Interstitial cystitis

Common Name(s)

Interstitial cystitis

Interstitial cystitis (IC) is a condition that causes discomfort or pain in the bladder and abdomen. Symptoms may vary, but often include an urgent or frequent need to urinate. Many of the individuals affected by IC are women. Because IC varies so much in symptoms and severity, most researchers believe it is not one, but several diseases. In recent years, scientists have started to use the terms bladder pain syndrome (BPS) or painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. While there is no cure for IC/PBS, in many cases, the symptoms can be managed. Treatments include dietary and lifestyle changes; distending, or inflating, the bladder; bathing the inside of the bladder with a medicine solution; oral medicines and in rare cases, surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

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Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

Last Updated: 19 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

Logo
Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

http://www.ichelp.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial cystitis" returned 234 free, full-text research articles on human participants. First 3 results:

Hunner-Type (Classic) Interstitial Cystitis: A Distinct Inflammatory Disorder Characterized by Pancystitis, with Frequent Expansion of Clonal B-Cells and Epithelial Denudation.
 

Author(s): Daichi Maeda, Yoshiyuki Akiyama, Teppei Morikawa, Akiko Kunita, Yasunori Ota, Hiroto Katoh, Aya Niimi, Akira Nomiya, Shumpei Ishikawa, Akiteru Goto, Yasuhiko Igawa, Masashi Fukayama, Yukio Homma

Journal:

 

Interstitial cystitis (IC) is a chronic bladder disease with urinary frequency, bladder discomfort or bladder pain of unknown etiology. Based on cystoscopic findings, patients with IC are classified as either Hunner-type/classic IC (HIC), presenting with a specific Hunner lesion, ...

Last Updated: 21 Nov 2015

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Correlation Between Bladder Pain Syndrome/Interstitial Cystitis and Pelvic Inflammatory Disease.
 

Author(s): Shiu-Dong Chung, Chao-Hsiang Chang, Peir-Haur Hung, Chi-Jung Chung, Chih-Hsin Muo, Chao-Yuan Huang

Journal: Medicine (Baltimore). 2015 Nov;94(46):e1878.

 

Pelvic inflammatory disease (PID) has been investigated in Western countries and identified to be associated with chronic pelvic pain and inflammation. Bladder pain syndrome/interstitial cystitis (BPS/IC) is a complex syndrome that is significantly more prevalent in women than in ...

Last Updated: 20 Nov 2015

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Long-Term Efficacy and Safety of Repeated Intravescial OnabotulinumtoxinA Injections Plus Hydrodistention in the Treatment of Interstitial Cystitis/Bladder Pain Syndrome.
 

Author(s): Cheng-Ling Lee, Hann-Chorng Kuo

Journal:

 

Intravesical onabotulinumtoxinA (BoNT-A) injection can relieve symptoms of interstitial cystitis/bladder pain syndrome (IC/BPS), but lacks sustainability. Repeated injections have been shown to provide a superior outcome to a single injection, but data on long-term efficacy and safety ...

Last Updated: 28 Oct 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial cystitis" returned 27 free, full-text review articles on human participants. First 3 results:

Painful bladder syndrome/interstitial cystitis: aetiology, evaluation and management.
 

Author(s): William Rourke, Shahid Aziz Anwer Khan, Kamran Ahmed, Shikohe Masood, Prokar Dasgupta, Muhammad Shamim Khan

Journal:

 

Interstitial cystitis or bladder pain syndrome (BPS) is often a chronic debilitating condition characterised by predominantly storage symptoms and associated frequently with pelvic pain that varies with bladder filling. The aetiology is uncertain as the condition occurs in the absence ...

Last Updated: 14 Jul 2014

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Gynecological disorders in bladder pain syndrome/interstitial cystitis patients.
 

Author(s): Mauro Cervigni, Franca Natale

Journal: Int. J. Urol.. 2014 Apr;21 Suppl 1():85-8.

 

Bladder pain syndrome/interstitial cystitis, a chronic inflammatory condition of the bladder, is the source of pain in over 30% of female patients with chronic pelvic pain. The aim of the present study was to evaluate the most frequent associations between bladder pain syndrome/interstitial ...

Last Updated: 8 May 2014

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Potential therapeutic effect of intravesical botulinum toxin type‚ÄČA on bladder pain syndrome/interstitial cystitis.
 

Author(s): Jia-Fong Jhang, Yuan-Hong Jiang, Hann-Chorng Kuo

Journal: Int. J. Urol.. 2014 Apr;21 Suppl 1():49-55.

 

Bladder pain syndrome/interstitial cystitis is characterized by bladder pain associated with urgency, frequency, nocturia, dysuria and sterile urine. Recent studies have shown that these bladder dysfunctions could originate from chronic inflammation or urothelial insult and proceed ...

Last Updated: 8 May 2014

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Intravesicular Onabotulinumtoxin A in Interstitial Cystitis
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 10 Dec 2015

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Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome
 

Status: Recruiting

Condition Summary: Interstitial Cystitis; Painful Bladder Syndrome

 

Last Updated: 23 Apr 2013

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Osteopathic Manipulation for Female Interstitial Cystitis Patients With Sacroiliac Joint Dysfunction
 

Status: Recruiting

Condition Summary: Interstitial Cystitis; Sacroiliac Joint Somatic Dysfunction

 

Last Updated: 11 Apr 2014

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