Complex regional pain syndrome

Common Name(s)

Complex regional pain syndrome

Complex regional pain syndrome (CRPS) is a chronic pain condition that mainly affects the arm or leg after an injury. The main feature of CRPS is continuous, intense pain that is out of proportion to the severity of the injury. The pain gets worse over time and often spreads throughout the entire affected arm or leg.  Other symptoms may include color and temperature changes of the skin over the affected area; skin sensitivity; sweating; and swelling. The underlying cause of CRPS is not known. Treatment aims to relieve pain and may include topical or oral medications; physical therapy; and/or a sympathetic nerve block.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Complex regional pain syndrome" for support, advocacy or research.

US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Complex regional pain syndrome" for support, advocacy or research.

US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Complex regional pain syndrome" returned 214 free, full-text research articles on human participants. First 3 results:

Hsa-miR-34a mediated repression of corticotrophin releasing hormone receptor 1 regulates pro-opiomelanocortin expression in patients with complex regional pain syndrome.
 

Author(s): Botros B Shenoda, Guillermo M Alexander, Seena K Ajit

Journal:

 

Ketamine provides relief for a subset of patients with complex regional pain syndrome (CRPS). The poor responders had a lower body mass index (BMI) relative to responders. Regulation of proopiomelanocortin (POMC) expression is crucial in normal body weight homeostasis. The main objectives ...

Last Updated: 4 Mar 2016

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HPV Vaccination and Complex Regional Pain Syndrome: Lack of Evidence.
 

Author(s): Cindy M Weinbaum, Maria Cano

Journal:

 

Last Updated: 18 Jan 2016

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Complex Regional Pain Syndrome-Type 1 Presenting as deQuervain's Stenosing Tenosynovitis.
 

Author(s): Lakshmi Vas, Renuka Pai

Journal: Pain Physician. 2016 Jan;19(1):E227-34.

 

To report the presentation of complex regional pain syndrome-1 (CRPS-1) as deQuervain's stenosing tenosynovitis (DQST).

Last Updated: 12 Jan 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Complex regional pain syndrome" returned 35 free, full-text review articles on human participants. First 3 results:

Invasive Management for Pediatric Complex Regional Pain Syndrome: Literature Review of Evidence.
 

Author(s): Manuel J Rodriguez, Mariano Fernandez-Baena, Alex Barroso, Jose A Yanez

Journal: Pain Physician. 2015 Nov;18(6):621-30.

 

Complex regional pain syndrome (CRPS) is a multifactorial condition with complex pathogenesis characterized by spontaneous or stimulus-induced pain that is disproportionate to the inciting event. It is also commonly accompanied by a myriad of autonomic and motor disturbances in highly ...

Last Updated: 26 Nov 2015

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Complex regional pain syndrome.
 

Author(s): Stephen Bruehl

Journal:

 

Complex regional pain syndrome is a chronic pain condition characterized by autonomic and inflammatory features. It occurs acutely in about 7% of patients who have limb fractures, limb surgery, or other injuries. Many cases resolve within the first year, with a smaller subset progressing ...

Last Updated: 30 Jul 2015

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Complex regional pain syndrome and acute carpal tunnel syndrome following radial artery cannulation: a neurological perspective and review of the literature.
 

Author(s): Reynaldo P Lazaro

Journal: Medicine (Baltimore). 2015 Jan;94(3):e422.

 

Complex regional pain syndrome (CRPS) associated with acute carpal tunnel syndrome (aCTS) developed in a 38-year-old right-handed man following radial artery cannulation (RAC) during the course of lumbar spine surgery. Inciting events and risk factors that might have led to these ...

Last Updated: 27 Jan 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Body Perception and Complex Regional Pain Syndrome
 

Status: Recruiting

Condition Summary: Complex Regional Pain Syndromes

 

Last Updated: 3 Oct 2016

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Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome
 

Status: Recruiting

Condition Summary: Complex Regional Pain Syndrome

 

Last Updated: 28 Apr 2016

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Role of Vitamin C at 6 Months on Incidence of Complex Regional Pain Syndrome Type I in Upper Limb Surgery
 

Status: Recruiting

Condition Summary: Complex Regional Pain Syndrome (CRPS) TYPE I

 

Last Updated: 3 Aug 2016

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