Frontal fibrosing alopecia

Common Name(s)

Frontal fibrosing alopecia

Frontal fibrosing alopecia (FFA) is a form of lichen planus follicularis that is characterized primarily by slowly progressive hair loss (alopecia) and scarring on the scalp near the forehead. In some cases, the eyebrows, eye lashes and/or other parts of the body may be involved, as well. Although it has been suggested that FFA may be due to hormonal changes or an autoimmune response, the exact cause of this condition is not yet known. There is currently no cure for FFA; however, treatment with certain types of medications may stop or slow hair loss in some cases.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Frontal fibrosing alopecia" for support, advocacy or research.

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Cicatricial Alopecia Research Foundation

Cicatricial Alopecia Research Foundation (CARF) is a nonprofit public charities organization and the world's only voice for patients with cicatricial alopecia. MISSON: • Fund research to find effective treatments, and ultimately a cure • Support patient education and advocacy • Raise public awareness about the disease

Last Updated: 12 Sep 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Frontal fibrosing alopecia" for support, advocacy or research.

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Cicatricial Alopecia Research Foundation

Cicatricial Alopecia Research Foundation (CARF) is a nonprofit public charities organization and the world's only voice for patients with cicatricial alopecia. MISSON: • Fund research to find effective treatments, and ultimately a cure • Support patient education and advocacy • Raise public awareness about the disease

http://www.carfintl.org

Last Updated: 12 Sep 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Frontal fibrosing alopecia" returned 7 free, full-text research articles on human participants. First 3 results:

Frontal fibrosing alopecia in association with Sjögren's syndrome: more than a simple coincidence.
 

Author(s): Karina Colossi Furlan, Priscila Kakizaki, Juliana Cabral Nunes Chartuni, Neusa Yuriko Sakai Valente

Journal: An Bras Dermatol. ;91(5 suppl 1):14-16.

 

Frontal fibrosing alopecia is a distinctive form of scarring alopecia considered to be a clinical variant of lichen planopilaris. It predominantly occurs in postmenopausal women and has a slowly progressive course. It was first described by Kossard in 1994. Since then the number of ...

Last Updated: 16 Mar 2017

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Frontal Fibrosing Alopecia.
 

Author(s): S Holmes

Journal: Skin Therapy Lett.. 2016 Jul;21(4):5-7.

 

Frontal fibrosing alopecia, described just over 20 years ago, has become one of the most frequently seen causes of scarring alopecia at many specialist hair clinics. Considered a clinical variant of lichen planopilaris (LPP), it has distinctive features and associations which distinguish ...

Last Updated: 8 Jul 2016

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Frontal fibrosing alopecia and lichen planopilaris in HLA-identical mother and daughter.
 

Author(s): María Mercedes Otero Rivas, Sara Calleja Antolín, Pedro Sánchez Sambucety, Elia Samaniego González, José María García Ruíz de Morales, Manuel Ángel Rodríguez Prieto

Journal: Indian J Dermatol Venereol Leprol. ;81(2):162-5.

 

Frontal fibrosing alopecia (FFA) is a lymphocyte-mediated scarring alopecia thought to be a variant of lichen planopilaris (LPP). We present a 67-year-old woman with frontal fibrosing alopecia whose daughter was diagnosed to have lichen planopilaris. Both patients had identical human ...

Last Updated: 10 Mar 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Frontal fibrosing alopecia" returned 3 free, full-text review articles on human participants. First 3 results:

DHEA and frontal fibrosing alopecia: molecular and physiopathological mechanisms.
 

Author(s): Neide Kalil Gaspar

Journal: An Bras Dermatol. ;91(6):776-780.

 

The transforming growth factor-beta 1 (TGFβ1) promotes fibrosis, differentiating epithelial cells and quiescent fibroblasts into myofibroblasts and increasing expression of extracellular matrix. Recent investigations have shown that PPAR (peroxisome proliferator-activated receptor*) ...

Last Updated: 18 Jan 2017

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[Frontal fibrosing alopecia (FFA): Report on four cases and review of the literature].
 

Author(s): Miguel Ángel Cardona-Hernández, Fermín Jurado-Santa Cruz, Gisela Navarrete-Franco, Edna Azucena Gaxiola-Álvarez, Mónica Elizabeth de la Torre-García, Ana Luisa Cabrera-Pérez

Journal: Gac Med Mex. ;152(1):103-10.

 

Frontal fibrosing alopecia was recently described by Kossard, et al. as a progressive symmetrical recession of the frontal-temporal-parietal hairline affecting particularly postmenopausal women. Besides affecting the scalp, there are some cases in the literature with partial or total ...

Last Updated: 1 Mar 2016

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Frontal fibrosing alopecia: case report.
 

Author(s): Débora Nathália Smidarle, Mauren Seidl, Roberta Castilhos da Silva

Journal: An Bras Dermatol. ;85(6):879-82.

 

Frontal fibrosing alopecia is a kind of progressive and frequently irreversible cicatricial alopecia marked by a lichenoid infiltrate in histology. Since its first description, in 1994, in Australia, some cases have been documented all over the world. The article reports, for the ...

Last Updated: 10 Feb 2011

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Design and Validation of a New Assessment Tool for Lichen Planopilaris
 

Status: Recruiting

Condition Summary: Lichen Planopilaris of Scalp; Lichen Plano-Pilaris; Lichen Planopilaris; Frontal Fibrosing Alopecia

 

Last Updated: 13 Mar 2017

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