Chronic fatigue syndrome

Common Name(s)

Chronic fatigue syndrome

Chronic fatigue syndrome is a condition that causes extreme, long-lasting fatigue which can limit the ability to participate in ordinary, daily activities. It generally occurs in young adults between the ages of 20 and 40. The main symptom of this condition is disabling fatigue that does not improve with rest. Other signs and symptoms may include muscle pain; joint pain; concentration and memory problems; headaches; sleep problems; fever; sore throat; and/or tender lymph nodes. The exact cause of chronic fatigue syndrome is not known, but it has been proposed that infectious agents, immune system impairment and/or hormonal system deregulation may be involved. There is no cure for this condition; the goal of treatment is to improve symptoms. Medications may be used to treat pain, sleep disorders and other associated problems.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

Last Updated: 15 Aug 2014

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Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

http://solvecfs.org/

Last Updated: 15 Aug 2014

View Details
Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

http://www.wicfs-me.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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General Resources

SolveCFS BioBank

The SolveCFS BioBank collects and stores a bank of biological samples and clinical information from individuals with CFS and unaffected individuals aged 10 and older.

Updated 6 Dec 2012

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Research1st News

Our free monthly e-newsletter, Research1st News, provides the latest research and policy news, as well as information about upcoming events and media coverage. Visit the archive to read past issues and to sign up to receive upcoming issues by email.

Updated 6 Dec 2012

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SolveCFS: The Chronicle of the CFIDS Association of America

The Association's print publication highlighting how the Association is advancing progress in CFS research and policy and it will share global news of interest to those who are committed to our cause.

Updated 6 Dec 2012

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ME.CFS. Toll free hotline.

Agencies can e mail us to ask for posters to display our hotline number so clients can attain disease information. IMPORTANT TO NOT discard those without computers.

Updated 1 Feb 2013

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Blogs

Research1st

This website is intended to become a one-stop shop for the most current and reliable information about CFS-related research being conducted by top-flight scientists worldwide.

Updated 6 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic fatigue syndrome" returned 694 free, full-text research articles on human participants. First 3 results:

Cellular bioenergetics is impaired in patients with chronic fatigue syndrome.
 

Author(s): Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning

Journal:

 

Chronic fatigue syndrome (CFS) is a highly debilitating disease of unknown aetiology. Abnormalities in bioenergetic function have been cited as one possible cause for CFS. Preliminary studies were performed to investigate cellular bioenergetic abnormalities in CFS patients. A series ...

Last Updated: 24 Oct 2017

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Are current chronic fatigue syndrome criteria diagnosing different disease phenotypes?
 

Author(s): Laura Maclachlan, Stuart Watson, Peter Gallagher, Andreas Finkelmeyer, Leonard A Jason, Madison Sunnquist, Julia L Newton

Journal:

 

Chronic fatigue syndrome (CFS) is characterised by a constellation of symptoms diagnosed with a number of different polythetic criteria. Heterogeneity across these diagnostic criteria is likely to be confounding research into the as-yet-unknown pathophysiology underlying this stigmatised ...

Last Updated: 20 Oct 2017

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Altered right anterior insular connectivity and loss of associated functions in adolescent chronic fatigue syndrome.
 

Author(s): Laura Anne Wortinger, Merete Glenne Øie, Tor Endestad, Vegard Bruun Wyller

Journal:

 

Impairments in cognition, pain intolerance, and physical inactivity characterize adolescent chronic fatigue syndrome (CFS), yet little is known about its neurobiology. The right dorsal anterior insular (dAI) connectivity of the salience network provides a motivational context to stimuli. ...

Last Updated: 7 Sep 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic fatigue syndrome" returned 63 free, full-text review articles on human participants. First 3 results:

Vitamin and mineral status in chronic fatigue syndrome and fibromyalgia syndrome: A systematic review and meta-analysis.
 

Author(s): Monica L Joustra, Isidor Minovic, Karin A M Janssens, Stephan J L Bakker, Judith G M Rosmalen

Journal:

 

Many chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS) patients (35-68%) use nutritional supplements, while it is unclear whether deficiencies in vitamins and minerals contribute to symptoms in these patients. Objectives were (1) to determine vitamin and mineral status ...

Last Updated: 28 Apr 2017

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Acupuncture and moxibustion for chronic fatigue syndrome in traditional Chinese medicine: a systematic review and meta-analysis.
 

Author(s): Taiwu Wang, Cong Xu, Keli Pan, Hongyan Xiong

Journal:

 

As the etiology of chronic fatigue syndrome (CFS) is unclear and the treatment is still a big issue. There exists a wide range of literature about acupuncture and moxibustion (AM) for CFS in traditional Chinese medicine (TCM). But there are certain doubts as well in the effectiveness ...

Last Updated: 24 Mar 2017

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Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).
 

Author(s): William M Mitchell

Journal: Expert Rev Clin Pharmacol. 2016 Jun;9(6):755-70.

 

Chronic fatigue syndrome/ Myalgic encephalomyelitis (CFS/ME) is a poorly understood seriously debilitating disorder in which disabling fatigue is an universal symptom in combination with a variety of variable symptoms. The only drug in advanced clinical development is rintatolimod, ...

Last Updated: 25 May 2016

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Noradrenergic and Stress-Related Etiologies of Chronic Fatigue Syndrome
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 6 Mar 2017

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High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome
 

Status: Not yet recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 3 Oct 2016

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Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 18 Oct 2017

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