Interstitial cystitis

Common Name(s)

Interstitial cystitis

Interstitial cystitis (IC) is a condition that causes discomfort or pain in the bladder and abdomen. Symptoms may vary, but often include an urgent or frequent need to urinate. Many of the individuals affected by IC are women. Because IC varies so much in symptoms and severity, most researchers believe it is not one, but several diseases. In recent years, scientists have started to use the terms bladder pain syndrome (BPS) or painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. While there is no cure for IC/PBS, in many cases, the symptoms can be managed. Treatments include dietary and lifestyle changes; distending, or inflating, the bladder; bathing the inside of the bladder with a medicine solution; oral medicines and in rare cases, surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

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Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

Last Updated: 19 Feb 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

Logo
Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

http://www.ichelp.org

Last Updated: 19 Feb 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial cystitis" returned 261 free, full-text research articles on human participants. First 3 results:

Somatoform disorder as a predictor of interstitial cystitis/bladder pain syndrome: Evidence from a nested case-control study and a retrospective cohort study.
 

Author(s): I-Chun Chen, Ming-Huei Lee, Hsuan-Hung Lin, Shang-Liang Wu, Kun-Min Chang, Hsiu-Ying Lin

Journal: Medicine (Baltimore). 2017 May;96(18):e6304.

 

Interstitial cystitis/bladder pain syndrome (IC/BPS) has several well-known comorbid psychiatric manifestations, including insomnia, anxiety, and depression. We hypothesized that somatoform disorder, which is a psychosomatic disease, can be used as a sensitive psychiatric phenotype ...

Last Updated: 4 May 2017

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Characterizing Health Care Utilization, Direct Costs, and Comorbidities Associated with Interstitial Cystitis: A Retrospective Claims Analysis.
 

Author(s): Amy Tung, Zsolt Hepp, Aasthaa Bansal, Emily Beth Devine

Journal: J Manag Care Spec Pharm. 2017 Apr;23(4):474-482.

 

Interstitial cystitis (IC) is a debilitating condition that affects up to 5% of the U.S.

Last Updated: 27 Mar 2017

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A prospective randomized controlled multicentre trial comparing intravesical DMSO and chondroïtin sulphate 2% for painful bladder syndrome/interstitial cystitis.
 

Author(s): Manuela Tutolo, Enrico Ammirati, Giulia Castagna, Katrien Klockaerts, Hendrik Plancke, Dieter Ost, Frank Van der Aa, Dirk De Ridder

Journal: Int Braz J Urol. ;43(1):134-141.

 

To compare effectiveness of intravesical chondroïtin sulphate (CS) 2% and dimethyl sulphoxide (DMSO) 50% in patients with painful bladder syndrome/interstitial cystitis (PBS/IC).

Last Updated: 26 Jan 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial cystitis" returned 31 free, full-text review articles on human participants. First 3 results:

Systematic Review and Meta-Analysis of Intravesical Hyaluronic Acid and Hyaluronic Acid/Chondroitin Sulfate Instillation for Interstitial Cystitis/Painful Bladder Syndrome.
 

Author(s): Jung-Soo Pyo, Won Jin Cho

Journal: Cell. Physiol. Biochem.. 2016 ;39(4):1618-25.

 

To assess the efficacy of intravesical hyaluronic acid (HA) and HA/chondroitin sulfate (CS) instillation in patients with interstitial cystitis/painful bladder syndrome by systematic review and meta-analysis.

Last Updated: 16 Sep 2016

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Intravesical Botulinum Toxin A Injections for Bladder Pain Syndrome/Interstitial Cystitis: A Systematic Review and Meta-Analysis of Controlled Studies.
 

Author(s): Junpeng Wang, Qiang Wang, Qinghui Wu, Yang Chen, Peng Wu

Journal:

 

BACKGROUND The role of intravesical botulinum toxin A (BTX-A) injections in bladder pain syndrome/interstitial cystitis (BPS/IC) has not been clearly defined. The aim of this study was to evaluate high-level evidence regarding the efficacy and safety of BTX-A injections for BPS/IC. ...

Last Updated: 14 Sep 2016

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A systematic review and meta-analysis on the efficacy of intravesical therapy for bladder pain syndrome/interstitial cystitis.
 

Author(s): Jayanta M Barua, Ignacio Arance, Javier C Angulo, Claus R Riedl

Journal: Int Urogynecol J. 2016 Aug;27(8):1137-47.

 

Bladder pain syndrome/interstitial cystitis (BPS/IC) is a chronic disease characterised by persistent irritating micturition symptoms and pain. The objective was to compare the clinical efficacy of currently available products for intravesical therapy of BPS/IC and to assess their ...

Last Updated: 16 Jul 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Efficacy of Urine Biomarker in Patient With Interstitial Cystitis/Painful Bladder Syndrome (Pilot Study)
 

Status: Recruiting

Condition Summary: Chronic Interstitial Cystitis

 

Last Updated: 6 Jul 2017

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Intravesicular Onabotulinumtoxin A in Interstitial Cystitis
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 2 Nov 2017

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Evaluation of Intravesical LP08 in Patients With Interstitial Cystitis/Painful Bladder Syndrome
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 11 Sep 2017

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