Chronic fatigue syndrome

Common Name(s)

Chronic fatigue syndrome

Chronic fatigue syndrome is a condition that causes extreme, long-lasting fatigue which can limit the ability to participate in ordinary, daily activities. It generally occurs in young adults between the ages of 20 and 40. The main symptom of this condition is disabling fatigue that does not improve with rest. Other signs and symptoms may include muscle pain; joint pain; concentration and memory problems; headaches; sleep problems; fever; sore throat; and/or tender lymph nodes. The exact cause of chronic fatigue syndrome is not known, but it has been proposed that infectious agents, immune system impairment and/or hormonal system deregulation may be involved. There is no cure for this condition; the goal of treatment is to improve symptoms. Medications may be used to treat pain, sleep disorders and other associated problems.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

Last Updated: 15 Aug 2014

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Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

http://solvecfs.org/

Last Updated: 15 Aug 2014

View Details
Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

http://www.wicfs-me.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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General Resources

SolveCFS BioBank

The SolveCFS BioBank collects and stores a bank of biological samples and clinical information from individuals with CFS and unaffected individuals aged 10 and older.

Updated 6 Dec 2012

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Research1st News

Our free monthly e-newsletter, Research1st News, provides the latest research and policy news, as well as information about upcoming events and media coverage. Visit the archive to read past issues and to sign up to receive upcoming issues by email.

Updated 6 Dec 2012

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SolveCFS: The Chronicle of the CFIDS Association of America

The Association's print publication highlighting how the Association is advancing progress in CFS research and policy and it will share global news of interest to those who are committed to our cause.

Updated 6 Dec 2012

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ME.CFS. Toll free hotline.

Agencies can e mail us to ask for posters to display our hotline number so clients can attain disease information. IMPORTANT TO NOT discard those without computers.

Updated 1 Feb 2013

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Blogs

Research1st

This website is intended to become a one-stop shop for the most current and reliable information about CFS-related research being conducted by top-flight scientists worldwide.

Updated 6 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic fatigue syndrome" returned 659 free, full-text research articles on human participants. First 3 results:

IOM Recommends Renaming, Redefining Chronic Fatigue Syndrome.
 

Author(s):

Journal: Am Fam Physician. 2015 Apr;91(7):425.

 

Last Updated: 25 May 2016

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Suicide risk in people with chronic fatigue syndrome.
 

Author(s): Nav Kapur, Roger Webb

Journal: Lancet. 2016 Apr;387(10028):1596-7.

 

Last Updated: 27 Apr 2016

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Mortality of people with chronic fatigue syndrome: a retrospective cohort study in England and Wales from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) Clinical Record Interactive Search (CRIS) Register.
 

Author(s): Emmert Roberts, Simon Wessely, Trudie Chalder, Chin-Kuo Chang, Matthew Hotopf

Journal: Lancet. 2016 Apr;387(10028):1638-43.

 

Mortality associated with chronic fatigue syndrome is uncertain. We investigated mortality in individuals diagnosed with chronic fatigue syndrome in secondary and tertiary care using data from the South London and Maudsley NHS Foundation Trust Biomedical Research Centre (SLaM BRC) ...

Last Updated: 27 Apr 2016

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic fatigue syndrome" returned 66 free, full-text review articles on human participants. First 3 results:

Sleep Disturbances in Pediatric Chronic Fatigue Syndrome: A Review of Current Research.
 

Author(s): Kelli Snodgrass, Adrienne Harvey, Adam Scheinberg, Sarah Knight

Journal:

 

Children and adolescents with chronic fatigue syndrome (CFS) frequently report sleep disturbances. However, little is known about the nature and severity of sleep disturbance and factors associated with sleep problems in pediatric CFS. The purpose of this review was to synthesize ...

Last Updated: 28 Aug 2015

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Altered immune response to exercise in patients with chronic fatigue syndrome/myalgic encephalomyelitis: a systematic literature review.
 

Author(s): Jo Nijs, Andrea Nees, Lorna Paul, Margot De Kooning, Kelly Ickmans, Mira Meeus, Jessica Van Oosterwijck

Journal: Exerc Immunol Rev. 2014 ;20():94-116.

 

An increasing number of studies have examined how the immune system of patients with Chronic Fatigue Syndrome (CFS), or myalgic encephalomyelitis, responds to exercise. The objective of the present study was to systematically review the scientific literature addressing exercise-induced ...

Last Updated: 30 Jun 2014

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Case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME): a systematic review.
 

Author(s): Kjetil Gundro Brurberg, Marita Sporstøl Fønhus, Lillebeth Larun, Signe Flottorp, Kirsti Malterud

Journal:

 

To identify case definitions for chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME), and explore how the validity of case definitions can be evaluated in the absence of a reference standard.

Last Updated: 10 Feb 2014

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Reducing Orthostatic Intolerance With Oral Rehydration in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Patients
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome; Myalgic Encephalomyelitis; Systemic Exertion Intolerance Disease (SEID); Postural Tachycardia Syndrome (POTS); Neurally Mediated Syncope (NMS)

 

Last Updated: 29 Jul 2016

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Acupuncture for the Sleep Disorder of Chronic Fatigue Syndrome
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 6 Aug 2012

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Observational Research on Use of Immunoprop Supplement in Chronic Fatigue Syndrome
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 24 Jul 2013

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