Duane syndrome

Common Name(s)

Duane syndrome

Duane syndrome is a disorder of eye movement. This condition prevents outward movement of the eye (toward the ear), and in some cases may also limit inward eye movement (toward the nose). As the eye moves inward, the eyelids partially close and the eyeball pulls back (retracts) into its socket. Usually only one eye is affected. Some people with Duane syndrome develop amblyopia ("lazy eye"), a condition that causes vision loss in the affected eye. Most cases occur without other signs and symptoms. There are three forms of Duane syndrome, designated types 1, 2, and 3. The types vary in which eye movements are most severely restricted (inward, outward, or both). All three types are characterized by retraction of the eyeball as the eye moves inward and are inherited in an autosomal dominant fashion.  
 

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Duane syndrome" for support, advocacy or research.

There are currently no organizations listed in Disease InfoSearch that support this condition. Create a listing.

 

 

General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Duane syndrome" returned 28 free, full-text research articles on human participants. First 3 results:

Diversified clinical presentations associated with a novel sal-like 4 gene mutation in a Chinese pedigree with Duane retraction syndrome.
 

Author(s): Ming-ming Yang, Mary Ho, Henry H W Lau, Pancy O S Tam, Alvin L Young, Chi Pui Pang, Wilson W K Yip, LiJia Chen

Journal:

 

To determine the underlying genetic cause of Duane retraction syndrome (DRS) in a non-consanguineous Chinese Han family.

Last Updated: 20 May 2013

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Vertical deviation and A pattern of type III Duane retraction syndrome.
 

Author(s): Hai-Cheng She, Feng-Yuan Man, Zhen-Chang Wang, Jing-Hui Wang, Yong-Hong Jiao, Kan-Xing Zhao

Journal: Chin. Med. J.. 2012 Aug;125(16):2929-32.

 

Researches in ocular electromyography (EMG) and Magnetic resonance imaging (MRI) of patients with Duane retraction syndrome (DRS) suggest that there may be additional abnormalities such as paradoxical innervation between horizontal rectus muscles and vertical rectus muscles, hypoplasia ...

Last Updated: 30 Aug 2012

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Isolated y-splitting and recession of the lateral rectus muscle in patients with exo-duane syndrome.
 

Author(s): Federico G Velez, Guillermo Velez, Karen Hendler, Stacy L Pineles

Journal: Strabismus. 2012 Sep;20(3):109-14.

 

Weakening of both horizontal rectus muscles is performed for patients with Duane syndrome and significant misinnervation of the lateral rectus (LR) muscle resulting in strabismus, limitation to ocular rotations, and globe retraction. In patients with severe up-/downshoots, a Y-splitting ...

Last Updated: 21 Aug 2012

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Duane syndrome" returned 1 free, full-text review articles on human participants. First 3 results:

Review of the major findings about Duane retraction syndrome (DRS) leading to an updated form of classification.
 

Author(s): Demet Yüksel, Jean-Jacques Orban de Xivry, Philippe Lefèvre

Journal: Vision Res.. 2010 Nov;50(23):2334-47.

 

In view of all the reported evidence by electromyography in the 1970s, by histology in the 1980s, and by cerebral imagery since the 2000s, Duane retraction syndrome (DRS) has been described as the consequence of a congenital anomaly of the 6th cranial nerve nuclei with aberrant innervations ...

Last Updated: 8 Nov 2010

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Symptoms, Diagnosis, and Treatment

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