Cluster headache

Common Name(s)

Cluster headache

Cluster headaches are a form of headache notable for their extreme pain and their pattern of occurring in "clusters", usually at the same time(s) of the day for several weeks.   A cluster headache usually begins suddenly with excruciating pain on one side of the head, often behind or around one eye.  In some individuals, it may be preceded by a migraine-like "aura." The pain usually peaks over the next 5 to 10 minutes, and then continues at that intensity for up to an hour or two before going away. Cluster headaches generally begin between the ages of 20 and 50, although the syndrome can also start in childhood or late in life. Males are much more likely than females to develop cluster headaches.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cluster headache" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cluster headache" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cluster headache" returned 163 free, full-text research articles on human participants. First 3 results:

Optimal deep brain stimulation site and target connectivity for chronic cluster headache.
 

Author(s): Harith Akram, Sarah Miller, Susie Lagrata, Marwan Hariz, John Ashburner, Tim Behrens, Manjit Matharu, Ludvic Zrinzo

Journal: Neurology. 2017 Nov;89(20):2083-2091.

 

To investigate the mechanism of action of deep brain stimulation for refractory chronic cluster headache and the optimal target within the ventral tegmental area.

Last Updated: 31 Dec 1969

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Clomiphene treatment may be effective in refractory episodic and chronic cluster headache.
 

Author(s): Maria Eduarda Nobre, Mario Fernando Prieto Peres, Pedro Ferreira Moreira, Antonio José Leal

Journal: Arq Neuropsiquiatr. 2017 Sep;75(9):620-624.

 

To describe the evolution of 15 patients who were treated for difficult-to-control episodic and chronic cluster headaches with clomiphene.

Last Updated: 31 Dec 1969

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Naratriptan May Become an Alternative Prophylactic Option for Patients with Cluster Headache.
 

Author(s): Shoji Kikui, Takao Takeshima

Journal: Intern. Med.. 2017 10;56(19):2547-2548.

 

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cluster headache" returned 29 free, full-text review articles on human participants. First 3 results:

The development and validation of the Cluster Headache Quality of life scale (CHQ).
 

Author(s): Norazah Abu Bakar, Mariam Torkamani, Surat Tanprawate, Giorgio Lambru, Manjit Matharu, Marjan Jahanshahi

Journal: J Headache Pain. 2016 Dec;17(1):79.

 

Cluster headache (CH) is a rare, excruciating and highly disabling primary headache disorder. Using non cluster headache specific measures, previous studies have shown that CH has a significant negative impact on patients' quality of life (QoL), but a CH-specific QoL scale is currently ...

Last Updated: 31 Dec 1969

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[Cluster headache in pediatric population: four case reports and review of the literature].
 

Author(s): C Alfaro-Iznaola, D Natera-de Benito, R Rodriguez-Diaz, M A Taboas-Pereira, M Cuadrado-Martin, M M Ballesteros-Garcia

Journal: Rev Neurol. 2016 Jul;63(2):65-70.

 

Cluster headache is a rare cause of primary headache in children. We report four cases with a mean age of onset of 8.6, ranged from 2 to 13 years.

Last Updated: 31 Dec 1969

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The Neuropharmacology of Cluster Headache and other Trigeminal Autonomic Cephalalgias.
 

Author(s): Alfredo Costa, Fabio Antonaci, Matteo Cotta Ramusino, Giuseppe Nappi

Journal: Curr Neuropharmacol. 2015 ;13(3):304-23.

 

Trigeminal autonomic cephalalgias (TACs) are a group of primary headaches including cluster headache (CH), paroxysmal hemicrania (PH) and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT). Another form, hemicrania continua (HC), is also ...

Last Updated: 31 Dec 1969

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Clinical Trial Information This information is provided by ClinicalTrials.gov

The Efficacy of L-cysteine in Prevention of Cluster Headache
 

Status: Recruiting

Condition Summary: Cluster Headache

 

Last Updated: 22 Jun 2017

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Safety and Efficacy Study of SOM230 s.c. in Cluster Headache
 

Status: Recruiting

Condition Summary: Cluster Headache - Episodic and Chronic

 

Last Updated: 5 Feb 2018

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Botulinum Toxin Type A Block of the Otic Ganglion in Chronic Cluster Headache: Safety Issues
 

Status: Recruiting

Condition Summary: Cluster Headache

 

Last Updated: 5 Apr 2018

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