Fibromatosis

Common Name(s)

Fibromatosis

Fibromatosis refers to a group of conditions characterized by overgrowths of skin and connective tissue called fibromas. These fibromas are usually benign (non-cancerous). Fibromatosis can be classified by a person's age or by the location of the fibromas. The cause of fibromatosis is often unknown, and treatment depends on the individual disease.
 

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Fibromatosis" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Fibromatosis" returned 140 free, full-text research articles on human participants. First 3 results:

Targeting stem cell behavior in desmoid tumors (aggressive fibromatosis) by inhibiting hedgehog signaling.
 

Author(s): Ronak Ghanbari-Azarnier, Shingo Sato, Qingxia Wei, Mushriq Al-Jazrawe, Benjamin A Alman

Journal: Neoplasia. 2013 Jul;15(7):712-9.

 

Desmoid tumor (also called aggressive fibromatosis) is a lesion of mesenchymal origin that can occur as a sporadic tumor or a manifestation of the preneoplastic syndrome, familial adenomatous polyposis caused by a mutation in adenomatous polyposis coli (APC). This tumor type is characterized ...

Last Updated: 1 Jul 2013

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A prognostic nomogram for prediction of recurrence in desmoid fibromatosis.
 

Author(s): Aimeé M Crago, Brian Denton, Sébastien Salas, Armelle Dufresne, James J Mezhir, Meera Hameed, Mithat Gonen, Samuel Singer, Murray F Brennan

Journal: Ann. Surg.. 2013 Aug;258(2):347-53.

 

To construct a postoperative nomogram to estimate the risk of local recurrence for patients with desmoid tumors.

Last Updated: 10 Jul 2013

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Variable Ki67 proliferative index in 65 cases of nodular fasciitis, compared with fibrosarcoma and fibromatosis.
 

Author(s): Xu-Yong Lin, Liang Wang, Yong Zhang, Shun-Dong Dai, En-Hua Wang

Journal:

 

Nodular fasciitis is the most common pseudosarcomatous lesion of soft tissue. Ki67 was considered as a useful marker for distinguishing some benign and malignant lesions. To study the usefulness of Ki67 in diagnosis of nodular fasciitis, the expression of Ki67 was examined by using ...

Last Updated: 11 Apr 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Fibromatosis" returned 13 free, full-text review articles on human participants. First 3 results:

Desmoid type fibromatosis in the facet joint of lumbar spine: case report and review of literature.
 

Author(s): So Jung Kim, Doo Hoe Ha, Sang Min Lee, Haeyoun Kang

Journal: Korean J Radiol. ;14(5):818-22.

 

Desmoid type fibromatosis is a benign fibroblastic tumor arising from the fascia or musculoaponeurosis. It may occur in various locations, but most commonly in the shoulder girdle and neck; to our knowledge, there has been no reported case originating from a facet joint of the spine. ...

Last Updated: 17 Sep 2013

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Gingival fibromatosis with multiple unusual findings: report of a rare case.
 

Author(s): Long He, Fei-Yun Ping

Journal: Int J Oral Sci. 2012 Dec;4(4):221-5.

 

Gingival fibromatosis is a rare disease, especially its syndromic form. Here, we review the literatures on gingival fibromatosis and briefly summarize some characters on clinical, etiological, genetic and histopathological aspects. We also present a rare case of gingival fibromatosis ...

Last Updated: 11 Jan 2013

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Juvenile hyaline fibromatosis: a case report and review of literature.
 

Author(s): Sandra Lúcia Ribeiro, Erilane L Guedes, Valeria Botan, Alessandra Barbosa, Ernani J Freitas

Journal: Acta Reumatol Port. ;34(1):128-33.

 

Juvenile hyaline fibromatosis (JHF) is a rare disease with autosomal recessive inheritance that occurs mainly in childhood and is characterized by the deposition of amorphous hyaline material in the skin and other organs. There are approximately 70 cases reported in the literature. ...

Last Updated: 14 Apr 2009

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults With Desmoid Tumors/Aggressive Fibromatosis
 

Status: Recruiting

Condition Summary: Desmoid Tumors; Aggressive Fibromatosis

 

Last Updated: 14 Mar 2014

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Peripheral Primitive Fibromatosis
 

Status: Recruiting

Condition Summary: Peripheral Primitive Fibromatosis

 

Last Updated: 27 Feb 2013

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Last Updated: 13 Feb 2014

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