Moyamoya disease

Common Name(s)

Moyamoya disease

Moyamoya disease is a rare, progressive, blood vessel disease caused by blocked arteries at the base of the brain in an area called the basal ganglia. The name "moyamoya" means "puff of smoke" in Japanese and describes the look of the tangled vessels that form to compensate for the blockage. This condition usually affects children, but can affect adults. Affected people are at increased risk for blood clots, strokes, and transient ischemic attacks (TIAs) which are frequently accompanied by seizures and muscular weakness, or paralysis on one side of the body. Affected people may also have disturbed consciousness, speech deficits (usually aphasia), sensory and cognitive impairments, involuntary movements, and vision problems. Researchers believe that Moyamoya disease is an inherited condition because it tends to run in families.

Moyamoya syndrome is a related term that refers to cases of moyamoya disease that occur in association with other conditions or risk factors, such as neurofibromatosis, tuberculosis meningitis, sickle cell disease, leptospirosis, brain tumors, Sturge-Weber syndrome, and tuberous sclerosis.

 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Moyamoya disease" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Moyamoya disease" returned 335 free, full-text research articles on human participants. First 3 results:

The Efficacy of Surgical Treatment for the Secondary Prevention of Stroke in Symptomatic Moyamoya Disease: A Meta-Analysis.
 

Author(s): Cong Qian, Xiaobo Yu, Jianru Li, Jingyin Chen, Lin Wang, Gao Chen

Journal: Medicine (Baltimore). 2015 Dec;94(49):e2218.

 

The treatment of moyamoya disease (MMD) is controversial and often depends on the doctor's experience. In addition, the choice of surgical procedure to treat MMD can differ in many ways. In this study, we performed a meta-analysis to determine whether surgical treatment of MMD is ...

Last Updated: 15 Dec 2015

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Moyamoya Disease Associated with Recurrent Right Thalamic Haemorrhage and Hydrocephalus: A Case Report.
 

Author(s): Rohan Sinha, Amit Kumar Jain, Nitin Jagdhane, Parvati Nandy, Satish Kumar Khanna

Journal: Turk Neurosurg. 2015 ;25(5):811-3.

 

Moyamoya disease, a rare chronic, progressive cerebrovascular disease leads to occlusion of intracranial internal carotid arteries and its proximal branches. We report a case of a 51-year-old female who presented with recurrent thalamic bleed and intraventricular haemorrhage nine ...

Last Updated: 7 Oct 2015

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Ivy Sign on Fluid-Attenuated Inversion Recovery Images in Moyamoya Disease: Correlation with Clinical Severity and Old Brain Lesions.
 

Author(s): Kwon-Duk Seo, Sang Hyun Suh, Yong Bae Kim, Ji Hwa Kim, Sung Jun Ahn, Dong-Seok Kim, Kyung-Yul Lee

Journal: Yonsei Med. J.. 2015 Sep;56(5):1322-7.

 

Leptomeningeal collateral, in moyamoya disease (MMD), appears as an ivy sign on fluid-attenuated inversion-recovery (FLAIR) images. There has been little investigation into the relationship between presentation of ivy signs and old brain lesions. We aimed to evaluate clinical significance ...

Last Updated: 10 Aug 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Moyamoya disease" returned 27 free, full-text review articles on human participants. First 3 results:

Research Progress of Moyamoya Disease in Children.
 

Author(s): Jianmin Piao, Wei Wu, Zhongxi Yang, Jinlu Yu

Journal:

 

During the onset of Moyamoya disease (MMD), progressive occlusion occurs at the end of the intracranial internal carotid artery, and compensatory net-like abnormal vessels develop in the skull base, generating the corresponding clinical symptoms. MMD can affect both children and adults, ...

Last Updated: 16 Jul 2015

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Current status of revascularization surgery for Moyamoya disease: special consideration for its 'internal carotid-external carotid (IC-EC) conversion' as the physiological reorganization system.
 

Author(s): Miki Fujimura, Teiji Tominaga

Journal: Tohoku J. Exp. Med.. 2015 ;236(1):45-53.

 

Moyamoya disease is a chronic cerebrovascular disease with unknown etiology, which is characterized by bilateral steno-occlusive changes at the terminal portion of the internal carotid artery and an abnormal vascular network formation at the base of the brain. Moyamoya disease is ...

Last Updated: 14 May 2015

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Treatment strategies for aneurysms associated with moyamoya disease.
 

Author(s): Lei Zhang, Kan Xu, Yandong Zhang, Xin Wang, Jinlu Yu

Journal:

 

The treatment of aneurysms associated with moyamoya disease (MMD) is difficult for neurosurgeons, and little is known of strategy options. This report constitutes a comprehensive review of the literature. We summarize the known treatments and their clinical outcomes according to the ...

Last Updated: 14 Feb 2015

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Moyamoya Disease Biomarkers in Patients With Intracranial Atherosclerotic Stroke
 

Status: Recruiting

Condition Summary: Moyamoya Disease; Intracranial Atherosclerotic Stroke; Intracranial Steno-occlusive Disease

 

Last Updated: 26 Feb 2014

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Neurocognitive and Radiological Assessments in Adult Moyamoya Undergoing Surgery
 

Status: Recruiting

Condition Summary: Moyamoya Disease

 

Last Updated: 16 Mar 2016

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Sevoflurane and Hyperperfusion Syndrome
 

Status: Not yet recruiting

Condition Summary: Hyperperfusion Syndrome; Moyamoya Disease

 

Last Updated: 26 Jul 2015

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