Chiari malformation type 1

Common Name(s)

Chiari malformation type 1

Chiari malformation type 1 is a structural abnormality of the cerebellum, the part of the brain that controls balance. It involves the extension of the lower part of the cerebellum into the foramen magnum (the large hole at the base of the skull which allows passage of the spinal cord), without involving the brainstem. Normally, only the spinal cord passes through this opening. This malformation is the most common type of Chiari malformation and may not cause any symptoms. Depending on the symptoms present and severity, some individuals may not require treatment while others may require pain medications or surgery.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chiari malformation type 1" for support, advocacy or research.

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American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

Last Updated: 18 Mar 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Chiari malformation type 1" for support, advocacy or research.

Logo
American Syringomyelia & Chiari Alliance Project, Inc.

To improve the lives of people affected by syringomyelia, Chiari malformation and related disorders, while we find the cure.

http://www.asap.org

Last Updated: 30 Oct 2012

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Chiari & Syringomyelia Foundation

Our mission is to advance knowledge through research and to educate the medical, allied sciences, and lay community about Chiari malformation, syringomyelia and related CSF (cerebrospinal fluid) disorders.

http://www.CSFinfo.org

Last Updated: 18 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Chiari malformation type 1" returned 12 free, full-text research articles on human participants. First 3 results:

Arnold-Chiari 1 malformation type 1 with syringohydromyelia presenting as acute tetraparesis: a case report.
 

Author(s): Byron Schneider, Pravardhan Birthi, Sara Salles

Journal: J Spinal Cord Med. 2013 Mar;36(2):161-5.

 

A 19-year-old woman who presented to a community hospital after awakening with tetraparesis, generalized paresthesia, and severe neck pain, and was transferred to an acute care hospital.

Last Updated: 1 Jul 2013

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Complex sleep apnea syndrome in a child with Chiari malformation type 1.
 

Author(s): Sebnem Yosunkaya, Sevgi Pekcan

Journal: Turk. J. Pediatr.. ;55(1):107-11.

 

There are few reports of a patient presenting with symptoms of obstructive sleep apnea syndrome (OSAS) as the sole manifestation of Chiari malformation type 1 (CM1). In the literature, complex sleep apnea syndrome (CompSAS) was also reported as a rare condition related to CM1 patients. ...

Last Updated: 22 May 2013

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[Sleep apnea-hypopnea syndrome in type 1 Chiari malformation].
 

Author(s): M A Baena-Gómez, J Torres-Borrego, A B Molina Terán, D Alvarez Gil, A M Collantes Herrera

Journal: An Pediatr (Barc). 2013 Oct;79(4):273-4.

 

Last Updated: 25 Sep 2013

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Chiari malformation type 1" returned 1 free, full-text review articles on human participants. First 3 results:

A patient with optic pathway glioma, scoliosis, Chiari type I malformation and syringomyelia: is it Neurofibromatosis type 1?
 

Author(s): A Chakravarty, A Bhargava, S Nandy

Journal: Neurol India. 2002 Dec;50(4):520-1.

 

A 22 years old girl had features of optic pathway glioma, scoliosis, Chiari type 1 malformation and cervical syringomyelia. She had no cutaneous lesions. We considered this combination to be more than coincidental and argue in favour of considering the case as a variant form of Neurofibromatosis ...

Last Updated: 10 Feb 2003

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in GeneReviews.

There are currently no related results available in Genetic Testing Registry.

 
 
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Clinical Trial Information This information is provided by ClinicalTrials.gov

Genetic Analysis of the Chiari I Malformation
 

Status: Recruiting

Condition Summary: Syringomyelia; Type I Arnold Chiari Malformation

 

Last Updated: 11 Nov 2014

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The Genetics of Chiari Type I Malformation
 

Status: Recruiting

Condition Summary: Chiari Type I Malformation

 

Last Updated: 11 Sep 2014

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