Central post-stroke pain

Common Name(s)

Central post-stroke pain

Central post-stroke pain (CPSP) is a rare neurological disorder in which the body becomes hypersensitive to pain as a result of damage to the thalamus, a part of the brain that affects sensation. Primary symptoms are pain and loss of sensation, usually in the face, arms, and/or legs. Pain or discomfort may be felt after being mildly touched or even in the absence of a stimulus; the pain may worsen by exposure to heat or cold and by emotional distress. It is caused by damage to, or dysfunction of, the central nervous system (CNS), which may be due to stroke, multiple sclerosis, tumors, epilepsy, brain or spinal cord trauma, or Parkinson's disease. Treatment typically includes pain medications to provide some reduction of pain, but complete relief of pain may not be possible. Tricyclic antidepressants or anticonvulsants can sometimes be useful. Lowering stress levels appears to reduce pain.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Central post-stroke pain" for support, advocacy or research.

US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Central post-stroke pain" for support, advocacy or research.

US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Central post-stroke pain" returned 3 free, full-text research articles on human participants. First 3 results:

Assessing the risk of central post-stroke pain of thalamic origin by lesion mapping.
 

Author(s): Till Sprenger, Christian L Seifert, Michael Valet, Anna P Andreou, Annette Foerschler, Claus Zimmer, D Louis Collins, Peter J Goadsby, Thomas R Tölle, M Mallar Chakravarty

Journal: Brain. 2012 Aug;135(Pt 8):2536-45.

 

Central post-stroke pain of thalamic origin is an extremely distressing and often refractory disorder. There are no well-established predictors for pain development after thalamic stroke, and the role of different thalamic nuclei is unclear. Here, we used structural magnetic resonance ...

Last Updated: 30 Jul 2012

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Efficacy of motor cortex stimulation for intractable central neuropathic pain: comparison of stimulation parameters between post-stroke pain and other central pain.
 

Author(s): Takafumi Tanei, Yasukazu Kajita, Hiroshi Noda, Shigenori Takebayashi, Daisuke Nakatsubo, Satoshi Maesawa, Toshihiko Wakabayashi

Journal: Neurol. Med. Chir. (Tokyo). 2011 ;51(1):8-14.

 

Motor cortex stimulation (MCS) has now become the preferred option for neurosurgical management of intractable central neuropathic pain such as post-stroke pain and trigeminal neuropathic pain. However, the efficacy of MCS for other central neuropathic pain such as pain resulting ...

Last Updated: 28 Jan 2011

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Analgesia in conjunction with normalisation of thermal sensation following deep brain stimulation for central post-stroke pain.
 

Author(s): Anthony E Pickering, Simon R Thornton, Sarah J Love-Jones, Charlotte Steeds, Nikunj K Patel

Journal: Pain. 2009 Dec;147(1-3):299-304.

 

The aetiology of central post-stroke pain (CPSP) is poorly understood and such pains are often refractory to treatment. We report the case of a 56-year-old man, who, following a temporo-parietal infarct, suffered from debilitating and refractory hemi-body cold dysaesthesia and severe ...

Last Updated: 25 Nov 2009

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Central post-stroke pain" returned 1 free, full-text review articles on human participants. First 3 results:

The management of central post-stroke pain.
 

Author(s): D Bowsher

Journal: Postgrad Med J. 1995 Oct;71(840):598-604.

 

Central post-stroke pain (CPSP) used to be known as 'thalamic syndrome'. Early post-mortem studies showed that many cases had extrathalamic lesions, and modern imaging methods have confirmed and extended these findings. CPSP affects between 2 and 6% of stroke patients, ie, there is ...

Last Updated: 13 Feb 1996

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Symptoms, Diagnosis, and Treatment

There are currently no related results available in Genetics Home Reference.

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Peripheral Sensory Input in Central Post Stroke Pain (CPSP)
 

Status: Not yet recruiting

Condition Summary: Central Post Stroke Pain

 

Last Updated: 27 May 2014

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Gait Parameters Analysis in Post-stroke Patients and in Elderly Fallers
 

Status: Recruiting

Condition Summary: Healthy; Thalamic Pain Syndrome; Fallers

 

Last Updated: 11 Apr 2014

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Deep rTMS in Central Neuropathic Pain Syndromes
 

Status: Recruiting

Condition Summary: Pain; Spinal Cord Injury; Post Stroke Pain

 

Last Updated: 29 Aug 2013

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