Interstitial cystitis

Common Name(s)

Interstitial cystitis

Interstitial cystitis (IC) is a condition that causes discomfort or pain in the bladder and abdomen. Symptoms may vary, but often include an urgent or frequent need to urinate. Many of the individuals affected by IC are women. Because IC varies so much in symptoms and severity, most researchers believe it is not one, but several diseases. In recent years, scientists have started to use the terms bladder pain syndrome (BPS) or painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. While there is no cure for IC/PBS, in many cases, the symptoms can be managed. Treatments include dietary and lifestyle changes; distending, or inflating, the bladder; bathing the inside of the bladder with a medicine solution; oral medicines and in rare cases, surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

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Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

Last Updated: 19 Feb 2013

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

Logo
Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

http://www.ichelp.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial cystitis" returned 248 free, full-text research articles on human participants. First 3 results:

Pulsed radiofrequency treatment of the superior hypogastric plexus in an interstitial cystitis patient with chronic pain and symptoms refractory to oral and intravesical medications and bladder hydrodistension: A case report.
 

Author(s): Jong Hae Kim, Eugene Kim, Bong Il Kim

Journal: Medicine (Baltimore). 2016 Dec;95(49):e5549.

 

A variety of therapeutic modalities are available for the treatment of interstitial cystitis. However, among them, the less invasive therapies are usually ineffective, whereas the invasive ones carry potential risks of serious side effects and complications. Pulsed radiofrequency ...

Last Updated: 8 Dec 2016

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The Role of Immunoglobulin E in the Pathogenesis of Ketamine Related Cystitis and Ulcerative Interstitial Cystitis: An Immunohistochemical Study.
 

Author(s): Jia-Fong Jhang, Yung-Hsiang Hsu, Yuan-Hong Jiang, Hann-Chorng Kuo

Journal: Pain Physician. 2016 05;19(4):E581-7.

 

A previous study revealed elevated serum Immunoglobulin E (IgE) in ketamine related cystitis (KC) patients. IgE might participate the pathogenesis of different types of bladder pain syndromes, including KC and interstitial cystitis (IC).

Last Updated: 27 May 2016

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Revisiting the Role of Potassium Sensitivity Testing and Cystoscopic Hydrodistention for the Diagnosis of Interstitial Cystitis.
 

Author(s): Yuan-Hong Jiang, Jia-Fong Jhang, Hann-Chorng Kuo

Journal:

 

To revisit the diagnostic roles of cystoscopic hydrodistention and the potassium sensitivity test (PST) for the diagnosis of interstitial cystitis (IC).

Last Updated: 22 Mar 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial cystitis" returned 29 free, full-text review articles on human participants. First 3 results:

Systematic Review and Meta-Analysis of Intravesical Hyaluronic Acid and Hyaluronic Acid/Chondroitin Sulfate Instillation for Interstitial Cystitis/Painful Bladder Syndrome.
 

Author(s): Jung-Soo Pyo, Won Jin Cho

Journal: Cell. Physiol. Biochem.. 2016 ;39(4):1618-25.

 

To assess the efficacy of intravesical hyaluronic acid (HA) and HA/chondroitin sulfate (CS) instillation in patients with interstitial cystitis/painful bladder syndrome by systematic review and meta-analysis.

Last Updated: 16 Sep 2016

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Beyond a Simple Anesthetic Effect: Lidocaine in the Diagnosis and Treatment of Interstitial Cystitis/bladder Pain Syndrome.
 

Author(s): Richard A Henry, Alvaro Morales, Catherine M Cahill

Journal: Urology. 2015 May;85(5):1025-33.

 

Intravesical local anesthetics, in a wide variety of combinations, are increasingly used to treat patients with interstitial cystitis-bladder pain syndrome (IC/BPS). Lidocaine has demonstrated properties that block the neuroinflammatory cycle associated with IC/BPS at many of the ...

Last Updated: 28 Apr 2015

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Painful bladder syndrome/interstitial cystitis: aetiology, evaluation and management.
 

Author(s): William Rourke, Shahid Aziz Anwer Khan, Kamran Ahmed, Shikohe Masood, Prokar Dasgupta, Muhammad Shamim Khan

Journal:

 

Interstitial cystitis or bladder pain syndrome (BPS) is often a chronic debilitating condition characterised by predominantly storage symptoms and associated frequently with pelvic pain that varies with bladder filling. The aetiology is uncertain as the condition occurs in the absence ...

Last Updated: 14 Jul 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 9 Feb 2017

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Evaluation of Intravesical LP08 in Patients With Interstitial Cystitis/Painful Bladder Syndrome
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 27 May 2016

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Interstitial Cystitis (IC)-Like Findings With Hydrodistension
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 4 Oct 2016

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