Cluster headache

Common Name(s)

Cluster headache

Cluster headaches are a form of headache notable for their extreme pain and their pattern of occurring in "clusters", usually at the same time(s) of the day for several weeks.   A cluster headache usually begins suddenly with excruciating pain on one side of the head, often behind or around one eye.  In some individuals, it may be preceded by a migraine-like "aura." The pain usually peaks over the next 5 to 10 minutes, and then continues at that intensity for up to an hour or two before going away. Cluster headaches generally begin between the ages of 20 and 50, although the syndrome can also start in childhood or late in life. Males are much more likely than females to develop cluster headaches.  
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cluster headache" for support, advocacy or research.

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National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

Last Updated: 16 Mar 2015

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cluster headache" for support, advocacy or research.

Logo
National Headache Foundation

The National Headache Foundation exists to enhance the healthcare of individuals with headache. It is a source of help to their families, physicians and allied healthcare professionals who treat them, and to the public. The NHF accomplishes its mission by providing educational and informational resources, supporting headache research, and advocating for the understanding of headache as a legitimate neurobiological disease.

http://www.headaches.org

Last Updated: 16 Mar 2015

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cluster headache" returned 153 free, full-text research articles on human participants. First 3 results:

Effects of non-invasive vagus nerve stimulation on attack frequency over time and expanded response rates in patients with chronic cluster headache: a post hoc analysis of the randomised, controlled PREVA study.
 

Author(s): Charly Gaul, Delphine Magis, Eric Liebler, Andreas Straube

Journal: J Headache Pain. 2017 Dec;18(1):22.

 

In the PREVention and Acute treatment of chronic cluster headache (PREVA) study, attack frequency reductions from baseline were significantly more pronounced with non-invasive vagus nerve stimulation plus standard of care (nVNS + SoC) than with SoC alone. Given the intensely painful ...

Last Updated: 15 Feb 2017

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Clinical Features of Cluster Headache Patients in Korea.
 

Author(s): Heui Soo Moon, Jeong Wook Park, Kwang Soo Lee, Chin Sang Chung, Byung Kun Kim, Jae Moon Kim, Jong Hee Sohn, Min Kyung Chu, Kyungmi Oh, Soo Jin Cho

Journal: J. Korean Med. Sci.. 2017 Mar;32(3):502-506.

 

Cluster headache (CH) is a rare underdiagnosed primary headache disorder with very severe unilateral pain and autonomic symptoms. Clinical characteristics of Korean patients with CH have not yet been reported. We analyzed the clinical features of CH patients from 11 university hospitals ...

Last Updated: 1 Feb 2017

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A genome-wide analysis in cluster headache points to neprilysin and PACAP receptor gene variants.
 

Author(s): Elena Bacchelli, Maria Michela Cainazzo, Cinzia Cameli, Simona Guerzoni, Angela Martinelli, Michele Zoli, Elena Maestrini, Luigi Alberto Pini

Journal: J Headache Pain. 2016 Dec;17(1):114.

 

Cluster Headache (CH) is a severe primary headache, with a poorly understood pathophysiology. Complex genetic factors are likely to play a role in CH etiology; however, no confirmed gene associations have been identified. The aim of this study is to identify genetic variants influencing ...

Last Updated: 13 Dec 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cluster headache" returned 27 free, full-text review articles on human participants. First 3 results:

The development and validation of the Cluster Headache Quality of life scale (CHQ).
 

Author(s): Norazah Abu Bakar, Mariam Torkamani, Surat Tanprawate, Giorgio Lambru, Manjit Matharu, Marjan Jahanshahi

Journal: J Headache Pain. 2016 Dec;17(1):79.

 

Cluster headache (CH) is a rare, excruciating and highly disabling primary headache disorder. Using non cluster headache specific measures, previous studies have shown that CH has a significant negative impact on patients' quality of life (QoL), but a CH-specific QoL scale is currently ...

Last Updated: 6 Sep 2016

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The Neuropharmacology of Cluster Headache and other Trigeminal Autonomic Cephalalgias.
 

Author(s): Alfredo Costa, Fabio Antonaci, Matteo Cotta Ramusino, Giuseppe Nappi

Journal: Curr Neuropharmacol. 2015 ;13(3):304-23.

 

Trigeminal autonomic cephalalgias (TACs) are a group of primary headaches including cluster headache (CH), paroxysmal hemicrania (PH) and short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT). Another form, hemicrania continua (HC), is also ...

Last Updated: 28 Sep 2015

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Cluster headache.
 

Author(s): Karl B Alstadhaug, Hilde Karen Ofte

Journal:

 

Last Updated: 28 Aug 2015

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 2 Aug 2016

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The Efficacy of L-cysteine in Prevention of Cluster Headache
 

Status: Recruiting

Condition Summary: Cluster Headache

 

Last Updated: 22 Jun 2017

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Cluster Headache, Addictions and Vascular Function
 

Status: Recruiting

Condition Summary: Cluster Headache

 

Last Updated: 21 Dec 2015

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