Cluster headache

Common Name(s)

Cluster headache

Cluster headaches are a form of headache notable for their extreme pain and their pattern of occurring in "clusters", usually at the same time(s) of the day for several weeks.   A cluster headache usually begins suddenly with excruciating pain on one side of the head, often behind or around one eye.  In some individuals, it may be preceded by a migraine-like "aura." The pain usually peaks over the next 5 to 10 minutes, and then continues at that intensity for up to an hour or two before going away. Cluster headaches generally begin between the ages of 20 and 50, although the syndrome can also start in childhood or late in life. Males are much more likely than females to develop cluster headaches.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cluster headache" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cluster headache" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cluster headache" returned 131 free, full-text research articles on human participants. First 3 results:

Cost-effectiveness of stimulation of the sphenopalatine ganglion (SPG) for the treatment of chronic cluster headache: a model-based analysis based on the Pathway CH-1 study.
 

Author(s): Jan B Pietzsch, Abigail Garner, Charly Gaul, Arne May

Journal: J Headache Pain. 2015 ;16():530.

 

In the recent Pathway CH-1 study, on-demand stimulation of the sphenopalatine ganglion (SPG) by means of an implantable neurostimulation system was proven to be a safe and effective therapy for the treatment of chronic cluster headache. Our objective was to assess the cost-effectiveness ...

Last Updated: 25 May 2015

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The neuropsychology of cluster headache: cognition, mood, disability, and quality of life of patients with chronic and episodic cluster headache.
 

Author(s): Mariam Torkamani, Lea Ernst, Lok Sze Cheung, Giorgio Lambru, Manjit Matharu, Marjan Jahanshahi

Journal: Headache. 2015 Feb;55(2):287-300.

 

Cluster headache (CH) is commonly regarded as one of the most disabling headache conditions, and referred to as one of the most painful conditions known to humankind. Although there has been some research indicating the severe impact of CH, there is little comprehensive evidence of ...

Last Updated: 18 Feb 2015

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Cluster-like headache as presenting feature of Vogt-Koyanagi-Harada disease.
 

Author(s): Vikas Kanaujia, Vimal K Paliwal, A Aneez, Rachna Agarwal

Journal: Neurol India. ;62(6):681-3.

 

Last Updated: 16 Jan 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cluster headache" returned 22 free, full-text review articles on human participants. First 3 results:

Cluster headache.
 

Author(s): Jacqueline Weaver-Agostoni

Journal: Am Fam Physician. 2013 Jul;88(2):122-8.

 

Cluster headache causes severe unilateral temporal or periorbital pain, lasting 15 to 180 minutes and accompanied by autonomic symptoms in the nose, eyes, and face. Headaches often recur at the same time each day during the cluster period, which can last for weeks to months. Some ...

Last Updated: 13 Aug 2013

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Neuroimaging in cluster headache and other trigeminal autonomic cephalalgias.
 

Author(s): Elisa Iacovelli, Gianluca Coppola, Emanuele Tinelli, Francesco Pierelli, Federico Bianco

Journal: J Headache Pain. 2012 Jan;13(1):11-20.

 

The central nervous system mechanisms involved in trigeminal autonomic cephalalgias, a group of primary headaches characterized by strictly unilateral head pain that occurs in association with ipsilateral craniofacial autonomic features, are still not comprehensively understood. However, ...

Last Updated: 9 Jan 2012

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[Review of the target for the deep brain stimulation of chronic cluster headache].
 

Author(s): F Seijo-Fernandez, E Seijo-Zazo, A Saiz-Ayala, E Santamarta-Liebana, M A Alvarez-Vega, B Lozano-Aragoneses, J Sol, F Fernandez-Gonzalez

Journal: Rev Neurol. 2011 Mar;52(6):366-70.

 

Cluster headache is included in the group of trigeminal autonomic cephalalgias. Although the pathophysiology of cluster headache has not yet been sufficiently established, the theory of a central origin tells us that this headache is produced by hypothalamic dysfunction. More than ...

Last Updated: 9 Mar 2011

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Symptoms, Diagnosis, and Treatment

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Sumatriptan 4 mg Statdose in the Acute Treatment of Cluster Headache
 

Status: Recruiting

Condition Summary: Episodic Cluster Headache; Chronic Cluster Headache

 

Last Updated: 29 Jan 2009

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The Efficacy of L-cysteine in Prevention of Cluster Headache
 

Status: Recruiting

Condition Summary: Cluster Headache

 

Last Updated: 20 Jan 2016

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Sleep, Circadian Rhythms and Cluster Headache
 

Status: Recruiting

Condition Summary: Cluster Headache

 

Last Updated: 1 Dec 2015

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