shih-Hung Yang, Meng-Fai Kuo, Jiann-Shing Jeng

Journal:

 

The cerebral hypoperfusion caused by chronic progressive stenosis or occlusion of intracranial arteries in moyamoya disease can be treated by direct bypass or indirect revascularization procedures. The extent of collaterals from the external carotid artery (ECA) after indirect revascularization ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Moyamoya disease" returned 37 free, full-text review articles on human participants. First 3 results:

Rare variants of RNF213 and moyamoya/non-moyamoya intracranial artery stenosis/occlusion disease risk: a meta-analysis and systematic review.
 

Author(s): Xin Liao, Jing Deng, Wenjie Dai, Tong Zhang, Junxia Yan

Journal:

 

The p.R4810K and other rare variants of ring finger protein 213 gene (RNF213) were illustrated as susceptibility variants for moyamoya (MMD) and non-moyamoya intracranial artery stenosis/occlusion disease (ICASO) recently. However, the effect sizes of p.R4810K were in great discrepancy ...

Last Updated: 31 Dec 1969

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Role of Ring Finger Protein 213 in Moyamoya Disease.
 

Author(s): Yong-Gang Ma, Qian Zhang, Le-Bao Yu, Ji-Zong Zhao

Journal: Chin. Med. J.. 2016 10;129(20):2497-2501.

 

The aim of this study was to help people comprehensively understand the research advances related to ring finger protein 213 (RNF213) in moyamoya disease (MMD) and to understand the disease at the molecular level to provide a new perspective of the diagnosis of the disease.

Last Updated: 31 Dec 1969

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Moyamoya Disease: A Review of Clinical Research.
 

Author(s): Tomohito Hishikawa, Kenji Sugiu, Isao Date

Journal: Acta Med. Okayama. 2016 Aug;70(4):229-36.

 

About 5 decades have passed since the concept of moyamoya disease (MMD) was established in Japan. In that time, many clinical MMD studies have been performed from several different points of view, such as epidemiology, pathophysiology, surgical procedures, and prognosis. In addition, ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Precision Bypass in Patients With Moyamoya Disease
 

Status: Recruiting

Condition Summary: Moyamoya Disease

 

Last Updated: 2 May 2018

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Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease
 

Status: Recruiting

Condition Summary: Moyamoya Disease

 

Last Updated: 2 Dec 2016

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Efficacy and Safety of rTMS for Cognitive Rehabilitation in Moyamoya Disease
 

Status: Not yet recruiting

Condition Summary: Moyamoya Disease

 

Last Updated: 20 May 2018

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