Inflammatory myofibroblastic tumor

Common Name(s)

Inflammatory myofibroblastic tumor

Inflammatory myofibroblastic tumor is made up of specific cells called myofibroblastic spindle cells. This tumor can occur in many different parts of the body, but it occurs most frequently in the lungs, soft tisues, or internal organs. Inflammatory myofibroblastic tumor usually develops in children or young adults, although it can affect people of any age. This type of tumor tends to recur in the same location, but it rarely spreads (metastasizes) to other parts of the body. Approximately 50% of inflammatory myofibroblastic tumors have rearrangements of the ALK gene on chromosome 2. Treatment typically involves surgery to remove the tumor.
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Inflammatory myofibroblastic tumor" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Inflammatory myofibroblastic tumor" returned 126 free, full-text research articles on human participants. First 3 results:

An inflammatory myofibroblastic tumor in the transplanted liver displaying quick wash-in and wash-out on contrast-enhanced ultrasound: A case report.
 

Author(s): Jing Shang, Yun-Yue Wang, Ying Dang, Xin-Juan Zhang, Yan Song, Li-Tao Ruan

Journal: Medicine (Baltimore). 2017 Dec;96(49):e9024.

 

Inflammatory myofibroblastic tumor (IMT) is an uncommon mesenchymal neoplasm, and its presence in a grafted liver is exceedingly rare.

Last Updated: 31 Dec 1969

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A case report of recurrent thyroid inflammatory myofibroblastic tumor and its metastasis in soft tissue.
 

Author(s): Jiajia Duan, Ying Wang

Journal: Medicine (Baltimore). 2017 Nov;96(45):e8485.

 

Inflammatory myofibroblastic tumor (IMT) is a neoplasm of low malignant potential. The most frequent site of IMT is in the lung, whereas recurrent and metastasis of thyroid IMT has been seldom reported.

Last Updated: 31 Dec 1969

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Imaging findings of inflammatory myofibroblastic tumor from the greater omentum: One case report.
 

Author(s): Wenjie Liang, Shengzhang Lin, Zhihua Chen

Journal: Medicine (Baltimore). 2017 Oct;96(41):e8297.

 

Inflammatory myofibroblastic tumors (IMTs) are rare neoplastic lesions with benign tendency. Even more rare are IMTs from the greater omentum (GO-IMT). A GO-IMT is easily misdiagnosed as other malignant tumors before operation; thus, clinicians need to be familiar with its imaging ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Inflammatory myofibroblastic tumor" returned 23 free, full-text review articles on human participants. First 3 results:

Uterine inflammatory myofibroblastic tumor: more common than expected: Case report and review.
 

Author(s): Vincenzo Dario Mandato, Riccardo Valli, Valentina Mastrofilippo, Alessandra Bisagni, Lorenzo Aguzzoli, Giovanni Battista La Sala

Journal: Medicine (Baltimore). 2017 Dec;96(48):e8974.

 

Inflammatory myofibroblastic tumor (IMT) is a rare mesenchymal neoplasm composed of spindled to epithelioid cells with prominent myxoid stroma and inflammatory infiltrate. It has a low but definite malignant potential. However, its management has never been standardized.

Last Updated: 31 Dec 1969

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Inflammatory myofibroblastic tumor of kidney together with ipsilateral perinephric and periureteric fibrosis: A case report and literature review.
 

Author(s): Zhuolun Sun, Hanbo Wang, Xudong Guo, Shaobo Jiang, Changying Jing

Journal: Medicine (Baltimore). 2017 Dec;96(49):e8807.

 

Both inflammatory myofibroblastic tumor (IMT) and retroperitoneal fibrosis are rare lesions, but kidney involvement is more rare. It is the first study about IMT of the kidney in a patient with perinephric and periureteric fibrosis and we hold that fibroblast proliferation may be ...

Last Updated: 31 Dec 1969

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Inflammatory myofibroblastic tumor of the lumbar spinal canal: A Case Report With Literature Review.
 

Author(s): Shanshan Wang, Liang Chen, Zhang Cao, Xijin Mao, Lin Zhang, Bin Wang

Journal: Medicine (Baltimore). 2017 Jun;96(26):e6488.

 

Inflammatory myofibroblastic tumor (IMT) is a rare type of mesenchymal tumor. IMT can arise in multiple anatomic locations. IMT of the lumbar spinal canal is exceptionally rare.

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery
 

Status: Recruiting

Condition Summary: Adult Fibrosarcoma; Alveolar Soft Part Sarcoma; Angiomatoid Fibrous Histiocytoma; Atypical Fibroxanthoma; Clear Cell Sarcoma of Soft Tissue; Epithelioid Malignant Peripheral Nerve Sheath Tumor; Epithelioid Sarcoma; Extraskeletal Myxoid Chondrosarcoma; Extraskeletal Osteosarcoma; Fibrohistiocytic Neoplasm; Glomus Tumor of the Skin; Inflammatory Myofibroblastic Tumor; Intimal Sarcoma; Leiomyosarcoma; Liposarcoma; Low Grade Fibromyxoid Sarcoma; Low Grade Myofibroblastic Sarcoma; Malignant Cutaneous Granular Cell Tumor; Malignant Peripheral Nerve Sheath Tumor; Malignant Triton Tumor; Mesenchymal Chondrosarcoma; Myxofibrosarcoma; Myxoid Chondrosarcoma; Myxoinflammatory Fibroblastic Sarcoma; Nerve Sheath Neoplasm; PEComa; Pericytic Neoplasm; Plexiform Fibrohistiocytic Tumor; Sclerosing Epithelioid Fibrosarcoma; Stage IB Soft Tissue Sarcoma AJCC v7; Stage IIB Soft Tissue Sarcoma AJCC v7; Stage III Soft Tissue Sarcoma AJCC v7; Stage IV Soft Tissue Sarcoma AJCC v7; Synovial Sarcoma; Undifferentiated (Embryonal) Sarcoma; Undifferentiated High Grade Pleomorphic Sarcoma of Bone

 

Last Updated: 15 Jan 2018

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Phase 1/2 Study of X-396, an Oral ALK Inhibitor, in Patients With ALK-positive Non-Small Cell Lung Cancer
 

Status: Recruiting

Condition Summary: Advanced Solid Tumors; Non-small Cell Lung Cancer

 

Last Updated: 29 Dec 2017

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Last Updated: 10 Nov 2017

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