Chronic fatigue syndrome

Common Name(s)

Chronic fatigue syndrome

Chronic fatigue syndrome is a condition that causes extreme, long-lasting fatigue which can limit the ability to participate in ordinary, daily activities. It generally occurs in young adults between the ages of 20 and 40. The main symptom of this condition is disabling fatigue that does not improve with rest. Other signs and symptoms may include muscle pain; joint pain; concentration and memory problems; headaches; sleep problems; fever; sore throat; and/or tender lymph nodes. The exact cause of chronic fatigue syndrome is not known, but it has been proposed that infectious agents, immune system impairment and/or hormonal system deregulation may be involved. There is no cure for this condition; the goal of treatment is to improve symptoms. Medications may be used to treat pain, sleep disorders and other associated problems.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

Last Updated: 15 Aug 2014

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Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

http://solvecfs.org/

Last Updated: 15 Aug 2014

View Details
Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

http://www.wicfs-me.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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General Resources

SolveCFS BioBank

The SolveCFS BioBank collects and stores a bank of biological samples and clinical information from individuals with CFS and unaffected individuals aged 10 and older.

Updated 6 Dec 2012

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Research1st News

Our free monthly e-newsletter, Research1st News, provides the latest research and policy news, as well as information about upcoming events and media coverage. Visit the archive to read past issues and to sign up to receive upcoming issues by email.

Updated 6 Dec 2012

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SolveCFS: The Chronicle of the CFIDS Association of America

The Association's print publication highlighting how the Association is advancing progress in CFS research and policy and it will share global news of interest to those who are committed to our cause.

Updated 6 Dec 2012

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ME.CFS. Toll free hotline.

Agencies can e mail us to ask for posters to display our hotline number so clients can attain disease information. IMPORTANT TO NOT discard those without computers.

Updated 1 Feb 2013

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Blogs

Research1st

This website is intended to become a one-stop shop for the most current and reliable information about CFS-related research being conducted by top-flight scientists worldwide.

Updated 6 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic fatigue syndrome" returned 654 free, full-text research articles on human participants. First 3 results:

Detection of Urine Metabolites in a Rat Model of Chronic Fatigue Syndrome before and after Exercise.
 

Author(s): Changzhuan Shao, Yiming Ren, Zinan Wang, Chenzhe Kang, Hongke Jiang, Aiping Chi

Journal: Biomed Res Int. 2017 ;2017():8182020.

 

Purpose. The aim of the present study was to elucidate the metabolic mechanisms associated with chronic fatigue syndrome (CFS) via an analysis of urine metabolites prior to and following exercise in a rat model. Methods. A rat model of CFS was established using restraint-stress, forced ...

Last Updated: 19 Apr 2017

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Clinically proven mtDNA mutations are not common in those with chronic fatigue syndrome.
 

Author(s): Elizna M Schoeman, Francois H Van Der Westhuizen, Elardus Erasmus, Etresia van Dyk, Charlotte V Y Knowles, Shereen Al-Ali, Wan-Fai Ng, Robert W Taylor, Julia L Newton, Joanna L Elson

Journal:

 

Chronic Fatigue Syndrome (CFS) is a prevalent debilitating condition that affects approximately 250,000 people in the UK. There is growing interest in the role of mitochondrial function and mitochondrial DNA (mtDNA) variation in CFS. It is now known that fatigue is common and often ...

Last Updated: 17 Mar 2017

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Patterns of control beliefs in chronic fatigue syndrome: results of a population-based survey.
 

Author(s): Johanna M Doerr, Daniela S Jopp, Michael Chajewski, Urs M Nater

Journal:

 

Chronic fatigue syndrome (CFS) represents a unique clinical challenge for patients and health care providers due to unclear etiology and lack of specific treatment. Characteristic patterns of behavior and cognitions might be related to how CFS patients respond to management strategies.

Last Updated: 7 Mar 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic fatigue syndrome" returned 61 free, full-text review articles on human participants. First 3 results:

Acupuncture and moxibustion for chronic fatigue syndrome in traditional Chinese medicine: a systematic review and meta-analysis.
 

Author(s): Taiwu Wang, Cong Xu, Keli Pan, Hongyan Xiong

Journal:

 

As the etiology of chronic fatigue syndrome (CFS) is unclear and the treatment is still a big issue. There exists a wide range of literature about acupuncture and moxibustion (AM) for CFS in traditional Chinese medicine (TCM). But there are certain doubts as well in the effectiveness ...

Last Updated: 24 Mar 2017

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Efficacy of rintatolimod in the treatment of chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME).
 

Author(s): William M Mitchell

Journal: Expert Rev Clin Pharmacol. 2016 Jun;9(6):755-70.

 

Chronic fatigue syndrome/ Myalgic encephalomyelitis (CFS/ME) is a poorly understood seriously debilitating disorder in which disabling fatigue is an universal symptom in combination with a variety of variable symptoms. The only drug in advanced clinical development is rintatolimod, ...

Last Updated: 25 May 2016

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Sleep Disturbances in Pediatric Chronic Fatigue Syndrome: A Review of Current Research.
 

Author(s): Kelli Snodgrass, Adrienne Harvey, Adam Scheinberg, Sarah Knight

Journal:

 

Children and adolescents with chronic fatigue syndrome (CFS) frequently report sleep disturbances. However, little is known about the nature and severity of sleep disturbance and factors associated with sleep problems in pediatric CFS. The purpose of this review was to synthesize ...

Last Updated: 28 Aug 2015

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Noradrenergic and Stress-Related Etiologies of Chronic Fatigue Syndrome
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 6 Mar 2017

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High-tech Acupuncture for Treatment of Chronic Fatigue Syndrome
 

Status: Not yet recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 3 Oct 2016

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Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 21 Apr 2017

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