Chronic fatigue syndrome

Common Name(s)

Chronic fatigue syndrome

Chronic fatigue syndrome is a condition that causes extreme, long-lasting fatigue which can limit the ability to participate in ordinary, daily activities. It generally occurs in young adults between the ages of 20 and 40. The main symptom of this condition is disabling fatigue that does not improve with rest. Other signs and symptoms may include muscle pain; joint pain; concentration and memory problems; headaches; sleep problems; fever; sore throat; and/or tender lymph nodes. The exact cause of chronic fatigue syndrome is not known, but it has been proposed that infectious agents, immune system impairment and/or hormonal system deregulation may be involved. There is no cure for this condition; the goal of treatment is to improve symptoms. Medications may be used to treat pain, sleep disorders and other associated problems.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

Last Updated: 15 Aug 2014

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Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

Last Updated: 20 Feb 2013

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General Support Organizations

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How do you compare to others with this condition?

Privately answer questions about your health. Let resources, you select, come to you.

Anonymously share and see how your answers compare with others with this condition while privately providing key pieces of information to medical researchers, disease advocacy groups, and others ONLY YOU select to help speed up cures and better alternatives.

 
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chronic fatigue syndrome" for support, advocacy or research.

Solve ME/CFS Initiative, Inc.

For CFS to be widely understood, diagnosable, curable and preventable.

http://solvecfs.org/

Last Updated: 15 Aug 2014

View Details
Wisconsin Myalgic Encephalomyelitis. Chronic Fatigue Syndrome Association, Inc.

The Wisconsin Chronic Fatigue Syndrome Association mission statement (1987): To act as a clearinghouse for CFS information, assist patients and their families, encourage communication among agencies, institutions, and concerned individuals and promote research on the cause, cure, and ultimate prevention of chronic fatigue syndrome.

http://www.wicfs-me.org

Last Updated: 20 Feb 2013

View Details

 

General Support Organizations

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General Resources

SolveCFS BioBank

The SolveCFS BioBank collects and stores a bank of biological samples and clinical information from individuals with CFS and unaffected individuals aged 10 and older.

Updated 6 Dec 2012

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Research1st News

Our free monthly e-newsletter, Research1st News, provides the latest research and policy news, as well as information about upcoming events and media coverage. Visit the archive to read past issues and to sign up to receive upcoming issues by email.

Updated 6 Dec 2012

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SolveCFS: The Chronicle of the CFIDS Association of America

The Association's print publication highlighting how the Association is advancing progress in CFS research and policy and it will share global news of interest to those who are committed to our cause.

Updated 6 Dec 2012

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ME.CFS. Toll free hotline.

Agencies can e mail us to ask for posters to display our hotline number so clients can attain disease information. IMPORTANT TO NOT discard those without computers.

Updated 1 Feb 2013

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Blogs

Research1st

This website is intended to become a one-stop shop for the most current and reliable information about CFS-related research being conducted by top-flight scientists worldwide.

Updated 6 Dec 2012

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chronic fatigue syndrome" returned 727 free, full-text research articles on human participants. First 3 results:

Reduction of Glucocorticoid Receptor Function in Chronic Fatigue Syndrome.
 

Author(s): Megan Lynn, Laura Maclachlan, Andreas Finkelmeyer, James Clark, James Locke, Stephen Todryk, Wan-Fai Ng, Julia L Newton, Stuart Watson

Journal:

 

Glucocorticoid receptor (GR) function may have aetiopathogenic significance in chronic fatigue syndrome (CFS), via its essential role in mediating inflammatory responses as well as in hypothalamic-pituitary-adrenal axis regulation. GR function can be estimated ex vivo by measuring ...

Last Updated: 31 Dec 1969

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Lower regulatory frequency for postural control in patients with fibromyalgia and chronic fatigue syndrome.
 

Author(s): Omid Rasouli, Ottar Vasseljen, Egil A Fors, Håvard W Lorås, Ann-Katrin Stensdotter

Journal:

 

As many similar symptoms are reported in fibromyalgia (FM) and chronic fatigue syndrome (CFS), underlying defcits may potentially also be similar. Postural disequilibrium reported in both conditions may thus be explained by similar deviations in postural control strategies. 75 females ...

Last Updated: 31 Dec 1969

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Treating patients suffering from myalgic encephalopathy/chronic fatigue syndrome (ME/CFS) with sodium dichloroacetate: An open-label, proof-of-principle pilot trial.
 

Author(s): Frank Comhaire

Journal: Med. Hypotheses. 2018 May;114():45-48.

 

Twenty-two consecutive patients suffering from refractory myalgic encephalitis/chronic fatigue syndrome (ME/CFS) were treated with an innovative nutriceutical containing sodium dichloroacetate in a proof-of-principle, pilot, open-label prospective cohort trial. Ten patients experienced ...

Last Updated: 31 Dec 1969

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chronic fatigue syndrome" returned 73 free, full-text review articles on human participants. First 3 results:

The effect of physiotherapy on fatigue and physical functioning in chronic fatigue syndrome patients: A systematic review.
 

Author(s): G Galeoto, J Sansoni, D Valenti, R Mollica, D Valente, M Parente, A Servadio

Journal: Clin Ter. ;169(4):e184-e188.

 

The objectives of this work were to fill the gap in the scientific literature and to evaluate the results of physical therapy treatments in individuals affected by chronic fatigue syndrome, considering only studies that employed a randomized controlled trial.

Last Updated: 31 Dec 1969

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Myalgic Encephalomyelitis/Chronic Fatigue Syndrome - Evidence for an autoimmune disease.
 

Author(s): Franziska Sotzny, Julià Blanco, Enrica Capelli, Jesús Castro-Marrero, Sophie Steiner, Modra Murovska, Carmen Scheibenbogen,

Journal: Autoimmun Rev. 2018 Jun;17(6):601-609.

 

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a frequent and severe chronic disease drastically impairing life quality. The underlying pathomechanism is incompletely understood yet but there is convincing evidence that in at least a subset of patients ME/CFS has an ...

Last Updated: 31 Dec 1969

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What treatments work for anxiety in children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME)? Systematic review.
 

Author(s): Sarah Victoria Ellen Stoll, Esther Crawley, Victoria Richards, Nishita Lal, Amberly Brigden, Maria E Loades

Journal:

 

Anxiety is more prevalent in children with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) than in the general population. A systematic review was carried out to identify which treatment methods are most effective for children with CFS and anxiety.

Last Updated: 31 Dec 1969

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 18 Apr 2018

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Myalgic Encephalomyelitis Chronic Fatigue at the National Institutes of Health
 

Status: Recruiting

Condition Summary: Chronic Fatigue Syndrome

 

Last Updated: 5 Oct 2018

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Clinical Trial to Investigate CT38 in the Treatment of Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
 

Status: Recruiting

Condition Summary: Myalgic Encephalomyelitis; Chronic Fatigue Syndrome

 

Last Updated: 27 Jul 2018

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