Chiari malformation type 1

Common Name(s)

Chiari malformation type 1

Chiari malformation type 1 is a structural abnormality of the cerebellum, the part of the brain that controls balance. It involves the extension of the lower part of the cerebellum into the foramen magnum (the large hole at the base of the skull which allows passage of the spinal cord), without involving the brainstem. Normally, only the spinal cord passes through this opening. This malformation is the most common type of Chiari malformation and may not cause any symptoms. Depending on the symptoms present and severity, some individuals may not require treatment while others may require pain medications or surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chiari malformation type 1" for support, advocacy or research.

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American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chiari malformation type 1" for support, advocacy or research.

Logo
American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

http://www.asap.org

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chiari malformation type 1" returned 20 free, full-text research articles on human participants. First 3 results:

Comparison of the Surgical Results for Foramen Magnum Decompression with and without Duraplasty in Chiari Malformation Type 1.
 

Author(s): Mehmet Sabri Gurbuz, Numan Karaaslan, Tezcan Caliskan, Emre Unal, Mehmet Zafer Berkman

Journal: Turk Neurosurg. 2015 ;25(3):419-24.

 

The surgical results for foramen magnum decompression (FMD) with and without duraplasty in Chiari Malformation type 1 (CM-1) were compared retrospectively.

Last Updated: 3 Jun 2015

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Risks and outcomes of spinal deformity surgery in Chiari malformation, Type 1, with syringomyelia versus adolescent idiopathic scoliosis.
 

Author(s): Jakub Godzik, Terrence F Holekamp, David D Limbrick, Lawrence G Lenke, T S Park, Wilson Z Ray, Keith H Bridwell, Michael P Kelly

Journal: Spine J. 2015 Sep;15(9):2002-8.

 

Chiari malformation, Type 1, with syringomyelia (CIM+SM) is often associated with spinal deformity. The safety of scoliosis surgery this population is controversial and has never been directly compared with adolescent idiopathic scoliosis (AIS).

Last Updated: 25 Aug 2015

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Validation of an International Classification of Diseases, Ninth Revision Code Algorithm for Identifying Chiari Malformation Type 1 Surgery in Adults.
 

Author(s): Jacob K Greenberg, Travis R Ladner, Margaret A Olsen, Chevis N Shannon, Jingxia Liu, Chester K Yarbrough, Jay F Piccirillo, John C Wellons, Matthew D Smyth, Tae Sung Park, David D Limbrick

Journal: Neurosurgery. 2015 Aug;77(2):269-73.

 

The use of administrative billing data may enable large-scale assessments of treatment outcomes for Chiari Malformation type I (CM-1). However, to utilize such data sets, validated International Classification of Diseases, Ninth Revision (ICD-9-CM) code algorithms for identifying ...

Last Updated: 18 Jul 2015

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chiari malformation type 1" returned 3 free, full-text review articles on human participants. First 3 results:

Surgical History of Sleep Apnea in Pediatric Patients with Chiari Type 1 Malformation.
 

Author(s): Isaac Jonathan Pomeraniec, Alexander Ksendzovsky, Pearl L Yu, John A Jane

Journal: Neurosurg. Clin. N. Am.. 2015 Oct;26(4):543-53.

 

Sleep apnea represents a relative indication for posterior fossa decompression in pediatric patients with Chiari malformation type 1. Duraplasty was associated with improvement of sleep apnea in 100% of patients and dural splitting with improvement in 50% of patients. Duraplasty and ...

Last Updated: 26 Sep 2015

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Chiari type 1 malformation in a pseudotumour cerebri patient: is it an acquired or congenital Chiari malformation?
 

Author(s): Seref Istek

Journal:

 

Chiari malformation type 1 (CM1) is a developmental abnormality of the cerebellar tonsils. Patients with CM1 commonly present with headache. Papilloedema is rarely seen in CM1. However, a 52-year-old woman presented to the hospital with a headache and her ophthalmological examination ...

Last Updated: 6 Jun 2014

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A patient with optic pathway glioma, scoliosis, Chiari type I malformation and syringomyelia: is it Neurofibromatosis type 1?
 

Author(s): A Chakravarty, A Bhargava, S Nandy

Journal: Neurol India. 2002 Dec;50(4):520-1.

 

A 22 years old girl had features of optic pathway glioma, scoliosis, Chiari type 1 malformation and cervical syringomyelia. She had no cutaneous lesions. We considered this combination to be more than coincidental and argue in favour of considering the case as a variant form of Neurofibromatosis ...

Last Updated: 10 Feb 2003

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Posterior Fossa Decompression With or Without Duraplasty for Chiari Type I Malformation With Syringomyelia
 

Status: Not yet recruiting

Condition Summary: Arnold-Chiari Malformation, Type 1; Chiari Malformation Type I; Type I Arnold-Chiari Malformation; Syringomyelia

 

Last Updated: 27 Apr 2016

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Genetic Analysis of the Chiari I Malformation
 

Status: Recruiting

Condition Summary: Syringomyelia; Type I Arnold Chiari Malformation

 

Last Updated: 6 Oct 2016

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