Interstitial cystitis

Common Name(s)

Interstitial cystitis

Interstitial cystitis (IC) is a condition that causes discomfort or pain in the bladder and abdomen. Symptoms may vary, but often include an urgent or frequent need to urinate. Many of the individuals affected by IC are women. Because IC varies so much in symptoms and severity, most researchers believe it is not one, but several diseases. In recent years, scientists have started to use the terms bladder pain syndrome (BPS) or painful bladder syndrome (PBS) to describe cases with painful urinary symptoms that may not meet the strictest definition of IC. While there is no cure for IC/PBS, in many cases, the symptoms can be managed. Treatments include dietary and lifestyle changes; distending, or inflating, the bladder; bathing the inside of the bladder with a medicine solution; oral medicines and in rare cases, surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

Logo
Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
Top

How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Interstitial cystitis" for support, advocacy or research.

Logo
Interstitial Cystitis Association

The Interstitial Cystitis Association (ICA) advocates for research dedicated to discovery of a cure and better treatments, raises awareness, and serves as a central hub for the healthcare providers, researchers and millions of patients who suffer with constant urinary urgency and frequency and extreme bladder pain called IC, or interstitial cystitis. Vision Conquering IC. Changing lives. Mission Early diagnosis and optimal care with dignity for people affected by IC

http://www.ichelp.org

Last Updated: 19 Feb 2013

View Details

 

General Support Organizations

Not finding the support you need? Show General Support Organizations

 
 
 
 
Top

Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Interstitial cystitis" returned 97 free, full-text research articles on human participants. First 3 results:

Increased pro-inflammatory cytokines, C-reactive protein and nerve growth factor expressions in serum of patients with interstitial cystitis/bladder pain syndrome.
 

Author(s): Yuan-Hong Jiang, Chung-Hsin Peng, Hsin-Tzu Liu, Hann-Chorng Kuo

Journal:

 

The etiology and pathogenesis of interstitial cystitis/bladder pain syndrome (IC/BPS) are unclear. Chronic inflammation is considered the main pathology of IC/BPS. This study measured the serum c-reactive protein (CRP), nerve growth factor (NGF) and pro-inflammatory cytokine/chemokine ...

Last Updated: 22 Oct 2013

Go To URL
Bladder pain syndrome/interstitial cystitis is associated with hyperthyroidism.
 

Author(s): Shiu-Dong Chung, Shih-Ping Liu, Ching-Chun Lin, Hsien-Chang Li, Herng-Ching Lin

Journal:

 

Although the etiology of bladder pain syndrome/interstitial cystitis (BPS/IC) is still unclear, a common theme with BPS/IC patients is comorbid disorders which are related to the autonomic nervous system that connects the nervous system to end-organs. Nevertheless, no study to date ...

Last Updated: 30 Aug 2013

Go To URL
Consequences of interstitial cystitis/bladder pain symptoms on women's work participation and income: results from a national household sample.
 

Author(s): Megan K Beckett, Marc N Elliott, J Quentin Clemens, Brett Ewing, Sandra H Berry

Journal: J. Urol.. 2014 Jan;191(1):83-8.

 

We describe differences in work participation and income by bladder symptom impact and comorbidities among women with interstitial cystitis/bladder pain syndrome.

Last Updated: 16 Dec 2013

Go To URL

Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Interstitial cystitis" returned 13 free, full-text review articles on human participants. First 3 results:

The potential of non-adrenergic, non-cholinergic targets in the treatment of interstitial cystitis/painful bladder syndrome.
 

Author(s): R Vesela, P Aronsson, M Andersson, V Wsol, G Tobin

Journal: J. Physiol. Pharmacol.. 2012 Jun;63(3):209-16.

 

Regulation of bladder function involves both divisions of the autonomic nervous system. However, in addition to the classical autonomic transmitters, noradrenaline and acetylcholine, other autonomic transmitters and other signalling components play important roles in physiology and ...

Last Updated: 13 Jul 2012

Go To URL
[Intravesical therapy of heparin and lidocaine for interstitial cystitis : a case report].
 

Author(s): Tomohiro Matsuo, Yohei Shida, Yasushi Hayashida, Hideki Sakai

Journal: Hinyokika Kiyo. 2011 Sep;57(9):513-6.

 

Interstitial cystitis (IC) is a chronic inflammatory condition of the urinary bladder, and its treatment has many uncertainties. We report a case of IC treated with intravesical instillation of heparin and alkalized lidocaine. A 64-year-old woman presented with urinary frequency and ...

Last Updated: 14 Nov 2011

Go To URL
From interstitial cystitis to chronic pelvic pain.
 

Author(s): C Persu, V Cauni, S Gutue, Irina Blaj, V Jinga, P Geavlete

Journal: J Med Life. ;3(2):167-74.

 

There are still many things to be found out about interstitial cystitis/painful bladder syndrome (IC/PBS) because the pathological processes underlying the condition are not yet elucidated, biological markers of the condition are not yet available, and the type and severity of symptoms ...

Last Updated: 25 Oct 2010

Go To URL
 
 
Top

Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
Top

Clinical Trial Information This information is provided by ClinicalTrials.gov

Intranasal Oxytocin for the Treatment of Pain Associated With Interstitial Cystitis
 

Status: Recruiting

Condition Summary: Interstitial Cystitis

 

Last Updated: 6 Aug 2014

Go to URL

Last Updated: 4 Apr 2011

Go to URL
Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome
 

Status: Recruiting

Condition Summary: Interstitial Cystitis; Painful Bladder Syndrome

 

Last Updated: 23 Apr 2013

Go to URL