Breast Cancer

Common Name(s)

Breast Cancer, Cancer, Breast

Breast cancer is a type of cancerous tumor originating in the breast of an individual. It can develop in different areas of the breast (the ducts, the lobules, or the tissue in between) and later spread to different parts of the body if invasive. After skin cancer, breast cancer is the most commonly diagnosed cancer in women in the United States. Although male breast cancer is also a possibility, it occurs less frequently and as a result it can lead to poorer outcomes due to late diagnosis. There are several types of breast cancer that can be categorized as non-invasive, invasive, recurrent, and metastatic breast cancers.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Breast Cancer" for support, advocacy or research.

Inflammatory Breast Cancer Research Foundation

Our mission is to assist scientists and researchers in their quest to determine the definitive causes of inflammatory breast cancer. The Inflammatory Breast Cancer Research Foundation seeks to assist them in their work so effective and meaningful detection and diagnosis, prevention and treatment can be pursued and achieved.

Last Updated: 29 Apr 2014

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1 in 9: The Long Island Breast Cancer Action Coalition

1 in 9 is an advocacy organization that keeps the concerns about the breast cancer epidemic in the forefront. 1 in 9 also promotes action toward finding causes & cures for the eradication of breast cancer.

Last Updated: 24 Dec 2012

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4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

Last Updated: 12 Dec 2012

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Breast Cancer Connections

We support people touched by breast or ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

Last Updated: 22 Apr 2014

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Breast Cancer Options

Our mission is to educate breast cancer patients about effective treatment options, to advocate for and support informed patient choice and to promote public awareness regarding cancer risk reduction.

Last Updated: 28 Oct 2012

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Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

Last Updated: 25 Mar 2013

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Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

Last Updated: 26 Dec 2012

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Dr. Susan Love Research Foundation

The Mission of the Dr. Susan Love Research Foundation is to eradicate breast cancer and improve the quality of women's health through innovative research, education and advocacy.

Last Updated: 1 Mar 2013

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FORCE: Facing Our Risk of Cancer Empowered

FORCE is a national nonprofit dedicated to fighting hereditary breast and ovarian cancer. With 50 outreach groups throughout the U.S., and international affiliates, FORCE programs provide support, education, advocacy, awareness and research specific to hereditary cancers. Our programs serve anyone with a BRCA mutation or a family history of cancer. FORCE was founded on the principle that no one should have to face hereditary breast and ovarian cancer alone.

Last Updated: 5 May 2014

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HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

Last Updated: 3 Oct 2013

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Kommah Seray Inflammatory Breast Cancer Foundation

To raise awareness of Inflammatory Breast Cancer and meet the immediate needs of active cancer patients by providing assistance and support. Additionally, the foundation will work toward educating medical professionals and the community at large on how to detect Inflammatory Breast Cancer.

Last Updated: 26 Mar 2013

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Latina Breast Cancer Agency

Assist low-income women to acquire breast cancer screening services including treatment at no cost and without barriers.

Last Updated: 1 Oct 2013

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Living Beyond Breast Cancer

To empower all women affected by breast cancer to live as long as possible with the best quality of life.

Last Updated: 26 Mar 2013

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National Breast Cancer Coalition

NBCC's mission is to eradicate breast cancer, by focusing the administration, U.S. Congress, research institutions and consumer advocates on breast cancer. NBCC encourages all those concerned about this disease to become advocates for action and change.

Last Updated: 24 Nov 2009

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SHARE

SHARE helps people through breast or ovarian cancer, from diagnosis through treatment and post-treatment, offering the unique support of survivors who've been there. All of SHARE's services are free of charge and include telephone support, educational programs, support groups, and public-health initiatives. Visit us at www.sharecancersupport.org or call our toll-free helplines at 866-891-2392.

Last Updated: 20 Feb 2013

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Sharsheret

Sharsheret is a national not-for-profit organization supporting young Jewish women and their families facing breast cancer. Our mission is to offer a community of support to women, of all Jewish backgrounds, diagnosed with breast cancer or at increased genetic risk, by fostering culturally-relevant individualized connections with networks of peers, health professionals, and related resources.

Last Updated: 5 Mar 2013

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Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

Last Updated: 6 Nov 2012

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Susan G. Komen for the Cure

Komen for the Cure is the world's largest grassroots network of breast cancer survivors and activists fighting to save lives, empower people, ensure quality care for all and energize science to find the cures.

Last Updated: 6 Oct 2013

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Virginia Breast Cancer Foundation

The Virginia Breast Cancer Foundation (VBCF), founded in 1991, is a nonprofit 501(c)3 organization committed to the eradication of breast cancer through education and advocacy. Our goals are to establish the end of breast cancer as a state and national priority, to advocate for the collective needs of people affected by breast cancer and to educate all Virginians on the facts about breast cancer.

Last Updated: 1 Nov 2012

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werathah

To provide support and health education to patients and their families with genetic and congenital disorders

Last Updated: 1 May 2013

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Young Survival Coalition

Young Survival Coalition (YSC) is the premier global organization dedicated to the critical issues unique to young women who are diagnosed with breast cancer. Providing an informative interactive website, educational resources and programs, as well as local support services across the United States, it is YSC's goal that young women feel supported, empowered and hopeful and most importantly, are not left to face breast cancer alone.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Breast Cancer" for support, advocacy or research.

Inflammatory Breast Cancer Research Foundation

Our mission is to assist scientists and researchers in their quest to determine the definitive causes of inflammatory breast cancer. The Inflammatory Breast Cancer Research Foundation seeks to assist them in their work so effective and meaningful detection and diagnosis, prevention and treatment can be pursued and achieved.

http://www.ibcresearch.org

Last Updated: 29 Apr 2014

View Details
Logo
1 in 9: The Long Island Breast Cancer Action Coalition

1 in 9 is an advocacy organization that keeps the concerns about the breast cancer epidemic in the forefront. 1 in 9 also promotes action toward finding causes & cures for the eradication of breast cancer.

http://www.1in9.org

Last Updated: 24 Dec 2012

View Details
4th Angel Mentoring Program

Learning that you have cancer can be an overwhelming experience – one that leaves you frightened, vulnerable and alone. The 4th Angel Mentoring Program offers free, one-on-one, confidential outreach and support from someone who has successfully made the same journey you are about to begin – the journey towards recovery. This specially trained volunteer and cancer survivor – your 4th Angel – is someone who will talk and listen in a supportive setting. The 4th Angel Mentoring Program is telephone based, so you can be connect with an angel anywhere in the country. 4th Angel Mentoring Program is part of The Scott Hamilton CARES Initiative, a national non-profit organizat

http://www.4thangel.org

Last Updated: 12 Dec 2012

View Details
Logo
Breast Cancer Connections

We support people touched by breast or ovarian cancer by providing comprehensive, personalized services in an atmosphere of warmth and compassion.

http://www.bcconnections.org

Last Updated: 22 Apr 2014

View Details
Breast Cancer Options

Our mission is to educate breast cancer patients about effective treatment options, to advocate for and support informed patient choice and to promote public awareness regarding cancer risk reduction.

http://www.breastcanceroptions.org

Last Updated: 28 Oct 2012

View Details
Breast Friends

Breast Friends ensures that no woman goes through cancer alone. We are a unique resource for women, their family, friends, co-workers and community minimizing the fear and isolation of cancer. For over a decade our programs have empowered thousands with emotional support and hope. We are survivors and professionals helping others celebrate the joy of life.

http://www.breastfriends.org

Last Updated: 25 Mar 2013

View Details
Center for Jewish Genetics

The Center is dedicated to gathering and disseminating knowledge about Jewish genetic disorders and hereditary cancers. Its mission is to educate and serve health care professionals, clergy and the Jewish community.

http://www.jewishgenetics.org

Last Updated: 26 Dec 2012

View Details
Dr. Susan Love Research Foundation

The Mission of the Dr. Susan Love Research Foundation is to eradicate breast cancer and improve the quality of women's health through innovative research, education and advocacy.

http://www.dslrf.org

Last Updated: 1 Mar 2013

View Details
FORCE: Facing Our Risk of Cancer Empowered

FORCE is a national nonprofit dedicated to fighting hereditary breast and ovarian cancer. With 50 outreach groups throughout the U.S., and international affiliates, FORCE programs provide support, education, advocacy, awareness and research specific to hereditary cancers. Our programs serve anyone with a BRCA mutation or a family history of cancer. FORCE was founded on the principle that no one should have to face hereditary breast and ovarian cancer alone.

http://www.facingourrisk.org

Last Updated: 5 May 2014

View Details
HealthyWomen

HealthyWomen (HW) is the nation's leading independent health information source for women. Our core mission is to educate, inform and empower women to make smart health choices for themselves and their families. For more than 20 years, millions of women have been coming to HW for answers to their most pressing and personal health care questions. Through our wide array of online and print publications, HW provides health information that is original, objective, reviewed by medical experts and reflective of the advances in evidence-based health research.

http://www.healthywomen.org

Last Updated: 3 Oct 2013

View Details
Kommah Seray Inflammatory Breast Cancer Foundation

To raise awareness of Inflammatory Breast Cancer and meet the immediate needs of active cancer patients by providing assistance and support. Additionally, the foundation will work toward educating medical professionals and the community at large on how to detect Inflammatory Breast Cancer.

http://www.ksibcf.org

Last Updated: 26 Mar 2013

View Details
Logo
Latina Breast Cancer Agency

Assist low-income women to acquire breast cancer screening services including treatment at no cost and without barriers.

http://www.latinabca.org

Last Updated: 1 Oct 2013

View Details
Living Beyond Breast Cancer

To empower all women affected by breast cancer to live as long as possible with the best quality of life.

http://www.lbbc.org

Last Updated: 26 Mar 2013

View Details
Logo
National Breast Cancer Coalition

NBCC's mission is to eradicate breast cancer, by focusing the administration, U.S. Congress, research institutions and consumer advocates on breast cancer. NBCC encourages all those concerned about this disease to become advocates for action and change.

http://www.natlbcc.org

Last Updated: 24 Nov 2009

View Details
SHARE

SHARE helps people through breast or ovarian cancer, from diagnosis through treatment and post-treatment, offering the unique support of survivors who've been there. All of SHARE's services are free of charge and include telephone support, educational programs, support groups, and public-health initiatives. Visit us at www.sharecancersupport.org or call our toll-free helplines at 866-891-2392.

http://www.sharecancersupport.org

Last Updated: 20 Feb 2013

View Details
Sharsheret

Sharsheret is a national not-for-profit organization supporting young Jewish women and their families facing breast cancer. Our mission is to offer a community of support to women, of all Jewish backgrounds, diagnosed with breast cancer or at increased genetic risk, by fostering culturally-relevant individualized connections with networks of peers, health professionals, and related resources.

http://www.sharsheret.org

Last Updated: 5 Mar 2013

View Details
Stupid Cancer

Founded by and for young adult survivors, the I'm Too Young For This! Cancer Foundation (i[2]y), is the nation's leading grassroots advocate for the next generation of cancer survivors and their caregivers in their late teens, 20s and 30s. A TIME Magazine Best 50 Website, we have helped bring the cause of 'young adult cancer' to the national spotlight and rallied a brand new generation of activists to give voice to our forgotten population. Our mission is to empower young adults affected by cancer.

http://stupidcancer.org

Last Updated: 6 Nov 2012

View Details
Logo
Susan G. Komen for the Cure

Komen for the Cure is the world's largest grassroots network of breast cancer survivors and activists fighting to save lives, empower people, ensure quality care for all and energize science to find the cures.

http://ww5.komen.org/

Last Updated: 6 Oct 2013

View Details
Logo
Virginia Breast Cancer Foundation

The Virginia Breast Cancer Foundation (VBCF), founded in 1991, is a nonprofit 501(c)3 organization committed to the eradication of breast cancer through education and advocacy. Our goals are to establish the end of breast cancer as a state and national priority, to advocate for the collective needs of people affected by breast cancer and to educate all Virginians on the facts about breast cancer.

http://www.vbcf.org

Last Updated: 1 Nov 2012

View Details
werathah

To provide support and health education to patients and their families with genetic and congenital disorders

http://www.werathah.com

Last Updated: 1 May 2013

View Details
Logo
Young Survival Coalition

Young Survival Coalition (YSC) is the premier global organization dedicated to the critical issues unique to young women who are diagnosed with breast cancer. Providing an informative interactive website, educational resources and programs, as well as local support services across the United States, it is YSC's goal that young women feel supported, empowered and hopeful and most importantly, are not left to face breast cancer alone.

http://www.youngsurvival.org/

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
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General Resources

If breast or ovarian cancer runs in your family

This brochure discusses the basics of hereditary cancers, including signs, genetic counseling and genetic testing.

Updated 4 Oct 2012

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Se Valiente, Son Tus Senos

An illustrated Spanish-language publication that dispels common myths about breast cancer in Latino communities.

Uploaded By: SHARE

Updated 25 Jan 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Breast Cancer" returned 26653 free, full-text research articles on human participants. First 3 results:

Breast-cancer predisposition in multiple endocrine neoplasia type 1.
 

Author(s): Koen M A Dreijerink, Pierre Goudet, John R Burgess, Gerlof D Valk,

Journal: N. Engl. J. Med.. 2014 Aug;371(6):583-4.

 

Last Updated: 7 Aug 2014

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Therapeutic targeting of integrin αvβ6 in breast cancer.
 

Author(s): Kate M Moore, Gareth J Thomas, Stephen W Duffy, Jane Warwick, Rhian Gabe, Patrick Chou, Ian O Ellis, Andrew R Green, Syed Haider, Kellie Brouilette, Antonio Saha, Sabari Vallath, Rebecca Bowen, Claude Chelala, Diana Eccles, William J Tapper, Alastair M Thompson, Phillip Quinlan, Lee Jordan, Cheryl Gillett, Adam Brentnall, Shelia Violette, Paul H Weinreb, Jane Kendrew, Simon T Barry, Ian R Hart, J Louise Jones, John F Marshall

Journal:

 

Integrin αvβ6 promotes migration, invasion, and survival of cancer cells; however, the relevance and role of αvβ6 has yet to be elucidated in breast cancer.

Last Updated: 30 Jun 2014

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Effects of obesity on transcriptomic changes and cancer hallmarks in estrogen receptor-positive breast cancer.
 

Author(s): Enrique Fuentes-Mattei, Guermarie Velazquez-Torres, Liem Phan, Fanmao Zhang, Ping-Chieh Chou, Ji-Hyun Shin, Hyun Ho Choi, Jiun-Sheng Chen, Ruiying Zhao, Jian Chen, Chris Gully, Colin Carlock, Yuan Qi, Ya Zhang, Yun Wu, Francisco J Esteva, Yongde Luo, Wallace L McKeehan, Joe Ensor, Gabriel N Hortobagyi, Lajos Pusztai, W Fraser Symmans, Mong-Hong Lee, Sai-Ching Jim Yeung

Journal:

 

Obesity increases the risk of cancer death among postmenopausal women with estrogen receptor-positive (ER+) breast cancer, but the direct evidence for the mechanisms is lacking. The purpose of this study is to demonstrate direct evidence for the mechanisms mediating this epidemiologic phenomenon.

Last Updated: 24 Jun 2014

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Breast Cancer" returned 2360 free, full-text review articles on human participants. First 3 results:

A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.
 

Author(s): Chao Liu, Sriganesh Srihari, Kim-Anh Lê Cao, Georgia Chenevix-Trench, Peter T Simpson, Mark A Ragan, Kum Kum Khanna

Journal: Nucleic Acids Res.. 2014 ;42(10):6106-27.

 

DNA-damage response machinery is crucial to maintain the genomic integrity of cells, by enabling effective repair of even highly lethal lesions such as DNA double-strand breaks (DSBs). Defects in specific genes acquired through mutations, copy-number alterations or epigenetic changes ...

Last Updated: 11 Jun 2014

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Helping women to good health: breast cancer, omega-3/omega-6 lipids, and related lifestyle factors.
 

Author(s): Michel de Lorgeril, Patricia Salen

Journal:

 

In addition to genetic predisposition and sex hormone exposure, physical activity and a healthy diet play important roles in breast cancer (BC). Increased intake of omega-3 fatty acids (n-3) associated with decreased omega-6 (n-6), resulting in a higher n-3/n-6 ratio compared with ...

Last Updated: 27 Mar 2014

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Gold nanoparticles in breast cancer treatment: promise and potential pitfalls.
 

Author(s): Jihyoun Lee, Dev Kumar Chatterjee, Min Hyuk Lee, Sunil Krishnan

Journal: Cancer Lett.. 2014 May;347(1):46-53.

 

Despite remarkable achievements in the treatment of breast cancer, some obstacles still remain. Gold nanoparticles may prove valuable in addressing these problems owing to their unique characteristics, including their enhanced permeability and retention in tumor tissue, their light ...

Last Updated: 31 Mar 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)
 

Status: Recruiting

Condition Summary: Breast Tumor; Breast Cancer; Cancer of the Breast; Estrogen Receptor- Negative Breast Cancer; HER2- Negative Breast Cancer; Progesterone Receptor- Negative Breast Cancer; Recurrent Breast Cancer; Stage IV Breast Cancer; Triple-negative Breast Cancer; Triple-negative Metastatic Breast Cancer; Metastatic Breast Cancer

 

Last Updated: 16 Jun 2014

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GDC-0941 and Cisplatin in Treating Patients With Androgen Receptor-Negative Triple Negative Metastatic Breast Cancer
 

Status: Recruiting

Condition Summary: Estrogen Receptor Negative Breast Cancer; Human Epidermal Growth Factor 2 Negative Carcinoma of Breast; Triple Negative Breast Cancer; Recurrent Breast Cancer; Stage IV Breast Cancer; Triple-negative Breast Cancer

 

Last Updated: 10 Feb 2014

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Eribulin Versus Vinorelbine in Subjects With Locally Recurrent or Metastatic Breast Cancer Previously Treated With Anthracyclines and Taxanes
 

Status: Recruiting

Condition Summary: HER2-Negative Breast Cancer; Triple Negative Breast Cancer; Breast Cancer; Cancer of Breast; Breast Tumors

 

Last Updated: 22 Aug 2014

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